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Showing 1 to 12 of 38 entries
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Dammarane Sapogenins Ameliorates Neurocognitive Functional Impairment Induced by Simulated Long-Duration Spaceflight.

Frontiers in pharmacology

Wu X, Li D, Liu J, Diao L, Ling S, Li Y, Gao J, Fan Q, Sun W, Li Q, Zhao D, Zhong G, Cao D, Liu M, Wang J, Zhao S, Liu Y, Bai G, Shi H, Xu Z, Wang J, Xue C, Jin X, Yuan X, Li H, Liu C, Sun H, Li J, Li Y, Li Y.
PMID: 28611667
Front Pharmacol. 2017 May 29;8:315. doi: 10.3389/fphar.2017.00315. eCollection 2017.

Increasing evidence indicates the occurrence of cognitive impairment in astronauts under spaceflight compound conditions, but the underlying mechanisms and countermeasures need to be explored. In this study, we found that learning and memory abilities were significantly reduced in rats...

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Wu X, Li D, Liu J, et al. Dammarane Sapogenins Ameliorates Neurocognitive Functional Impairment Induced by Simulated Long-Duration Spaceflight. Front Pharmacol. 2017;8:315doi: 10.3389/fphar.2017.00315.
Wu, X., Li, D., Liu, J., Diao, L., Ling, S., Li, Y., Gao, J., Fan, Q., Sun, W., Li, Q., Zhao, D., Zhong, G., Cao, D., Liu, M., Wang, J., Zhao, S., Liu, Y., Bai, G., Shi, H., Xu, Z., Wang, J., Xue, C., Jin, X., Yuan, X., Li, H., Liu, C., Sun, H., Li, J., Li, Y., & Li, Y. (2017). Dammarane Sapogenins Ameliorates Neurocognitive Functional Impairment Induced by Simulated Long-Duration Spaceflight. Frontiers in pharmacology, 8315. https://doi.org/10.3389/fphar.2017.00315
Wu, Xiaorui, et al. "Dammarane Sapogenins Ameliorates Neurocognitive Functional Impairment Induced by Simulated Long-Duration Spaceflight." Frontiers in pharmacology vol. 8 (2017): 315. doi: https://doi.org/10.3389/fphar.2017.00315
Wu X, Li D, Liu J, Diao L, Ling S, Li Y, Gao J, Fan Q, Sun W, Li Q, Zhao D, Zhong G, Cao D, Liu M, Wang J, Zhao S, Liu Y, Bai G, Shi H, Xu Z, Wang J, Xue C, Jin X, Yuan X, Li H, Liu C, Sun H, Li J, Li Y, Li Y. Dammarane Sapogenins Ameliorates Neurocognitive Functional Impairment Induced by Simulated Long-Duration Spaceflight. Front Pharmacol. 2017 May 29;8:315. doi: 10.3389/fphar.2017.00315. eCollection 2017. PMID: 28611667; PMCID: PMC5446991.
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Sapogenins from Trigonella polycerata.

Planta medica

Sharma GL, Kamal R.
PMID: 17401843
Planta Med. 1981 Feb;41(2):203-4. doi: 10.1055/s-2007-971703.

No abstract available.

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Sharma GL, Kamal R. Sapogenins from Trigonella polycerata. Planta Med. 1981;41(2):203-4doi: 10.1055/s-2007-971703.
Sharma, G. L., & Kamal, R. (1981). Sapogenins from Trigonella polycerata. Planta medica, 41(2), 203-4. https://doi.org/10.1055/s-2007-971703
Sharma, G L, and Kamal, R. "Sapogenins from Trigonella polycerata." Planta medica vol. 41,2 (1981): 203-4. doi: https://doi.org/10.1055/s-2007-971703
Sharma GL, Kamal R. Sapogenins from Trigonella polycerata. Planta Med. 1981 Feb;41(2):203-4. doi: 10.1055/s-2007-971703. PMID: 17401843.
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Glyyunnansapogenins G and H: Two New Pentacyclic Triterpenoids of the 18alphaH-Oleana-9(11),12-diene Type from Glycyrrhiza yunnanensis Roots.

Planta medica

Zeng L, Zhang RY, Wang D, Zhang ZL, Lou ZC.
PMID: 17226143
Planta Med. 1991 Apr;57(2):165-8. doi: 10.1055/s-2006-960057.

