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Showing 1 to 12 of 23 entries
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Go Girls!-Dance-Based Fitness to Increase Enjoyment of Exercise in Girls at Risk for PCOS.

Children (Basel, Switzerland)

King AK, McGill-Meeks K, Beller JP, Burt Solorzano CM.
PMID: 31500180
Children (Basel). 2019 Sep 06;6(9). doi: 10.3390/children6090099.

Weight loss can reduce the hyperandrogenemia associated with polycystic ovary syndrome (PCOS) in peripubertal girls. Yet, adolescent girls have the lowest rates of physical activity and enjoyment of exercise. We created a dance-based support group (Go Girls!) to entice...

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King AK, McGill-Meeks K, Beller JP, et al. Go Girls!-Dance-Based Fitness to Increase Enjoyment of Exercise in Girls at Risk for PCOS. Children (Basel). 2019;6(9)doi: 10.3390/children6090099.
King, A. K., McGill-Meeks, K., Beller, J. P., & Burt Solorzano, C. M. (2019). Go Girls!-Dance-Based Fitness to Increase Enjoyment of Exercise in Girls at Risk for PCOS. Children (Basel, Switzerland), 6(9), . https://doi.org/10.3390/children6090099
King, Anna K, et al. "Go Girls!-Dance-Based Fitness to Increase Enjoyment of Exercise in Girls at Risk for PCOS." Children (Basel, Switzerland) vol. 6,9 (2019). doi: https://doi.org/10.3390/children6090099
King AK, McGill-Meeks K, Beller JP, Burt Solorzano CM. Go Girls!-Dance-Based Fitness to Increase Enjoyment of Exercise in Girls at Risk for PCOS. Children (Basel). 2019 Sep 06;6(9). doi: 10.3390/children6090099. PMID: 31500180; PMCID: PMC6769571.
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Considerations for Studying Sex as a Biological Variable in Spinal Cord Injury.

Frontiers in neurology

Stewart AN, MacLean SM, Stromberg AJ, Whelan JP, Bailey WM, Gensel JC, Wilson ME.
PMID: 32849242
Front Neurol. 2020 Aug 05;11:802. doi: 10.3389/fneur.2020.00802. eCollection 2020.

In response to NIH initiatives to investigate sex as a biological variable in preclinical animal studies, researchers have increased their focus on male and female differences in neurotrauma. Inclusion of both sexes when modeling neurotrauma is leading to the...

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Stewart AN, MacLean SM, Stromberg AJ, et al. Considerations for Studying Sex as a Biological Variable in Spinal Cord Injury. Front Neurol. 2020;11:802doi: 10.3389/fneur.2020.00802.
Stewart, A. N., MacLean, S. M., Stromberg, A. J., Whelan, J. P., Bailey, W. M., Gensel, J. C., & Wilson, M. E. (2020). Considerations for Studying Sex as a Biological Variable in Spinal Cord Injury. Frontiers in neurology, 11802. https://doi.org/10.3389/fneur.2020.00802
Stewart, Andrew N, et al. "Considerations for Studying Sex as a Biological Variable in Spinal Cord Injury." Frontiers in neurology vol. 11 (2020): 802. doi: https://doi.org/10.3389/fneur.2020.00802
Stewart AN, MacLean SM, Stromberg AJ, Whelan JP, Bailey WM, Gensel JC, Wilson ME. Considerations for Studying Sex as a Biological Variable in Spinal Cord Injury. Front Neurol. 2020 Aug 05;11:802. doi: 10.3389/fneur.2020.00802. eCollection 2020. PMID: 32849242; PMCID: PMC7419700.
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Alterations in Gut Microbiota Do Not Play a Causal Role in Diet-independent Weight Gain Caused by Ovariectomy.

Journal of the Endocrine Society

Sau L, Olmstead CM, Cui LJ, Chen A, Shah RS, Kelley ST, Thackray VG.
PMID: 33324864
J Endocr Soc. 2020 Nov 05;5(1):bvaa173. doi: 10.1210/jendso/bvaa173. eCollection 2021 Jan 01.

