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Distal Extent of Surgery for Acute Type A Aortic Dissection.

Operative techniques in thoracic and cardiovascular surgery : a comparative atlas : an official publication of the American Association for Thoracic Surgery

Dufendach KA, Sultan I, Gleason TG.
PMID: 33911986
Oper Tech Thorac Cardiovasc Surg. 2019;24(2):82-102. doi: 10.1053/j.optechstcvs.2019.06.002. Epub 2019 Jul 08.

Acute type A aortic dissection (TAAD) is a complex disease associated with extremely high morbidity and mortality for which we advocate a coordinated, protocol-driven system of care delivery that begins at patient diagnosis and continues throughout and beyond aortic...

Common deletion variants causing protocadherin-α deficiency contribute to the complex genetics of BAV and left-sided congenital heart disease.

HGG advances

Teekakirikul P, Zhu W, Gabriel GC, Young CB, Williams K, Martin LJ, Hill JC, Richards T, Billaud M, Phillippi JA, Wang J, Wu Y, Tan T, Devine W, Lin JH, Bais AS, Klonowski J, de Bellaing AM, Saini A, Wang MX, Emerel L, Salamacha N, Wyman SK, Lee C, Sing Li H, Miron A, Zhang J, Xing J, McNamara DM, Fung E, Kirshbom P, Mahle W, Kochilas LK, He Y, Garg V, White P, McBride KL, Benson DW, Gleason TG, Mital S, Lo CW.
PMID: 34888534
HGG Adv. 2021 Jul 08;2(3). doi: 10.1016/j.xhgg.2021.100037. Epub 2021 Jul 29.

Bicuspid aortic valve (BAV) with ~1%-2% prevalence is the most common congenital heart defect (CHD). It frequently results in valve disease and aorta dilation and is a major cause of adult cardiac surgery. BAV is genetically linked to rare...

Medial Hypoxia and Adventitial Vasa Vasorum Remodeling in Human Ascending Aortic Aneurysm.

Frontiers in cardiovascular medicine

Billaud M, Hill JC, Richards TD, Gleason TG, Phillippi JA.
PMID: 30276199
Front Cardiovasc Med. 2018 Sep 17;5:124. doi: 10.3389/fcvm.2018.00124. eCollection 2018.

Human ascending aortic aneurysms characteristically exhibit cystic medial degeneration of the aortic wall encompassing elastin degeneration, proteoglycan accumulation and smooth muscle cell loss. Most studies have focused on the aortic media and there is a limited understanding of the...

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