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Effects of Androgen and Estrogen Receptor Signaling Pathways on Bladder Cancer Initiation and Progression.

Bladder cancer (Amsterdam, Netherlands)

Godoy G, Gakis G, Smith CL, Fahmy O.
PMID: 27376135
Bladder Cancer. 2016 Apr 27;2(2):127-137. doi: 10.3233/BLC-160052.

Epidemiologic studies have long demonstrated clear differences in incidence and progression of bladder cancer between genders suggesting that the mechanisms of development and progression in these tumors have a strong association with steroid hormonal pathways. Such observations led to...

Chemoprevention of BBN-Induced Bladder Carcinogenesis by the Selective Estrogen Receptor Modulator Tamoxifen.

Translational oncology

George SK, Tovar-Sepulveda V, Shen SS, Jian W, Zhang Y, Hilsenbeck SG, Lerner SP, Smith CL.
PMID: 23730403
Transl Oncol. 2013 Jun 01;6(3):244-55. doi: 10.1593/tlo.13247. Print 2013 Jun.

Bladder cancer is the fifth most frequent tumor in men and ninth in women in the United States. Due to a high likelihood of recurrence, effective chemoprevention is a significant unmet need. Estrogen receptors (ERs), primarily ERĪ², are expressed...

Showing 1 to 2 of 2 entries