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Synthesis of new xanthenone derivatives of expected antibilharzial activity.

Archives of pharmacal research

Omar MT.
PMID: 18982267
Arch Pharm Res. 1997 Dec;20(6):602-9. doi: 10.1007/BF02975219.

A new series of 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles incorporated directly and/or indirectly into a xanthenone moiety at position-2 were synthesized. Some of the newly prepared compounds were biologically tested as schistosomicides in experimental animals.

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Omar MT. Synthesis of new xanthenone derivatives of expected antibilharzial activity. Arch Pharm Res. 1997;20(6):602-9doi: 10.1007/BF02975219.
Omar, M. T. (1997). Synthesis of new xanthenone derivatives of expected antibilharzial activity. Archives of pharmacal research, 20(6), 602-9. https://doi.org/10.1007/BF02975219
Omar, M T. "Synthesis of new xanthenone derivatives of expected antibilharzial activity." Archives of pharmacal research vol. 20,6 (1997): 602-9. doi: https://doi.org/10.1007/BF02975219
Omar MT. Synthesis of new xanthenone derivatives of expected antibilharzial activity. Arch Pharm Res. 1997 Dec;20(6):602-9. doi: 10.1007/BF02975219. PMID: 18982267.
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Chemotherapy for human schistosomiasis: how far have we come? What's new? Where do we go from here?.

RSC medicinal chemistry

Dziwornu GA, Attram HD, Gachuhi S, Chibale K.
PMID: 33479649
RSC Med Chem. 2020 Apr 06;11(4):455-490. doi: 10.1039/d0md00062k. eCollection 2020 Apr 01.

Globally, schistosomiasis threatens more than 700 million lives, mostly children, in poor localities of tropical and sub-tropical areas with morbidity due to acute and chronic pathological manifestations of the disease. After a century since the first antimonial-based drugs were...

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Dziwornu GA, Attram HD, Gachuhi S, et al. Chemotherapy for human schistosomiasis: how far have we come? What's new? Where do we go from here?. RSC Med Chem. 2020;11(4):455-490doi: 10.1039/d0md00062k.
Dziwornu, G. A., Attram, H. D., Gachuhi, S., & Chibale, K. (2020). Chemotherapy for human schistosomiasis: how far have we come? What's new? Where do we go from here?. RSC medicinal chemistry, 11(4), 455-490. https://doi.org/10.1039/d0md00062k
Dziwornu, Godwin Akpeko, et al. "Chemotherapy for human schistosomiasis: how far have we come? What's new? Where do we go from here?." RSC medicinal chemistry vol. 11,4 (2020): 455-490. doi: https://doi.org/10.1039/d0md00062k
Dziwornu GA, Attram HD, Gachuhi S, Chibale K. Chemotherapy for human schistosomiasis: how far have we come? What's new? Where do we go from here?. RSC Med Chem. 2020 Apr 06;11(4):455-490. doi: 10.1039/d0md00062k. eCollection 2020 Apr 01. PMID: 33479649; PMCID: PMC7593896.
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Antischistosomal therapy: Current status and recent developments.

Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology

Esmat G, Raziky ME.
PMID: 24842128
Arab J Gastroenterol. 2009 Mar;10(1):1-3. doi: 10.1016/j.ajg.2009.03.002. Epub 2009 May 03.

Schistosomiasis remains one of the most prevalent parasitic infections in the world. Currently, Praziquantel (PZQ) is the drug being used to treat human schistosomiasis on a large scale. Millions of people are treated annually with praziquantel, and drug-resistant parasites...

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Esmat G, Raziky ME. Antischistosomal therapy: Current status and recent developments. Arab J Gastroenterol. 2009;10(1):1-3doi: 10.1016/j.ajg.2009.03.002.
Esmat, G., & Raziky, M. E. (2009). Antischistosomal therapy: Current status and recent developments. Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology, 10(1), 1-3. https://doi.org/10.1016/j.ajg.2009.03.002
Esmat, Gamal, and Raziky, Maissa El. "Antischistosomal therapy: Current status and recent developments." Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology vol. 10,1 (2009): 1-3. doi: https://doi.org/10.1016/j.ajg.2009.03.002
Esmat G, Raziky ME. Antischistosomal therapy: Current status and recent developments. Arab J Gastroenterol. 2009 Mar;10(1):1-3. doi: 10.1016/j.ajg.2009.03.002. Epub 2009 May 03. PMID: 24842128.
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Novel therapeutic and prevention approaches for schistosomiasis: review.

Journal of advanced research

El Ridi RA, Tallima HA.
PMID: 25685454
J Adv Res. 2013 Sep;4(5):467-78. doi: 10.1016/j.jare.2012.05.002. Epub 2012 Jun 23.

Schistosomiasis is a debilitating disease affecting approximately 600 million people in 74 developing countries, with 800 million, mostly children at risk. To circumvent the threat of having praziquantel (PZQ) as the only drug used for treatment, several PZQ derivatives...

