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Bio-protocol

Tracy C, Krämer H.
PMID: 28752110
Bio Protoc. 2017 May 05;7(9). doi: 10.21769/BioProtoc.2256.

Following septic insults, healthy insects, just like vertebrates, mount a complex immune response to contain and destroy pathogens. The failure to efficiently clear bacterial infections in immuno-compromised fly mutants leads to higher mortality rates which provide a powerful indicator...

Drosophila melanogaster cellular repressor of E1A-stimulated genes is a lysosomal protein essential for fly development.

Biochimica et biophysica acta

Kowalewski-Nimmerfall E, Schähs P, Maresch D, Rendic D, Krämer H, Mach L.
PMID: 25173815
Biochim Biophys Acta. 2014 Dec;1843(12):2900-12. doi: 10.1016/j.bbamcr.2014.08.012. Epub 2014 Aug 27.

Mammalian cellular repressor of E1A-stimulated genes is a lysosomal glycoprotein implicated in cellular growth and differentiation. The genome of the fruit fly Drosophila melanogaster encodes a putative orthologue (dCREG), suggesting evolutionarily conserved physiological functions of this protein. In D....

Activated Acinus boosts basal autophagy.

Molecular & cellular oncology

Nandi N, Tyra LK, Krämer H.
PMID: 27308482
Mol Cell Oncol. 2015 Jan 23;2(3):e995043. doi: 10.4161/23723556.2014.995043. eCollection 2015.

Acinus (Acn) is a nuclear protein that participates in the regulation of autophagy. Loss of Acn function prevents autophagy in starving cells. Conversely, Acn activation induces basal autophagy. This enhances the quality control functions of autophagy such as the...

Isolation and Infection of .

Bio-protocol

Tracy C, Krämer H.
PMID: 28758141
Bio Protoc. 2017 Jun 05;7(11). doi: 10.21769/BioProtoc.2300.

Phagocytosis of invading pathogens and their subsequent clearance in lysosomes is important for organismal fitness. We have devised the following protocol to extract phagocytic hemocytes from wild-type and mutant

Showing 1 to 4 of 4 entries