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Showing 1 to 12 of 145 entries
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Quality of Sulfadoxine-Pyrimethamine Given as Antimalarial Prophylaxis in Pregnant Women in Selected Health Facilities in Central Region of Ghana.

Journal of parasitology research

Yeboah DF, Afoakwah R, Nwaefuna EK, Verner O, Boampong JN.
PMID: 27042341
J Parasitol Res. 2016;2016:9231946. doi: 10.1155/2016/9231946. Epub 2016 Mar 06.

The use of sulfadoxine-pyrimethamine (SP) as an intermittent preventive treatment (IPT) against malaria during pregnancy has become a policy in most sub-Sahara African countries and crucially depends on the efficacy of SP. This study sets out to evaluate the...

Efficacy of Pyrimethamine/Sulfadoxine versus Chloroquine for the Treatment of Uncomplicated Falciparum Malaria in Children Aged Under 5 Years.

Iranian journal of parasitology

Zheng W, Jiang H, Xiong Z, Jiang Z, Chen H.
PMID: 23682255
Iran J Parasitol. 2013 Jan;8(1):1-17.

The children aged under 5 years from vast African areas badly suffer from falciparum malaria and many of them die of this disease. Therapeutic efficacy of anti-malaria drugs, especially pyrimethamine-sulfadoxine (PS) and chloroquine (CQ) to falciparum malaria is frequently...

Cotrimoxazole in the treatment of acute uncomplicated falciparum malaria in nigerian children : a controlled clinical trial.

Clinical drug investigation

Fehintola FA, Adedeji AA, Tambo E, Fateye BB, Happi TC, Sowunmi A.
PMID: 17516701
Clin Drug Investig. 2004;24(3):149-55. doi: 10.2165/00044011-200424030-00003.

OBJECTIVES: To evaluate the efficacy of cotrimoxazole in the treatment of Plasmodium falciparum malaria and to compare the efficacy of cotrimoxazole with that of pyrimethamine-sulfadoxine, a second-line antimalarial drug, in an area of high malaria transmission.PATIENTS AND METHODS: Children...

Clinical trials of chemotherapy for falciparum malaria.

Expert opinion on investigational drugs

Winstanley P, Olliaro P.
PMID: 15991958
Expert Opin Investig Drugs. 1998 Feb;7(2):261-71. doi: 10.1517/13543784.7.2.261.

Plasmodium falciparum remains one of the World's most prevalent and devastating pathogens. Mainly for economic reasons, the parasite's ability to develop resistance to drugs has not been matched by the rate at which new compounds are developed. Even so,...

New prospects for the treatment of malaria.

Expert opinion on investigational drugs

Winstanley P.
PMID: 15989612
Expert Opin Investig Drugs. 1997 Apr;6(4):447-51. doi: 10.1517/13543784.6.4.447.

This update focuses on drugs for both uncomplicated and severe falciparum malaria. Chloroquine, long the mainstay of therapy, is no longer reliable because of widespread resistance, but is still attractive because of its very low cost. The following strategies...

Availability of antimalarial drugs and evaluation of the attitude and practices for the treatment of uncomplicated malaria in bangui, central african republic.

Journal of tropical medicine

Manirakiza A, Njuimo SP, Le Faou A, Malvy D, Millet P.
PMID: 20339579
J Trop Med. 2010;2010:510834. doi: 10.1155/2010/510834. Epub 2010 Mar 14.

National malaria management policy is based upon the availability of effective and affordable antimalarial drugs. This study was undertaken to evaluate the quality of the treatment of uncomplicated malaria cases in Bangui, an area with multidrug-resistant parasites, at a...

A comparison of trimethoprim-sulfadoxine and ceftiofur sodium for the treatment of respiratory disease in feedlot calves.

The Canadian veterinary journal = La revue veterinaire canadienne

Jim GK, Booker CW, Guichon PT.
PMID: 17423983
Can Vet J. 1992 Apr;33(4):245-50.

A field trial was performed to compare trimethoprim-sulfadoxine to ceftiofur sodium in the treatment of bovine respiratory disease (BRD) in feedlot calves. Five-hundred-and-fifty-five recently weaned, crossbred beef calves, with naturally occurring cases of BRD, were randomly assigned to either...

Randomised controlled trial of weekly chloroquine to re-establish normal erythron iron flux and haemoglobin recovery in postmalarial anaemia.

BMJ open

Cox SE, Nweneka CV, Doherty CP, Fulford AJ, Moore SE, Prentice AM.
PMID: 23833120
BMJ Open. 2013 Jul 04;3(7). doi: 10.1136/bmjopen-2013-002666. Print 2013.

OBJECTIVE: To determine if low-dose weekly chloroquine (CQ) therapy improves recovery from malaria-associated anaemia.DESIGN: Proof of concept randomised clinical trial.SETTING: West Kiang District, Lower River Region, The Gambia.PARTICIPANTS: Children resident in participating communities, aged 12-72 months, with uncomplicated malaria...

Comparative efficacy of uncontrolled and controlled intermittent preventive treatment during pregnancy (IPTp) with combined use of LLTNs in high resistance area to sulfadoxine-pyrimethamine in Côte d'Ivoire.

Infection and drug resistance

Offianan AT, Penali LK, Coulibaly M, Tiacoh N, Ako A, Adji E, Coulibaly B, Koffi D, Sarr D, Jambou R, Kone M.
PMID: 22442633
Infect Drug Resist. 2012;5:53-63. doi: 10.2147/IDR.S27450. Epub 2012 Mar 12.

INTRODUCTION: In recent years, intermittent preventive treatment for pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) has become policy in much of sub-Saharan Africa. But resistance to SP has been spreading across sub-Saharan Africa and thus the effectiveness of IPTp-SP has been...

Effect of iron/folic Acid supplementation on the outcome of malaria episodes treated with sulfadoxine-pyrimethamine.

Malaria research and treatment

Sazawal S, Black RE, Kabole I, Dutta A, Dhingra U, Ramsan M.
PMID: 24575311
Malar Res Treat. 2014;2014:625905. doi: 10.1155/2014/625905. Epub 2014 Jan 19.

Folic acid supplementation may potentially alter the efficacy of sulfadoxine-pyrimethamine (SP) treatment in children with malaria. However, there is lack of evidence from randomized controlled trials and effects of folic acid supplementation on clinical efficacy of SP therapy remain...

Antenatal and delivery care in rural western Kenya: the effect of training health care workers to provide "focused antenatal care".

Reproductive health

Ouma PO, van Eijk AM, Hamel MJ, Sikuku ES, Odhiambo FO, Munguti KM, Ayisi JG, Crawford SB, Kager PA, Slutsker L.
PMID: 20429906
Reprod Health. 2010 Apr 29;7:1. doi: 10.1186/1742-4755-7-1.

BACKGROUND: Maternal mortality remains high in developing countries and data to monitor indicators of progress in maternal care is needed. We examined the status of maternal care before and after health care worker (HCW) training in WHO recommended Focused...

Malaria treatment policy change and implementation: the case of Uganda.

Malaria research and treatment

Nanyunja M, Nabyonga Orem J, Kato F, Kaggwa M, Katureebe C, Saweka J.
PMID: 22312571
Malar Res Treat. 2011;2011:683167. doi: 10.4061/2011/683167. Epub 2011 Sep 19.

Malaria due to P. falciparum is the number one cause of morbidity and mortality in Uganda where it is highly endemic in 95% of the country. The use of efficacious and effective antimalarial medicines is one of the key...

Showing 1 to 12 of 145 entries