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Prevalence, Awareness, and Treatment of Hypertension in Hispanics/Latinos With CKD in the Hispanic Community Health Study/Study of Latinos.

Kidney medicine

Lora CM, Ricardo AC, Chen J, Franceschini N, Kramer HJ, Melamed ML, Raij L, Rosas SE, Schneiderman N, Daviglus M, Lash JP.
PMID: 32734253
Kidney Med. 2020 Apr 21;2(3):332-340. doi: 10.1016/j.xkme.2020.02.005. eCollection 2020.

RATIONALE & OBJECTIVE: Lower rates of hypertension awareness, treatment, and control have been observed in Hispanics/Latinos compared with non-Hispanic whites. These factors have not been studied in Hispanics/Latinos with chronic kidney disease (CKD). We sought to describe the prevalence,...

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Lora CM, Ricardo AC, Chen J, et al. Prevalence, Awareness, and Treatment of Hypertension in Hispanics/Latinos With CKD in the Hispanic Community Health Study/Study of Latinos. Kidney Med. 2020;2(3):332-340doi: 10.1016/j.xkme.2020.02.005.
Lora, C. M., Ricardo, A. C., Chen, J., Franceschini, N., Kramer, H. J., Melamed, M. L., Raij, L., Rosas, S. E., Schneiderman, N., Daviglus, M., & Lash, J. P. (2020). Prevalence, Awareness, and Treatment of Hypertension in Hispanics/Latinos With CKD in the Hispanic Community Health Study/Study of Latinos. Kidney medicine, 2(3), 332-340. https://doi.org/10.1016/j.xkme.2020.02.005
Lora, Claudia M, et al. "Prevalence, Awareness, and Treatment of Hypertension in Hispanics/Latinos With CKD in the Hispanic Community Health Study/Study of Latinos." Kidney medicine vol. 2,3 (2020): 332-340. doi: https://doi.org/10.1016/j.xkme.2020.02.005
Lora CM, Ricardo AC, Chen J, Franceschini N, Kramer HJ, Melamed ML, Raij L, Rosas SE, Schneiderman N, Daviglus M, Lash JP. Prevalence, Awareness, and Treatment of Hypertension in Hispanics/Latinos With CKD in the Hispanic Community Health Study/Study of Latinos. Kidney Med. 2020 Apr 21;2(3):332-340. doi: 10.1016/j.xkme.2020.02.005. eCollection 2020. PMID: 32734253; PMCID: PMC7380346.
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Integrative analysis of 3604 GWAS reveals multiple novel cell type-specific regulatory associations.

Genome biology

Breeze CE, Haugen E, Reynolds A, Teschendorff A, van Dongen J, Lan Q, Rothman N, Bourque G, Dunham I, Beck S, Stamatoyannopoulos J, Franceschini N, Berndt SI.
PMID: 34996498
Genome Biol. 2022 Jan 07;23(1):13. doi: 10.1186/s13059-021-02560-3.

BACKGROUND: Genome-wide association study (GWAS) single nucleotide polymorphisms (SNPs) are known to preferentially co-locate to active regulatory elements in tissues and cell types relevant to disease aetiology. Further characterisation of associated cell type-specific regulation can broaden our understanding of...

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Breeze CE, Haugen E, Reynolds A, et al. Integrative analysis of 3604 GWAS reveals multiple novel cell type-specific regulatory associations. Genome Biol. 2022;23(1):13doi: 10.1186/s13059-021-02560-3.
Breeze, C. E., Haugen, E., Reynolds, A., Teschendorff, A., van Dongen, J., Lan, Q., Rothman, N., Bourque, G., Dunham, I., Beck, S., Stamatoyannopoulos, J., Franceschini, N., & Berndt, S. I. (2022). Integrative analysis of 3604 GWAS reveals multiple novel cell type-specific regulatory associations. Genome biology, 23(1), 13. https://doi.org/10.1186/s13059-021-02560-3
Breeze, Charles E, et al. "Integrative analysis of 3604 GWAS reveals multiple novel cell type-specific regulatory associations." Genome biology vol. 23,1 (2022): 13. doi: https://doi.org/10.1186/s13059-021-02560-3
Breeze CE, Haugen E, Reynolds A, Teschendorff A, van Dongen J, Lan Q, Rothman N, Bourque G, Dunham I, Beck S, Stamatoyannopoulos J, Franceschini N, Berndt SI. Integrative analysis of 3604 GWAS reveals multiple novel cell type-specific regulatory associations. Genome Biol. 2022 Jan 07;23(1):13. doi: 10.1186/s13059-021-02560-3. PMID: 34996498; PMCID: PMC8742386.
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DNAm-based signatures of accelerated aging and mortality in blood are associated with low renal function.

