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Showing 1 to 5 of 5 entries
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ZO-1 associates with α3 integrin and connexin43 in trabecular meshwork and Schlemm's canal cells.

International journal of physiology, pathophysiology and pharmacology

Li X, Acott TS, Nagy JI, Kelley MJ.
PMID: 32211117
Int J Physiol Pathophysiol Pharmacol. 2020 Feb 25;12(1):1-10. eCollection 2020.

Cellular structures that perform essential homeostatic functions include tight junctions, gap junctions, desmosomes and adherens junctions. The aqueous humor, produced by the ciliary body, passes into the anterior chamber of the eye and is filtered by the trabecular meshwork...

Normal and glaucomatous outflow regulation.

Progress in retinal and eye research

Acott TS, Vranka JA, Keller KE, Raghunathan V, Kelley MJ.
PMID: 32795516
Prog Retin Eye Res. 2021 May;82:100897. doi: 10.1016/j.preteyeres.2020.100897. Epub 2020 Aug 11.

Glaucoma remains only partially understood, particularly at the level of intraocular pressure (IOP) regulation. Trabecular meshwork (TM) and Schlemm's canal inner wall endothelium (SCE) are key to IOP regulation and their characteristics and behavior are the focus of much...

The Trabecular Meshwork: A Basic Review of Form and Function.

Journal of ocular biology

Abu-Hassan DW, Acott TS, Kelley MJ.
PMID: 25356439
J Ocul Biol. 2014 May;2(1). doi: 10.13188/2334-2838.1000017.

No abstract available.

The Juxtacanalicular Region of Ocular Trabecular Meshwork: A Tissue with a Unique Extracellular Matrix and Specialized Function.

Journal of ocular biology

Keller KE, Acott TS.
PMID: 24364042
J Ocul Biol. 2013 Jun;1(1):3.

The trabecular meshwork (TM) is a filter-like tissue located in the anterior segment of the eye. It is composed of a series of fenestrated beams through which aqueous humor flows to exit the anterior chamber via Schlemm's canal. The...

Gap junction connexin43 is a key element in mediating phagocytosis activity in human trabecular meshwork cells.

International journal of physiology, pathophysiology and pharmacology

Li X, Nagy JI, Li D, Acott TS, Kelley MJ.
PMID: 32211119
Int J Physiol Pathophysiol Pharmacol. 2020 Feb 25;12(1):25-31. eCollection 2020.

Human trabecular meshwork (TM) cells play pivotal roles in maintaining homeostasis of intraocular pressure via regulation of aqueous humor outflow. These cells are capable of phagocytosis, which is considered to be essential for their regulatory function. In addition, there...

Showing 1 to 5 of 5 entries