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Age-related changes in the lateral lipid distribution in a human lens described by mass spectrometry imaging.

European journal of mass spectrometry (Chichester, England)

Pol J, Faltyskova H, Krasny L, Volný M, Vlacil O, Hajduch M, Lemr K, Havlicek V.
PMID: 26307709
Eur J Mass Spectrom (Chichester). 2015;21(3):297-303. doi: 10.1255/ejms.1350.

The lateral lipid distribution in eye lenses of three human donors were studied by matrix-assisted laser desorption ionization imaging mass spectrometry using a high mass resolution. By using exact mass measurements this study shows the relationship between the aging...

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Pol J, Faltyskova H, Krasny L, et al. Age-related changes in the lateral lipid distribution in a human lens described by mass spectrometry imaging. Eur J Mass Spectrom (Chichester). 2015;21(3):297-303doi: 10.1255/ejms.1350.
Pol, J., Faltyskova, H., Krasny, L., Volný, M., Vlacil, O., Hajduch, M., Lemr, K., & Havlicek, V. (2015). Age-related changes in the lateral lipid distribution in a human lens described by mass spectrometry imaging. European journal of mass spectrometry (Chichester, England), 21(3), 297-303. https://doi.org/10.1255/ejms.1350
Pol, Jaroslav, et al. "Age-related changes in the lateral lipid distribution in a human lens described by mass spectrometry imaging." European journal of mass spectrometry (Chichester, England) vol. 21,3 (2015): 297-303. doi: https://doi.org/10.1255/ejms.1350
Pol J, Faltyskova H, Krasny L, Volný M, Vlacil O, Hajduch M, Lemr K, Havlicek V. Age-related changes in the lateral lipid distribution in a human lens described by mass spectrometry imaging. Eur J Mass Spectrom (Chichester). 2015;21(3):297-303. doi: 10.1255/ejms.1350. PMID: 26307709.
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Impact of nutrient excess and endothelial nitric oxide synthase on the plasma metabolite profile in mice.

Frontiers in physiology

Sansbury BE, Bhatnagar A, Hill BG.
PMID: 25505420
Front Physiol. 2014 Nov 25;5:453. doi: 10.3389/fphys.2014.00453. eCollection 2014.

An increase in calorie consumption is associated with the recent rise in obesity prevalence. However, our current understanding of the effects of nutrient excess on major metabolic pathways appears insufficient to develop safe and effective metabolic interventions to prevent...

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Sansbury BE, Bhatnagar A, Hill BG. Impact of nutrient excess and endothelial nitric oxide synthase on the plasma metabolite profile in mice. Front Physiol. 2014;5:453doi: 10.3389/fphys.2014.00453.
Sansbury, B. E., Bhatnagar, A., & Hill, B. G. (2014). Impact of nutrient excess and endothelial nitric oxide synthase on the plasma metabolite profile in mice. Frontiers in physiology, 5453. https://doi.org/10.3389/fphys.2014.00453
Sansbury, Brian E, et al. "Impact of nutrient excess and endothelial nitric oxide synthase on the plasma metabolite profile in mice." Frontiers in physiology vol. 5 (2014): 453. doi: https://doi.org/10.3389/fphys.2014.00453
Sansbury BE, Bhatnagar A, Hill BG. Impact of nutrient excess and endothelial nitric oxide synthase on the plasma metabolite profile in mice. Front Physiol. 2014 Nov 25;5:453. doi: 10.3389/fphys.2014.00453. eCollection 2014. PMID: 25505420; PMCID: PMC4243488.
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Distribution of Presenilins and Amyloid Precursor Protein (APP) in Detergent-Insoluble Membrane Domains.

Methods in molecular medicine

Parkin ET, Turner AJ, Hooper NM.
PMID: 21318531
Methods Mol Med. 2000;32:345-60. doi: 10.1385/1-59259-195-7:345.

Until recently, the detergent insolubility of certain membrane-associated proteins was singularly attributed to an association with the cytoskeleton. However, in 1988 we observed that a number of glycosyl-phosphatidylinositol (GPI)-anchored proteins were resistant to solubilization by nonionic detergents such as...

