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Showing 1 to 12 of 23 entries
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Expression of e-cadherin, leukemia inhibitory factor and progesterone receptor in mouse blastocysts after ovarian stimulation.

Cell journal

Movaghar B, Askarian S.
PMID: 23508459
Cell J. 2012;14(3):225-30. Epub 2012 Dec 12.

OBJECTIVE: The appropriate interaction between a blastocyst and the endometrium is essential for successful implantation. Numerous factors, including hormone receptors (progesterone receptor), cytokines [leukemia inhibitory factors (LIF)], and adherence molecules such as E-cadherin are involved in the cross-talk that...

Loss of Progesterone Receptor Expression Is an Early Tumorigenesis Event Associated with Tumor Progression and Shorter Survival in Pancreatic Neuroendocrine Tumor Patients.

Journal of pathology and translational medicine

Kim SJ, An S, Lee JH, Kim JY, Song KB, Hwang DW, Kim SC, Yu E, Hong SM.
PMID: 28597868
J Pathol Transl Med. 2017 Jul;51(4):388-395. doi: 10.4132/jptm.2017.03.19. Epub 2017 Jun 08.

BACKGROUND: Pancreatic neuroendocrine tumors (PanNETs) are the second most common pancreatic neoplasms and there is no well-elucidated biomarker to stratify their detection and prognosis. Previous studies have reported that progesterone receptor (PR) expression status was associated with poorer survival...

The prognostic value and clinical utility of estrogen and progesterone receptors in endometrial carcinoma.

Primary care update for Ob/Gyns

Gehrig PA, Van Le L.
PMID: 10725672
Prim Care Update Ob Gyns. 2000 Mar 01;7(2):55-59. doi: 10.1016/s1068-607x(00)00021-4.

In the United States, endometrial carcinoma is the most common gynecologic malignancy, and accounts for 4,900 deaths per year in the United States. While this disease has relatively good cure rates, there is motivation to describe other determinants, which...

Expression of female sex hormone receptors and its relation to clinicopathological characteristics and prognosis of lung adenocarcinoma.

Journal of pathology and translational medicine

Lee JH, Kim HK, Shin BK.
PMID: 31718122
J Pathol Transl Med. 2020 Jan;54(1):103-111. doi: 10.4132/jptm.2019.10.12. Epub 2019 Nov 13.

BACKGROUND: Adenocarcinoma (ADC) of the lung exhibits different clinicopathological characteristics in men and women. Recent studies have suggested that these differences originate from the expression of female sex hormone receptors in tumor cells. The aim of the present study...

Elastosis in Breast Cancer as a Surrogate Marker for Estrogen Receptor Positivity.

Oman medical journal

Al Abri S, Al Rawahi A, Rao L.
PMID: 33898059
Oman Med J. 2021 Mar 31;36(2):e247. doi: 10.5001/omj.2021.60. eCollection 2021 Mar.

OBJECTIVES: We sought to describe the occurrence of stromal elastosis in breast carcinoma among Omani female patients using semi-quantitative methods. We also sought to investigate the relationship between stromal elastosis and estrogen receptor (ER), progesterone receptor (PR), HER2/neu receptor...

Ciliated and Mucinous Adenomatous Syringometaplasia: The Missing Link of the "Ciliated Eccrine Metaplasia" Theory in the Histogenesis of Cutaneous Eccrine Ciliated Cyst?.

The American Journal of dermatopathology

Tran TAN.
PMID: 33606368
Am J Dermatopathol. 2021 Nov 01;43(11):827-830. doi: 10.1097/DAD.0000000000001924.

ABSTRACT: A variety of metaplastic changes has been reported in eccrine ducts and glands with squamous and mucinous syringometaplasia representing the most common histopathologic patterns. In the current case, a previously unreported variant of syringometaplasia was described in a...

Immunotherapy for Triple-Negative Breast Cancer.

Pharmaceutics

Cao Y, Chen C, Tao Y, Lin W, Wang P.
PMID: 34959285
Pharmaceutics. 2021 Nov 25;13(12). doi: 10.3390/pharmaceutics13122003.

Triple-negative breast cancer (TNBC) is characterized by extensive tumor heterogeneity at both the pathologic and molecular levels, particularly accelerated aggressiveness, and terrible metastasis. It is responsible for the increased mortality of breast cancer patients. Due to the negative expression...

Emerging Role of PARP Inhibitors in Metastatic Triple Negative Breast Cancer. Current Scenario and Future Perspectives.

Frontiers in oncology

Barchiesi G, Roberto M, Verrico M, Vici P, Tomao S, Tomao F.
PMID: 34900718
Front Oncol. 2021 Nov 25;11:769280. doi: 10.3389/fonc.2021.769280. eCollection 2021.

Triple negative tumors represent 15% of breast cancer and are characterized by the lack of estrogen receptors, progesterone receptor, and HER2 amplification or overexpression. Approximately 25% of patients diagnosed with triple negative breast cancer carry a germline BRCA1 or...

Therapeutic effects of progesterone and its metabolites in traumatic brain injury may involve non-classical signaling mechanisms.

Frontiers in neuroscience

Cooke PS, Nanjappa MK, Yang Z, Wang KK.
PMID: 23781171
Front Neurosci. 2013 Jun 13;7:108. doi: 10.3389/fnins.2013.00108. eCollection 2013.

Traumatic brain injury (TBI) is an important and costly medical problem for which no clinically proven treatment currently exists. Studies in rodents and humans have shown beneficial effects of progesterone (P4) on both mortality and functional outcomes following TBI....

Association of mammographic density with pathologic findings.

Iranian Red Crescent medical journal

Ahmadinejad N, Movahedinia S, Movahedinia S, Shahriari M.
PMID: 24693404
Iran Red Crescent Med J. 2013 Dec;15(12):e16698. doi: 10.5812/ircmj.16698. Epub 2013 Dec 05.

BACKGROUND: Breast cancer is one of the most common cancers in the world and is the first cause of death due to cancer among women. Mammography is the best screening method and mammographic density, which determines the percentage of...

Analysis of the molecular subtypes of preoperative core needle biopsy and surgical specimens in invasive breast cancer.

Journal of pathology and translational medicine

Jeong YS, Kang J, Lee J, Yoo TK, Kim SH, Lee A.
PMID: 31718121
J Pathol Transl Med. 2020 Jan;54(1):87-94. doi: 10.4132/jptm.2019.10.14. Epub 2019 Nov 13.

BACKGROUND: Accurate molecular classification of breast core needle biopsy (CNB) tissue is important for determining neoadjuvant systemic therapies for invasive breast cancer. The researchers aimed to evaluate the concordance rate (CR) of molecular subtypes between CNBs and surgical specimens.METHODS:...

Effect of postoperative ischemia on steroid hormone receptors and c-erbB-2 levels in breast cancer tissue.

Turkish journal of surgery

Saydam M, Yılmaz İ.
PMID: 30248295
Turk J Surg. 2018 Sep 18;1-5. doi: 10.5152/turkjsurg.2018.4001. Epub 2018 Sep 18.

OBJECTIVES: Postoperative ischemia could affect the evaluation of breast cancer tissue for steroid hormone receptors and c-erbB2 levels until fixation using formalin. The misevaluation of steroid hormone receptors and c-erbB2 levels, which are important prognostic factors in the treatment...

Showing 1 to 12 of 23 entries