Clinical epigenetics

Matías-García PR, Ward-Caviness CK, Raffield LM, Gao X, Zhang Y, Wilson R, Gào X, Nano J, Bostom A, Colicino E, Correa A, Coull B, Eaton C, Hou L, Just AC, Kunze S, Lange L, Lange E, Lin X, Liu S, Nwanaji-Enwerem JC, Reiner A, Shen J, Schöttker B, Vokonas P, Zheng Y, Young B, Schwartz J, Horvath S, Lu A, Whitsel EA, Koenig W, Adamski J, Winkelmann J, Brenner H, Baccarelli AA, Gieger C, Peters A, Franceschini N, Waldenberger M.
PMID: 34078457
Clin Epigenetics. 2021 Jun 02;13(1):121. doi: 10.1186/s13148-021-01082-w.

BACKGROUND: The difference between an individual's chronological and DNA methylation predicted age (DNAmAge), termed DNAmAge acceleration (DNAmAA), can capture life-long environmental exposures and age-related physiological changes reflected in methylation status. Several studies have linked DNAmAA to morbidity and mortality,...

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Matías-García PR, Ward-Caviness CK, Raffield LM, et al. DNAm-based signatures of accelerated aging and mortality in blood are associated with low renal function. Clin Epigenetics. 2021;13(1):121doi: 10.1186/s13148-021-01082-w.
Matías-García, P. R., Ward-Caviness, C. K., Raffield, L. M., Gao, X., Zhang, Y., Wilson, R., Gào, X., Nano, J., Bostom, A., Colicino, E., Correa, A., Coull, B., Eaton, C., Hou, L., Just, A. C., Kunze, S., Lange, L., Lange, E., Lin, X., Liu, S., Nwanaji-Enwerem, J. C., Reiner, A., Shen, J., Schöttker, B., Vokonas, P., Zheng, Y., Young, B., Schwartz, J., Horvath, S., Lu, A., Whitsel, E. A., Koenig, W., Adamski, J., Winkelmann, J., Brenner, H., Baccarelli, A. A., Gieger, C., Peters, A., Franceschini, N., & Waldenberger, M. (2021). DNAm-based signatures of accelerated aging and mortality in blood are associated with low renal function. Clinical epigenetics, 13(1), 121. https://doi.org/10.1186/s13148-021-01082-w
Matías-García, Pamela R, et al. "DNAm-based signatures of accelerated aging and mortality in blood are associated with low renal function." Clinical epigenetics vol. 13,1 (2021): 121. doi: https://doi.org/10.1186/s13148-021-01082-w
Matías-García PR, Ward-Caviness CK, Raffield LM, Gao X, Zhang Y, Wilson R, Gào X, Nano J, Bostom A, Colicino E, Correa A, Coull B, Eaton C, Hou L, Just AC, Kunze S, Lange L, Lange E, Lin X, Liu S, Nwanaji-Enwerem JC, Reiner A, Shen J, Schöttker B, Vokonas P, Zheng Y, Young B, Schwartz J, Horvath S, Lu A, Whitsel EA, Koenig W, Adamski J, Winkelmann J, Brenner H, Baccarelli AA, Gieger C, Peters A, Franceschini N, Waldenberger M. DNAm-based signatures of accelerated aging and mortality in blood are associated with low renal function. Clin Epigenetics. 2021 Jun 02;13(1):121. doi: 10.1186/s13148-021-01082-w. PMID: 34078457; PMCID: PMC8170969.
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Metabolome-wide association study of estimated glomerular filtration rates in Hispanics.

Kidney international

Lin BM, Zhang Y, Yu B, Boerwinkle E, Thygarajan B, Yunes M, Daviglus ML, Qi Q, Kaplan R, Lash J, Cai J, Sofer T, Franceschini N.
PMID: 34774559
Kidney Int. 2022 Jan;101(1):144-151. doi: 10.1016/j.kint.2021.09.032. Epub 2021 Nov 10.

