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Showing 1 to 8 of 8 entries
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Role of adaptor proteins in secretory granule biogenesis and maturation.

Frontiers in endocrinology

Bonnemaison ML, Eipper BA, Mains RE.
PMID: 23966980
Front Endocrinol (Lausanne). 2013 Aug 14;4:101. doi: 10.3389/fendo.2013.00101. eCollection 2013.

In the regulated secretory pathway, secretory granules (SGs) store peptide hormones that are released on demand. SGs are formed at the trans-Golgi network and must undergo a maturation process to become responsive to secretagogues. The production of mature SGs...

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Bonnemaison ML, Eipper BA, Mains RE. Role of adaptor proteins in secretory granule biogenesis and maturation. Front Endocrinol (Lausanne). 2013;4:101doi: 10.3389/fendo.2013.00101.
Bonnemaison, M. L., Eipper, B. A., & Mains, R. E. (2013). Role of adaptor proteins in secretory granule biogenesis and maturation. Frontiers in endocrinology, 4101. https://doi.org/10.3389/fendo.2013.00101
Bonnemaison, Mathilde L, et al. "Role of adaptor proteins in secretory granule biogenesis and maturation." Frontiers in endocrinology vol. 4 (2013): 101. doi: https://doi.org/10.3389/fendo.2013.00101
Bonnemaison ML, Eipper BA, Mains RE. Role of adaptor proteins in secretory granule biogenesis and maturation. Front Endocrinol (Lausanne). 2013 Aug 14;4:101. doi: 10.3389/fendo.2013.00101. eCollection 2013. PMID: 23966980; PMCID: PMC3743005.
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Global Approaches to the Role of miRNAs in Drug-Induced Changes in Gene Expression.

Frontiers in genetics

Eipper-Mains JE, Eipper BA, Mains RE.
PMID: 22707957
Front Genet. 2012 Jun 13;3:109. doi: 10.3389/fgene.2012.00109. eCollection 2012.

Neurons modulate gene expression with subcellular precision through excitation-coupled local protein synthesis, a process that is regulated in part through the involvement of microRNAs (miRNAs), a class of small non-coding RNAs. The biosynthesis of miRNAs is reviewed, with special...

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Eipper-Mains JE, Eipper BA, Mains RE. Global Approaches to the Role of miRNAs in Drug-Induced Changes in Gene Expression. Front Genet. 2012;3:109doi: 10.3389/fgene.2012.00109.
Eipper-Mains, J. E., Eipper, B. A., & Mains, R. E. (2012). Global Approaches to the Role of miRNAs in Drug-Induced Changes in Gene Expression. Frontiers in genetics, 3109. https://doi.org/10.3389/fgene.2012.00109
Eipper-Mains, Jodi E, et al. "Global Approaches to the Role of miRNAs in Drug-Induced Changes in Gene Expression." Frontiers in genetics vol. 3 (2012): 109. doi: https://doi.org/10.3389/fgene.2012.00109
Eipper-Mains JE, Eipper BA, Mains RE. Global Approaches to the Role of miRNAs in Drug-Induced Changes in Gene Expression. Front Genet. 2012 Jun 13;3:109. doi: 10.3389/fgene.2012.00109. eCollection 2012. PMID: 22707957; PMCID: PMC3374462.
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Synaptic plasticity, a symphony in GEF.

ACS chemical neuroscience

Kiraly DD, Eipper-Mains JE, Mains RE, Eipper BA.
PMID: 20543890
ACS Chem Neurosci. 2010 May 19;1(5):348-365. doi: 10.1021/cn100012x.

Dendritic spines are the postsynaptic sites for the majority of excitatory synapses in the mammalian forebrain. While many spines display great stability, others change shape in a matter of seconds to minutes. These rapid alterations in dendritic spine number...

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Kiraly DD, Eipper-Mains JE, Mains RE, et al. Synaptic plasticity, a symphony in GEF. ACS Chem Neurosci. 2010;1(5):348-365doi: 10.1021/cn100012x.
Kiraly, D. D., Eipper-Mains, J. E., Mains, R. E., & Eipper, B. A. (2010). Synaptic plasticity, a symphony in GEF. ACS chemical neuroscience, 1(5), 348-365. https://doi.org/10.1021/cn100012x
Kiraly, Drew D, et al. "Synaptic plasticity, a symphony in GEF." ACS chemical neuroscience vol. 1,5 (2010): 348-365. doi: https://doi.org/10.1021/cn100012x
Kiraly DD, Eipper-Mains JE, Mains RE, Eipper BA. Synaptic plasticity, a symphony in GEF. ACS Chem Neurosci. 2010 May 19;1(5):348-365. doi: 10.1021/cn100012x. PMID: 20543890; PMCID: PMC2882301.
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Sex-Specific Gene Expression in the Mouse Nucleus Accumbens Before and After Cocaine Exposure.

