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Showing 1 to 12 of 70 entries
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Involvement of the CXCL12 System in the Stimulatory Effects of Prenatal Exposure to High-Fat Diet on Hypothalamic Orexigenic Peptides and Behavior in Offspring.

Frontiers in behavioral neuroscience

Poon K, Barson JR, Shi H, Chang GQ, Leibowitz SF.
PMID: 28567007
Front Behav Neurosci. 2017 May 17;11:91. doi: 10.3389/fnbeh.2017.00091. eCollection 2017.

Exposure to a high fat diet (HFD) during gestation stimulates neurogenesis and expression of hypothalamic orexigenic neuropeptides that affect consummatory and emotional behaviors. With recent studies showing a HFD to increase inflammation, this report investigated the neuroinflammatory chemokine, CXCL12,...

Expression of CXC chemokine receptor-4 and forkhead box 3 in neuroblastoma cells and response to chemotherapy.

Oncology letters

Sun J, Feng C, Liao W, Zhang H, Tang S.
PMID: 24932293
Oncol Lett. 2014 Jun;7(6):2083-2088. doi: 10.3892/ol.2014.2028. Epub 2014 Apr 03.

Current evidence indicates that the abnormal expression of chemokines or their receptors, such as CXC chemokine receptor-4 (CXCR4), is positively correlated with the development, progression and metastasis of tumor cells. However, the role of CXCR4 in neuroblastoma and its...

CXCL12 chemokine and GABA neurotransmitter systems crosstalk and their putative roles.

Frontiers in cellular neuroscience

Guyon A.
PMID: 24808825
Front Cell Neurosci. 2014 Apr 28;5:115. doi: 10.3389/fncel.2014.00115. eCollection 2014.

Since CXCL12 and its receptors, CXCR4 and CXCR7, have been found in the brain, the role of this chemokine has been expanded from chemoattractant in the immune system to neuromodulatory in the brain. Several pieces of evidence suggest that...

Fibrocytes in the fibrotic lung: altered phenotype detected by flow cytometry.

Frontiers in pharmacology

Reese C, Lee R, Bonner M, Perry B, Heywood J, Silver RM, Tourkina E, Visconti RP, Hoffman S.
PMID: 24999331
Front Pharmacol. 2014 Jun 16;5:141. doi: 10.3389/fphar.2014.00141. eCollection 2014.

Fibrocytes are bone marrow hematopoietic-derived cells that also express a mesenchymal cell marker (commonly collagen I) and participate in fibrotic diseases of multiple organs. Given their origin, they or their precursors must be circulating cells before recruitment into target...

Migration, proliferation, and differentiation of cord blood mesenchymal stromal cells treated with histone deacetylase inhibitor valproic Acid.

Stem cells international

Marquez-Curtis LA, Qiu Y, Xu A, Janowska-Wieczorek A.
PMID: 24757448
Stem Cells Int. 2014;2014:610495. doi: 10.1155/2014/610495. Epub 2014 Mar 16.

Mesenchymal stromal cells (MSC) have great potential for cellular therapies as they can be directed to differentiate into certain lineages or to exert paracrine effects at sites of injury. The interactions between stromal cell-derived factor (SDF)-1 and its receptors...

Prognostic significance of SDF-1 chemokine and its receptors CXCR4 and CXCR7 involved in EMT of prostate cancer.

Cytokine

Parol-Kulczyk M, Gzil A, Ligmanowska J, Grzanka D.
PMID: 34920230
Cytokine. 2021 Dec 15;150:155778. doi: 10.1016/j.cyto.2021.155778. Epub 2021 Dec 15.

Tendency to conversion from state of chronic inflammation to malignancy is a tumor characteristic trait, which encourages progression to its metastatic stage.. The inflammatory cells maintaining in the tumor inaugurate a communication with cancer cells and become tumor-fostering cells....

CXCR4-CCR7 Heterodimerization Is a Driver of Breast Cancer Progression.