Two new pentacyclic triterpenoid sapogenins of the 18alpha H-oleana-9(11),12-diene type named glyyunnansapogenins G and H were isolated from the roots of GLYCYRRHIZA YUNNANENSIS Cheng f. et L. K. Tai. Their structures were elucidated as 18alpha H-oleana-9(11),12-diene-3beta,21alpha,29-triol and 18alpha H-3beta,21alpha-dihydroxyoleana-9(11),12-dien-29-oic...

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Zeng L, Zhang RY, Wang D, et al. Glyyunnansapogenins G and H: Two New Pentacyclic Triterpenoids of the 18alphaH-Oleana-9(11),12-diene Type from Glycyrrhiza yunnanensis Roots. Planta Med. 1991;57(2):165-8doi: 10.1055/s-2006-960057.
Zeng, L., Zhang, R. Y., Wang, D., Zhang, Z. L., & Lou, Z. C. (1991). Glyyunnansapogenins G and H: Two New Pentacyclic Triterpenoids of the 18alphaH-Oleana-9(11),12-diene Type from Glycyrrhiza yunnanensis Roots. Planta medica, 57(2), 165-8. https://doi.org/10.1055/s-2006-960057
Zeng, L, et al. "Glyyunnansapogenins G and H: Two New Pentacyclic Triterpenoids of the 18alphaH-Oleana-9(11),12-diene Type from Glycyrrhiza yunnanensis Roots." Planta medica vol. 57,2 (1991): 165-8. doi: https://doi.org/10.1055/s-2006-960057
Zeng L, Zhang RY, Wang D, Zhang ZL, Lou ZC. Glyyunnansapogenins G and H: Two New Pentacyclic Triterpenoids of the 18alphaH-Oleana-9(11),12-diene Type from Glycyrrhiza yunnanensis Roots. Planta Med. 1991 Apr;57(2):165-8. doi: 10.1055/s-2006-960057. PMID: 17226143.
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Steroidal alkaloids in tissue cultures and regenerated plants of Solanum dulcamara.

Plant cell reports

Emke A, Eilert U.
PMID: 24247961
Plant Cell Rep. 1986 Feb;5(1):31-4. doi: 10.1007/BF00269712.

Callus and cell suspension cultures were established with shoots of the soladulcidine variety of the bittersweet Solanum dulcamara L. Plantlets were regenerated from undifferentiated callus. From mixotrophic callus as well as mixotrophic suspension cultures soladulicidine, solasodine and the corresponding...

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Emke A, Eilert U. Steroidal alkaloids in tissue cultures and regenerated plants of Solanum dulcamara. Plant Cell Rep. 1986;5(1):31-4doi: 10.1007/BF00269712.
Emke, A., & Eilert, U. (1986). Steroidal alkaloids in tissue cultures and regenerated plants of Solanum dulcamara. Plant cell reports, 5(1), 31-4. https://doi.org/10.1007/BF00269712
Emke, A, and Eilert, U. "Steroidal alkaloids in tissue cultures and regenerated plants of Solanum dulcamara." Plant cell reports vol. 5,1 (1986): 31-4. doi: https://doi.org/10.1007/BF00269712
Emke A, Eilert U. Steroidal alkaloids in tissue cultures and regenerated plants of Solanum dulcamara. Plant Cell Rep. 1986 Feb;5(1):31-4. doi: 10.1007/BF00269712. PMID: 24247961.
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Liquid Chromatography Mass Spectrometry Analysis and Cytotoxicity of .

Pharmacognosy magazine

Khan KM, Nahar L, Mannan A, Arfan M, Khan GA, Al-Groshi A, Evans A, Dempster NM, Ismail FMD, Sarker SD.
PMID: 29491650
Pharmacogn Mag. 2018 Jan;13:S890-S894. doi: 10.4103/pm.pm_136_17. Epub 2018 Jan 31.

OBJECTIVE: This paper reports, for the first time, on the cytotoxicity of the methanol (MeOH) extract of the roots of MATERIALS AND METHODS: Finely powdered roots of RESULTS: The MeOH extract and four SPE fractions exhibited cytotoxicity against all...