Journal of the Endocrine Society

LaRese TP, Rheaume BA, Abraham R, Eipper BA, Mains RE.
PMID: 30746506
J Endocr Soc. 2019 Jan 14;3(2):468-487. doi: 10.1210/js.2018-00313. eCollection 2019 Feb 01.

The nucleus accumbens plays a major role in the response of mammals to cocaine. In animal models and human studies, the addictive effects of cocaine and relapse probability have been shown to be greater in females. Sex-specific differential expression...

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LaRese TP, Rheaume BA, Abraham R, et al. Sex-Specific Gene Expression in the Mouse Nucleus Accumbens Before and After Cocaine Exposure. J Endocr Soc. 2019;3(2):468-487doi: 10.1210/js.2018-00313.
LaRese, T. P., Rheaume, B. A., Abraham, R., Eipper, B. A., & Mains, R. E. (2019). Sex-Specific Gene Expression in the Mouse Nucleus Accumbens Before and After Cocaine Exposure. Journal of the Endocrine Society, 3(2), 468-487. https://doi.org/10.1210/js.2018-00313
LaRese, Taylor P, et al. "Sex-Specific Gene Expression in the Mouse Nucleus Accumbens Before and After Cocaine Exposure." Journal of the Endocrine Society vol. 3,2 (2019): 468-487. doi: https://doi.org/10.1210/js.2018-00313
LaRese TP, Rheaume BA, Abraham R, Eipper BA, Mains RE. Sex-Specific Gene Expression in the Mouse Nucleus Accumbens Before and After Cocaine Exposure. J Endocr Soc. 2019 Jan 14;3(2):468-487. doi: 10.1210/js.2018-00313. eCollection 2019 Feb 01. PMID: 30746506; PMCID: PMC6364626.
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Transcriptional Profiling of Non-injured Nociceptors After Spinal Cord Injury Reveals Diverse Molecular Changes.

Frontiers in molecular neuroscience

Yasko JR, Moss IL, Mains RE.
PMID: 32038157
Front Mol Neurosci. 2019 Nov 26;12:284. doi: 10.3389/fnmol.2019.00284. eCollection 2019.

Traumatic spinal cord injury (SCI) has devastating implications for patients, including a high predisposition for developing chronic pain distal to the site of injury. Chronic pain develops weeks to months after injury, consequently, patients are treated after irreparable changes...

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Yasko JR, Moss IL, Mains RE. Transcriptional Profiling of Non-injured Nociceptors After Spinal Cord Injury Reveals Diverse Molecular Changes. Front Mol Neurosci. 2019;12:284doi: 10.3389/fnmol.2019.00284.
Yasko, J. R., Moss, I. L., & Mains, R. E. (2019). Transcriptional Profiling of Non-injured Nociceptors After Spinal Cord Injury Reveals Diverse Molecular Changes. Frontiers in molecular neuroscience, 12284. https://doi.org/10.3389/fnmol.2019.00284
Yasko, Jessica R, et al. "Transcriptional Profiling of Non-injured Nociceptors After Spinal Cord Injury Reveals Diverse Molecular Changes." Frontiers in molecular neuroscience vol. 12 (2019): 284. doi: https://doi.org/10.3389/fnmol.2019.00284
Yasko JR, Moss IL, Mains RE. Transcriptional Profiling of Non-injured Nociceptors After Spinal Cord Injury Reveals Diverse Molecular Changes. Front Mol Neurosci. 2019 Nov 26;12:284. doi: 10.3389/fnmol.2019.00284. eCollection 2019. PMID: 32038157; PMCID: PMC6988781.
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Cell-type specific knockout of peptidylglycine α-amidating monooxygenase reveals specific behavioral roles in excitatory forebrain neurons and cardiomyocytes.

Genes, brain, and behavior

Powers KG, Ma XM, Eipper BA, Mains RE.
PMID: 32902163
Genes Brain Behav. 2021 Feb;20(2):e12699. doi: 10.1111/gbb.12699. Epub 2020 Sep 24.

Neuropeptides and peptide hormones play a crucial role in integrating the many factors that affect physiologic and cognitive processes. The potency of many of these peptides requires an amidated amino acid at the C-terminus; a single enzyme, peptidylglycine α-amidating...

