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Showing 1 to 12 of 12 entries
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Sex difference of autosomal alleles in populations of European and African descent.

Genes & genomics

Zuo L, Wang T, Lin X, Wang J, Tan Y, Wang X, Yu X, Luo X.
PMID: 26702338
Genes Genomics. 2015 Dec 01;37(12):1007-1016. doi: 10.1007/s13258-015-0332-z. Epub 2015 Sep 03.

In the present study, we aimed to report the individual sex-different genetic markers across autosomes in European- and African-origin populations. A total of 8,400 females and 8,081 males in 19 independent cohorts were genotyped across genomes using Illumina or...

Greater male than female variability in regional brain structure across the lifespan.

Human brain mapping

Wierenga LM, Doucet GE, Dima D, Agartz I, Aghajani M, Akudjedu TN, Albajes-Eizagirre A, Alnaes D, Alpert KI, Andreassen OA, Anticevic A, Asherson P, Banaschewski T, Bargallo N, Baumeister S, Baur-Streubel R, Bertolino A, Bonvino A, Boomsma DI, Borgwardt S, Bourque J, den Braber A, Brandeis D, Breier A, Brodaty H, Brouwer RM, Buitelaar JK, Busatto GF, Calhoun VD, Canales-Rodríguez EJ, Cannon DM, Caseras X, Castellanos FX, Chaim-Avancini TM, Ching CR, Clark VP, Conrod PJ, Conzelmann A, Crivello F, Davey CG, Dickie EW, Ehrlich S, Van't Ent D, Fisher SE, Fouche JP, Franke B, Fuentes-Claramonte P, de Geus EJ, Di Giorgio A, Glahn DC, Gotlib IH, Grabe HJ, Gruber O, Gruner P, Gur RE, Gur RC, Gurholt TP, de Haan L, Haatveit B, Harrison BJ, Hartman CA, Hatton SN, Heslenfeld DJ, van den Heuvel OA, Hickie IB, Hoekstra PJ, Hohmann S, Holmes AJ, Hoogman M, Hosten N, Howells FM, Hulshoff Pol HE, Huyser C, Jahanshad N, James AC, Jiang J, Jönsson EG, Joska JA, Kalnin AJ, Klein M, Koenders L, Kolskår KK, Krämer B, Kuntsi J, Lagopoulos J, Lazaro L, Lebedeva IS, Lee PH, Lochner C, Machielsen MW, Maingault S, Martin NG, Martínez-Zalacaín I, Mataix-Cols D, Mazoyer B, McDonald BC, McDonald C, McIntosh AM, McMahon KL, McPhilemy G, van der Meer D, Menchón JM, Naaijen J, Nyberg L, Oosterlaan J, Paloyelis Y, Pauli P, Pergola G, Pomarol-Clotet E, Portella MJ, Radua J, Reif A, Richard G, Roffman JL, Rosa PG, Sacchet MD, Sachdev PS, Salvador R, Sarró S, Satterthwaite TD, Saykin AJ, Serpa MH, Sim K, Simmons A, Smoller JW, Sommer IE, Soriano-Mas C, Stein DJ, Strike LT, Szeszko PR, Temmingh HS, Thomopoulos SI, Tomyshev AS, Trollor JN, Uhlmann A, Veer IM, Veltman DJ, Voineskos A, Völzke H, Walter H, Wang L, Wang Y, Weber B, Wen W, West JD, Westlye LT, Whalley HC, Williams SC, Wittfeld K, Wolf DH, Wright MJ, Yoncheva YN, Zanetti MV, Ziegler GC, de Zubicaray GI, Thompson PM, Crone EA, Frangou S, Tamnes CK.
PMID: 33044802
Hum Brain Mapp. 2020 Oct 12; doi: 10.1002/hbm.25204. Epub 2020 Oct 12.

For many traits, males show greater variability than females, with possible implications for understanding sex differences in health and disease. Here, the ENIGMA (Enhancing Neuro Imaging Genetics through Meta-Analysis) Consortium presents the largest-ever mega-analysis of sex differences in variability...

Modifiable Arousal in Attention-Deficit/Hyperactivity Disorder and Its Etiological Association With Fluctuating Reaction Times.

