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A Framework for Understanding the Emerging Role of Corticolimbic-Ventral Striatal Networks in OCD-Associated Repetitive Behaviors.

Frontiers in systems neuroscience

Wood J, Ahmari SE.
PMID: 26733823
Front Syst Neurosci. 2015 Dec 17;9:171. doi: 10.3389/fnsys.2015.00171. eCollection 2015.

Significant interest in the mechanistic underpinnings of obsessive-compulsive disorder (OCD) has fueled research on the neural origins of compulsive behaviors. Converging clinical and preclinical evidence suggests that abnormal repetitive behaviors are driven by dysfunction in cortico-striatal-thalamic-cortical (CSTC) circuits. These...

How can preclinical mouse models be used to gain insight into prefrontal cortex dysfunction in obsessive-compulsive disorder?.

Brain and neuroscience advances

Manning EE, Ahmari SE.
PMID: 32166143
Brain Neurosci Adv. 2018 Jul 04;2:2398212818783896. doi: 10.1177/2398212818783896. eCollection 2018.

Obsessive-compulsive disorder is a debilitating psychiatric disorder that is characterised by perseverative thoughts and behaviours. Cognitive and affective disturbances play a central role in this illness, and it is therefore not surprising that clinical neuroimaging studies have demonstrated widespread...

Using Optogenetics to Dissect the Neural Circuits Underlying OCD and Related Disorders.

Current treatment options in psychiatry

Piantadosi SC, Ahmari SE.
PMID: 31867154
Curr Treat Options Psychiatry. 2015 Sep;2(3):297-311. doi: 10.1007/s40501-015-0056-3. Epub 2015 Jul 15.

No abstract available.

Showing 1 to 3 of 3 entries