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Parkin ET, Turner AJ, Hooper NM. Distribution of Presenilins and Amyloid Precursor Protein (APP) in Detergent-Insoluble Membrane Domains. Methods Mol Med. 2000;32:345-60doi: 10.1385/1-59259-195-7:345.
Parkin, E. T., Turner, A. J., & Hooper, N. M. (2000). Distribution of Presenilins and Amyloid Precursor Protein (APP) in Detergent-Insoluble Membrane Domains. Methods in molecular medicine, 32345-60. https://doi.org/10.1385/1-59259-195-7:345
Parkin, E T, et al. "Distribution of Presenilins and Amyloid Precursor Protein (APP) in Detergent-Insoluble Membrane Domains." Methods in molecular medicine vol. 32 (2000): 345-60. doi: https://doi.org/10.1385/1-59259-195-7:345
Parkin ET, Turner AJ, Hooper NM. Distribution of Presenilins and Amyloid Precursor Protein (APP) in Detergent-Insoluble Membrane Domains. Methods Mol Med. 2000;32:345-60. doi: 10.1385/1-59259-195-7:345. PMID: 21318531.
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UPLC-QTOF/MS-Based Lipidomic Profiling of Liver Qi-Stagnation and Spleen-Deficiency Syndrome in Patients with Hyperlipidemia.

Evidence-based complementary and alternative medicine : eCAM

Shenghua P, Shuyu T, Kunping L, Huixia Z, Xue X, Jiao G.
PMID: 30245731
Evid Based Complement Alternat Med. 2018 Aug 30;2018:4530849. doi: 10.1155/2018/4530849. eCollection 2018.

Hyperlipidemia is a common disease caused by abnormal plasma lipid metabolism. Lipidomics is a powerful and efficient technology to study the integration of disease and syndrome of Chinese medicine. This study investigated specific changes in lipid metabolites from hyperlipidemia...

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Shenghua P, Shuyu T, Kunping L, et al. UPLC-QTOF/MS-Based Lipidomic Profiling of Liver Qi-Stagnation and Spleen-Deficiency Syndrome in Patients with Hyperlipidemia. Evid Based Complement Alternat Med. 2018;2018:4530849doi: 10.1155/2018/4530849.
Shenghua, P., Shuyu, T., Kunping, L., Huixia, Z., Xue, X., & Jiao, G. (2018). UPLC-QTOF/MS-Based Lipidomic Profiling of Liver Qi-Stagnation and Spleen-Deficiency Syndrome in Patients with Hyperlipidemia. Evidence-based complementary and alternative medicine : eCAM, 20184530849. https://doi.org/10.1155/2018/4530849
Shenghua, Piao, et al. "UPLC-QTOF/MS-Based Lipidomic Profiling of Liver Qi-Stagnation and Spleen-Deficiency Syndrome in Patients with Hyperlipidemia." Evidence-based complementary and alternative medicine : eCAM vol. 2018 (2018): 4530849. doi: https://doi.org/10.1155/2018/4530849
Shenghua P, Shuyu T, Kunping L, Huixia Z, Xue X, Jiao G. UPLC-QTOF/MS-Based Lipidomic Profiling of Liver Qi-Stagnation and Spleen-Deficiency Syndrome in Patients with Hyperlipidemia. Evid Based Complement Alternat Med. 2018 Aug 30;2018:4530849. doi: 10.1155/2018/4530849. eCollection 2018. PMID: 30245731; PMCID: PMC6136559.
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Lipidomic Evaluation of Feline Neurologic Disease after AAV Gene Therapy.

Molecular therapy. Methods & clinical development

Gray-Edwards HL, Jiang X, Randle AN, Taylor AR, Voss TL, Johnson AK, McCurdy VJ, Sena-Esteves M, Ory DS, Martin DR.
PMID: 28808666
Mol Ther Methods Clin Dev. 2017 Jul 26;6:135-142. doi: 10.1016/j.omtm.2017.07.005. eCollection 2017 Sep 15.