Acute estrogen deficiency in women can occur due to many conditions including hyperprolactinemia, chemotherapy, GnRH agonist treatment, and removal of hormone replacement therapy. Ovariectomized (OVX) rodent models, often combined with a high-fat diet (HFD), have been used to investigate...

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Sau L, Olmstead CM, Cui LJ, et al. Alterations in Gut Microbiota Do Not Play a Causal Role in Diet-independent Weight Gain Caused by Ovariectomy. J Endocr Soc. 2020;5(1):bvaa173doi: 10.1210/jendso/bvaa173.
Sau, L., Olmstead, C. M., Cui, L. J., Chen, A., Shah, R. S., Kelley, S. T., & Thackray, V. G. (2021). Alterations in Gut Microbiota Do Not Play a Causal Role in Diet-independent Weight Gain Caused by Ovariectomy. Journal of the Endocrine Society, 5(1), bvaa173. https://doi.org/10.1210/jendso/bvaa173
Sau, Lillian, et al. "Alterations in Gut Microbiota Do Not Play a Causal Role in Diet-independent Weight Gain Caused by Ovariectomy." Journal of the Endocrine Society vol. 5,1 (2021): bvaa173. doi: https://doi.org/10.1210/jendso/bvaa173
Sau L, Olmstead CM, Cui LJ, Chen A, Shah RS, Kelley ST, Thackray VG. Alterations in Gut Microbiota Do Not Play a Causal Role in Diet-independent Weight Gain Caused by Ovariectomy. J Endocr Soc. 2020 Nov 05;5(1):bvaa173. doi: 10.1210/jendso/bvaa173. eCollection 2021 Jan 01. PMID: 33324864; PMCID: PMC7724750.
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Inhibiting Kiss1 Neurons With Kappa Opioid Receptor Agonists to Treat Polycystic Ovary Syndrome and Vasomotor Symptoms.

The Journal of clinical endocrinology and metabolism

McCarthy EA, Dischino D, Maguire C, Leon S, Talbi R, Cheung E, Schteingart CD, Rivière PJM, Reed SD, Steiner RA, Navarro VM.
PMID: 34387319
J Clin Endocrinol Metab. 2022 Jan 01;107(1):e328-e347. doi: 10.1210/clinem/dgab602.

CONTEXT: Recent evidence suggests that vasomotor symptoms (VMS) or hot flashes in the postmenopausal reproductive state and polycystic ovary syndrome (PCOS) in the premenopausal reproductive state emanate from the hyperactivity of Kiss1 neurons in the hypothalamic infundibular/arcuate nucleus (KNDy...

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McCarthy EA, Dischino D, Maguire C, et al. Inhibiting Kiss1 Neurons With Kappa Opioid Receptor Agonists to Treat Polycystic Ovary Syndrome and Vasomotor Symptoms. J Clin Endocrinol Metab. 2022;107(1):e328-e347doi: 10.1210/clinem/dgab602.
McCarthy, E. A., Dischino, D., Maguire, C., Leon, S., Talbi, R., Cheung, E., Schteingart, C. D., Rivière, P. J. M., Reed, S. D., Steiner, R. A., & Navarro, V. M. (2022). Inhibiting Kiss1 Neurons With Kappa Opioid Receptor Agonists to Treat Polycystic Ovary Syndrome and Vasomotor Symptoms. The Journal of clinical endocrinology and metabolism, 107(1), e328-e347. https://doi.org/10.1210/clinem/dgab602
McCarthy, Elizabeth A, et al. "Inhibiting Kiss1 Neurons With Kappa Opioid Receptor Agonists to Treat Polycystic Ovary Syndrome and Vasomotor Symptoms." The Journal of clinical endocrinology and metabolism vol. 107,1 (2022): e328-e347. doi: https://doi.org/10.1210/clinem/dgab602
McCarthy EA, Dischino D, Maguire C, Leon S, Talbi R, Cheung E, Schteingart CD, Rivière PJM, Reed SD, Steiner RA, Navarro VM. Inhibiting Kiss1 Neurons With Kappa Opioid Receptor Agonists to Treat Polycystic Ovary Syndrome and Vasomotor Symptoms. J Clin Endocrinol Metab. 2022 Jan 01;107(1):e328-e347. doi: 10.1210/clinem/dgab602. PMID: 34387319; PMCID: PMC8684497.
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Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis.

