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Lubiprostone Increases Small Intestinal Smooth Muscle Contractions Through a Prostaglandin E Receptor 1 (EP1)-mediated Pathway.

Journal of neurogastroenterology and motility

Chan WW, Mashimo H.
PMID: 23875097
J Neurogastroenterol Motil. 2013 Jul;19(3):312-8. doi: 10.5056/jnm.2013.19.3.312. Epub 2013 Jul 08.

BACKGROUND/AIMS: Lubiprostone, a chloride channel type 2 (ClC-2) activator, was thought to treat constipation by enhancing intestinal secretion. It has been associated with increased intestinal transit and delayed gastric emptying. Structurally similar to prostones with up to 54% prostaglandin...

Cite
Chan WW, Mashimo H. Lubiprostone Increases Small Intestinal Smooth Muscle Contractions Through a Prostaglandin E Receptor 1 (EP1)-mediated Pathway. J Neurogastroenterol Motil. 2013;19(3):312-8doi: 10.5056/jnm.2013.19.3.312.
Chan, W. W., & Mashimo, H. (2013). Lubiprostone Increases Small Intestinal Smooth Muscle Contractions Through a Prostaglandin E Receptor 1 (EP1)-mediated Pathway. Journal of neurogastroenterology and motility, 19(3), 312-8. https://doi.org/10.5056/jnm.2013.19.3.312
Chan, Walter W, and Mashimo, Hiroshi. "Lubiprostone Increases Small Intestinal Smooth Muscle Contractions Through a Prostaglandin E Receptor 1 (EP1)-mediated Pathway." Journal of neurogastroenterology and motility vol. 19,3 (2013): 312-8. doi: https://doi.org/10.5056/jnm.2013.19.3.312
Chan WW, Mashimo H. Lubiprostone Increases Small Intestinal Smooth Muscle Contractions Through a Prostaglandin E Receptor 1 (EP1)-mediated Pathway. J Neurogastroenterol Motil. 2013 Jul;19(3):312-8. doi: 10.5056/jnm.2013.19.3.312. Epub 2013 Jul 08. PMID: 23875097; PMCID: PMC3714408.
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