Circulating metabolites are by-products of endogenous metabolism or exogenous sources and may inform disease states. Our study aimed to identify the source of variability in the association of metabolites with estimated glomerular filtration rate (eGFR) in Hispanics/Latinos with low...

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Lin BM, Zhang Y, Yu B, et al. Metabolome-wide association study of estimated glomerular filtration rates in Hispanics. Kidney Int. 2021;101(1):144-151doi: 10.1016/j.kint.2021.09.032.
Lin, B. M., Zhang, Y., Yu, B., Boerwinkle, E., Thygarajan, B., Yunes, M., Daviglus, M. L., Qi, Q., Kaplan, R., Lash, J., Cai, J., Sofer, T., & Franceschini, N. (2022). Metabolome-wide association study of estimated glomerular filtration rates in Hispanics. Kidney international, 101(1), 144-151. https://doi.org/10.1016/j.kint.2021.09.032
Lin, Bridget M, et al. "Metabolome-wide association study of estimated glomerular filtration rates in Hispanics." Kidney international vol. 101,1 (2022): 144-151. doi: https://doi.org/10.1016/j.kint.2021.09.032
Lin BM, Zhang Y, Yu B, Boerwinkle E, Thygarajan B, Yunes M, Daviglus ML, Qi Q, Kaplan R, Lash J, Cai J, Sofer T, Franceschini N. Metabolome-wide association study of estimated glomerular filtration rates in Hispanics. Kidney Int. 2022 Jan;101(1):144-151. doi: 10.1016/j.kint.2021.09.032. Epub 2021 Nov 10. PMID: 34774559; PMCID: PMC8741745.
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Effect of Sickle Cell Trait and .

Clinical journal of the American Society of Nephrology : CJASN

Reiner AP, Raffield LM, Franceschini N, Auer PL, Lange EM, Nickerson DA, Zakai NA, Correa A, Olson N.
PMID: 33268503
Clin J Am Soc Nephrol. 2021 Feb 08;16(2):287-289. doi: 10.2215/CJN.12100720. Epub 2020 Dec 02.

No abstract available.

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Reiner AP, Raffield LM, Franceschini N, et al. Effect of Sickle Cell Trait and . Clin J Am Soc Nephrol. 2020;16(2):287-289doi: 10.2215/CJN.12100720.
Reiner, A. P., Raffield, L. M., Franceschini, N., Auer, P. L., Lange, E. M., Nickerson, D. A., Zakai, N. A., Correa, A., Olson, N. (2021). Effect of Sickle Cell Trait and . Clinical journal of the American Society of Nephrology : CJASN, 16(2), 287-289. https://doi.org/10.2215/CJN.12100720
Reiner, Alexander P, et al. "Effect of Sickle Cell Trait and ." Clinical journal of the American Society of Nephrology : CJASN vol. 16,2 (2021): 287-289. doi: https://doi.org/10.2215/CJN.12100720
Reiner AP, Raffield LM, Franceschini N, Auer PL, Lange EM, Nickerson DA, Zakai NA, Correa A, Olson N. Effect of Sickle Cell Trait and . Clin J Am Soc Nephrol. 2021 Feb 08;16(2):287-289. doi: 10.2215/CJN.12100720. Epub 2020 Dec 02. PMID: 33268503; PMCID: PMC7863645.
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Discovery and fine-mapping of kidney function loci in first genome-wide association study in Africans.

Human molecular genetics

Fatumo S, Chikowore T, Kalyesubula R, Nsubuga RN, Asiki G, Nashiru O, Seeley J, Crampin AC, Nitsch D, Smeeth L, Kaleebu P, Burgess S, Nyirenda M, Franceschini N, Morris AP, Tomlinson L, Newton R.
PMID: 33783510
Hum Mol Genet. 2021 Jul 28;30(16):1559-1568. doi: 10.1093/hmg/ddab088.

Genome-wide association studies (GWAS) of kidney function have uncovered hundreds of loci, primarily in populations of European ancestry. We have undertaken the first continental African GWAS of estimated glomerular filtration rate (eGFR), a measure of kidney function used to...