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Khan KM, Nahar L, Mannan A, et al. Liquid Chromatography Mass Spectrometry Analysis and Cytotoxicity of . Pharmacogn Mag. 2018;13:S890-S894doi: 10.4103/pm.pm_136_17.
Khan, K. M., Nahar, L., Mannan, A., Arfan, M., Khan, G. A., Al-Groshi, A., Evans, A., Dempster, N. M., Ismail, F. M. D., & Sarker, S. D. (2018). Liquid Chromatography Mass Spectrometry Analysis and Cytotoxicity of . Pharmacognosy magazine, 13S890-S894. https://doi.org/10.4103/pm.pm_136_17
Khan, Kashif Maqbool, et al. "Liquid Chromatography Mass Spectrometry Analysis and Cytotoxicity of ." Pharmacognosy magazine vol. 13 (2018): S890-S894. doi: https://doi.org/10.4103/pm.pm_136_17
Khan KM, Nahar L, Mannan A, Arfan M, Khan GA, Al-Groshi A, Evans A, Dempster NM, Ismail FMD, Sarker SD. Liquid Chromatography Mass Spectrometry Analysis and Cytotoxicity of . Pharmacogn Mag. 2018 Jan;13:S890-S894. doi: 10.4103/pm.pm_136_17. Epub 2018 Jan 31. PMID: 29491650; PMCID: PMC5822517.
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Antioxidative enzymes activities and accumulation of steroids in hairy roots of .

Physiology and molecular biology of plants : an international journal of functional plant biology

Kohsari S, Rezayian M, Niknam V, Mirmasoumi M.
PMID: 32158135
Physiol Mol Biol Plants. 2020 Feb;26(2):281-288. doi: 10.1007/s12298-019-00753-6. Epub 2020 Jan 21.

Steroidal sapogenins and phytosterols are a group of secondary metabolites which are very considerable in the pharmaceutical industry. Fenugreek (

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Kohsari S, Rezayian M, Niknam V, et al. Antioxidative enzymes activities and accumulation of steroids in hairy roots of . Physiol Mol Biol Plants. 2020;26(2):281-288doi: 10.1007/s12298-019-00753-6.
Kohsari, S., Rezayian, M., Niknam, V., & Mirmasoumi, M. (2020). Antioxidative enzymes activities and accumulation of steroids in hairy roots of . Physiology and molecular biology of plants : an international journal of functional plant biology, 26(2), 281-288. https://doi.org/10.1007/s12298-019-00753-6
Kohsari, Somayeh, et al. "Antioxidative enzymes activities and accumulation of steroids in hairy roots of ." Physiology and molecular biology of plants : an international journal of functional plant biology vol. 26,2 (2020): 281-288. doi: https://doi.org/10.1007/s12298-019-00753-6
Kohsari S, Rezayian M, Niknam V, Mirmasoumi M. Antioxidative enzymes activities and accumulation of steroids in hairy roots of . Physiol Mol Biol Plants. 2020 Feb;26(2):281-288. doi: 10.1007/s12298-019-00753-6. Epub 2020 Jan 21. PMID: 32158135; PMCID: PMC7036396.
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Targeting autophagy using saponins as a therapeutic and preventive strategy against human diseases.

Pharmacological research

Han B, He C.
PMID: 33540047
Pharmacol Res. 2021 Apr;166:105428. doi: 10.1016/j.phrs.2021.105428. Epub 2021 Feb 01.

Autophagy is a ubiquitous mechanism for maintaining cellular homeostasis through the degradation of long-lived proteins, insoluble protein aggregates, and superfluous or damaged organelles. Dysfunctional autophagy is observed in a variety of human diseases. With advanced research into the role...

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Han B, He C. Targeting autophagy using saponins as a therapeutic and preventive strategy against human diseases. Pharmacol Res. 2021;166:105428doi: 10.1016/j.phrs.2021.105428.
Han, B., & He, C. (2021). Targeting autophagy using saponins as a therapeutic and preventive strategy against human diseases. Pharmacological research, 166105428. https://doi.org/10.1016/j.phrs.2021.105428
Han, Bing, and He, Chengwei. "Targeting autophagy using saponins as a therapeutic and preventive strategy against human diseases." Pharmacological research vol. 166 (2021): 105428. doi: https://doi.org/10.1016/j.phrs.2021.105428
Han B, He C. Targeting autophagy using saponins as a therapeutic and preventive strategy against human diseases. Pharmacol Res. 2021 Apr;166:105428. doi: 10.1016/j.phrs.2021.105428. Epub 2021 Feb 01. PMID: 33540047.
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Two new steroidal sapogenins from .

