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Life Event Stress and Reduced Cortical Thickness in Youth at Clinical High Risk for Psychosis and Healthy Control Subjects.

Biological psychiatry. Cognitive neuroscience and neuroimaging

Aberizk K, Collins MA, Addington J, Bearden CE, Cadenhead KS, Cornblatt BA, Mathalon DH, McGlashan TH, Perkins DO, Tsuang MT, Woods SW, Cannon TD, Walker EF.
PMID: 33930604
Biol Psychiatry Cogn Neurosci Neuroimaging. 2021 Apr 28; doi: 10.1016/j.bpsc.2021.04.011. Epub 2021 Apr 28.

BACKGROUND: A decline in cortical thickness during early life appears to be a normal neuromaturational process. Accelerated cortical thinning has been linked with conversion to psychosis among individuals at clinical high risk for psychosis (CHR-P). Previous research indicates that...

Childhood trauma and cognitive functioning in individuals at clinical high risk (CHR) for psychosis.

Development and psychopathology

Velikonja T, Velthorst E, Zinberg J, Cannon TD, Cornblatt BA, Perkins DO, Cadenhead KS, Tsuang MT, Addington J, Woods SW, McGlashan T, Mathalon DH, Stone W, Keshavan M, Seidman L, Bearden CE.
PMID: 31959269
Dev Psychopathol. 2021 Feb;33(1):53-64. doi: 10.1017/S095457941900155X.

Evidence suggests that early trauma may have a negative effect on cognitive functioning in individuals with psychosis, yet the relationship between childhood trauma and cognition among those at clinical high risk (CHR) for psychosis remains unexplored. Our sample consisted...

Progress in the Prospective Study of the Schizophrenia Prodrome.

Current psychosis & therapeutics reports

Fu EJ, Cadenhead KS.
PMID: 21691454
Curr Psychos Ther Rep. 2005 Dec 01;3(4):169-174. doi: 10.1007/BF02629450.

Further understanding of the schizophrenia spectrum has helped to define the prodrome of the illness, leading to hopes of earlier identification and intervention in susceptible, at-risk individuals. Given the heterogeneity and comorbidity observed in the clinically and demographically identified...

Schizophrenia spectrum participants have reduced visual contrast sensitivity to chromatic (red/green) and luminance (light/dark) stimuli: new insights into information processing, visual channel function, and antipsychotic effects.

Frontiers in psychology

Cadenhead KS, Dobkins K, McGovern J, Shafer K.
PMID: 23970874
Front Psychol. 2013 Aug 20;4:535. doi: 10.3389/fpsyg.2013.00535. eCollection 2013.

BACKGROUND: Individuals with schizophrenia spectrum diagnoses have deficient visual information processing as assessed by a variety of paradigms including visual backward masking, motion perception and visual contrast sensitivity (VCS). In the present study, the VCS paradigm was used to...

Showing 1 to 4 of 4 entries