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A Randomized Controlled Trial of Lisinopril to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Individuals.

Pathogens & immunity

Cockerham LR, Yukl SA, Harvill K, Somsouk M, Joshi SK, Sinclair E, Liegler T, Hoh R, Lyons S, Hunt PW, Rupert A, Sereti I, Morcock DR, Rhodes A, Emson C, Hellerstein MK, Estes JD, Lewin S, Deeks SG, Hatano H.
PMID: 28936485
Pathog Immun. 2017;2(3):310-334. doi: 10.20411/pai.v2i3.207. Epub 2017 Aug 02.

BACKGROUND: In HIV infection, lymphoid tissue is disrupted by fibrosis. Angiotensin converting enzyme inhibitors have anti-fibrotic properties. We completed a pilot study to assess whether the addition of lisinopril to antiretroviral therapy (ART) reverses fibrosis of gut tissue, and...

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Cockerham LR, Yukl SA, Harvill K, et al. A Randomized Controlled Trial of Lisinopril to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Individuals. Pathog Immun. 2017;2(3):310-334doi: 10.20411/pai.v2i3.207.
Cockerham, L. R., Yukl, S. A., Harvill, K., Somsouk, M., Joshi, S. K., Sinclair, E., Liegler, T., Hoh, R., Lyons, S., Hunt, P. W., Rupert, A., Sereti, I., Morcock, D. R., Rhodes, A., Emson, C., Hellerstein, M. K., Estes, J. D., Lewin, S., Deeks, S. G., & Hatano, H. (2017). A Randomized Controlled Trial of Lisinopril to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Individuals. Pathogens & immunity, 2(3), 310-334. https://doi.org/10.20411/pai.v2i3.207
Cockerham, Leslie R, et al. "A Randomized Controlled Trial of Lisinopril to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Individuals." Pathogens & immunity vol. 2,3 (2017): 310-334. doi: https://doi.org/10.20411/pai.v2i3.207
Cockerham LR, Yukl SA, Harvill K, Somsouk M, Joshi SK, Sinclair E, Liegler T, Hoh R, Lyons S, Hunt PW, Rupert A, Sereti I, Morcock DR, Rhodes A, Emson C, Hellerstein MK, Estes JD, Lewin S, Deeks SG, Hatano H. A Randomized Controlled Trial of Lisinopril to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Individuals. Pathog Immun. 2017;2(3):310-334. doi: 10.20411/pai.v2i3.207. Epub 2017 Aug 02. PMID: 28936485; PMCID: PMC5604865.
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Advances in use of mouse models to study the renin-angiotensin system.

Molecular and cellular endocrinology

Emathinger JM, Nelson JW, Gurley SB.
PMID: 33789143
Mol Cell Endocrinol. 2021 Jun 01;529:111255. doi: 10.1016/j.mce.2021.111255. Epub 2021 Mar 28.

The renin-angiotensin system (RAS) is a highly complex hormonal cascade that spans multiple organs and cell types to regulate solute and fluid balance along with cardiovascular function. Much of our current understanding of the functions of the RAS has...

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Emathinger JM, Nelson JW, Gurley SB. Advances in use of mouse models to study the renin-angiotensin system. Mol Cell Endocrinol. 2021;529:111255doi: 10.1016/j.mce.2021.111255.
Emathinger, J. M., Nelson, J. W., & Gurley, S. B. (2021). Advances in use of mouse models to study the renin-angiotensin system. Molecular and cellular endocrinology, 529111255. https://doi.org/10.1016/j.mce.2021.111255
Emathinger, Jacqueline M, et al. "Advances in use of mouse models to study the renin-angiotensin system." Molecular and cellular endocrinology vol. 529 (2021): 111255. doi: https://doi.org/10.1016/j.mce.2021.111255
Emathinger JM, Nelson JW, Gurley SB. Advances in use of mouse models to study the renin-angiotensin system. Mol Cell Endocrinol. 2021 Jun 01;529:111255. doi: 10.1016/j.mce.2021.111255. Epub 2021 Mar 28. PMID: 33789143.
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