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Fatumo S, Chikowore T, Kalyesubula R, et al. Discovery and fine-mapping of kidney function loci in first genome-wide association study in Africans. Hum Mol Genet. 2021;30(16):1559-1568doi: 10.1093/hmg/ddab088.
Fatumo, S., Chikowore, T., Kalyesubula, R., Nsubuga, R. N., Asiki, G., Nashiru, O., Seeley, J., Crampin, A. C., Nitsch, D., Smeeth, L., Kaleebu, P., Burgess, S., Nyirenda, M., Franceschini, N., Morris, A. P., Tomlinson, L., & Newton, R. (2021). Discovery and fine-mapping of kidney function loci in first genome-wide association study in Africans. Human molecular genetics, 30(16), 1559-1568. https://doi.org/10.1093/hmg/ddab088
Fatumo, Segun, et al. "Discovery and fine-mapping of kidney function loci in first genome-wide association study in Africans." Human molecular genetics vol. 30,16 (2021): 1559-1568. doi: https://doi.org/10.1093/hmg/ddab088
Fatumo S, Chikowore T, Kalyesubula R, Nsubuga RN, Asiki G, Nashiru O, Seeley J, Crampin AC, Nitsch D, Smeeth L, Kaleebu P, Burgess S, Nyirenda M, Franceschini N, Morris AP, Tomlinson L, Newton R. Discovery and fine-mapping of kidney function loci in first genome-wide association study in Africans. Hum Mol Genet. 2021 Jul 28;30(16):1559-1568. doi: 10.1093/hmg/ddab088. PMID: 33783510; PMCID: PMC8330895.
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Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans.

Human genomics

Guan M, Keaton JM, Dimitrov L, Hicks PJ, Xu J, Palmer ND, Ma L, Das SK, Chen YI, Coresh J, Fornage M, Franceschini N, Kramer H, Langefeld CD, Mychaleckyj JC, Parekh RS, Post WS, Rasmussen-Torvik LJ, Rich SS, Rotter JI, Sedor JR, Thornley-Brown D, Tin A, Wilson JG, Freedman BI, Bowden DW, Ng MCY.
PMID: 31092297
Hum Genomics. 2019 May 15;13(1):21. doi: 10.1186/s40246-019-0205-7.

BACKGROUND: End-stage kidney disease (ESKD) is a significant public health concern disproportionately affecting African Americans (AAs). Type 2 diabetes (T2D) is the leading cause of ESKD in the USA, and efforts to uncover genetic susceptibility to diabetic kidney disease...

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Guan M, Keaton JM, Dimitrov L, et al. Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans. Hum Genomics. 2019;13(1):21doi: 10.1186/s40246-019-0205-7.
Guan, M., Keaton, J. M., Dimitrov, L., Hicks, P. J., Xu, J., Palmer, N. D., Ma, L., Das, S. K., Chen, Y. I., Coresh, J., Fornage, M., Franceschini, N., Kramer, H., Langefeld, C. D., Mychaleckyj, J. C., Parekh, R. S., Post, W. S., Rasmussen-Torvik, L. J., Rich, S. S., Rotter, J. I., Sedor, J. R., Thornley-Brown, D., Tin, A., Wilson, J. G., Freedman, B. I., Bowden, D. W., Ng, M. C. Y. (2019). Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans. Human genomics, 13(1), 21. https://doi.org/10.1186/s40246-019-0205-7
Guan, Meijian, et al. "Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans." Human genomics vol. 13,1 (2019): 21. doi: https://doi.org/10.1186/s40246-019-0205-7
Guan M, Keaton JM, Dimitrov L, Hicks PJ, Xu J, Palmer ND, Ma L, Das SK, Chen YI, Coresh J, Fornage M, Franceschini N, Kramer H, Langefeld CD, Mychaleckyj JC, Parekh RS, Post WS, Rasmussen-Torvik LJ, Rich SS, Rotter JI, Sedor JR, Thornley-Brown D, Tin A, Wilson JG, Freedman BI, Bowden DW, Ng MCY. Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans. Hum Genomics. 2019 May 15;13(1):21. doi: 10.1186/s40246-019-0205-7. PMID: 31092297; PMCID: PMC6521376.
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Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease.

International journal of epidemiology

Zheng J, Zhang Y, Rasheed H, Walker V, Sugawara Y, Li J, Leng Y, Elsworth B, Wootton RE, Fang S, Yang Q, Burgess S, Haycock PC, Borges MC, Cho Y, Carnegie R, Howell A, Robinson J, Thomas LF, Brumpton BM, Hveem K, Hallan S, Franceschini N, Morris AP, Köttgen A, Pattaro C, Wuttke M, Yamamoto M, Kashihara N, Akiyama M, Kanai M, Matsuda K, Kamatani Y, Okada Y, Walters R, Millwood IY, Chen Z, Davey Smith G, Barbour S, Yu C, Åsvold BO, Zhang H, Gaunt TR.
PMID: 34999880
Int J Epidemiol. 2022 Jan 06;50(6):1995-2010. doi: 10.1093/ije/dyab203.

