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Newer agents in antiplatelet therapy: a review.

Journal of blood medicine

Yeung J, Holinstat M.
PMID: 22792011
J Blood Med. 2012;3:33-42. doi: 10.2147/JBM.S25421. Epub 2012 Jun 25.

Antiplatelet therapy remains the mainstay in preventing aberrant platelet activation in pathophysiological conditions such as myocardial infarction, ischemia, and stroke. Although there has been significant advancement in antiplatelet therapeutic approaches, aspirin still remains the gold standard treatment in the...

Paxillin is an intrinsic negative regulator of platelet activation in mice.

Thrombosis journal

Sakata A, Ohmori T, Nishimura S, Suzuki H, Madoiwa S, Mimuro J, Kario K, Sakata Y.
PMID: 24383745
Thromb J. 2014 Jan 02;12(1):1. doi: 10.1186/1477-9560-12-1.

BACKGROUND: Paxillin is a LIM domain protein localized at integrin-mediated focal adhesions. Although paxillin is thought to modulate the functions of integrins, little is known about the contribution of paxillin to signaling pathways in platelets. Here, we studied the...

Showing 1 to 2 of 2 entries