GM1 gangliosidosis is a fatal lysosomal disorder, for which there is no effective treatment. Adeno-associated virus (AAV) gene therapy in GM1 cats has resulted in a greater than 6-fold increase in lifespan, with many cats remaining alive at >5.7...

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Gray-Edwards HL, Jiang X, Randle AN, et al. Lipidomic Evaluation of Feline Neurologic Disease after AAV Gene Therapy. Mol Ther Methods Clin Dev. 2017;6:135-142doi: 10.1016/j.omtm.2017.07.005.
Gray-Edwards, H. L., Jiang, X., Randle, A. N., Taylor, A. R., Voss, T. L., Johnson, A. K., McCurdy, V. J., Sena-Esteves, M., Ory, D. S., & Martin, D. R. (2017). Lipidomic Evaluation of Feline Neurologic Disease after AAV Gene Therapy. Molecular therapy. Methods & clinical development, 6135-142. https://doi.org/10.1016/j.omtm.2017.07.005
Gray-Edwards, Heather L, et al. "Lipidomic Evaluation of Feline Neurologic Disease after AAV Gene Therapy." Molecular therapy. Methods & clinical development vol. 6 (2017): 135-142. doi: https://doi.org/10.1016/j.omtm.2017.07.005
Gray-Edwards HL, Jiang X, Randle AN, Taylor AR, Voss TL, Johnson AK, McCurdy VJ, Sena-Esteves M, Ory DS, Martin DR. Lipidomic Evaluation of Feline Neurologic Disease after AAV Gene Therapy. Mol Ther Methods Clin Dev. 2017 Jul 26;6:135-142. doi: 10.1016/j.omtm.2017.07.005. eCollection 2017 Sep 15. PMID: 28808666; PMCID: PMC5545771.
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Data on metabolomic profiling of ovarian cancer patients' serum for potential diagnostic biomarkers.

Data in brief

Kozar N, Kruusmaa K, Bitenc M, Argamasilla R, Adsuar A, Goswami N, Arko D, Takač I.
PMID: 29904684
Data Brief. 2018 Apr 30;18:1825-1831. doi: 10.1016/j.dib.2018.04.081. eCollection 2018 Jun.

The data presented here are related to the research paper entitled "Metabolomic profiling suggests long chain ceramides and sphingomyelins as a possible diagnostic biomarker of epithelial ovarian cancer." (Kozar et al., 2018) [1]. Metabolomic profiling was performed on 15...

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Kozar N, Kruusmaa K, Bitenc M, et al. Data on metabolomic profiling of ovarian cancer patients' serum for potential diagnostic biomarkers. Data Brief. 2018;18:1825-1831doi: 10.1016/j.dib.2018.04.081.
Kozar, N., Kruusmaa, K., Bitenc, M., Argamasilla, R., Adsuar, A., Goswami, N., Arko, D., & Takač, I. (2018). Data on metabolomic profiling of ovarian cancer patients' serum for potential diagnostic biomarkers. Data in brief, 181825-1831. https://doi.org/10.1016/j.dib.2018.04.081
Kozar, Nejc, et al. "Data on metabolomic profiling of ovarian cancer patients' serum for potential diagnostic biomarkers." Data in brief vol. 18 (2018): 1825-1831. doi: https://doi.org/10.1016/j.dib.2018.04.081
Kozar N, Kruusmaa K, Bitenc M, Argamasilla R, Adsuar A, Goswami N, Arko D, Takač I. Data on metabolomic profiling of ovarian cancer patients' serum for potential diagnostic biomarkers. Data Brief. 2018 Apr 30;18:1825-1831. doi: 10.1016/j.dib.2018.04.081. eCollection 2018 Jun. PMID: 29904684; PMCID: PMC5998211.
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Sex-Specific Relationship between the Cardiorespiratory Fitness and Plasma Metabolite Patterns in Healthy Humans-Results of the KarMeN Study.

Metabolites

Kistner S, Döring M, Krüger R, Rist MJ, Weinert CH, Bunzel D, Merz B, Radloff K, Neumann R, Härtel S, Bub A.
PMID: 34357357
Metabolites. 2021 Jul 17;11(7). doi: 10.3390/metabo11070463.