Clinical cancer research : an official journal of the American Association for Cancer Research

Wu AML, Gossa S, Samala R, Chung MA, Gril B, Yang HH, Thorsheim HR, Tran AD, Wei D, Taner E, Isanogle K, Yang Y, Dolan EL, Robinson C, Difilippantonio S, Lee MP, Khan I, Smith QR, McGavern DB, Wakefield LM, Steeg PS.
PMID: 34083229
Clin Cancer Res. 2021 Aug 01;27(15):4422-4434. doi: 10.1158/1078-0432.CCR-21-1549. Epub 2021 Jun 03.

PURPOSE: Breast cancer diagnosed in young patients is often aggressive. Because primary breast tumors from young and older patients have similar mutational patterns, we hypothesized that the young host microenvironment promotes more aggressive metastatic disease.EXPERIMENTAL DESIGN: Triple-negative or luminal...

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Wu AML, Gossa S, Samala R, et al. Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis. Clin Cancer Res. 2021;27(15):4422-4434doi: 10.1158/1078-0432.CCR-21-1549.
Wu, A. M. L., Gossa, S., Samala, R., Chung, M. A., Gril, B., Yang, H. H., Thorsheim, H. R., Tran, A. D., Wei, D., Taner, E., Isanogle, K., Yang, Y., Dolan, E. L., Robinson, C., Difilippantonio, S., Lee, M. P., Khan, I., Smith, Q. R., McGavern, D. B., Wakefield, L. M., & Steeg, P. S. (2021). Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis. Clinical cancer research : an official journal of the American Association for Cancer Research, 27(15), 4422-4434. https://doi.org/10.1158/1078-0432.CCR-21-1549
Wu, Alex Man Lai, et al. "Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis." Clinical cancer research : an official journal of the American Association for Cancer Research vol. 27,15 (2021): 4422-4434. doi: https://doi.org/10.1158/1078-0432.CCR-21-1549
Wu AML, Gossa S, Samala R, Chung MA, Gril B, Yang HH, Thorsheim HR, Tran AD, Wei D, Taner E, Isanogle K, Yang Y, Dolan EL, Robinson C, Difilippantonio S, Lee MP, Khan I, Smith QR, McGavern DB, Wakefield LM, Steeg PS. Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis. Clin Cancer Res. 2021 Aug 01;27(15):4422-4434. doi: 10.1158/1078-0432.CCR-21-1549. Epub 2021 Jun 03. PMID: 34083229.
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Effects of spaceflight aboard the International Space Station on mouse estrous cycle and ovarian gene expression.

NPJ microgravity

Hong X, Ratri A, Choi SY, Tash JS, Ronca AE, Alwood JS, Christenson LK.
PMID: 33712627
NPJ Microgravity. 2021 Mar 12;7(1):11. doi: 10.1038/s41526-021-00139-7.

Ovarian steroids dramatically impact normal homeostatic and metabolic processes of most tissues within the body, including muscle, bone, neural, immune, cardiovascular, and reproductive systems. Determining the effects of spaceflight on the ovary and estrous cycle is, therefore, critical to...

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Hong X, Ratri A, Choi SY, et al. Effects of spaceflight aboard the International Space Station on mouse estrous cycle and ovarian gene expression. NPJ Microgravity. 2021;7(1):11doi: 10.1038/s41526-021-00139-7.
Hong, X., Ratri, A., Choi, S. Y., Tash, J. S., Ronca, A. E., Alwood, J. S., & Christenson, L. K. (2021). Effects of spaceflight aboard the International Space Station on mouse estrous cycle and ovarian gene expression. NPJ microgravity, 7(1), 11. https://doi.org/10.1038/s41526-021-00139-7
Hong, Xiaoman, et al. "Effects of spaceflight aboard the International Space Station on mouse estrous cycle and ovarian gene expression." NPJ microgravity vol. 7,1 (2021): 11. doi: https://doi.org/10.1038/s41526-021-00139-7
Hong X, Ratri A, Choi SY, Tash JS, Ronca AE, Alwood JS, Christenson LK. Effects of spaceflight aboard the International Space Station on mouse estrous cycle and ovarian gene expression. NPJ Microgravity. 2021 Mar 12;7(1):11. doi: 10.1038/s41526-021-00139-7. PMID: 33712627; PMCID: PMC7954810.
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Deletion of Gremlin-2 alters estrous cyclicity and disrupts female fertility in mice†.