BACKGROUND: This study was to systematically test whether previously reported risk factors for chronic kidney disease (CKD) are causally related to CKD in European and East Asian ancestries using Mendelian randomization.METHODS: A total of 45 risk factors with genetic...

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Zheng J, Zhang Y, Rasheed H, et al. Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease. Int J Epidemiol. 2022;50(6):1995-2010doi: 10.1093/ije/dyab203.
Zheng, J., Zhang, Y., Rasheed, H., Walker, V., Sugawara, Y., Li, J., Leng, Y., Elsworth, B., Wootton, R. E., Fang, S., Yang, Q., Burgess, S., Haycock, P. C., Borges, M. C., Cho, Y., Carnegie, R., Howell, A., Robinson, J., Thomas, L. F., Brumpton, B. M., Hveem, K., Hallan, S., Franceschini, N., Morris, A. P., Köttgen, A., Pattaro, C., Wuttke, M., Yamamoto, M., Kashihara, N., Akiyama, M., Kanai, M., Matsuda, K., Kamatani, Y., Okada, Y., Walters, R., Millwood, I. Y., Chen, Z., Davey Smith, G., Barbour, S., Yu, C., Åsvold, B. O., Zhang, H., & Gaunt, T. R. (2022). Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease. International journal of epidemiology, 50(6), 1995-2010. https://doi.org/10.1093/ije/dyab203
Zheng, Jie, et al. "Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease." International journal of epidemiology vol. 50,6 (2022): 1995-2010. doi: https://doi.org/10.1093/ije/dyab203
Zheng J, Zhang Y, Rasheed H, Walker V, Sugawara Y, Li J, Leng Y, Elsworth B, Wootton RE, Fang S, Yang Q, Burgess S, Haycock PC, Borges MC, Cho Y, Carnegie R, Howell A, Robinson J, Thomas LF, Brumpton BM, Hveem K, Hallan S, Franceschini N, Morris AP, Köttgen A, Pattaro C, Wuttke M, Yamamoto M, Kashihara N, Akiyama M, Kanai M, Matsuda K, Kamatani Y, Okada Y, Walters R, Millwood IY, Chen Z, Davey Smith G, Barbour S, Yu C, Åsvold BO, Zhang H, Gaunt TR. Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease. Int J Epidemiol. 2022 Jan 06;50(6):1995-2010. doi: 10.1093/ije/dyab203. PMID: 34999880; PMCID: PMC8743120.
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Metabolome-wide association study of estimated glomerular filtration rates in Hispanics.

Kidney international

Lin BM, Zhang Y, Yu B, Boerwinkle E, Thygarajan B, Yunes M, Daviglus ML, Qi Q, Kaplan R, Lash J, Cai J, Sofer T, Franceschini N.
PMID: 34774559
Kidney Int. 2022 Jan;101(1):144-151. doi: 10.1016/j.kint.2021.09.032. Epub 2021 Nov 10.

Circulating metabolites are by-products of endogenous metabolism or exogenous sources and may inform disease states. Our study aimed to identify the source of variability in the association of metabolites with estimated glomerular filtration rate (eGFR) in Hispanics/Latinos with low...

Cite
Lin BM, Zhang Y, Yu B, et al. Metabolome-wide association study of estimated glomerular filtration rates in Hispanics. Kidney Int. 2021;101(1):144-151doi: 10.1016/j.kint.2021.09.032.
Lin, B. M., Zhang, Y., Yu, B., Boerwinkle, E., Thygarajan, B., Yunes, M., Daviglus, M. L., Qi, Q., Kaplan, R., Lash, J., Cai, J., Sofer, T., & Franceschini, N. (2022). Metabolome-wide association study of estimated glomerular filtration rates in Hispanics. Kidney international, 101(1), 144-151. https://doi.org/10.1016/j.kint.2021.09.032
Lin, Bridget M, et al. "Metabolome-wide association study of estimated glomerular filtration rates in Hispanics." Kidney international vol. 101,1 (2022): 144-151. doi: https://doi.org/10.1016/j.kint.2021.09.032
Lin BM, Zhang Y, Yu B, Boerwinkle E, Thygarajan B, Yunes M, Daviglus ML, Qi Q, Kaplan R, Lash J, Cai J, Sofer T, Franceschini N. Metabolome-wide association study of estimated glomerular filtration rates in Hispanics. Kidney Int. 2022 Jan;101(1):144-151. doi: 10.1016/j.kint.2021.09.032. Epub 2021 Nov 10. PMID: 34774559; PMCID: PMC8741745.
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Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans.

