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Genome-wide association study of coronary artery disease among individuals with diabetes: the UK Biobank.

Diabetologia

Fall T, Gustafsson S, Orho-Melander M, Ingelsson E.
PMID: 30003307
Diabetologia. 2018 Oct;61(10):2174-2179. doi: 10.1007/s00125-018-4686-z. Epub 2018 Jul 12.

AIMS/HYPOTHESIS: Coronary artery disease (CAD) is a common complication among individuals with diabetes. A better understanding of the genetic background of CAD in this population has the potential to suggest novel molecular targets for screening, risk assessment and drug...

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Fall T, Gustafsson S, Orho-Melander M, et al. Genome-wide association study of coronary artery disease among individuals with diabetes: the UK Biobank. Diabetologia. 2018;61(10):2174-2179doi: 10.1007/s00125-018-4686-z.
Fall, T., Gustafsson, S., Orho-Melander, M., & Ingelsson, E. (2018). Genome-wide association study of coronary artery disease among individuals with diabetes: the UK Biobank. Diabetologia, 61(10), 2174-2179. https://doi.org/10.1007/s00125-018-4686-z
Fall, Tove, et al. "Genome-wide association study of coronary artery disease among individuals with diabetes: the UK Biobank." Diabetologia vol. 61,10 (2018): 2174-2179. doi: https://doi.org/10.1007/s00125-018-4686-z
Fall T, Gustafsson S, Orho-Melander M, Ingelsson E. Genome-wide association study of coronary artery disease among individuals with diabetes: the UK Biobank. Diabetologia. 2018 Oct;61(10):2174-2179. doi: 10.1007/s00125-018-4686-z. Epub 2018 Jul 12. PMID: 30003307; PMCID: PMC6133153.
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Alcohol use and cardiometabolic risk in the UK Biobank: A Mendelian randomization study.

PloS one

Lankester J, Zanetti D, Ingelsson E, Assimes TL.
PMID: 34379647
PLoS One. 2021 Aug 11;16(8):e0255801. doi: 10.1371/journal.pone.0255801. eCollection 2021.

Observational studies suggest alcohol use promotes the development of some adverse cardiometabolic traits but protects against others including outcomes related to coronary artery disease. We used Mendelian randomization (MR) to explore causal relationships between the degree of alcohol consumption...

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Lankester J, Zanetti D, Ingelsson E, et al. Alcohol use and cardiometabolic risk in the UK Biobank: A Mendelian randomization study. PLoS One. 2021;16(8):e0255801doi: 10.1371/journal.pone.0255801.
Lankester, J., Zanetti, D., Ingelsson, E., & Assimes, T. L. (2021). Alcohol use and cardiometabolic risk in the UK Biobank: A Mendelian randomization study. PloS one, 16(8), e0255801. https://doi.org/10.1371/journal.pone.0255801
Lankester, Joanna, et al. "Alcohol use and cardiometabolic risk in the UK Biobank: A Mendelian randomization study." PloS one vol. 16,8 (2021): e0255801. doi: https://doi.org/10.1371/journal.pone.0255801
Lankester J, Zanetti D, Ingelsson E, Assimes TL. Alcohol use and cardiometabolic risk in the UK Biobank: A Mendelian randomization study. PLoS One. 2021 Aug 11;16(8):e0255801. doi: 10.1371/journal.pone.0255801. eCollection 2021. PMID: 34379647; PMCID: PMC8357114.
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Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease.

Cell

de Goede OM, Nachun DC, Ferraro NM, Gloudemans MJ, Rao AS, Smail C, Eulalio TY, Aguet F, Ng B, Xu J, Barbeira AN, Castel SE, Kim-Hellmuth S, Park Y, Scott AJ, Strober BJ, Brown CD, Wen X, Hall IM, Battle A, Lappalainen T, Im HK, Ardlie KG, Mostafavi S, Quertermous T, Kirkegaard K, Montgomery SB.
PMID: 33864768
Cell. 2021 May 13;184(10):2633-2648.e19. doi: 10.1016/j.cell.2021.03.050. Epub 2021 Apr 16.