Biology of reproduction

Rydze RT, Patton BK, Briley SM, Salazar Torralba H, Gipson G, James R, Rajkovic A, Thompson T, Pangas SA.
PMID: 34333627
Biol Reprod. 2021 Nov 15;105(5):1205-1220. doi: 10.1093/biolre/ioab148.

Members of the differential screening-selected gene aberrative in neuroblastoma (DAN) protein family are developmentally conserved extracellular binding proteins that antagonize bone morphogenetic protein (BMP) signaling. This protein family includes the Gremlin proteins, GREM1 and GREM2, which have key functions...

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Rydze RT, Patton BK, Briley SM, et al. Deletion of Gremlin-2 alters estrous cyclicity and disrupts female fertility in mice†. Biol Reprod. 2021;105(5):1205-1220doi: 10.1093/biolre/ioab148.
Rydze, R. T., Patton, B. K., Briley, S. M., Salazar Torralba, H., Gipson, G., James, R., Rajkovic, A., Thompson, T., & Pangas, S. A. (2021). Deletion of Gremlin-2 alters estrous cyclicity and disrupts female fertility in mice†. Biology of reproduction, 105(5), 1205-1220. https://doi.org/10.1093/biolre/ioab148
Rydze, Robert T, et al. "Deletion of Gremlin-2 alters estrous cyclicity and disrupts female fertility in mice†." Biology of reproduction vol. 105,5 (2021): 1205-1220. doi: https://doi.org/10.1093/biolre/ioab148
Rydze RT, Patton BK, Briley SM, Salazar Torralba H, Gipson G, James R, Rajkovic A, Thompson T, Pangas SA. Deletion of Gremlin-2 alters estrous cyclicity and disrupts female fertility in mice†. Biol Reprod. 2021 Nov 15;105(5):1205-1220. doi: 10.1093/biolre/ioab148. PMID: 34333627; PMCID: PMC8599072.
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Progesterone Receptors in AVPV Kisspeptin Neurons Are Sufficient for Positive Feedback Induction of the LH Surge.

Endocrinology

Mohr MA, Esparza LA, Steffen P, Micevych PE, Kauffman AS.
PMID: 34379733
Endocrinology. 2021 Nov 01;162(11). doi: 10.1210/endocr/bqab161.

Kisspeptin, encoded by Kiss1, stimulates gonadotropin-releasing hormone neurons to govern reproduction. In female rodents, estrogen-sensitive kisspeptin neurons in the rostral anteroventral periventricular (AVPV) hypothalamus are thought to mediate estradiol (E2)-induced positive feedback induction of the preovulatory luteinizing hormone (LH)...

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Mohr MA, Esparza LA, Steffen P, et al. Progesterone Receptors in AVPV Kisspeptin Neurons Are Sufficient for Positive Feedback Induction of the LH Surge. Endocrinology. 2021;162(11)doi: 10.1210/endocr/bqab161.
Mohr, M. A., Esparza, L. A., Steffen, P., Micevych, P. E., & Kauffman, A. S. (2021). Progesterone Receptors in AVPV Kisspeptin Neurons Are Sufficient for Positive Feedback Induction of the LH Surge. Endocrinology, 162(11), . https://doi.org/10.1210/endocr/bqab161
Mohr, Margaret A, et al. "Progesterone Receptors in AVPV Kisspeptin Neurons Are Sufficient for Positive Feedback Induction of the LH Surge." Endocrinology vol. 162,11 (2021). doi: https://doi.org/10.1210/endocr/bqab161
Mohr MA, Esparza LA, Steffen P, Micevych PE, Kauffman AS. Progesterone Receptors in AVPV Kisspeptin Neurons Are Sufficient for Positive Feedback Induction of the LH Surge. Endocrinology. 2021 Nov 01;162(11). doi: 10.1210/endocr/bqab161. PMID: 34379733; PMCID: PMC8423423.
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Prenatal exposure to an environmentally relevant phthalate mixture alters ovarian steroidogenesis and folliculogenesis in the F1 generation of adult female mice.

