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Showing 1 to 12 of 13 entries
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Social Relationships and Health: The Toxic Effects of Perceived Social Isolation.

Social and personality psychology compass

Cacioppo JT, Cacioppo S.
PMID: 24839458
Soc Personal Psychol Compass. 2014 Feb 01;8(2):58-72. doi: 10.1111/spc3.12087.

Research in social epidemiology suggests that the absence of positive social relationships is a significant risk factor for broad-based morbidity and mortality. The nature of these social relationships and the mechanisms underlying this association are of increasing interest as...

Adrenergic-mediated increases in INHBA drive CAF phenotype and collagens.

JCI insight

Nagaraja AS, Dood RL, Armaiz-Pena G, Kang Y, Wu SY, Allen JK, Jennings NB, Mangala LS, Pradeep S, Lyons Y, Haemmerle M, Gharpure KM, Sadaoui NC, Rodriguez-Aguayo C, Ivan C, Wang Y, Baggerly K, Ram P, Lopez-Berestein G, Liu J, Mok SC, Cohen L, Lutgendorf SK, Cole SW, Sood AK.
PMID: 28814667
JCI Insight. 2017 Aug 17;2(16). doi: 10.1172/jci.insight.93076. eCollection 2017 Aug 17.

Adrenergic signaling is known to promote tumor growth and metastasis, but the effects on tumor stroma are not well understood. An unbiased bioinformatics approach analyzing tumor samples from patients with known biobehavioral profiles identified a prominent stromal signature associated...

Selective decision-making deficit in love following damage to the anterior insula.

Current trends in neurology

Cacioppo S, Couto B, Bolmont M, Sedeno L, Frum C, Lewis JW, Manes F, Ibanez A, Cacioppo JT.
PMID: 25382944
Curr Trends Neurol. 2013;7:15-19.

Neuroimaging studies have found a correlation between activation in the anterior insula and love, and a correlation between activation in the posterior insula and lust. The present control-case study describes a neurological male patient, with a rare, circumscribed lesion...

Genetic risk for major depressive disorder and loneliness in sex-specific associations with coronary artery disease.

Molecular psychiatry

Dennis J, Sealock J, Levinson RT, Farber-Eger E, Franco J, Fong S, Straub P, Hucks D, Song WL, Linton MF, Fontanillas P, Elson SL, Ruderfer D, Abdellaoui A, Sanchez-Roige S, Palmer AA, Boomsma DI, Cox NJ, Chen G, Mosley JD, Wells QS, Davis LK.
PMID: 31796895
Mol Psychiatry. 2021 Aug;26(8):4254-4264. doi: 10.1038/s41380-019-0614-y. Epub 2019 Dec 03.

Major depressive disorder (MDD) and loneliness are phenotypically and genetically correlated with coronary artery disease (CAD), but whether these associations are explained by pleiotropic genetic variants or shared comorbidities is unclear. To tease apart these scenarios, we first assessed...

How Can I Connect with Thee: Measuring and Comparing Satisfaction in Multiple Relationship Domains.

Journal of individual psychology (1998)

Hawkley LC, Cacioppo JT.
PMID: 24431985
J Individ Psychol (1998). 2010;66(1):43-58.

Human relationships with people and nonhuman beings were explored in 229 older adults (50-68 yrs old) in the longitudinal Chicago Health, Aging, and Social Relations Study. The Multi-Domain Relationship Satisfaction scale was constructed to pose parallel questions about participants'...

The Emerging Field of Human Social Genomics.

Clinical psychological science : a journal of the Association for Psychological Science

Slavich GM, Cole SW.
PMID: 23853742
Clin Psychol Sci. 2013 Jul;1(3):331-348. doi: 10.1177/2167702613478594.

Although we generally experience our bodies as being biologically stable across time and situations, an emerging field of research is demonstrating that external social conditions, especially our subjective perceptions of those conditions, can influence our most basic internal biological...

Who Sees Human? The Stability and Importance of Individual Differences in Anthropomorphism.

Perspectives on psychological science : a journal of the Association for Psychological Science

Waytz A, Cacioppo J, Epley N.
PMID: 24839457
Perspect Psychol Sci. 2010 May;5(3):219-32. doi: 10.1177/1745691610369336.

Anthropomorphism is a far-reaching phenomenon that incorporates ideas from social psychology, cognitive psychology, developmental psychology, and the neurosciences. Although commonly considered to be a relatively universal phenomenon with only limited importance in modern industrialized societies-more cute than critical-our research...

Thinking About One's Subjective Well-Being: Average Trends and Individual Differences.

Journal of happiness studies

Luhmann M, Hawkley LC, Cacioppo JT.
PMID: 25332682
J Happiness Stud. 2014 Aug 01;15(4):757-781. doi: 10.1007/s10902-013-9448-5.

In two studies, participants reported what they had been thinking about while completing measures of subjective well-being (SWB). These thought reports were analyzed with respect to life domain, valence, and how strongly they were related to actual levels of...

The Phenotype of Loneliness.

The European journal of developmental psychology

Cacioppo JT, Cacioppo S.
PMID: 23024688
Eur J Dev Psychol. 2012 Jul 01;9(4):446-452. doi: 10.1080/17405629.2012.690510. Epub 2012 Jun 29.

Goossens' (in press) review nicely maps the progression of scientific research from its early focus on loneliness as a dysphoric state that results from the discrepancy between a person's ideal and actual social relationships to its current emphasis on...

Depressive-like behavioral response of adult male rhesus monkeys during routine animal husbandry procedure.

Frontiers in behavioral neuroscience

Hennessy MB, McCowan B, Jiang J, Capitanio JP.
PMID: 25249954
Front Behav Neurosci. 2014 Sep 09;8:309. doi: 10.3389/fnbeh.2014.00309. eCollection 2014.

Social isolation is a major risk factor for the development of depressive illness; yet, no practical nonhuman primate model is available for studying processes involved in this effect. In a first study, we noted that adult male rhesus monkeys...

The Population-Based Longitudinal Chicago Health, Aging, and Social Relations Study (CHASRS): Study Description and Predictors of Attrition in Older Adults.

Archives of scientific psychology

Cacioppo JT, Cacioppo S.
PMID: 30221101
Arch Sci Psychol. 2018 Feb;6(1):21-31. doi: 10.1037/arc0000036. Epub 2018 Feb 26.

No abstract available.

Loneliness in monkeys: Neuroimmune mechanisms.

Current opinion in behavioral sciences

Capitanio JP, Cacioppo S, Cole SW.
PMID: 31737750
Curr Opin Behav Sci. 2019 Aug;28:51-57. doi: 10.1016/j.cobeha.2019.01.013. Epub 2019 Feb 28.

Loneliness, or perceived social isolation, may be evident in any group-living species, although its assessment in nonhumans provides some measurement challenges. It is well-known that loneliness in humans confers significant risk for morbidity and mortality, although mechanisms remain unclear....

Showing 1 to 12 of 13 entries