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Showing 1 to 12 of 127 entries
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Epilepsy during pregnancy: focus on management strategies.

International journal of women's health

Borgelt LM, Hart FM, Bainbridge JL.
PMID: 27703396
Int J Womens Health. 2016 Sep 19;8:505-517. doi: 10.2147/IJWH.S98973. eCollection 2016.

In the US, more than one million women with epilepsy are of childbearing age and have over 20,000 babies each year. Patients with epilepsy who become pregnant are at risk of complications, including changes in seizure frequency, maternal morbidity...

Microcephaly.

Children (Basel, Switzerland)

Hanzlik E, Gigante J.
PMID: 28598357
Children (Basel). 2017 Jun 09;4(6). doi: 10.3390/children4060047.

Microcephaly is defined as a head circumference more than two standard deviations below the mean for gender and age. Congenital microcephaly is present at birth, whereas postnatal microcephaly occurs later in life. Genetic abnormalities, syndromes, metabolic disorders, teratogens, infections,...

Training Genetic Counselors to provide teratogen counseling.

Journal of genetic counseling

Stein AK, Fine BA, Pergament E.
PMID: 24233862
J Genet Couns. 1994 Jun;3(2):133-40. doi: 10.1007/BF01423175.

Provision of teratogen counseling requires acquisition of knowledge and skills from several disciplines. Traditionally, training in teratogen counseling has occurred "on the job." We describe a formal, didactic and experiential curriculum for teratogen counseling as an integral part of...

The role of pharmacoepidemiology in pharmacovigilance: rational drug use in pregnancy.

Pharmacoepidemiology and drug safety

Czeizel AE.
PMID: 15073887
Pharmacoepidemiol Drug Saf. 1999 Apr;8:S55-61. doi: 10.1002/(SICI)1099-1557(199904)8:1+3.0.CO;2-1.

The most important objective of the Hungarian Case-Control Surveillance of Congenital Abnormalities is the postmarketing surveillance of the teratogenic effects of drugs. This dataset includes 22,865 pregnant women who had offspring with congenital abnormalities and 38,151 pregnant women who...

Teratogens acting through males.

Science (New York, N.Y.)

Kolata GB.
PMID: 17807239
Science. 1978 Nov 17;202(4369):733. doi: 10.1126/science.202.4369.733.

No abstract available.

Changes in visceral yolk sac ultrastructure after exposure of rat embryos to selected teratogens in vitro.

Toxicology in vitro : an international journal published in association with BIBRA

Daston GP, Burns JL, Chestnut MH.
PMID: 20702236
Toxicol In Vitro. 1990;4(4):593-7. doi: 10.1016/0887-2333(90)90122-a.

It has been determined that a number of teratogens alter the osmotic environment around the rat embryo, an effect that is associated with abnormal fluid accumulation (and ultimately abnormality) in the embryo. At least one of these teratogens, trypan...

The role of pharmacokinetics in determining the response of rodent embryos to teratogens in whole-embryo culture.

Toxicology in vitro : an international journal published in association with BIBRA

Sadler TW, Shum L, Warner CW, Smith MK.
PMID: 20702332
Toxicol In Vitro. 1988;2(3):175-80. doi: 10.1016/0887-2333(88)90005-7.

The rodent embryo's response to teratogenic insult in whole-embryo culture during the period of neurulation was characterized by determining the role of pharmacokinetics and embryonic recovery in producing abnormal growth and development. Five known teratogens, hydroxyurea, cyclophosphamide, cadmium, diphenylhydantoin,...

Epidemiology of prenatal genetic and environmental factors of mental retardation in cuba.

MEDICC review

Lantigua A, Portuondo M, Collazo T, Lardoeyt R.
PMID: 21483354
MEDICC Rev. 2008 Jan;10(1):29-36. doi: 10.37757/MR2008.V10.N1.9.

INTRODUCTION: One of the most sensitive disabilities in human beings is intellectual disability. In April, 2003, a 10-month study was completed of all persons in Cuba with mental retardation (MR), producing results that included epidemiological variables on a national...

Congenital diaphragmatic hernia following usage of lithium carbonate; is lithium a teratogen?.

Iranian journal of pediatrics

Hosseini SH, Mousavi SA, Rashidi H.
PMID: 23056695
Iran J Pediatr. 2010 Mar;20(1):127-30.

BACKGROUND: Lithium is used mainly for the treatment of Bipolar Disorder (BD). Case reports and several retrospective studies have demonstrated possible teratogenicity, but the data in different studies is inconclusive. The risk for cardiovascular malformations, particularly Ebstein's anomaly and...

Duplicated pituitary gland and odontoid process. A case report.

The neuroradiology journal

Usta Y, Sakha F, White WL, Little AS, Knecht L.
PMID: 24028990
Neuroradiol J. 2012 Jul;25(3):360-3. doi: 10.1177/197140091202500312. Epub 2012 Jun 26.

The development of the pituitary gland is not well understood, but duplication of the gland, a rare embryonic anomaly, may shed some light on the process. Since 1880 only about 40 cases have been described. A 56-year-old woman complained...

Asymmetrically enlarged parietal foramina in a rare case of Goldenhar syndrome with a possible etiopathogenesis.

Oncotarget

Al-Kzayer LFY, Sarsam SN, Alhur NY, Liu T, Nakazawa Y.
PMID: 29416828
Oncotarget. 2017 Dec 20;9(2):2962-2968. doi: 10.18632/oncotarget.23479. eCollection 2018 Jan 05.

Goldenhar´s syndrome (GS) also known as oculo-auriculo-vertebral spectrum (OAVS) is a relatively rare condition. GS is of multifactorial etiology that includes environmental and/or genetic factors, in addition to teratogens that disturb the blastogenesis. A 5-year-old girl from Saudi Arabia,...

Prenatal Neuropathologies in Autism Spectrum Disorder and Intellectual Disability: The Gestation of a Comprehensive Zebrafish Model.

Journal of developmental biology

Kozol RA.
PMID: 30513623
J Dev Biol. 2018 Nov 30;6(4). doi: 10.3390/jdb6040029.

Autism spectrum disorder (ASD) and intellectual disability (ID) are neurodevelopmental disorders with overlapping diagnostic behaviors and risk factors. These include embryonic exposure to teratogens and mutations in genes that have important functions prenatally. Animal models, including rodents and zebrafish,...

Showing 1 to 12 of 127 entries