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Showing 1 to 4 of 4 entries
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Transfusion-independent β(0)-thalassemia after bone marrow transplantation failure: proposed involvement of high parental HbF and an epigenetic mechanism.

American journal of blood research

Paciaroni K, Lucarelli G, Martelli F, Migliaccio AR, von Lindern M, Borg J, Gillemans N, van Dijk TB, Philipsen S.
PMID: 25232502
Am J Blood Res. 2014 Sep 05;4(1):27-32. eCollection 2014.

Currently, bone marrow transplantation is the only curative treatment for β-thalassemia and sickle cell disease. In rare cases, sustained and full fetal hemoglobin production was observed in patients after failure of bone marrow transplantation. This rendered the patients transfusion-free,...

Getting personal with B19 parvovirus.

Blood

Migliaccio G, Migliaccio AR.
PMID: 20133475
Blood. 2010 Feb 04;115(5):922-3. doi: 10.1182/blood-2009-11-252593.

No abstract available.

The role of glucocorticoid receptor (GR) polymorphisms in human erythropoiesis.

American journal of blood research

Varricchio L, Migliaccio AR.
PMID: 25755906
Am J Blood Res. 2014 Dec 15;4(2):53-72. eCollection 2014.

Glucocorticoids are endogenous steroid hormones that regulate several biological functions including proliferation, differentiation and apoptosis in numerous cell types in response to stress. Synthetic glucocorticoids, such as dexamethasone (Dex) are used to treat a variety of diseases ranging from...

Stem cell-derived erythrocytes as upcoming players in blood transfusion.

ISBT science series

Migliaccio AR.
PMID: 26229549
ISBT Sci Ser. 2013 Jun;8(1):165-171. doi: 10.1111/voxs.12048.

BACKGROUND: Blood transfusion is current standard-of-care for genetic forms of anemia that would be otherwise lethal and allows implementation of aggressive cytotoxic/surgical therapies developed for numerous types of cancer. In developed countries the blood supply is adequate and sporadically...

Showing 1 to 4 of 4 entries