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Showing 1 to 12 of 18 entries
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Partial Androgen Insensitivity Syndrome Presenting with Gynecomastia.

Endocrinology and metabolism (Seoul, Korea)

Lee SW, Kwak DS, Jung IS, Kwak JH, Park JH, Hong SM, Lee CB, Park YS, Kim DS, Choi WH, Ahn YH.
PMID: 25433660
Endocrinol Metab (Seoul). 2015 Jun;30(2):226-30. doi: 10.3803/EnM.2015.30.2.226. Epub 2014 Nov 26.

Gynecomastia is a benign enlargement of the male breast caused by the proliferation of glandular breast tissue. Determining the various causes of gynecomastia such as physiological causes, drugs, systemic diseases, and endocrine disorders is important. Androgen insensitivity syndrome (AIS)...

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Lee SW, Kwak DS, Jung IS, et al. Partial Androgen Insensitivity Syndrome Presenting with Gynecomastia. Endocrinol Metab (Seoul). 2014;30(2):226-30doi: 10.3803/EnM.2015.30.2.226.
Lee, S. W., Kwak, D. S., Jung, I. S., Kwak, J. H., Park, J. H., Hong, S. M., Lee, C. B., Park, Y. S., Kim, D. S., Choi, W. H., & Ahn, Y. H. (2015). Partial Androgen Insensitivity Syndrome Presenting with Gynecomastia. Endocrinology and metabolism (Seoul, Korea), 30(2), 226-30. https://doi.org/10.3803/EnM.2015.30.2.226
Lee, Sung Won, et al. "Partial Androgen Insensitivity Syndrome Presenting with Gynecomastia." Endocrinology and metabolism (Seoul, Korea) vol. 30,2 (2015): 226-30. doi: https://doi.org/10.3803/EnM.2015.30.2.226
Lee SW, Kwak DS, Jung IS, Kwak JH, Park JH, Hong SM, Lee CB, Park YS, Kim DS, Choi WH, Ahn YH. Partial Androgen Insensitivity Syndrome Presenting with Gynecomastia. Endocrinol Metab (Seoul). 2015 Jun;30(2):226-30. doi: 10.3803/EnM.2015.30.2.226. Epub 2014 Nov 26. PMID: 25433660; PMCID: PMC4508269.
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Melatonin up-regulates the expression of the GATA-4 transcription factor and increases testosterone secretion from Leydig cells through RORα signaling in an .

Oncotarget

Deng SL, Zhang Y, Yu K, Wang XX, Chen SR, Han DP, Cheng CY, Lian ZX, Liu YX.
PMID: 29299171
Oncotarget. 2017 Dec 01;8(66):110592-110605. doi: 10.18632/oncotarget.22855. eCollection 2017 Dec 15.

Because androgen function is regulated by its receptors, androgen-androgen receptor signaling is crucial for regulating spermatogenesis. Androgen is mainly testosterone secreted by testis. Based on the results of early studies in goats, the administration of melatonin over an extended...

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Deng SL, Zhang Y, Yu K, et al. Melatonin up-regulates the expression of the GATA-4 transcription factor and increases testosterone secretion from Leydig cells through RORα signaling in an . Oncotarget. 2017;8(66):110592-110605doi: 10.18632/oncotarget.22855.
Deng, S. L., Zhang, Y., Yu, K., Wang, X. X., Chen, S. R., Han, D. P., Cheng, C. Y., Lian, Z. X., & Liu, Y. X. (2017). Melatonin up-regulates the expression of the GATA-4 transcription factor and increases testosterone secretion from Leydig cells through RORα signaling in an . Oncotarget, 8(66), 110592-110605. https://doi.org/10.18632/oncotarget.22855
Deng, Shou-Long, et al. "Melatonin up-regulates the expression of the GATA-4 transcription factor and increases testosterone secretion from Leydig cells through RORα signaling in an ." Oncotarget vol. 8,66 (2017): 110592-110605. doi: https://doi.org/10.18632/oncotarget.22855
Deng SL, Zhang Y, Yu K, Wang XX, Chen SR, Han DP, Cheng CY, Lian ZX, Liu YX. Melatonin up-regulates the expression of the GATA-4 transcription factor and increases testosterone secretion from Leydig cells through RORα signaling in an . Oncotarget. 2017 Dec 01;8(66):110592-110605. doi: 10.18632/oncotarget.22855. eCollection 2017 Dec 15. PMID: 29299171; PMCID: PMC5746406.
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Effect of Korean Herbal Formula (Modified Ojayeonjonghwan) on Androgen Receptor Expression in an Aging Rat Model of Late Onset Hypogonadism.

