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Binding and Internalization of Iron Oxide Nanoparticles Targeted to Nuclear Oncoprotein.

Journal of molecular biomarkers & diagnosis

Knight LC, Romano JE, Krynska B, Faro S, Mohamed FB, Gordon J.
PMID: 23487404
J Mol Biomark Diagn. 2010;1(1). doi: 10.4172/2155-9929.1000102.

A targeted nanoconjugate is being developed for non-invasive detection of gene expression in cells expressing the JC virus oncoprotein, T-antigen, which has been associated with medulloblastoma and other cancers. JC virus T-antigen localizes predominantly to the nucleus via a...

Showing 1 to 1 of 1 entries