Human genomics

Guan M, Keaton JM, Dimitrov L, Hicks PJ, Xu J, Palmer ND, Ma L, Das SK, Chen YI, Coresh J, Fornage M, Franceschini N, Kramer H, Langefeld CD, Mychaleckyj JC, Parekh RS, Post WS, Rasmussen-Torvik LJ, Rich SS, Rotter JI, Sedor JR, Thornley-Brown D, Tin A, Wilson JG, Freedman BI, Bowden DW, Ng MCY.
PMID: 31092297
Hum Genomics. 2019 May 15;13(1):21. doi: 10.1186/s40246-019-0205-7.

BACKGROUND: End-stage kidney disease (ESKD) is a significant public health concern disproportionately affecting African Americans (AAs). Type 2 diabetes (T2D) is the leading cause of ESKD in the USA, and efforts to uncover genetic susceptibility to diabetic kidney disease...

Cite
Guan M, Keaton JM, Dimitrov L, et al. Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans. Hum Genomics. 2019;13(1):21doi: 10.1186/s40246-019-0205-7.
Guan, M., Keaton, J. M., Dimitrov, L., Hicks, P. J., Xu, J., Palmer, N. D., Ma, L., Das, S. K., Chen, Y. I., Coresh, J., Fornage, M., Franceschini, N., Kramer, H., Langefeld, C. D., Mychaleckyj, J. C., Parekh, R. S., Post, W. S., Rasmussen-Torvik, L. J., Rich, S. S., Rotter, J. I., Sedor, J. R., Thornley-Brown, D., Tin, A., Wilson, J. G., Freedman, B. I., Bowden, D. W., Ng, M. C. Y. (2019). Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans. Human genomics, 13(1), 21. https://doi.org/10.1186/s40246-019-0205-7
Guan, Meijian, et al. "Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans." Human genomics vol. 13,1 (2019): 21. doi: https://doi.org/10.1186/s40246-019-0205-7
Guan M, Keaton JM, Dimitrov L, Hicks PJ, Xu J, Palmer ND, Ma L, Das SK, Chen YI, Coresh J, Fornage M, Franceschini N, Kramer H, Langefeld CD, Mychaleckyj JC, Parekh RS, Post WS, Rasmussen-Torvik LJ, Rich SS, Rotter JI, Sedor JR, Thornley-Brown D, Tin A, Wilson JG, Freedman BI, Bowden DW, Ng MCY. Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans. Hum Genomics. 2019 May 15;13(1):21. doi: 10.1186/s40246-019-0205-7. PMID: 31092297; PMCID: PMC6521376.
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Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci.

Genome medicine

Breeze CE, Batorsky A, Lee MK, Szeto MD, Xu X, McCartney DL, Jiang R, Patki A, Kramer HJ, Eales JM, Raffield L, Lange L, Lange E, Durda P, Liu Y, Tracy RP, Van Den Berg D, Evans KL, Kraus WE, Shah S, Tiwari HK, Hou L, Whitsel EA, Jiang X, Charchar FJ, Baccarelli AA, Rich SS, Morris AP, Irvin MR, Arnett DK, Hauser ER, Rotter JI, Correa A, Hayward C, Horvath S, Marioni RE, Tomaszewski M, Beck S, Berndt SI, London SJ, Mychaleckyj JC, Franceschini N.
PMID: 33931109
Genome Med. 2021 Apr 30;13(1):74. doi: 10.1186/s13073-021-00877-z.

BACKGROUND: DNA methylation (DNAm) is associated with gene regulation and estimated glomerular filtration rate (eGFR), a measure of kidney function. Decreased eGFR is more common among US Hispanics and African Americans. The causes for this are poorly understood. We...