The world journal of men's health

Choi SW, Jeon SH, Kwon EB, Zhu GQ, Lee KW, Choi JB, Jeong HC, Kim KS, Bae SR, Bae WJ, Kim SJ, Cho HJ, Ha US, Hong SH, Hwang SY, Kim SW.
PMID: 30584994
World J Mens Health. 2019 Jan;37(1):105-112. doi: 10.5534/wjmh.180051.

PURPOSE: Testosterone replacement therapy is an effective treatment for late-onset hypogonadism (LOH) despite a few contraindications and side-effects. The aim of this study was to determine whether modified Ojayeonjonghwan (KH-204, Korean herbal formula) improved LOH. KH-204 is a strong...

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Choi SW, Jeon SH, Kwon EB, et al. Effect of Korean Herbal Formula (Modified Ojayeonjonghwan) on Androgen Receptor Expression in an Aging Rat Model of Late Onset Hypogonadism. World J Mens Health. 2019;37(1):105-112doi: 10.5534/wjmh.180051.
Choi, S. W., Jeon, S. H., Kwon, E. B., Zhu, G. Q., Lee, K. W., Choi, J. B., Jeong, H. C., Kim, K. S., Bae, S. R., Bae, W. J., Kim, S. J., Cho, H. J., Ha, U. S., Hong, S. H., Hwang, S. Y., & Kim, S. W. (2019). Effect of Korean Herbal Formula (Modified Ojayeonjonghwan) on Androgen Receptor Expression in an Aging Rat Model of Late Onset Hypogonadism. The world journal of men's health, 37(1), 105-112. https://doi.org/10.5534/wjmh.180051
Choi, Sae Woong, et al. "Effect of Korean Herbal Formula (Modified Ojayeonjonghwan) on Androgen Receptor Expression in an Aging Rat Model of Late Onset Hypogonadism." The world journal of men's health vol. 37,1 (2019): 105-112. doi: https://doi.org/10.5534/wjmh.180051
Choi SW, Jeon SH, Kwon EB, Zhu GQ, Lee KW, Choi JB, Jeong HC, Kim KS, Bae SR, Bae WJ, Kim SJ, Cho HJ, Ha US, Hong SH, Hwang SY, Kim SW. Effect of Korean Herbal Formula (Modified Ojayeonjonghwan) on Androgen Receptor Expression in an Aging Rat Model of Late Onset Hypogonadism. World J Mens Health. 2019 Jan;37(1):105-112. doi: 10.5534/wjmh.180051. PMID: 30584994; PMCID: PMC6305862.
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Thyrotoxic Periodic Paralysis and Polymorphisms of the ADRB2, AR, and GABRA3 Genes in Men with Graves Disease.

Endocrinology and metabolism (Seoul, Korea)

Park S, Kim TY, Sim S, Lim S, Kim M, Kwon H, Jeon MJ, Kim WG, Shong YK, Kim WB.
PMID: 26676335
Endocrinol Metab (Seoul). 2016 Mar;31(1):142-6. doi: 10.3803/EnM.2016.31.1.142.

BACKGROUND: Thyrotoxic periodic paralysis (TPP) is a rare complication of thyrotoxicosis characterized by acute attacks of muscle weakness and hypokalemia. Recently, variation in several genes was suggested to be associated with TPP. This study evaluated the genetic predisposition to...

