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Showing 1 to 12 of 57 entries
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Reactive Oxygen Species and Serous Epithelial Ovarian Adenocarcinoma.

Cancer research journal

Cohen S, Mehrabi S, Yao X, Millingen S, Aikhionbare FO.
PMID: 28503633
Cancer Res J (N Y N Y). 2016 Nov;4(6):106-114. doi: 10.11648/j.crj.20160406.13. Epub 2017 Jan 09.

Serous ovarian cancer (SOC) is usually diagnosed at late stage and stage-adjusted five year survival rate is low. Mortality is relatively heavy on African-Americans/Black (AA) affected with SOC compared to their Caucasian counterparts, though the cause for the disparity...

Context matters: A community-based study of urban minority parents' views on child health.

Journal of the Georgia Public Health Association

Bolar CL, Hernandez N, Akintobi TH, McAllister C, Ferguson AS, Rollins L, Wrenn G, Okafor M, Collins D, Clem T.
PMID: 27275021
J Ga Public Health Assoc. 2016;5(3):212-219.

BACKGROUND: Among children, there are substantial ethno-racial minority disparities across a broad range of health-related behaviors, experiences, and outcomes. Addressing these disparities is important, as childhood and adolescence establish health trajectories that extend throughout life.METHODS: The current study employed...

Spatiotemporal patterns of GFAP upregulation in rat brain following acute intoxication with diisopropylfluorophosphate (DFP).

Current neurobiology

Liu C, Li Y, Lein PJ, Ford BD.
PMID: 24039349
Curr Neurobiol. 2012 Jul;3(2):90-97.

We previously demonstrated that the organophosphate diisopropylfluorophosphate (DFP) induced region-specific delayed neuronal injury in rat brain. The goal of this study was to examine the spatiotemporal pattern of the astroglial response after acute intoxication of rats with DFP. Rats...

Alterations in molecular pathways in the retina of early experimental glaucoma eyes.

International journal of physiology, pathophysiology and pharmacology

Cao L, Wang L, Cull G, Zhou A.
PMID: 26069528
Int J Physiol Pathophysiol Pharmacol. 2015 Mar 20;7(1):44-53. eCollection 2015.

Glaucoma is a multifactorial, neurodegenerative disease. The molecular mechanisms that underlie the pathophysiological changes in glaucomatous eyes, especially at the early stage of the disease, are poorly understood. Here, we report the findings from a quantitative proteomic analysis of...

A Novel Pathway that Links Caveolin-1 Down-Regulation to BRCA1 Dysfunction in Serous Epithelial Ovarian Cancer Cells.

Enliven. Challenges in cancer detection and therapy

Xu J, Agyemang S, Qin Y, Aysola K, Giles M, Oprea G, O'Regan RM, Partridge EE, Harris-Hooker S, Rice VM, Reddy ES, Rao VN.
PMID: 25594072
Enliven Chall Cancer Detect Ther. 2014;1(1). doi: 10.18650/2376-046x.11004.

Ovarian cancer is the second most common gynecological cancer and the five-year survival rate is only about 40%. High-grade serous carcinoma is the pre-dominant histotype associated with hereditary ovarian cancer and women with inherited mutations in BRCA1 have a...

A Comparison of Logistic Regression, Logic Regression, Classification Tree, and Random Forests to Identify Effective Gene-Gene and Gene-Environmental Interactions.

International journal of applied science and technology

Yoo W, Ference BA, Cote ML, Schwartz A.
PMID: 23795347
Int J Appl Sci Technol. 2012 Aug;2(7):268.

Genome wide association studies (GWAS) have identified numerous single nucleotide polymorphisms (SNPs) that are associated with a variety of common human diseases. Due to the weak marginal effect of most disease-associated SNPs, attention has recently turned to evaluating the...

Elevated circulating angiogenic progenitors and white blood cells are associated with hypoxia-inducible angiogenic growth factors in children with sickle cell disease.

Anemia

Ofori-Acquah SF, Buchanan ID, Osunkwo I, Manlove-Simmons J, Lawal F, Quarshie A, Quyyumi AA, Gibbons GH, Gee BE.
PMID: 22675614
Anemia. 2012;2012:156598. doi: 10.1155/2012/156598. Epub 2012 May 23.

We studied the number and function of angiogenic progenitor cells and growth factors in children aged 5-18 years without acute illness, 43 with Hemoglobin SS and 68 with normal hemoglobin. Hemoglobin SS subjects had at least twice as many...

The Relationship Between Obesity and Depression Among Adolescents.

Psychiatric annals

Nemiary D, Shim R, Mattox G, Holden K.
PMID: 23976799
Psychiatr Ann. 2012 Aug 01;42(8):305-308. doi: 10.3928/00485713-20120806-09.

No abstract available.

The role of ASICS in cerebral ischemia.

Wiley interdisciplinary reviews. Membrane transport and signaling

Xiong ZG, Xu TL.
PMID: 23181201
Wiley Interdiscip Rev Membr Transp Signal. 2012;1(5):655-662. doi: 10.1002/wmts.57. Epub 2012 Aug 06.

Cerebral ischemia is a leading cause of death and long-term disabilities worldwide. Excessive intracellular Ca(2+) accumulation in neurons has been considered essential for neuronal injury associated with cerebral ischemia. Although the involvement of glutamate receptors in neuronal Ca(2+) accumulation...

Antibody Microarray Analysis of Signaling Networks Regulated by Cxcl13 and Cxcr5 in Prostate Cancer.

Journal of proteomics & bioinformatics

El-Haibi CP, Singh R, Gupta P, Sharma PK, Greenleaf KN, Singh S, Lillard JW.
PMID: 24009409
J Proteomics Bioinform. 2012;5(8):177-184. doi: 10.4172/jpb.1000232.

Advanced prostate cancer (PCa) often spreads to distant organs, leading to increased morbidity and mortality. It is now well established that chemokines and their cognate receptors play a crucial role in the multi-step process of metastasis. We have previously...

TRPM7 is a unique target for therapeutic intervention of stroke.

International journal of physiology, pathophysiology and pharmacology

Lin J, Xiong ZG.
PMID: 29348798
Int J Physiol Pathophysiol Pharmacol. 2017 Dec 25;9(6):211-216. eCollection 2017.

Ischemic stroke is a leading cause of death and long-term disabilities. The current therapy is limited to thrombolysis and mechanical recanalization, which have limited success. A better understanding of the mechanisms underlying ischemic brain injury is therefore needed for...

DNA Methylation Signature of Post-injury Neointimal Cells During Vascular Remodeling in the Rat Balloon Injury Model.

Molecular biology (Los Angeles, Calif.)

Richards J, Ogoe HA, Li W, Babayewa O, Xu W, Bythwood T, Garcia-Barrios M, Ma L, Song Q.
PMID: 27857867
Mol Biol (Los Angel). 2016 Jul;5(3). doi: 10.4172/2168-9547.1000163. Epub 2016 May 18.

Vascular smooth muscle cell (VSMC) accumulation in the neointimal is a common feature in vascular diseases such as atherosclerosis, transplant arteriosclerosis and restenosis. In this study, we isolated the neointimal cells and uninjured residential vascular smooth muscle cells by...

Showing 1 to 12 of 57 entries