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Powers KG, Ma XM, Eipper BA, et al. Cell-type specific knockout of peptidylglycine α-amidating monooxygenase reveals specific behavioral roles in excitatory forebrain neurons and cardiomyocytes. Genes Brain Behav. 2020;20(2):e12699doi: 10.1111/gbb.12699.
Powers, K. G., Ma, X. M., Eipper, B. A., & Mains, R. E. (2021). Cell-type specific knockout of peptidylglycine α-amidating monooxygenase reveals specific behavioral roles in excitatory forebrain neurons and cardiomyocytes. Genes, brain, and behavior, 20(2), e12699. https://doi.org/10.1111/gbb.12699
Powers, Kathryn G, et al. "Cell-type specific knockout of peptidylglycine α-amidating monooxygenase reveals specific behavioral roles in excitatory forebrain neurons and cardiomyocytes." Genes, brain, and behavior vol. 20,2 (2021): e12699. doi: https://doi.org/10.1111/gbb.12699
Powers KG, Ma XM, Eipper BA, Mains RE. Cell-type specific knockout of peptidylglycine α-amidating monooxygenase reveals specific behavioral roles in excitatory forebrain neurons and cardiomyocytes. Genes Brain Behav. 2021 Feb;20(2):e12699. doi: 10.1111/gbb.12699. Epub 2020 Sep 24. PMID: 32902163; PMCID: PMC7858240.
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Kalirin/Trio Rho GDP/GTP exchange factors regulate proinsulin and insulin secretion.

Journal of molecular endocrinology

Dufurrena Q, Bäck N, Mains RE, Hodgson L, Tanowitz H, Mandela P, Eipper E, Kuliawat R.
PMID: 30407917
J Mol Endocrinol. 2018 Nov 01; doi: 10.1530/JME-18-0048. Epub 2018 Nov 01.

Key features for progression to pancreatic β-cell failure and disease are loss of glucose responsiveness and an increased ratio of secreted proinsulin to insulin. Proinsulin and insulin are stored in secretory granules (SGs) and the fine-tuning of hormone output...

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Dufurrena Q, Bäck N, Mains RE, et al. Kalirin/Trio Rho GDP/GTP exchange factors regulate proinsulin and insulin secretion. J Mol Endocrinol. 2018;doi: 10.1530/JME-18-0048.
Dufurrena, Q., Bäck, N., Mains, R. E., Hodgson, L., Tanowitz, H., Mandela, P., Eipper, E., & Kuliawat, R. (2018). Kalirin/Trio Rho GDP/GTP exchange factors regulate proinsulin and insulin secretion. Journal of molecular endocrinology, . https://doi.org/10.1530/JME-18-0048
Dufurrena, Quinn, et al. "Kalirin/Trio Rho GDP/GTP exchange factors regulate proinsulin and insulin secretion." Journal of molecular endocrinology vol. (2018). doi: https://doi.org/10.1530/JME-18-0048
Dufurrena Q, Bäck N, Mains RE, Hodgson L, Tanowitz H, Mandela P, Eipper E, Kuliawat R. Kalirin/Trio Rho GDP/GTP exchange factors regulate proinsulin and insulin secretion. J Mol Endocrinol. 2018 Nov 01; doi: 10.1530/JME-18-0048. Epub 2018 Nov 01. PMID: 30407917; PMCID: PMC6494717.
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Chronic pain following spinal cord injury: Current approaches to cellular and molecular mechanisms.

Trends in cell & molecular biology

Yasko JR, Mains RE.
PMID: 33564218
Trends Cell Mol Biol. 2018;13:67-84.

Traumatic spinal cord injury (SCI) has devastating implications for patients, including a high prevalence of chronic pain. Despite advancements in our understanding of the mechanisms involved post-SCI, there are no effective treatments for chronic pain following injury. The development...

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Yasko JR, Mains RE. Chronic pain following spinal cord injury: Current approaches to cellular and molecular mechanisms. Trends Cell Mol Biol. 2018;13:67-84
Yasko, J. R., & Mains, R. E. (2018). Chronic pain following spinal cord injury: Current approaches to cellular and molecular mechanisms. Trends in cell & molecular biology, 1367-84.
Yasko, Jessica R, and Mains, Richard E. "Chronic pain following spinal cord injury: Current approaches to cellular and molecular mechanisms." Trends in cell & molecular biology vol. 13 (2018): 67-84.
Yasko JR, Mains RE. Chronic pain following spinal cord injury: Current approaches to cellular and molecular mechanisms. Trends Cell Mol Biol. 2018;13:67-84. PMID: 33564218; PMCID: PMC7869846.
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Showing 1 to 8 of 8 entries