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Park S, Kim TY, Sim S, et al. Thyrotoxic Periodic Paralysis and Polymorphisms of the ADRB2, AR, and GABRA3 Genes in Men with Graves Disease. Endocrinol Metab (Seoul). 2016;31(1):142-6doi: 10.3803/EnM.2016.31.1.142.
Park, S., Kim, T. Y., Sim, S., Lim, S., Kim, M., Kwon, H., Jeon, M. J., Kim, W. G., Shong, Y. K., & Kim, W. B. (2016). Thyrotoxic Periodic Paralysis and Polymorphisms of the ADRB2, AR, and GABRA3 Genes in Men with Graves Disease. Endocrinology and metabolism (Seoul, Korea), 31(1), 142-6. https://doi.org/10.3803/EnM.2016.31.1.142
Park, Suyeon, et al. "Thyrotoxic Periodic Paralysis and Polymorphisms of the ADRB2, AR, and GABRA3 Genes in Men with Graves Disease." Endocrinology and metabolism (Seoul, Korea) vol. 31,1 (2016): 142-6. doi: https://doi.org/10.3803/EnM.2016.31.1.142
Park S, Kim TY, Sim S, Lim S, Kim M, Kwon H, Jeon MJ, Kim WG, Shong YK, Kim WB. Thyrotoxic Periodic Paralysis and Polymorphisms of the ADRB2, AR, and GABRA3 Genes in Men with Graves Disease. Endocrinol Metab (Seoul). 2016 Mar;31(1):142-6. doi: 10.3803/EnM.2016.31.1.142. PMID: 26676335; PMCID: PMC4803550.
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Progestogens as a component of menopausal hormone therapy: the right molecule makes the difference.

Drugs in context

Stevenson JC, Rozenberg S, Maffei S, Egarter C, Stute P, Römer T.
PMID: 33312219
Drugs Context. 2020 Dec 02;9. doi: 10.7573/dic.2020-10-1. eCollection 2020.

Optimizing menopausal hormone therapy (MHT) requires an awareness of the benefits and risks associated with the available treatments. This narrative review, which is based on the proceedings of an Advisory Board meeting and supplemented by relevant articles identified in...

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Stevenson JC, Rozenberg S, Maffei S, et al. Progestogens as a component of menopausal hormone therapy: the right molecule makes the difference. Drugs Context. 2020;9doi: 10.7573/dic.2020-10-1.
Stevenson, J. C., Rozenberg, S., Maffei, S., Egarter, C., Stute, P., & Römer, T. (2020). Progestogens as a component of menopausal hormone therapy: the right molecule makes the difference. Drugs in context, 9. https://doi.org/10.7573/dic.2020-10-1
Stevenson, John C, et al. "Progestogens as a component of menopausal hormone therapy: the right molecule makes the difference." Drugs in context vol. 9 (2020). doi: https://doi.org/10.7573/dic.2020-10-1
Stevenson JC, Rozenberg S, Maffei S, Egarter C, Stute P, Römer T. Progestogens as a component of menopausal hormone therapy: the right molecule makes the difference. Drugs Context. 2020 Dec 02;9. doi: 10.7573/dic.2020-10-1. eCollection 2020. PMID: 33312219; PMCID: PMC7716720.
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A triple-negative breast cancer surrogate subtype classification that correlates with gene expression subtypes.

Breast cancer research and treatment

Yoo TK, Kang J, Lee A, Chae BJ.
PMID: 35018542
Breast Cancer Res Treat. 2022 Jan 12; doi: 10.1007/s10549-021-06437-8. Epub 2022 Jan 12.

BACKGROUND: This study developed a triple-negative breast cancer (TNBC) surrogate subtype classification that represents TNBC subtypes based on the Vanderbilt subtype classification.METHODS: Patients who underwent primary curative surgery for TNBC were included. Representative FFPE blocks were used for gene...

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Yoo TK, Kang J, Lee A, et al. A triple-negative breast cancer surrogate subtype classification that correlates with gene expression subtypes. Breast Cancer Res Treat. 2022;doi: 10.1007/s10549-021-06437-8.
Yoo, T. K., Kang, J., Lee, A., & Chae, B. J. (2022). A triple-negative breast cancer surrogate subtype classification that correlates with gene expression subtypes. Breast cancer research and treatment, . https://doi.org/10.1007/s10549-021-06437-8
Yoo, Tae-Kyung, et al. "A triple-negative breast cancer surrogate subtype classification that correlates with gene expression subtypes." Breast cancer research and treatment vol. (2022). doi: https://doi.org/10.1007/s10549-021-06437-8
Yoo TK, Kang J, Lee A, Chae BJ. A triple-negative breast cancer surrogate subtype classification that correlates with gene expression subtypes. Breast Cancer Res Treat. 2022 Jan 12; doi: 10.1007/s10549-021-06437-8. Epub 2022 Jan 12. PMID: 35018542.
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Clinical Significance of Wnt/β-Catenin Signalling and Androgen Receptor Expression in Prostate Cancer.

