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The role of mitophagy in the regulation of mitochondrial energetic status in neurons.

Autophagy

Han S, Zhang M, Jeong YY, Margolis DJ, Cai Q.
PMID: 33757395
Autophagy. 2021 Dec;17(12):4182-4201. doi: 10.1080/15548627.2021.1907167. Epub 2021 Apr 05.

Mitochondria are the main cellular energy powerhouses and supply most of the energy in the form of ATP to fuel essential neuronal functions through oxidative phosphorylation (OXPHOS). In Alzheimer disease (AD), metabolic and mitochondrial disruptions are an early feature...

The role of mitophagy in the regulation of mitochondrial energetic status in neurons.

Autophagy

Han S, Zhang M, Jeong YY, Margolis DJ, Cai Q.
PMID: 33757395
Autophagy. 2021 Dec;17(12):4182-4201. doi: 10.1080/15548627.2021.1907167. Epub 2021 Apr 05.

Mitochondria are the main cellular energy powerhouses and supply most of the energy in the form of ATP to fuel essential neuronal functions through oxidative phosphorylation (OXPHOS). In Alzheimer disease (AD), metabolic and mitochondrial disruptions are an early feature...

Alterations in Mitochondrial Quality Control in Alzheimer's Disease.

Frontiers in cellular neuroscience

Cai Q, Tammineni P.
PMID: 26903809
Front Cell Neurosci. 2016 Feb 09;10:24. doi: 10.3389/fncel.2016.00024. eCollection 2016.

Mitochondrial dysfunction is one of the earliest and most prominent features in the brains of Alzheimer's disease (AD) patients. Recent studies suggest that mitochondrial dysfunction plays a pivotal role in the pathogenesis of AD. Neurons are metabolically active cells,...

Showing 1 to 3 of 3 entries