Journal of Asian natural products research

Yao SF, Zhang HB, Cai ZS, Gao H, Wang D, Shang SB.
PMID: 33583288
J Asian Nat Prod Res. 2022 Feb;24(2):153-162. doi: 10.1080/10286020.2021.1886088. Epub 2021 Feb 15.

Two novel acylated steroidal sapogenins, 3

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Yao SF, Zhang HB, Cai ZS, et al. Two new steroidal sapogenins from . J Asian Nat Prod Res. 2021;24(2):153-162doi: 10.1080/10286020.2021.1886088.
Yao, S. F., Zhang, H. B., Cai, Z. S., Gao, H., Wang, D., & Shang, S. B. (2022). Two new steroidal sapogenins from . Journal of Asian natural products research, 24(2), 153-162. https://doi.org/10.1080/10286020.2021.1886088
Yao, Shu-Feng, et al. "Two new steroidal sapogenins from ." Journal of Asian natural products research vol. 24,2 (2022): 153-162. doi: https://doi.org/10.1080/10286020.2021.1886088
Yao SF, Zhang HB, Cai ZS, Gao H, Wang D, Shang SB. Two new steroidal sapogenins from . J Asian Nat Prod Res. 2022 Feb;24(2):153-162. doi: 10.1080/10286020.2021.1886088. Epub 2021 Feb 15. PMID: 33583288.
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Dammarane Sapogenins Improving Simulated Weightlessness-Induced Depressive-Like Behaviors and Cognitive Dysfunction in Rats.

Frontiers in psychiatry

Wang Q, Dong L, Wang M, Chen S, Li S, Chen Y, He W, Zhang H, Zhang Y, Pires Dias AC, Yang S, Liu X.
PMID: 33841208
Front Psychiatry. 2021 Mar 26;12:638328. doi: 10.3389/fpsyt.2021.638328. eCollection 2021.

No abstract available.

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Wang Q, Dong L, Wang M, et al. Dammarane Sapogenins Improving Simulated Weightlessness-Induced Depressive-Like Behaviors and Cognitive Dysfunction in Rats. Front Psychiatry. 2021;12:638328doi: 10.3389/fpsyt.2021.638328.
Wang, Q., Dong, L., Wang, M., Chen, S., Li, S., Chen, Y., He, W., Zhang, H., Zhang, Y., Pires Dias, A. C., Yang, S., & Liu, X. (2021). Dammarane Sapogenins Improving Simulated Weightlessness-Induced Depressive-Like Behaviors and Cognitive Dysfunction in Rats. Frontiers in psychiatry, 12638328. https://doi.org/10.3389/fpsyt.2021.638328
Wang, Qiong, et al. "Dammarane Sapogenins Improving Simulated Weightlessness-Induced Depressive-Like Behaviors and Cognitive Dysfunction in Rats." Frontiers in psychiatry vol. 12 (2021): 638328. doi: https://doi.org/10.3389/fpsyt.2021.638328
Wang Q, Dong L, Wang M, Chen S, Li S, Chen Y, He W, Zhang H, Zhang Y, Pires Dias AC, Yang S, Liu X. Dammarane Sapogenins Improving Simulated Weightlessness-Induced Depressive-Like Behaviors and Cognitive Dysfunction in Rats. Front Psychiatry. 2021 Mar 26;12:638328. doi: 10.3389/fpsyt.2021.638328. eCollection 2021. PMID: 33841208; PMCID: PMC8032884.
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Analysis of saponin composition and comparison of the antioxidant activity of various parts of the quinoa plant (.

Food science & nutrition

Lim JG, Park HM, Yoon KS.
PMID: 31993193
Food Sci Nutr. 2019 Dec 19;8(1):694-702. doi: 10.1002/fsn3.1358. eCollection 2020 Jan.

Quinoa plant is a valuable food crop because of its high nutritional and functional values. Total saponin content, sapogenins, polyphenol, and flavonoid contents and antioxidant activities were analyzed in various parts of quinoa plants, including sprout, seeds, bran, pericarp,...