The world journal of men's health

Jung SJ, Oh S, Lee GT, Chung J, Min K, Yoon J, Kim W, Ryu DS, Kim IY, Kang DI.
PMID: 23658864
World J Mens Health. 2013 Apr;31(1):36-46. doi: 10.5534/wjmh.2013.31.1.36. Epub 2013 Apr 23.

PURPOSE: To investigate the relationships among the Wnt/β-catenin pathway, androgen receptor (AR), and clinicopathological factors in hormone-naïve prostate cancer.MATERIALS AND METHODS: This study was conducted with132 cases of hormone-naïve prostate cancer treated by prostatectomy and prostate needle biopsy. An...

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Jung SJ, Oh S, Lee GT, et al. Clinical Significance of Wnt/β-Catenin Signalling and Androgen Receptor Expression in Prostate Cancer. World J Mens Health. 2013;31(1):36-46doi: 10.5534/wjmh.2013.31.1.36.
Jung, S. J., Oh, S., Lee, G. T., Chung, J., Min, K., Yoon, J., Kim, W., Ryu, D. S., Kim, I. Y., & Kang, D. I. (2013). Clinical Significance of Wnt/β-Catenin Signalling and Androgen Receptor Expression in Prostate Cancer. The world journal of men's health, 31(1), 36-46. https://doi.org/10.5534/wjmh.2013.31.1.36
Jung, Soo Jin, et al. "Clinical Significance of Wnt/β-Catenin Signalling and Androgen Receptor Expression in Prostate Cancer." The world journal of men's health vol. 31,1 (2013): 36-46. doi: https://doi.org/10.5534/wjmh.2013.31.1.36
Jung SJ, Oh S, Lee GT, Chung J, Min K, Yoon J, Kim W, Ryu DS, Kim IY, Kang DI. Clinical Significance of Wnt/β-Catenin Signalling and Androgen Receptor Expression in Prostate Cancer. World J Mens Health. 2013 Apr;31(1):36-46. doi: 10.5534/wjmh.2013.31.1.36. Epub 2013 Apr 23. PMID: 23658864; PMCID: PMC3640151.
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Positive Correlation between Androgen Receptor CAG Repeat Length and Metabolic Syndrome in a Korean Male Population.

The world journal of men's health

Kim JW, Bae YD, Ahn ST, Kim JW, Kim JJ, Moon DG.
PMID: 29299905
World J Mens Health. 2018 Jan;36(1):73-78. doi: 10.5534/wjmh.17029.

PURPOSE: In epidemiological studies, there are various associations of androgen receptor (AR) CAG with several diseases or phenotypes. However, the relationship between CAG repeat length and metabolic syndrome (MS) remains unclear, especially in Asian populations. This study was designed...

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Kim JW, Bae YD, Ahn ST, et al. Positive Correlation between Androgen Receptor CAG Repeat Length and Metabolic Syndrome in a Korean Male Population. World J Mens Health. 2018;36(1):73-78doi: 10.5534/wjmh.17029.
Kim, J. W., Bae, Y. D., Ahn, S. T., Kim, J. W., Kim, J. J., & Moon, D. G. (2018). Positive Correlation between Androgen Receptor CAG Repeat Length and Metabolic Syndrome in a Korean Male Population. The world journal of men's health, 36(1), 73-78. https://doi.org/10.5534/wjmh.17029
Kim, Jong Wook, et al. "Positive Correlation between Androgen Receptor CAG Repeat Length and Metabolic Syndrome in a Korean Male Population." The world journal of men's health vol. 36,1 (2018): 73-78. doi: https://doi.org/10.5534/wjmh.17029
Kim JW, Bae YD, Ahn ST, Kim JW, Kim JJ, Moon DG. Positive Correlation between Androgen Receptor CAG Repeat Length and Metabolic Syndrome in a Korean Male Population. World J Mens Health. 2018 Jan;36(1):73-78. doi: 10.5534/wjmh.17029. PMID: 29299905; PMCID: PMC5756810.
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The Expression of Androgen Receptor and Its Variants in Human Prostate Cancer Tissue according to Disease Status, and Its Prognostic Significance.