Reproductive toxicology (Elmsford, N.Y.)

Gill S, Brehm E, Leon K, Chiu J, Meling DD, Flaws JA.
PMID: 34597818
Reprod Toxicol. 2021 Dec;106:25-31. doi: 10.1016/j.reprotox.2021.09.013. Epub 2021 Sep 28.

Phthalates are a family of chemicals that can be found in plastic and personal care products used by consumers every day and they are known endocrine disrupting chemicals that can disrupt female reproduction. In previous studies, an environmentally relevant...

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Gill S, Brehm E, Leon K, et al. Prenatal exposure to an environmentally relevant phthalate mixture alters ovarian steroidogenesis and folliculogenesis in the F1 generation of adult female mice. Reprod Toxicol. 2021;106:25-31doi: 10.1016/j.reprotox.2021.09.013.
Gill, S., Brehm, E., Leon, K., Chiu, J., Meling, D. D., & Flaws, J. A. (2021). Prenatal exposure to an environmentally relevant phthalate mixture alters ovarian steroidogenesis and folliculogenesis in the F1 generation of adult female mice. Reproductive toxicology (Elmsford, N.Y.), 10625-31. https://doi.org/10.1016/j.reprotox.2021.09.013
Gill, Sarah, et al. "Prenatal exposure to an environmentally relevant phthalate mixture alters ovarian steroidogenesis and folliculogenesis in the F1 generation of adult female mice." Reproductive toxicology (Elmsford, N.Y.) vol. 106 (2021): 25-31. doi: https://doi.org/10.1016/j.reprotox.2021.09.013
Gill S, Brehm E, Leon K, Chiu J, Meling DD, Flaws JA. Prenatal exposure to an environmentally relevant phthalate mixture alters ovarian steroidogenesis and folliculogenesis in the F1 generation of adult female mice. Reprod Toxicol. 2021 Dec;106:25-31. doi: 10.1016/j.reprotox.2021.09.013. Epub 2021 Sep 28. PMID: 34597818; PMCID: PMC8643306.
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Deletion of Gremlin-2 alters estrous cyclicity and disrupts female fertility in mice†.

Biology of reproduction

Rydze RT, Patton BK, Briley SM, Salazar Torralba H, Gipson G, James R, Rajkovic A, Thompson T, Pangas SA.
PMID: 34333627
Biol Reprod. 2021 Nov 15;105(5):1205-1220. doi: 10.1093/biolre/ioab148.

Members of the differential screening-selected gene aberrative in neuroblastoma (DAN) protein family are developmentally conserved extracellular binding proteins that antagonize bone morphogenetic protein (BMP) signaling. This protein family includes the Gremlin proteins, GREM1 and GREM2, which have key functions...

Cite
Rydze RT, Patton BK, Briley SM, et al. Deletion of Gremlin-2 alters estrous cyclicity and disrupts female fertility in mice†. Biol Reprod. 2021;105(5):1205-1220doi: 10.1093/biolre/ioab148.
Rydze, R. T., Patton, B. K., Briley, S. M., Salazar Torralba, H., Gipson, G., James, R., Rajkovic, A., Thompson, T., & Pangas, S. A. (2021). Deletion of Gremlin-2 alters estrous cyclicity and disrupts female fertility in mice†. Biology of reproduction, 105(5), 1205-1220. https://doi.org/10.1093/biolre/ioab148
Rydze, Robert T, et al. "Deletion of Gremlin-2 alters estrous cyclicity and disrupts female fertility in mice†." Biology of reproduction vol. 105,5 (2021): 1205-1220. doi: https://doi.org/10.1093/biolre/ioab148
Rydze RT, Patton BK, Briley SM, Salazar Torralba H, Gipson G, James R, Rajkovic A, Thompson T, Pangas SA. Deletion of Gremlin-2 alters estrous cyclicity and disrupts female fertility in mice†. Biol Reprod. 2021 Nov 15;105(5):1205-1220. doi: 10.1093/biolre/ioab148. PMID: 34333627; PMCID: PMC8599072.
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The Hippo Pathway Effectors YAP and TAZ Regulate LH Release by Pituitary Gonadotrope Cells in Mice.