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Lim JG, Park HM, Yoon KS. Analysis of saponin composition and comparison of the antioxidant activity of various parts of the quinoa plant (. Food Sci Nutr. 2019;8(1):694-702doi: 10.1002/fsn3.1358.
Lim, J. G., Park, H. M., & Yoon, K. S. (2020). Analysis of saponin composition and comparison of the antioxidant activity of various parts of the quinoa plant (. Food science & nutrition, 8(1), 694-702. https://doi.org/10.1002/fsn3.1358
Lim, Jeong Gyu, et al. "Analysis of saponin composition and comparison of the antioxidant activity of various parts of the quinoa plant (." Food science & nutrition vol. 8,1 (2020): 694-702. doi: https://doi.org/10.1002/fsn3.1358
Lim JG, Park HM, Yoon KS. Analysis of saponin composition and comparison of the antioxidant activity of various parts of the quinoa plant (. Food Sci Nutr. 2019 Dec 19;8(1):694-702. doi: 10.1002/fsn3.1358. eCollection 2020 Jan. PMID: 31993193; PMCID: PMC6977472.
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Hemolytic and cytotoxic properties of saponin purified from Holothuria leucospilota sea cucumber.

Reports of biochemistry & molecular biology

Soltani M, Parivar K, Baharara J, Kerachian MA, Asili J.
PMID: 26989736
Rep Biochem Mol Biol. 2014 Oct;3(1):43-50.

BACKGROUND: Holothuroids (sea cucumbers) are members of the phylum echinodermata, which produce saponins. Saponins exhibit a wide spectrum of pharmacological and biological activities. In this study, we isolated the crude saponins from the body wall of the dominant Iranian...

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Soltani M, Parivar K, Baharara J, et al. Hemolytic and cytotoxic properties of saponin purified from Holothuria leucospilota sea cucumber. Rep Biochem Mol Biol. 2014;3(1):43-50
Soltani, M., Parivar, K., Baharara, J., Kerachian, M. A., & Asili, J. (2014). Hemolytic and cytotoxic properties of saponin purified from Holothuria leucospilota sea cucumber. Reports of biochemistry & molecular biology, 3(1), 43-50.
Soltani, Mozhgan, et al. "Hemolytic and cytotoxic properties of saponin purified from Holothuria leucospilota sea cucumber." Reports of biochemistry & molecular biology vol. 3,1 (2014): 43-50.
Soltani M, Parivar K, Baharara J, Kerachian MA, Asili J. Hemolytic and cytotoxic properties of saponin purified from Holothuria leucospilota sea cucumber. Rep Biochem Mol Biol. 2014 Oct;3(1):43-50. PMID: 26989736; PMCID: PMC4757088.
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High-performance liquid chromatography analysis of plant saponins: An update 2005-2010.

Pharmacognosy reviews

Negi JS, Singh P, Pant GJ, Rawat MS.
PMID: 22303089
Pharmacogn Rev. 2011 Jul;5(10):155-8. doi: 10.4103/0973-7847.91109.

Saponins are widely distributed in plant kingdom. In view of their wide range of biological activities and occurrence as complex mixtures, saponins have been purified and separated by high-performance liquid chromatography using reverse-phase columns at lower wavelength. Mostly, saponins...

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Negi JS, Singh P, Pant GJ, et al. High-performance liquid chromatography analysis of plant saponins: An update 2005-2010. Pharmacogn Rev. 2011;5(10):155-8doi: 10.4103/0973-7847.91109.
Negi, J. S., Singh, P., Pant, G. J., & Rawat, M. S. (2011). High-performance liquid chromatography analysis of plant saponins: An update 2005-2010. Pharmacognosy reviews, 5(10), 155-8. https://doi.org/10.4103/0973-7847.91109
Negi, Jagmohan S, et al. "High-performance liquid chromatography analysis of plant saponins: An update 2005-2010." Pharmacognosy reviews vol. 5,10 (2011): 155-8. doi: https://doi.org/10.4103/0973-7847.91109
Negi JS, Singh P, Pant GJ, Rawat MS. High-performance liquid chromatography analysis of plant saponins: An update 2005-2010. Pharmacogn Rev. 2011 Jul;5(10):155-8. doi: 10.4103/0973-7847.91109. PMID: 22303089; PMCID: PMC3263049.
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Showing 1 to 12 of 38 entries