Cite
Breeze CE, Batorsky A, Lee MK, et al. Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci. Genome Med. 2021;13(1):74doi: 10.1186/s13073-021-00877-z.
Breeze, C. E., Batorsky, A., Lee, M. K., Szeto, M. D., Xu, X., McCartney, D. L., Jiang, R., Patki, A., Kramer, H. J., Eales, J. M., Raffield, L., Lange, L., Lange, E., Durda, P., Liu, Y., Tracy, R. P., Van Den Berg, D., Evans, K. L., Kraus, W. E., Shah, S., Tiwari, H. K., Hou, L., Whitsel, E. A., Jiang, X., Charchar, F. J., Baccarelli, A. A., Rich, S. S., Morris, A. P., Irvin, M. R., Arnett, D. K., Hauser, E. R., Rotter, J. I., Correa, A., Hayward, C., Horvath, S., Marioni, R. E., Tomaszewski, M., Beck, S., Berndt, S. I., London, S. J., Mychaleckyj, J. C., & Franceschini, N. (2021). Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci. Genome medicine, 13(1), 74. https://doi.org/10.1186/s13073-021-00877-z
Breeze, Charles E, et al. "Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci." Genome medicine vol. 13,1 (2021): 74. doi: https://doi.org/10.1186/s13073-021-00877-z
Breeze CE, Batorsky A, Lee MK, Szeto MD, Xu X, McCartney DL, Jiang R, Patki A, Kramer HJ, Eales JM, Raffield L, Lange L, Lange E, Durda P, Liu Y, Tracy RP, Van Den Berg D, Evans KL, Kraus WE, Shah S, Tiwari HK, Hou L, Whitsel EA, Jiang X, Charchar FJ, Baccarelli AA, Rich SS, Morris AP, Irvin MR, Arnett DK, Hauser ER, Rotter JI, Correa A, Hayward C, Horvath S, Marioni RE, Tomaszewski M, Beck S, Berndt SI, London SJ, Mychaleckyj JC, Franceschini N. Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci. Genome Med. 2021 Apr 30;13(1):74. doi: 10.1186/s13073-021-00877-z. PMID: 33931109; PMCID: PMC8088054.
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Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study.

Frontiers in genetics

Lin BM, Nadkarni GN, Tao R, Graff M, Fornage M, Buyske S, Matise TC, Highland HM, Wilkens LR, Carlson CS, Park SL, Setiawan VW, Ambite JL, Heiss G, Boerwinkle E, Lin DY, Morris AP, Loos RJF, Kooperberg C, North KE, Wassel CL, Franceschini N.
PMID: 31178898
Front Genet. 2019 May 24;10:494. doi: 10.3389/fgene.2019.00494. eCollection 2019.

BACKGROUND: Chronic kidney disease (CKD) is common and disproportionally burdens United States ethnic minorities. Its genetic determinants may differ by disease severity and clinical stages. To uncover genetic factors associated CKD severity among high-risk ethnic groups, we performed genome-wide...

Cite
Lin BM, Nadkarni GN, Tao R, et al. Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study. Front Genet. 2019;10:494doi: 10.3389/fgene.2019.00494.
Lin, B. M., Nadkarni, G. N., Tao, R., Graff, M., Fornage, M., Buyske, S., Matise, T. C., Highland, H. M., Wilkens, L. R., Carlson, C. S., Park, S. L., Setiawan, V. W., Ambite, J. L., Heiss, G., Boerwinkle, E., Lin, D. Y., Morris, A. P., Loos, R. J. F., Kooperberg, C., North, K. E., Wassel, C. L., & Franceschini, N. (2019). Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study. Frontiers in genetics, 10494. https://doi.org/10.3389/fgene.2019.00494
Lin, Bridget M, et al. "Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study." Frontiers in genetics vol. 10 (2019): 494. doi: https://doi.org/10.3389/fgene.2019.00494
Lin BM, Nadkarni GN, Tao R, Graff M, Fornage M, Buyske S, Matise TC, Highland HM, Wilkens LR, Carlson CS, Park SL, Setiawan VW, Ambite JL, Heiss G, Boerwinkle E, Lin DY, Morris AP, Loos RJF, Kooperberg C, North KE, Wassel CL, Franceschini N. Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study. Front Genet. 2019 May 24;10:494. doi: 10.3389/fgene.2019.00494. eCollection 2019. PMID: 31178898; PMCID: PMC6544117.
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