Cardiorespiratory fitness (CRF) represents a strong predictor of all-cause mortality and is strongly influenced by regular physical activity (PA). However, the biological mechanisms involved in the body's adaptation to PA remain to be fully elucidated. The aim of this...

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Kistner S, Döring M, Krüger R, et al. Sex-Specific Relationship between the Cardiorespiratory Fitness and Plasma Metabolite Patterns in Healthy Humans-Results of the KarMeN Study. Metabolites. 2021;11(7)doi: 10.3390/metabo11070463.
Kistner, S., Döring, M., Krüger, R., Rist, M. J., Weinert, C. H., Bunzel, D., Merz, B., Radloff, K., Neumann, R., Härtel, S., & Bub, A. (2021). Sex-Specific Relationship between the Cardiorespiratory Fitness and Plasma Metabolite Patterns in Healthy Humans-Results of the KarMeN Study. Metabolites, 11(7), . https://doi.org/10.3390/metabo11070463
Kistner, Sina, et al. "Sex-Specific Relationship between the Cardiorespiratory Fitness and Plasma Metabolite Patterns in Healthy Humans-Results of the KarMeN Study." Metabolites vol. 11,7 (2021). doi: https://doi.org/10.3390/metabo11070463
Kistner S, Döring M, Krüger R, Rist MJ, Weinert CH, Bunzel D, Merz B, Radloff K, Neumann R, Härtel S, Bub A. Sex-Specific Relationship between the Cardiorespiratory Fitness and Plasma Metabolite Patterns in Healthy Humans-Results of the KarMeN Study. Metabolites. 2021 Jul 17;11(7). doi: 10.3390/metabo11070463. PMID: 34357357; PMCID: PMC8303204.
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Plasma triacylglycerols are biomarkers of β-cell function in mice and humans.

Molecular metabolism

Sánchez-Archidona AR, Cruciani-Guglielmacci C, Roujeau C, Wigger L, Lallement J, Denom J, Barovic M, Kassis N, Mehl F, Weitz J, Distler M, Klose C, Simons K, Ibberson M, Solimena M, Magnan C, Thorens B.
PMID: 34634522
Mol Metab. 2021 Oct 09;54:101355. doi: 10.1016/j.molmet.2021.101355. Epub 2021 Oct 09.

OBJECTIVES: To find plasma biomarkers prognostic of type 2 diabetes, which could also inform on pancreatic β-cell deregulations or defects in the function of insulin target tissues.METHODS: We conducted a systems biology approach to characterize the plasma lipidomes of...

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Sánchez-Archidona AR, Cruciani-Guglielmacci C, Roujeau C, et al. Plasma triacylglycerols are biomarkers of β-cell function in mice and humans. Mol Metab. 2021;54:101355doi: 10.1016/j.molmet.2021.101355.
Sánchez-Archidona, A. R., Cruciani-Guglielmacci, C., Roujeau, C., Wigger, L., Lallement, J., Denom, J., Barovic, M., Kassis, N., Mehl, F., Weitz, J., Distler, M., Klose, C., Simons, K., Ibberson, M., Solimena, M., Magnan, C., & Thorens, B. (2021). Plasma triacylglycerols are biomarkers of β-cell function in mice and humans. Molecular metabolism, 54101355. https://doi.org/10.1016/j.molmet.2021.101355
Sánchez-Archidona, Ana Rodríguez, et al. "Plasma triacylglycerols are biomarkers of β-cell function in mice and humans." Molecular metabolism vol. 54 (2021): 101355. doi: https://doi.org/10.1016/j.molmet.2021.101355
Sánchez-Archidona AR, Cruciani-Guglielmacci C, Roujeau C, Wigger L, Lallement J, Denom J, Barovic M, Kassis N, Mehl F, Weitz J, Distler M, Klose C, Simons K, Ibberson M, Solimena M, Magnan C, Thorens B. Plasma triacylglycerols are biomarkers of β-cell function in mice and humans. Mol Metab. 2021 Oct 09;54:101355. doi: 10.1016/j.molmet.2021.101355. Epub 2021 Oct 09. PMID: 34634522; PMCID: PMC8602044.
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Anti-inflammatory and anti-thrombotic properties of lipid bioactives from the entomopathogenic fungus Beauveria bassiana.

