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Good Platelets Gone Bad: The Effects of Trauma Patient Plasma on Healthy Platelet Aggregation.

Shock (Augusta, Ga.)

Fields AT, Matthay ZA, Nunez-Garcia B, Matthay EC, Bainton RJ, Callcut RA, Kornblith LZ.
PMID: 32694397
Shock. 2021 Feb 01;55(2):189-197. doi: 10.1097/SHK.0000000000001622.

BACKGROUND: Altered postinjury platelet behavior is recognized in the pathophysiology of trauma-induced coagulopathy (TIC), but the mechanisms remain largely undefined. Studies suggest that soluble factors released by injury may inhibit signaling pathways and induce structural changes in circulating platelets....

Cite
Fields AT, Matthay ZA, Nunez-Garcia B, et al. Good Platelets Gone Bad: The Effects of Trauma Patient Plasma on Healthy Platelet Aggregation. Shock. 2021;55(2):189-197doi: 10.1097/SHK.0000000000001622.
Fields, A. T., Matthay, Z. A., Nunez-Garcia, B., Matthay, E. C., Bainton, R. J., Callcut, R. A., & Kornblith, L. Z. (2021). Good Platelets Gone Bad: The Effects of Trauma Patient Plasma on Healthy Platelet Aggregation. Shock (Augusta, Ga.), 55(2), 189-197. https://doi.org/10.1097/SHK.0000000000001622
Fields, Alexander T, et al. "Good Platelets Gone Bad: The Effects of Trauma Patient Plasma on Healthy Platelet Aggregation." Shock (Augusta, Ga.) vol. 55,2 (2021): 189-197. doi: https://doi.org/10.1097/SHK.0000000000001622
Fields AT, Matthay ZA, Nunez-Garcia B, Matthay EC, Bainton RJ, Callcut RA, Kornblith LZ. Good Platelets Gone Bad: The Effects of Trauma Patient Plasma on Healthy Platelet Aggregation. Shock. 2021 Feb 01;55(2):189-197. doi: 10.1097/SHK.0000000000001622. PMID: 32694397; PMCID: PMC8547718.
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Insights into the association between coagulopathy and inflammation: abnormal clot mechanics are a warning of immunologic dysregulation following major injury.

Annals of translational medicine

Savage SA, Zarzaur BL, Gaski GE, McCarroll T, Zamora R, Namas RA, Vodovotz Y, Callcut RA, Billiar TR, McKinley TO.
PMID: 33437775
Ann Transl Med. 2020 Dec;8(23):1576. doi: 10.21037/atm-20-3651.

BACKGROUND: Severe injury initiates a complex physiologic response encompassing multiple systems and varies phenotypically between patients. Trauma-induced coagulopathy may be an early warning of a poorly coordinated response at the molecular level, including a deleterious immunologic response and worsening...

Cite
Savage SA, Zarzaur BL, Gaski GE, et al. Insights into the association between coagulopathy and inflammation: abnormal clot mechanics are a warning of immunologic dysregulation following major injury. Ann Transl Med. 2020;8(23):1576doi: 10.21037/atm-20-3651.
Savage, S. A., Zarzaur, B. L., Gaski, G. E., McCarroll, T., Zamora, R., Namas, R. A., Vodovotz, Y., Callcut, R. A., Billiar, T. R., & McKinley, T. O. (2020). Insights into the association between coagulopathy and inflammation: abnormal clot mechanics are a warning of immunologic dysregulation following major injury. Annals of translational medicine, 8(23), 1576. https://doi.org/10.21037/atm-20-3651
Savage, Stephanie A, et al. "Insights into the association between coagulopathy and inflammation: abnormal clot mechanics are a warning of immunologic dysregulation following major injury." Annals of translational medicine vol. 8,23 (2020): 1576. doi: https://doi.org/10.21037/atm-20-3651
Savage SA, Zarzaur BL, Gaski GE, McCarroll T, Zamora R, Namas RA, Vodovotz Y, Callcut RA, Billiar TR, McKinley TO. Insights into the association between coagulopathy and inflammation: abnormal clot mechanics are a warning of immunologic dysregulation following major injury. Ann Transl Med. 2020 Dec;8(23):1576. doi: 10.21037/atm-20-3651. PMID: 33437775; PMCID: PMC7791215.
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Showing 1 to 2 of 2 entries