Biological psychiatry. Cognitive neuroscience and neuroimaging

James SN, Cheung CHM, Rijsdijk F, Asherson P, Kuntsi J.
PMID: 27840854
Biol Psychiatry Cogn Neurosci Neuroimaging. 2016 Nov;1(6):539-547. doi: 10.1016/j.bpsc.2016.06.003.

BACKGROUND: Cognitive theories of attention-deficit/hyperactivity disorder (ADHD) propose that high within-subject fluctuations of cognitive performance in ADHD, particularly reaction time (RT) variability (RTV), may reflect arousal dysregulation. However, direct evidence of arousal dysregulation and how it may account for...

Maternal serotonin transporter genotype and offsprings' clinical and cognitive measures of ADHD and ASD.

Progress in neuro-psychopharmacology & biological psychiatry

Hanswijk SI, van Rooij D, Oosterlaan J, Luman M, Hoekstra PJ, Hartman CA, Franke B, Sprooten E, Homberg JR, Buitelaar JK.
PMID: 34000292
Prog Neuropsychopharmacol Biol Psychiatry. 2021 Aug 30;110:110354. doi: 10.1016/j.pnpbp.2021.110354. Epub 2021 May 15.

Serotonin (5-HT) is an important factor for prenatal neurodevelopment whereby its neurotrophic actions can be regulated through maternal-fetal interactions. We explored if maternal 5-HTTLPR genotype is associated with clinical and cognitive measures of attention-deficit/hyperactivity disorder (ADHD) and comorbid autism...

Distinct effects of ASD and ADHD symptoms on reward anticipation in participants with ADHD, their unaffected siblings and healthy controls: a cross-sectional study.

Molecular autism

van Dongen EV, von Rhein D, O'Dwyer L, Franke B, Hartman CA, Heslenfeld DJ, Hoekstra PJ, Oosterlaan J, Rommelse N, Buitelaar J.
PMID: 26322219
Mol Autism. 2015 Aug 28;6:48. doi: 10.1186/s13229-015-0043-y. eCollection 2015.

BACKGROUND: Autism spectrum disorder (ASD) traits are continuously distributed throughout the population, and ASD symptoms are also frequently observed in patients with attention-deficit/hyperactivity disorder (ADHD). Both ASD and ADHD have been linked to alterations in reward-related neural processing. However,...

Handling hybrid and missing data in constraint-based causal discovery to study the etiology of ADHD.

International journal of data science and analytics

Sokolova E, von Rhein D, Naaijen J, Groot P, Claassen T, Buitelaar J, Heskes T.
PMID: 28691055
Int J Data Sci Anal. 2017;3(2):105-119. doi: 10.1007/s41060-016-0034-x. Epub 2016 Dec 02.

Causal discovery is an increasingly important method for data analysis in the field of medical research. In this paper, we consider two challenges in causal discovery that occur very often when working with medical data: a mixture of discrete...

Undertreatment of Motor Problems in Children with ADHD.

Child and adolescent mental health

Fliers EA, Franke B, Lambregts-Rommelse NN, Altink ME, Buschgens CJ, Nijhuis-van der Sanden MW, Sergeant JA, Faraone SV, Buitelaar JK.
PMID: 20376200
Child Adolesc Ment Health. 2009 Aug 21;15(2):85-90. doi: 10.1111/j.1475-3588.2009.00538.x.

BACKGROUND: Motor problems occur in 30% to 50% of children with ADHD, and have a severe impact on daily life. In clinical practice there seems to be little attention for this comorbidity with the possible consequence that these motor...

Familiality of Co-existing ADHD and Tic Disorders: Evidence from a Large Sibling Study.

Frontiers in psychology

Roessner V, Banaschewski T, Becker A, Buse J, Wanderer S, Buitelaar JK, Sergeant JA, Sonuga-Barke EJ, Gill M, Manor I, Miranda A, Mulas F, Oades RD, Roeyers H, Steinhausen HC, Faraone SV, Asherson P, Rothenberger A.
PMID: 27486412
Front Psychol. 2016 Jul 19;7:1060. doi: 10.3389/fpsyg.2016.01060. eCollection 2016.

BACKGROUND: The association of attention-deficit/hyperactivity disorder (ADHD) and tic disorder (TD) is frequent and clinically important. Very few and inconclusive attempts have been made to clarify if and how the combination of ADHD+TD runs in families.AIM: To determine the...

The IMAGE project: methodological issues for the molecular genetic analysis of ADHD.

