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Functional expansion of the tRNA world under stress.

Molecular cell

Yang XL, Schimmel P.
PMID: 21855789
Mol Cell. 2011 Aug 19;43(4):500-2. doi: 10.1016/j.molcel.2011.08.004.

No abstract available.

Serum-circulating His-tRNA synthetase inhibits organ-targeted immune responses.

Cellular & molecular immunology

Adams RA, Fernandes-Cerqueira C, Notarnicola A, Mertsching E, Xu Z, Lo WS, Ogilvie K, Chiang KP, Ampudia J, Rosengren S, Cubitt A, King DJ, Mendlein JD, Yang XL, Nangle LA, Lundberg IE, Jakobsson PJ, Schimmel P.
PMID: 31797905
Cell Mol Immunol. 2021 Jun;18(6):1463-1475. doi: 10.1038/s41423-019-0331-0. Epub 2019 Dec 04.

His-tRNA synthetase (HARS) is targeted by autoantibodies in chronic and acute inflammatory anti-Jo-1-positive antisynthetase syndrome. The extensive activation and migration of immune cells into lung and muscle are associated with interstitial lung disease, myositis, and morbidity. It is unknown...

Showing 1 to 2 of 2 entries