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Showing 1 to 10 of 10 entries
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Brain Sexual Differentiation and Requirement of SRY: Why or Why Not?.

Frontiers in neuroscience

Rosenfeld CS.
PMID: 29200993
Front Neurosci. 2017 Nov 16;11:632. doi: 10.3389/fnins.2017.00632. eCollection 2017.

Brain sexual differentiation is orchestrated by precise coordination of sex steroid hormones. In some species, programming of select male brain regions is dependent upon aromatization of testosterone to estrogen. In mammals, these hormones surge during the organizational and activational...

Placental Changes in the serotonin transporter (Slc6a4) knockout mouse suggest a role for serotonin in controlling nutrient acquisition.

Placenta

Mao J, Kinkade JA, Bivens NJ, Roberts RM, Rosenfeld CS.
PMID: 34649169
Placenta. 2021 Nov;115:158-168. doi: 10.1016/j.placenta.2021.09.021. Epub 2021 Oct 01.

INTRODUCTION: The mouse placenta accumulates and possibly produces serotonin (5-hydroxytryptamine; 5-HT) in parietal trophoblast giant cells (pTGC) located at the interface between the placenta and maternal deciduum. However, the roles of 5-HT in placental function are unclear. This lack...

Cognitive Effects of Aromatase and Possible Role in Memory Disorders.

Frontiers in endocrinology

Rosenfeld CS, Shay DA, Vieira-Potter VJ.
PMID: 30386297
Front Endocrinol (Lausanne). 2018 Oct 17;9:610. doi: 10.3389/fendo.2018.00610. eCollection 2018.

Diverse cognitive functions in many vertebrate species are influenced by local conversion of androgens to 17β-estradiol (E2) by aromatase. This enzyme is highly expressed in various brain regions across species, with some inter-species variation in terms of regional brain...

Maternal vitamin D deficiency and developmental origins of health and disease (DOHaD).

The Journal of endocrinology

Ideraabdullah FY, Belenchia AM, Rosenfeld CS, Kullman SW, Knuth M, Mahapatra D, Bereman M, Levin ED, Peterson CA.
PMID: 30909167
J Endocrinol. 2019 Mar 01; doi: 10.1530/JOE-18-0541. Epub 2019 Mar 01.

Vitamin D is an essential nutrient that is metabolized in the body to generate an active metabolite (1,25(OH)2D) with hormone-like activity and highly diverse roles in cellular function. Vitamin D deficiency (VDD) is a prevalent but easily preventable nutritional...

miRNA changes in the mouse placenta due to bisphenol A exposure.

Epigenomics

Mao J, Kinkade JA, Bivens NJ, Rosenfeld CS.
PMID: 34841895
Epigenomics. 2021 Dec;13(24):1909-1919. doi: 10.2217/epi-2021-0339. Epub 2021 Nov 29.

No abstract available.

Nontargeted fecal metabolomics: an emerging tool to probe the role of the gut microbiome in host health.

Bioanalysis

Sarma SJ, Lei Z, Rosenfeld CS, Ericsson A, Sumner LW.
PMID: 32209031
Bioanalysis. 2020 Mar;12(6):351-353. doi: 10.4155/bio-2020-0010. Epub 2020 Mar 25.

No abstract available.

Xenoestrogen Effects on the Gut Microbiome.

Current opinion in endocrine and metabolic research

Rosenfeld CS.
PMID: 34423175
Curr Opin Endocr Metab Res. 2021 Aug;19:41-45. doi: 10.1016/j.coemr.2021.05.006. Epub 2021 Jun 06.

Endocrine disrupting chemicals (EDCs) that act as xenoestrogens are natural and synthetic chemicals widely present in food products, industrial products, and the environment. Such compounds can activate or inhibit normal hormonal pathways by binding to steroid and non-steroid receptors....

The Roles of the Histone Protein Modifier EZH2 in the Uterus and Placenta.

Epigenomes

Mesa AM, Rosenfeld CS, Tuteja G, Medrano TI, Cooke PS.
PMID: 33732505
Epigenomes. 2020 Sep;4(3). doi: 10.3390/epigenomes4030020. Epub 2020 Sep 02.

Epigenetic modifications regulate normal physiological, as well as pathological processes in various organs, including the uterus and placenta. Both organs undergo dramatic and rapid restructuring that depends upon precise orchestration of events. Epigenetic changes that alter transcription and translation...

Hypothalamic gene expression changes in F.

Heliyon

Johnson SA, Ellersieck MR, Rosenfeld CS.
PMID: 30003164
Heliyon. 2018 Jun 29;4(6):e00672. doi: 10.1016/j.heliyon.2018.e00672. eCollection 2018 Jun.

Bisphenol A (BPA) is a pervasive industrial chemical used in many common household items. To examine how early exposure to BPA and ethinyl estradiol (EE, estrogen in birth control pill) might affect biparental care, effects of these chemicals in...

Sexually Dimorphic Effects of Aromatase on Neurobehavioral Responses.

Frontiers in molecular neuroscience

Shay DA, Vieira-Potter VJ, Rosenfeld CS.
PMID: 30374289
Front Mol Neurosci. 2018 Oct 15;11:374. doi: 10.3389/fnmol.2018.00374. eCollection 2018.

Aromatase is the enzyme responsible for converting testosterone to estradiol. In mammals, aromatase is expressed in the testes, ovaries, brain, and other tissues. While estrogen is traditionally associated with reproduction and sexual behavior in females, our current understanding broadens...

Showing 1 to 10 of 10 entries