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Showing 1 to 12 of 32 entries
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An Interprofessional Skills Workshop to Teach Family Caregivers of People Living with Dementia to Provide Complex Care.

Journal of interprofessional education & practice

Prado P, Norman RS, Vasquez L, Glassner A, Osuoha P, Meyer K, Brackett JR, White CL.
PMID: 34977361
J Interprof Educ Pract. 2022 Mar;26. doi: 10.1016/j.xjep.2021.100481. Epub 2021 Nov 18.

The purpose of this study was to evaluate the acceptability of and satisfaction with an interprofessional educational workshop to teach family caregivers of persons living with dementia to provide complex care. The workshop was developed by a team that...

CD122-directed interleukin-2 treatment mechanisms in bladder cancer differ from αPD-L1 and include tissue-selective γδ T cell activation.

Journal for immunotherapy of cancer

Reyes RM, Deng Y, Zhang D, Ji N, Mukherjee N, Wheeler K, Gupta HB, Padron AS, Kancharla A, Zhang C, Garcia M, Kornepati AVR, Boyman O, Conejo-Garcia JR, Svatek RS, Curiel TJ.
PMID: 33849925
J Immunother Cancer. 2021 Apr;9(4). doi: 10.1136/jitc-2020-002051.

BACKGROUND: Anti-programmed death-ligand 1 (αPD-L1) immunotherapy is approved to treat bladder cancer (BC) but is effective in

γδ T Cells Support Antigen-Specific αβ T cell-Mediated Antitumor Responses during BCG Treatment for Bladder Cancer.

Cancer immunology research

Ji N, Mukherjee N, Shu ZJ, Reyes RM, Meeks JJ, McConkey DJ, Gelfond JA, Curiel TJ, Svatek RS.
PMID: 34607803
Cancer Immunol Res. 2021 Dec;9(12):1491-1503. doi: 10.1158/2326-6066.CIR-21-0285. Epub 2021 Oct 04.

Bacillus Calmette-Guérin (BCG) is the most effective intravesical agent at reducing recurrence for patients with high-grade, non-muscle-invasive bladder cancer. Nevertheless, response to BCG is variable and strategies to boost BCG efficacy have not materialized. Prior work demonstrated a requirement...

Effectiveness of Exergaming in Improving Cognitive and Physical Function in People With Mild Cognitive Impairment or Dementia: Systematic Review.

JMIR serious games

Zhao Y, Feng H, Wu X, Du Y, Yang X, Hu M, Ning H, Liao L, Chen H, Zhao Y.
PMID: 32602841
JMIR Serious Games. 2020 Jun 30;8(2):e16841. doi: 10.2196/16841.

BACKGROUND: Individuals with mild cognitive impairment and dementia have impaired physical and cognitive functions, leading to a reduced quality of life compared with those without such impairment. Exergaming, which is defined as a combination of exercise and gaming, is...

Acetazolamide Treatment Prevents Redistribution of Astrocyte Aquaporin 4 after Murine Traumatic Brain Injury.

Neuroscience journal

Glober NK, Sprague S, Ahmad S, Mayfield KG, Fletcher LM, Digicaylioglu MH, Sayre NL.
PMID: 31187032
Neurosci J. 2019 May 02;2019:2831501. doi: 10.1155/2019/2831501. eCollection 2019.

After traumatic brain injury (TBI), multiple ongoing processes contribute to worsening and spreading of the primary injury to create a secondary injury. One major process involves disrupted fluid regulation to create vascular and cytotoxic edema in the affected area....

SARS-CoV-2 spike-specific memory B cells express markers of durable immunity after non-severe COVID-19 but not after severe disease.

bioRxiv : the preprint server for biology

Reyes RA, Clarke K, Gonzales SJ, Cantwell AM, Garza R, Catano G, Tragus RE, Patterson TF, Bol S, Bunnik EM.
PMID: 34611662
bioRxiv. 2021 Sep 27; doi: 10.1101/2021.09.24.461732.

SARS-CoV-2 infection elicits a robust B cell response, resulting in the generation of long-lived plasma cells and memory B cells. Here, we aimed to determine the effect of COVID-19 severity on the memory B cell response and characterize changes...