Behavioral and brain functions : BBF

Kuntsi J, Neale BM, Chen W, Faraone SV, Asherson P.
PMID: 16887023
Behav Brain Funct. 2006 Aug 03;2:27. doi: 10.1186/1744-9081-2-27.

The genetic mechanisms involved in attention deficit hyperactivity disorder (ADHD) are being studied with considerable success by several centres worldwide. These studies confirm prior hypotheses about the role of genetic variation within genes involved in the regulation of dopamine,...

The influence of serotonin- and other genes on impulsive behavioral aggression and cognitive impulsivity in children with attention-deficit/hyperactivity disorder (ADHD): Findings from a family-based association test (FBAT) analysis.

Behavioral and brain functions : BBF

Oades RD, Lasky-Su J, Christiansen H, Faraone SV, Sonuga-Barke EJ, Banaschewski T, Chen W, Anney RJ, Buitelaar JK, Ebstein RP, Franke B, Gill M, Miranda A, Roeyers H, Rothenberger A, Sergeant JA, Steinhausen HC, Taylor EA, Thompson M, Asherson P.
PMID: 18937842
Behav Brain Funct. 2008 Oct 20;4:48. doi: 10.1186/1744-9081-4-48.

BACKGROUND: Low serotonergic (5-HT) activity correlates with increased impulsive-aggressive behavior, while the opposite association may apply to cognitive impulsiveness. Both types of impulsivity are associated with attention-deficit/hyperactivity disorder (ADHD), and genes of functional significance for the 5-HT system are...

Attention-Deficit/Hyperactivity Disorder symptoms coincide with altered striatal connectivity.

Biological psychiatry. Cognitive neuroscience and neuroimaging

Oldehinkel M, Beckmann CF, Pruim RH, van Oort ES, Franke B, Hartman CA, Hoekstra PJ, Oosterlaan J, Heslenfeld D, Buitelaar JK, Mennes M.
PMID: 27812554
Biol Psychiatry Cogn Neurosci Neuroimaging. 2016 Jul;1(4):353-363. doi: 10.1016/j.bpsc.2016.03.008. Epub 2016 Apr 13.

BACKGROUND: Cortico-striatal network dysfunction in attention-deficit/hyperactivity disorder (ADHD) is generally investigated by comparing functional connectivity of the main striatal sub-regions (i.e., putamen, caudate, and nucleus accumbens) between an ADHD and a control group. However, dimensional analyses based on continuous...

Consortium neuroscience of attention deficit/hyperactivity disorder and autism spectrum disorder: The ENIGMA adventure.

Human brain mapping

Hoogman M, van Rooij D, Klein M, Boedhoe P, Ilioska I, Li T, Patel Y, Postema MC, Zhang-James Y, Anagnostou E, Arango C, Auzias G, Banaschewski T, Bau CHD, Behrmann M, Bellgrove MA, Brandeis D, Brem S, Busatto GF, Calderoni S, Calvo R, Castellanos FX, Coghill D, Conzelmann A, Daly E, Deruelle C, Dinstein I, Durston S, Ecker C, Ehrlich S, Epstein JN, Fair DA, Fitzgerald J, Freitag CM, Frodl T, Gallagher L, Grevet EH, Haavik J, Hoekstra PJ, Janssen J, Karkashadze G, King JA, Konrad K, Kuntsi J, Lazaro L, Lerch JP, Lesch KP, Louza MR, Luna B, Mattos P, McGrath J, Muratori F, Murphy C, Nigg JT, Oberwelland-Weiss E, O'Gorman Tuura RL, O'Hearn K, Oosterlaan J, Parellada M, Pauli P, Plessen KJ, Ramos-Quiroga JA, Reif A, Reneman L, Retico A, Rosa PGP, Rubia K, Shaw P, Silk TJ, Tamm L, Vilarroya O, Walitza S, Jahanshad N, Faraone SV, Francks C, van den Heuvel OA, Paus T, Thompson PM, Buitelaar JK, Franke B.
PMID: 32420680
Hum Brain Mapp. 2022 Jan;43(1):37-55. doi: 10.1002/hbm.25029. Epub 2020 May 18.

Neuroimaging has been extensively used to study brain structure and function in individuals with attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) over the past decades. Two of the main shortcomings of the neuroimaging literature of these disorders...

Showing 1 to 12 of 12 entries