Long non-coding RNA (lncRNA) genes have well-established and important impacts on molecular and cellular functions. However, among the thousands of lncRNA genes, it is still a major challenge to identify the subset with disease or trait relevance. To systematically...

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de Goede OM, Nachun DC, Ferraro NM, et al. Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease. Cell. 2021;184(10):2633-2648.e19doi: 10.1016/j.cell.2021.03.050.
de Goede, O. M., Nachun, D. C., Ferraro, N. M., Gloudemans, M. J., Rao, A. S., Smail, C., Eulalio, T. Y., Aguet, F., Ng, B., Xu, J., Barbeira, A. N., Castel, S. E., Kim-Hellmuth, S., Park, Y., Scott, A. J., Strober, B. J., Brown, C. D., Wen, X., Hall, I. M., Battle, A., Lappalainen, T., Im, H. K., Ardlie, K. G., Mostafavi, S., Quertermous, T., Kirkegaard, K., & Montgomery, S. B. (2021). Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease. Cell, 184(10), 2633-2648.e19. https://doi.org/10.1016/j.cell.2021.03.050
de Goede, Olivia M, et al. "Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease." Cell vol. 184,10 (2021): 2633-2648.e19. doi: https://doi.org/10.1016/j.cell.2021.03.050
de Goede OM, Nachun DC, Ferraro NM, Gloudemans MJ, Rao AS, Smail C, Eulalio TY, Aguet F, Ng B, Xu J, Barbeira AN, Castel SE, Kim-Hellmuth S, Park Y, Scott AJ, Strober BJ, Brown CD, Wen X, Hall IM, Battle A, Lappalainen T, Im HK, Ardlie KG, Mostafavi S, Quertermous T, Kirkegaard K, Montgomery SB. Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease. Cell. 2021 May 13;184(10):2633-2648.e19. doi: 10.1016/j.cell.2021.03.050. Epub 2021 Apr 16. PMID: 33864768; PMCID: PMC8651477.
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Human Genetics of Obesity and Type 2 Diabetes Mellitus: Past, Present, and Future.

Circulation. Genomic and precision medicine

Ingelsson E, McCarthy MI.
PMID: 29899044
Circ Genom Precis Med. 2018 Jun;11(6):e002090. doi: 10.1161/CIRCGEN.118.002090.

Type 2 diabetes mellitus (T2D) and obesity already represent 2 of the most prominent risk factors for cardiovascular disease, and are destined to increase in importance given the global changes in lifestyle. Ten years have passed since the first...

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Ingelsson E, McCarthy MI. Human Genetics of Obesity and Type 2 Diabetes Mellitus: Past, Present, and Future. Circ Genom Precis Med. 2018;11(6):e002090doi: 10.1161/CIRCGEN.118.002090.
Ingelsson, E., & McCarthy, M. I. (2018). Human Genetics of Obesity and Type 2 Diabetes Mellitus: Past, Present, and Future. Circulation. Genomic and precision medicine, 11(6), e002090. https://doi.org/10.1161/CIRCGEN.118.002090
Ingelsson, Erik, and McCarthy, Mark I. "Human Genetics of Obesity and Type 2 Diabetes Mellitus: Past, Present, and Future." Circulation. Genomic and precision medicine vol. 11,6 (2018): e002090. doi: https://doi.org/10.1161/CIRCGEN.118.002090
Ingelsson E, McCarthy MI. Human Genetics of Obesity and Type 2 Diabetes Mellitus: Past, Present, and Future. Circ Genom Precis Med. 2018 Jun;11(6):e002090. doi: 10.1161/CIRCGEN.118.002090. PMID: 29899044; PMCID: PMC6405228.
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Showing 1 to 4 of 4 entries