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El Ridi RA, Tallima HA. Novel therapeutic and prevention approaches for schistosomiasis: review. J Adv Res. 2012;4(5):467-78doi: 10.1016/j.jare.2012.05.002.
El Ridi, R. A., & Tallima, H. A. (2013). Novel therapeutic and prevention approaches for schistosomiasis: review. Journal of advanced research, 4(5), 467-78. https://doi.org/10.1016/j.jare.2012.05.002
El Ridi, Rashika A F, and Tallima, Hatem A-M. "Novel therapeutic and prevention approaches for schistosomiasis: review." Journal of advanced research vol. 4,5 (2013): 467-78. doi: https://doi.org/10.1016/j.jare.2012.05.002
El Ridi RA, Tallima HA. Novel therapeutic and prevention approaches for schistosomiasis: review. J Adv Res. 2013 Sep;4(5):467-78. doi: 10.1016/j.jare.2012.05.002. Epub 2012 Jun 23. PMID: 25685454; PMCID: PMC4293887.
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Exposure to hycanthone alters chromatin structure around specific gene functions and specific repeats in Schistosoma mansoni.

Frontiers in genetics

Roquis D, Lepesant JM, Villafan E, Boissier J, Vieira C, Cosseau C, Grunau C.
PMID: 25076965
Front Genet. 2014 Jul 16;5:207. doi: 10.3389/fgene.2014.00207. eCollection 2014.

Schistosoma mansoni is a parasitic plathyhelminth responsible for intestinal schistosomiasis (or bilharzia), a disease affecting 67 million people worldwide and causing an important economic burden. The schistosomicides hycanthone, and its later proxy oxamniquine, were widely used for treatments in...

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Roquis D, Lepesant JM, Villafan E, et al. Exposure to hycanthone alters chromatin structure around specific gene functions and specific repeats in Schistosoma mansoni. Front Genet. 2014;5:207doi: 10.3389/fgene.2014.00207.
Roquis, D., Lepesant, J. M., Villafan, E., Boissier, J., Vieira, C., Cosseau, C., & Grunau, C. (2014). Exposure to hycanthone alters chromatin structure around specific gene functions and specific repeats in Schistosoma mansoni. Frontiers in genetics, 5207. https://doi.org/10.3389/fgene.2014.00207
Roquis, David, et al. "Exposure to hycanthone alters chromatin structure around specific gene functions and specific repeats in Schistosoma mansoni." Frontiers in genetics vol. 5 (2014): 207. doi: https://doi.org/10.3389/fgene.2014.00207
Roquis D, Lepesant JM, Villafan E, Boissier J, Vieira C, Cosseau C, Grunau C. Exposure to hycanthone alters chromatin structure around specific gene functions and specific repeats in Schistosoma mansoni. Front Genet. 2014 Jul 16;5:207. doi: 10.3389/fgene.2014.00207. eCollection 2014. PMID: 25076965; PMCID: PMC4099960.
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Editorial: Pre-Conference Research Topic: 16th International Symposium on Schistosomiasis.

Frontiers in immunology

Fonseca CT, Pereira TA, Stothard JR, Caldeira RL, Mourão MM.
PMID: 34899729
Front Immunol. 2021 Nov 25;12:774311. doi: 10.3389/fimmu.2021.774311. eCollection 2021.

No abstract available.

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Fonseca CT, Pereira TA, Stothard JR, et al. Editorial: Pre-Conference Research Topic: 16th International Symposium on Schistosomiasis. Front Immunol. 2021;12:774311doi: 10.3389/fimmu.2021.774311.
Fonseca, C. T., Pereira, T. A., Stothard, J. R., Caldeira, R. L., & Mourão, M. M. (2021). Editorial: Pre-Conference Research Topic: 16th International Symposium on Schistosomiasis. Frontiers in immunology, 12774311. https://doi.org/10.3389/fimmu.2021.774311
Fonseca, Cristina Toscano, et al. "Editorial: Pre-Conference Research Topic: 16th International Symposium on Schistosomiasis." Frontiers in immunology vol. 12 (2021): 774311. doi: https://doi.org/10.3389/fimmu.2021.774311
Fonseca CT, Pereira TA, Stothard JR, Caldeira RL, Mourão MM. Editorial: Pre-Conference Research Topic: 16th International Symposium on Schistosomiasis. Front Immunol. 2021 Nov 25;12:774311. doi: 10.3389/fimmu.2021.774311. eCollection 2021. PMID: 34899729; PMCID: PMC8656701.
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Editorial: Pre-Conference Research Topic: 16th International Symposium on Schistosomiasis.

Frontiers in immunology

Fonseca CT, Pereira TA, Stothard JR, Caldeira RL, Mourão MM.
PMID: 34899729
Front Immunol. 2021 Nov 25;12:774311. doi: 10.3389/fimmu.2021.774311. eCollection 2021.

No abstract available.

Cite
Fonseca CT, Pereira TA, Stothard JR, et al. Editorial: Pre-Conference Research Topic: 16th International Symposium on Schistosomiasis. Front Immunol. 2021;12:774311doi: 10.3389/fimmu.2021.774311.
Fonseca, C. T., Pereira, T. A., Stothard, J. R., Caldeira, R. L., & Mourão, M. M. (2021). Editorial: Pre-Conference Research Topic: 16th International Symposium on Schistosomiasis. Frontiers in immunology, 12774311. https://doi.org/10.3389/fimmu.2021.774311
Fonseca, Cristina Toscano, et al. "Editorial: Pre-Conference Research Topic: 16th International Symposium on Schistosomiasis." Frontiers in immunology vol. 12 (2021): 774311. doi: https://doi.org/10.3389/fimmu.2021.774311
Fonseca CT, Pereira TA, Stothard JR, Caldeira RL, Mourão MM. Editorial: Pre-Conference Research Topic: 16th International Symposium on Schistosomiasis. Front Immunol. 2021 Nov 25;12:774311. doi: 10.3389/fimmu.2021.774311. eCollection 2021. PMID: 34899729; PMCID: PMC8656701.
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