The world journal of men's health

Park SW, Kim JH, Lee HJ, Shin DH, Lee SD, Yoon S.
PMID: 29756415
World J Mens Health. 2019 Jan;37(1):68-77. doi: 10.5534/wjmh.180003. Epub 2018 Apr 16.

PURPOSE: To evaluate changes in the expression of androgen receptor (AR) and its variants (ARVs) in human prostate cancer (PCa) tissues according to disease status, and its prognostic significance following radical prostatectomy (RP).MATERIALS AND METHODS: A total of 282...

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Park SW, Kim JH, Lee HJ, et al. The Expression of Androgen Receptor and Its Variants in Human Prostate Cancer Tissue according to Disease Status, and Its Prognostic Significance. World J Mens Health. 2018;37(1):68-77doi: 10.5534/wjmh.180003.
Park, S. W., Kim, J. H., Lee, H. J., Shin, D. H., Lee, S. D., & Yoon, S. (2019). The Expression of Androgen Receptor and Its Variants in Human Prostate Cancer Tissue according to Disease Status, and Its Prognostic Significance. The world journal of men's health, 37(1), 68-77. https://doi.org/10.5534/wjmh.180003
Park, Sung Woo, et al. "The Expression of Androgen Receptor and Its Variants in Human Prostate Cancer Tissue according to Disease Status, and Its Prognostic Significance." The world journal of men's health vol. 37,1 (2019): 68-77. doi: https://doi.org/10.5534/wjmh.180003
Park SW, Kim JH, Lee HJ, Shin DH, Lee SD, Yoon S. The Expression of Androgen Receptor and Its Variants in Human Prostate Cancer Tissue according to Disease Status, and Its Prognostic Significance. World J Mens Health. 2019 Jan;37(1):68-77. doi: 10.5534/wjmh.180003. Epub 2018 Apr 16. PMID: 29756415; PMCID: PMC6305860.
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Immunohistochemical Expression of Androgen Receptors (AR) in Various Breast Cancer Subtypes.

Open access Macedonian journal of medical sciences

Ismael NEHS, Khairy RA, Talaat SM, El-Fattah FAA.
PMID: 31110566
Open Access Maced J Med Sci. 2019 Apr 29;7(8):1259-1265. doi: 10.3889/oamjms.2019.311. eCollection 2019 Apr 30.

BACKGROUND: Breast carcinoma ranks the first among malignant tumours in females and is the chief cause of cancer-related mortality. Androgen in implicated in the induction of proliferation and growth of mammary cells through binding to their corresponding receptors. Androgens...

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Ismael NEHS, Khairy RA, Talaat SM, et al. Immunohistochemical Expression of Androgen Receptors (AR) in Various Breast Cancer Subtypes. Open Access Maced J Med Sci. 2019;7(8):1259-1265doi: 10.3889/oamjms.2019.311.
Ismael, N. E. H. S., Khairy, R. A., Talaat, S. M., & El-Fattah, F. A. A. (2019). Immunohistochemical Expression of Androgen Receptors (AR) in Various Breast Cancer Subtypes. Open access Macedonian journal of medical sciences, 7(8), 1259-1265. https://doi.org/10.3889/oamjms.2019.311
Ismael, Nour El Hoda S, et al. "Immunohistochemical Expression of Androgen Receptors (AR) in Various Breast Cancer Subtypes." Open access Macedonian journal of medical sciences vol. 7,8 (2019): 1259-1265. doi: https://doi.org/10.3889/oamjms.2019.311
Ismael NEHS, Khairy RA, Talaat SM, El-Fattah FAA. Immunohistochemical Expression of Androgen Receptors (AR) in Various Breast Cancer Subtypes. Open Access Maced J Med Sci. 2019 Apr 29;7(8):1259-1265. doi: 10.3889/oamjms.2019.311. eCollection 2019 Apr 30. PMID: 31110566; PMCID: PMC6514328.
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Prognostic Role of Androgen Receptor Expression in Surgically Resected Early Breast Cancer Patients.