Endocrinology

Lalonde-Larue A, Boyer A, Dos Santos EC, Boerboom D, Bernard DJ, Zamberlam G.
PMID: 34905605
Endocrinology. 2022 Jan 01;163(1). doi: 10.1210/endocr/bqab238.

The Hippo transcriptional coactivators YAP and TAZ exert critical roles in morphogenesis, organ size determination and tumorigenesis in many tissues. Although Hippo kinase cascade activity was recently reported in the anterior pituitary gland in mice, the role of the...

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Lalonde-Larue A, Boyer A, Dos Santos EC, et al. The Hippo Pathway Effectors YAP and TAZ Regulate LH Release by Pituitary Gonadotrope Cells in Mice. Endocrinology. 2022;163(1)doi: 10.1210/endocr/bqab238.
Lalonde-Larue, A., Boyer, A., Dos Santos, E. C., Boerboom, D., Bernard, D. J., & Zamberlam, G. (2022). The Hippo Pathway Effectors YAP and TAZ Regulate LH Release by Pituitary Gonadotrope Cells in Mice. Endocrinology, 163(1), . https://doi.org/10.1210/endocr/bqab238
Lalonde-Larue, Ariane, et al. "The Hippo Pathway Effectors YAP and TAZ Regulate LH Release by Pituitary Gonadotrope Cells in Mice." Endocrinology vol. 163,1 (2022). doi: https://doi.org/10.1210/endocr/bqab238
Lalonde-Larue A, Boyer A, Dos Santos EC, Boerboom D, Bernard DJ, Zamberlam G. The Hippo Pathway Effectors YAP and TAZ Regulate LH Release by Pituitary Gonadotrope Cells in Mice. Endocrinology. 2022 Jan 01;163(1). doi: 10.1210/endocr/bqab238. PMID: 34905605; PMCID: PMC8670590.
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Deletion of Gremlin-2 alters estrous cyclicity and disrupts female fertility in mice†.

Biology of reproduction

Rydze RT, Patton BK, Briley SM, Salazar Torralba H, Gipson G, James R, Rajkovic A, Thompson T, Pangas SA.
PMID: 34333627
Biol Reprod. 2021 Nov 15;105(5):1205-1220. doi: 10.1093/biolre/ioab148.

Members of the differential screening-selected gene aberrative in neuroblastoma (DAN) protein family are developmentally conserved extracellular binding proteins that antagonize bone morphogenetic protein (BMP) signaling. This protein family includes the Gremlin proteins, GREM1 and GREM2, which have key functions...

Cite
Rydze RT, Patton BK, Briley SM, et al. Deletion of Gremlin-2 alters estrous cyclicity and disrupts female fertility in mice†. Biol Reprod. 2021;105(5):1205-1220doi: 10.1093/biolre/ioab148.
Rydze, R. T., Patton, B. K., Briley, S. M., Salazar Torralba, H., Gipson, G., James, R., Rajkovic, A., Thompson, T., & Pangas, S. A. (2021). Deletion of Gremlin-2 alters estrous cyclicity and disrupts female fertility in mice†. Biology of reproduction, 105(5), 1205-1220. https://doi.org/10.1093/biolre/ioab148
Rydze, Robert T, et al. "Deletion of Gremlin-2 alters estrous cyclicity and disrupts female fertility in mice†." Biology of reproduction vol. 105,5 (2021): 1205-1220. doi: https://doi.org/10.1093/biolre/ioab148
Rydze RT, Patton BK, Briley SM, Salazar Torralba H, Gipson G, James R, Rajkovic A, Thompson T, Pangas SA. Deletion of Gremlin-2 alters estrous cyclicity and disrupts female fertility in mice†. Biol Reprod. 2021 Nov 15;105(5):1205-1220. doi: 10.1093/biolre/ioab148. PMID: 34333627; PMCID: PMC8599072.
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