Life (Basel, Switzerland)

Poltavets V, Faulkner JW, Dhatrak D, Whitfield RJ, McColl SR, Kochetkova M.
PMID: 34685420
Life (Basel). 2021 Oct 07;11(10). doi: 10.3390/life11101049.

Metastatic breast cancer has one of the highest mortality rates among women in western society. Chemokine receptors CXCR4 and CCR7 have been shown to be linked to the metastatic spread of breast cancer, however, their precise function and underlying...

CXCR4 and CXCR7 Inhibition Ameliorates the Formation of Platelet-Neutrophil Complexes and Neutrophil Extracellular Traps through Adora2b Signaling.

International journal of molecular sciences

Ngamsri KC, Putri RA, Jans C, Schindler K, Fuhr A, Zhang Y, Gamper-Tsigaras J, Ehnert S, Konrad FM.
PMID: 34948374
Int J Mol Sci. 2021 Dec 17;22(24). doi: 10.3390/ijms222413576.

Peritonitis and peritonitis-associated sepsis are characterized by an increased formation of platelet-neutrophil complexes (PNCs), which contribute to an excessive migration of polymorphonuclear neutrophils (PMN) into the inflamed tissue. An important neutrophilic mechanism to capture and kill invading pathogens is...

Prognostic significance of SDF-1 chemokine and its receptors CXCR4 and CXCR7 involved in EMT of prostate cancer.

Cytokine

Parol-Kulczyk M, Gzil A, Ligmanowska J, Grzanka D.
PMID: 34920230
Cytokine. 2021 Dec 15;150:155778. doi: 10.1016/j.cyto.2021.155778. Epub 2021 Dec 15.

Tendency to conversion from state of chronic inflammation to malignancy is a tumor characteristic trait, which encourages progression to its metastatic stage.. The inflammatory cells maintaining in the tumor inaugurate a communication with cancer cells and become tumor-fostering cells....

Characterization of Plasmodium falciparum macrophage migration inhibitory factor homologue and its cysteine deficient mutants.

Parasitology international

Schipper S, Springer E, Hahn J, Rahlfs S, Bourilhon P, Bernhagen J, Becker K, Przyborski JM.
PMID: 34785370
Parasitol Int. 2021 Nov 14;87:102513. doi: 10.1016/j.parint.2021.102513. Epub 2021 Nov 14.

Plasmodium falciparum macrophage migration inhibitory factor (PfMIF) is a homologue of the multifunctional human host cytokine MIF (HsMIF). Upon schizont rupture it is released into the human blood stream where it acts as a virulence factor, modulating the host...

Prognostic significance of SDF-1 chemokine and its receptors CXCR4 and CXCR7 involved in EMT of prostate cancer.

Cytokine

Parol-Kulczyk M, Gzil A, Ligmanowska J, Grzanka D.
PMID: 34920230
Cytokine. 2021 Dec 15;150:155778. doi: 10.1016/j.cyto.2021.155778. Epub 2021 Dec 15.

Tendency to conversion from state of chronic inflammation to malignancy is a tumor characteristic trait, which encourages progression to its metastatic stage.. The inflammatory cells maintaining in the tumor inaugurate a communication with cancer cells and become tumor-fostering cells....

Characterization of Plasmodium falciparum macrophage migration inhibitory factor homologue and its cysteine deficient mutants.

Parasitology international

Schipper S, Springer E, Hahn J, Rahlfs S, Bourilhon P, Bernhagen J, Becker K, Przyborski JM.
PMID: 34785370
Parasitol Int. 2021 Nov 14;87:102513. doi: 10.1016/j.parint.2021.102513. Epub 2021 Nov 14.

Plasmodium falciparum macrophage migration inhibitory factor (PfMIF) is a homologue of the multifunctional human host cytokine MIF (HsMIF). Upon schizont rupture it is released into the human blood stream where it acts as a virulence factor, modulating the host...

Showing 1 to 12 of 70 entries