Prostaglandins & other lipid mediators

Tsoupras A, Kouvelis VN, Pappas KM, Demopoulos CA, Typas MA.
PMID: 34923152
Prostaglandins Other Lipid Mediat. 2021 Dec 16;158:106606. doi: 10.1016/j.prostaglandins.2021.106606. Epub 2021 Dec 16.

In the present work the entomopathogenic fungus B. bassiana lipids were studied against the potent pro-inflammatory and thrombotic mediators implicated in several disorders, platelet-activating factor (PAF) and thrombin. Bioactivities of lipid extracts from B. bassiana cells and culture supernatants...

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Tsoupras A, Kouvelis VN, Pappas KM, et al. Anti-inflammatory and anti-thrombotic properties of lipid bioactives from the entomopathogenic fungus Beauveria bassiana. Prostaglandins Other Lipid Mediat. 2021;158:106606doi: 10.1016/j.prostaglandins.2021.106606.
Tsoupras, A., Kouvelis, V. N., Pappas, K. M., Demopoulos, C. A., & Typas, M. A. (2021). Anti-inflammatory and anti-thrombotic properties of lipid bioactives from the entomopathogenic fungus Beauveria bassiana. Prostaglandins & other lipid mediators, 158106606. https://doi.org/10.1016/j.prostaglandins.2021.106606
Tsoupras, Alexandros, et al. "Anti-inflammatory and anti-thrombotic properties of lipid bioactives from the entomopathogenic fungus Beauveria bassiana." Prostaglandins & other lipid mediators vol. 158 (2021): 106606. doi: https://doi.org/10.1016/j.prostaglandins.2021.106606
Tsoupras A, Kouvelis VN, Pappas KM, Demopoulos CA, Typas MA. Anti-inflammatory and anti-thrombotic properties of lipid bioactives from the entomopathogenic fungus Beauveria bassiana. Prostaglandins Other Lipid Mediat. 2021 Dec 16;158:106606. doi: 10.1016/j.prostaglandins.2021.106606. Epub 2021 Dec 16. PMID: 34923152.
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Human milk sphingomyelins and metabolomics: an enigma to be discovered.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

Bosco A, Toto M, Pintus R, Fanos V, Dessì A.
PMID: 34362283
J Matern Fetal Neonatal Med. 2021 Aug 06;1-13. doi: 10.1080/14767058.2021.1958314. Epub 2021 Aug 06.

Sphingomyelins, the most abundant sphingolipids in most mammalian cells, appear to be among the most represented polar lipids in breast milk. Despite the variability of the data reported in the literature, human milk sphingomyelins are qualitatively unique and their...

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Bosco A, Toto M, Pintus R, et al. Human milk sphingomyelins and metabolomics: an enigma to be discovered. J Matern Fetal Neonatal Med. 2021;1-13doi: 10.1080/14767058.2021.1958314.
Bosco, A., Toto, M., Pintus, R., Fanos, V., & Dessì, A. (2021). Human milk sphingomyelins and metabolomics: an enigma to be discovered. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 1-13. https://doi.org/10.1080/14767058.2021.1958314
Bosco, Alice, et al. "Human milk sphingomyelins and metabolomics: an enigma to be discovered." The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians vol. (2021): 1-13. doi: https://doi.org/10.1080/14767058.2021.1958314
Bosco A, Toto M, Pintus R, Fanos V, Dessì A. Human milk sphingomyelins and metabolomics: an enigma to be discovered. J Matern Fetal Neonatal Med. 2021 Aug 06;1-13. doi: 10.1080/14767058.2021.1958314. Epub 2021 Aug 06. PMID: 34362283.
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Changes in metabolomics profiles over ten years and subsequent risk of developing type 2 diabetes: Results from the Nurses' Health Study.

