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Cardiac metabolic effects of K.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Smith CO, Wang YT, Nadtochiy SM, Miller JH, Jonas EA, Dirksen RT, Nehrke K, Brookes PS.
PMID: 29863912
FASEB J. 2018 Jun 04;fj201800139R. doi: 10.1096/fj.201800139R. Epub 2018 Jun 04.

Controversy surrounds the molecular identity of mitochondrial K

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Smith CO, Wang YT, Nadtochiy SM, et al. Cardiac metabolic effects of K. FASEB J. 2018;fj201800139Rdoi: 10.1096/fj.201800139R.
Smith, C. O., Wang, Y. T., Nadtochiy, S. M., Miller, J. H., Jonas, E. A., Dirksen, R. T., Nehrke, K., & Brookes, P. S. (2018). Cardiac metabolic effects of K. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, fj201800139R. https://doi.org/10.1096/fj.201800139R
Smith, Charles O, et al. "Cardiac metabolic effects of K." FASEB journal : official publication of the Federation of American Societies for Experimental Biology vol. (2018): fj201800139R. doi: https://doi.org/10.1096/fj.201800139R
Smith CO, Wang YT, Nadtochiy SM, Miller JH, Jonas EA, Dirksen RT, Nehrke K, Brookes PS. Cardiac metabolic effects of K. FASEB J. 2018 Jun 04;fj201800139R. doi: 10.1096/fj.201800139R. Epub 2018 Jun 04. PMID: 29863912; PMCID: PMC6181635.
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Discovery of Halogenated Benzothiadiazine Derivatives with Anticancer Activity*.

ChemMedChem

Huwaimel BI, Bhakta M, Kulkarni CA, Milliken AS, Wang F, Peng A, Brookes PS, Trippier PC.
PMID: 33331124
ChemMedChem. 2021 Apr 08;16(7):1143-1162. doi: 10.1002/cmdc.202000729. Epub 2021 Jan 26.

Mitochondrial respiratory complex II (CII), also known as succinate dehydrogenase, plays a critical role in mitochondrial metabolism. Known but low potency CII inhibitors are selectively cytotoxic to cancer cells including the benzothiadiazine-based anti-hypoglycemic diazoxide. Herein, we study the structure-activity...

Cite
Huwaimel BI, Bhakta M, Kulkarni CA, et al. Discovery of Halogenated Benzothiadiazine Derivatives with Anticancer Activity*. ChemMedChem. 2021;16(7):1143-1162doi: 10.1002/cmdc.202000729.
Huwaimel, B. I., Bhakta, M., Kulkarni, C. A., Milliken, A. S., Wang, F., Peng, A., Brookes, P. S., & Trippier, P. C. (2021). Discovery of Halogenated Benzothiadiazine Derivatives with Anticancer Activity*. ChemMedChem, 16(7), 1143-1162. https://doi.org/10.1002/cmdc.202000729
Huwaimel, Bader I, et al. "Discovery of Halogenated Benzothiadiazine Derivatives with Anticancer Activity*." ChemMedChem vol. 16,7 (2021): 1143-1162. doi: https://doi.org/10.1002/cmdc.202000729
Huwaimel BI, Bhakta M, Kulkarni CA, Milliken AS, Wang F, Peng A, Brookes PS, Trippier PC. Discovery of Halogenated Benzothiadiazine Derivatives with Anticancer Activity*. ChemMedChem. 2021 Apr 08;16(7):1143-1162. doi: 10.1002/cmdc.202000729. Epub 2021 Jan 26. PMID: 33331124; PMCID: PMC8035258.
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A non-cardiomyocyte autonomous mechanism of cardioprotection involving the SLO1 BK channel.

PeerJ

Wojtovich AP, Nadtochiy SM, Urciuoli WR, Smith CO, Grunnet M, Nehrke K, Brookes PS.
PMID: 23638385
PeerJ. 2013 Mar 05;1:e48. doi: 10.7717/peerj.48. Print 2013.

Opening of BK-type Ca(2+) activated K(+) channels protects the heart against ischemia-reperfusion (IR) injury. However, the location of BK channels responsible for cardioprotection is debated. Herein we confirmed that openers of the SLO1 BK channel, NS1619 and NS11021, were...

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Wojtovich AP, Nadtochiy SM, Urciuoli WR, et al. A non-cardiomyocyte autonomous mechanism of cardioprotection involving the SLO1 BK channel. PeerJ. 2013;1:e48doi: 10.7717/peerj.48.
Wojtovich, A. P., Nadtochiy, S. M., Urciuoli, W. R., Smith, C. O., Grunnet, M., Nehrke, K., & Brookes, P. S. (2013). A non-cardiomyocyte autonomous mechanism of cardioprotection involving the SLO1 BK channel. PeerJ, 1e48. https://doi.org/10.7717/peerj.48
Wojtovich, Andrew P, et al. "A non-cardiomyocyte autonomous mechanism of cardioprotection involving the SLO1 BK channel." PeerJ vol. 1 (2013): e48. doi: https://doi.org/10.7717/peerj.48
Wojtovich AP, Nadtochiy SM, Urciuoli WR, Smith CO, Grunnet M, Nehrke K, Brookes PS. A non-cardiomyocyte autonomous mechanism of cardioprotection involving the SLO1 BK channel. PeerJ. 2013 Mar 05;1:e48. doi: 10.7717/peerj.48. Print 2013. PMID: 23638385; PMCID: PMC3628382.
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FNDC-1-mediated mitophagy and ATFS-1 coordinate to protect against hypoxia-reoxygenation.

Autophagy

Lim Y, Berry B, Viteri S, McCall M, Park EC, Rongo C, Brookes PS, Nehrke K.
PMID: 33416042
Autophagy. 2021 Nov;17(11):3389-3401. doi: 10.1080/15548627.2021.1872885. Epub 2021 Jan 19.

Mitochondrial quality control (MQC) balances organelle adaptation and elimination, and mechanistic crosstalk between the underlying molecular processes affects subsequent stress outcomes. FUNDC1 (FUN14 domain containing 1) is a mammalian mitophagy receptor that responds to hypoxia-reoxygenation (HR) stress. Here, we...

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Lim Y, Berry B, Viteri S, et al. FNDC-1-mediated mitophagy and ATFS-1 coordinate to protect against hypoxia-reoxygenation. Autophagy. 2021;17(11):3389-3401doi: 10.1080/15548627.2021.1872885.
Lim, Y., Berry, B., Viteri, S., McCall, M., Park, E. C., Rongo, C., Brookes, P. S., & Nehrke, K. (2021). FNDC-1-mediated mitophagy and ATFS-1 coordinate to protect against hypoxia-reoxygenation. Autophagy, 17(11), 3389-3401. https://doi.org/10.1080/15548627.2021.1872885
Lim, Yunki, et al. "FNDC-1-mediated mitophagy and ATFS-1 coordinate to protect against hypoxia-reoxygenation." Autophagy vol. 17,11 (2021): 3389-3401. doi: https://doi.org/10.1080/15548627.2021.1872885
Lim Y, Berry B, Viteri S, McCall M, Park EC, Rongo C, Brookes PS, Nehrke K. FNDC-1-mediated mitophagy and ATFS-1 coordinate to protect against hypoxia-reoxygenation. Autophagy. 2021 Nov;17(11):3389-3401. doi: 10.1080/15548627.2021.1872885. Epub 2021 Jan 19. PMID: 33416042; PMCID: PMC8632273.
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Showing 1 to 4 of 4 entries