Journal of breast cancer

Yang Y, Min A, Lee KH, Ryu HS, Kim TY, Woo GU, Suh KJ, Lee DW, Lee HB, Moon HG, Han W, Park IA, Noh DY, Im SA.
PMID: 32395377
J Breast Cancer. 2020 Apr 20;23(2):182-193. doi: 10.4048/jbc.2020.23.e28. eCollection 2020 Apr.

PURPOSE: Endocrine therapy is a standard treatment for hormone receptor-positive breast cancer, which accounts for 60%-75% of all breast cancer. Hormone receptor positivity is a prognostic and predictive biomarker in breast cancer. Approximately 50%-80% of breast cancer is also...

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Yang Y, Min A, Lee KH, et al. Prognostic Role of Androgen Receptor Expression in Surgically Resected Early Breast Cancer Patients. J Breast Cancer. 2020;23(2):182-193doi: 10.4048/jbc.2020.23.e28.
Yang, Y., Min, A., Lee, K. H., Ryu, H. S., Kim, T. Y., Woo, G. U., Suh, K. J., Lee, D. W., Lee, H. B., Moon, H. G., Han, W., Park, I. A., Noh, D. Y., & Im, S. A. (2020). Prognostic Role of Androgen Receptor Expression in Surgically Resected Early Breast Cancer Patients. Journal of breast cancer, 23(2), 182-193. https://doi.org/10.4048/jbc.2020.23.e28
Yang, Yaewon, et al. "Prognostic Role of Androgen Receptor Expression in Surgically Resected Early Breast Cancer Patients." Journal of breast cancer vol. 23,2 (2020): 182-193. doi: https://doi.org/10.4048/jbc.2020.23.e28
Yang Y, Min A, Lee KH, Ryu HS, Kim TY, Woo GU, Suh KJ, Lee DW, Lee HB, Moon HG, Han W, Park IA, Noh DY, Im SA. Prognostic Role of Androgen Receptor Expression in Surgically Resected Early Breast Cancer Patients. J Breast Cancer. 2020 Apr 20;23(2):182-193. doi: 10.4048/jbc.2020.23.e28. eCollection 2020 Apr. PMID: 32395377; PMCID: PMC7192742.
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Effects of a Proteasome Inhibitor on Cardiomyocytes in a Pressure-Overload Hypertrophy Rat Model: An Animal Study.

The Korean journal of thoracic and cardiovascular surgery

Kim IS, Jo WM.
PMID: 28593149
Korean J Thorac Cardiovasc Surg. 2017 Jun;50(3):144-152. doi: 10.5090/kjtcs.2017.50.3.144. Epub 2017 Jun 05.

BACKGROUND: The ubiquitin-proteasome system (UPS) is an important pathway of proteolysis in pathologic hypertrophic cardiomyocytes. We hypothesize that MG132, a proteasome inhibitor, might prevent hypertrophic cardiomyopathy (CMP) by blocking the UPS. Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB)...

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Kim IS, Jo WM. Effects of a Proteasome Inhibitor on Cardiomyocytes in a Pressure-Overload Hypertrophy Rat Model: An Animal Study. Korean J Thorac Cardiovasc Surg. 2017;50(3):144-152doi: 10.5090/kjtcs.2017.50.3.144.
Kim, I. S., & Jo, W. M. (2017). Effects of a Proteasome Inhibitor on Cardiomyocytes in a Pressure-Overload Hypertrophy Rat Model: An Animal Study. The Korean journal of thoracic and cardiovascular surgery, 50(3), 144-152. https://doi.org/10.5090/kjtcs.2017.50.3.144
Kim, In-Sub, and Jo, Won-Min. "Effects of a Proteasome Inhibitor on Cardiomyocytes in a Pressure-Overload Hypertrophy Rat Model: An Animal Study." The Korean journal of thoracic and cardiovascular surgery vol. 50,3 (2017): 144-152. doi: https://doi.org/10.5090/kjtcs.2017.50.3.144
Kim IS, Jo WM. Effects of a Proteasome Inhibitor on Cardiomyocytes in a Pressure-Overload Hypertrophy Rat Model: An Animal Study. Korean J Thorac Cardiovasc Surg. 2017 Jun;50(3):144-152. doi: 10.5090/kjtcs.2017.50.3.144. Epub 2017 Jun 05. PMID: 28593149; PMCID: PMC5460960.
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