EBioMedicine

Wittenbecher C, Guasch-Ferré M, Haslam DE, Dennis C, Li J, Bhupathiraju SN, Lee CH, Qi Q, Liang L, Eliassen AH, Clish C, Sun Q, Hu FB.
PMID: 34979341
EBioMedicine. 2021 Dec 31;75:103799. doi: 10.1016/j.ebiom.2021.103799. Epub 2021 Dec 31.

BACKGROUND: Metabolomics profiles were consistently associated with type 2 diabetes (T2D) risk, but evidence on long-term metabolite changes and T2D incidence is lacking. We examined the associations of 10-year plasma metabolite changes with subsequent T2D risk.METHODS: We conducted a...

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Wittenbecher C, Guasch-Ferré M, Haslam DE, et al. Changes in metabolomics profiles over ten years and subsequent risk of developing type 2 diabetes: Results from the Nurses' Health Study. EBioMedicine. 2021;75:103799doi: 10.1016/j.ebiom.2021.103799.
Wittenbecher, C., Guasch-Ferré, M., Haslam, D. E., Dennis, C., Li, J., Bhupathiraju, S. N., Lee, C. H., Qi, Q., Liang, L., Eliassen, A. H., Clish, C., Sun, Q., & Hu, F. B. (2021). Changes in metabolomics profiles over ten years and subsequent risk of developing type 2 diabetes: Results from the Nurses' Health Study. EBioMedicine, 75103799. https://doi.org/10.1016/j.ebiom.2021.103799
Wittenbecher, Clemens, et al. "Changes in metabolomics profiles over ten years and subsequent risk of developing type 2 diabetes: Results from the Nurses' Health Study." EBioMedicine vol. 75 (2021): 103799. doi: https://doi.org/10.1016/j.ebiom.2021.103799
Wittenbecher C, Guasch-Ferré M, Haslam DE, Dennis C, Li J, Bhupathiraju SN, Lee CH, Qi Q, Liang L, Eliassen AH, Clish C, Sun Q, Hu FB. Changes in metabolomics profiles over ten years and subsequent risk of developing type 2 diabetes: Results from the Nurses' Health Study. EBioMedicine. 2021 Dec 31;75:103799. doi: 10.1016/j.ebiom.2021.103799. Epub 2021 Dec 31. PMID: 34979341; PMCID: PMC8733263.
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Lipidomics reveals association of circulating lipids with body mass index and outcomes in IgA nephropathy patients.

Journal of molecular cell biology

Deng Y, Wu Q, Chen W, Zhu L, Liu W, Xia F, Sun L, Lin X, Zeng R.
PMID: 34272854
J Mol Cell Biol. 2021 Jul 17; doi: 10.1093/jmcb/mjab040. Epub 2021 Jul 17.

IgA nephropathy (IgAN) is a leading cause of chronic kidney disease (CKD), which are commonly accompanied by dyslipidemia. Obesity is also associated with dyslipidemia and risk of CKD, but the relation of the dyslipidemia patterns with obesity and disease...

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Deng Y, Wu Q, Chen W, et al. Lipidomics reveals association of circulating lipids with body mass index and outcomes in IgA nephropathy patients. J Mol Cell Biol. 2021;doi: 10.1093/jmcb/mjab040.
Deng, Y., Wu, Q., Chen, W., Zhu, L., Liu, W., Xia, F., Sun, L., Lin, X., & Zeng, R. (2021). Lipidomics reveals association of circulating lipids with body mass index and outcomes in IgA nephropathy patients. Journal of molecular cell biology, . https://doi.org/10.1093/jmcb/mjab040
Deng, Yueyi, et al. "Lipidomics reveals association of circulating lipids with body mass index and outcomes in IgA nephropathy patients." Journal of molecular cell biology vol. (2021). doi: https://doi.org/10.1093/jmcb/mjab040
Deng Y, Wu Q, Chen W, Zhu L, Liu W, Xia F, Sun L, Lin X, Zeng R. Lipidomics reveals association of circulating lipids with body mass index and outcomes in IgA nephropathy patients. J Mol Cell Biol. 2021 Jul 17; doi: 10.1093/jmcb/mjab040. Epub 2021 Jul 17. PMID: 34272854; PMCID: PMC8697343.
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