SARS-CoV-2 spike-specific memory B cells express higher levels of T-bet and FcRL5 after non-severe COVID-19 as compared to severe disease.

PloS one

Reyes RA, Clarke K, Gonzales SJ, Cantwell AM, Garza R, Catano G, Tragus RE, Patterson TF, Bol S, Bunnik EM.
PMID: 34936684
PLoS One. 2021 Dec 22;16(12):e0261656. doi: 10.1371/journal.pone.0261656. eCollection 2021.

SARS-CoV-2 infection elicits a robust B cell response, resulting in the generation of long-lived plasma cells and memory B cells. Here, we aimed to determine the effect of COVID-19 severity on the memory B cell response and characterize changes...

Simulation learning to train healthcare students in person-centered dementia care.

Gerontology & geriatrics education

Meyer K, James D, Amezaga B, White C.
PMID: 33081626
Gerontol Geriatr Educ. 2020 Oct 20;1-16. doi: 10.1080/02701960.2020.1838503. Epub 2020 Oct 20.

In coming decades, healthcare providers will treat a greater number of individuals living with Alzheimer's Disease and related dementias than ever. Simulation-based learning provides experiential learning opportunities to enhance clinical training, but little is known about how dementia simulation...

SARS-CoV-2 spike-specific memory B cells express markers of durable immunity after non-severe COVID-19 but not after severe disease.

bioRxiv : the preprint server for biology

Reyes RA, Clarke K, Gonzales SJ, Cantwell AM, Garza R, Catano G, Tragus RE, Patterson TF, Bol S, Bunnik EM.
PMID: 34611662
bioRxiv. 2021 Sep 27; doi: 10.1101/2021.09.24.461732.

SARS-CoV-2 infection elicits a robust B cell response, resulting in the generation of long-lived plasma cells and memory B cells. Here, we aimed to determine the effect of COVID-19 severity on the memory B cell response and characterize changes...

CD122-targeted interleukin-2 and αPD-L1 treat bladder cancer and melanoma via distinct mechanisms, including CD122-driven natural killer cell maturation.

Oncoimmunology

Reyes RM, Zhang C, Deng Y, Ji N, Mukherjee N, Padron AS, Clark CA, Svatek RS, Curiel TJ.
PMID: 34858732
Oncoimmunology. 2021 Nov 22;10(1):2006529. doi: 10.1080/2162402X.2021.2006529. eCollection 2021.

Bladder cancer (BC) and melanoma are amenable to immune checkpoint blockade (ICB) therapy, yet most patients with advanced/metastatic disease do not respond. CD122-targeted interleukin (IL)-2 can improve ICB efficacy, but mechanisms are unclear. We tested αPD-L1 and CD122-directed immunotherapy...

γδ T Cells Support Antigen-Specific αβ T cell-Mediated Antitumor Responses during BCG Treatment for Bladder Cancer.

Cancer immunology research

Ji N, Mukherjee N, Shu ZJ, Reyes RM, Meeks JJ, McConkey DJ, Gelfond JA, Curiel TJ, Svatek RS.
PMID: 34607803
Cancer Immunol Res. 2021 Dec;9(12):1491-1503. doi: 10.1158/2326-6066.CIR-21-0285. Epub 2021 Oct 04.

Bacillus Calmette-Guérin (BCG) is the most effective intravesical agent at reducing recurrence for patients with high-grade, non-muscle-invasive bladder cancer. Nevertheless, response to BCG is variable and strategies to boost BCG efficacy have not materialized. Prior work demonstrated a requirement...

The Differential Effects of Caregiving Intensity on Overnight Hospitalization.

Western journal of nursing research

Meyer K, Gassoumis Z, Wilber K.
PMID: 33764207
West J Nurs Res. 2021 Mar 25;1939459211002907. doi: 10.1177/01939459211002907. Epub 2021 Mar 25.

This study aims to examine how caregiving for a spouse affects caregivers' likelihood of overnight hospitalization. Using data from the Health and Retirement Study, we examine the odds of spousal caregivers experiencing an overnight hospitalization in the previous two...

Showing 1 to 12 of 32 entries