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Showing 1 to 6 of 6 entries
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hsa-miR-29c-3p regulates biological function of colorectal cancer by targeting SPARC.

Oncotarget

Zhang S, Jin J, Tian X, Wu L.
PMID: 29262657
Oncotarget. 2017 Nov 10;8(61):104508-104524. doi: 10.18632/oncotarget.22356. eCollection 2017 Nov 28.

Colorectal cancer (CRC) is the most common type of behavioral cancers, miRNAs play a critical role in cancer development and progression. In the present study, we downloaded the original data from Gene Expression Omnibus (GEO) and conduct data analysis....

The hepatic compensatory response to elevated systemic sulfide promotes diabetes.

Cell reports

Carter RN, Gibbins MTG, Barrios-Llerena ME, Wilkie SE, Freddolino PL, Libiad M, Vitvitsky V, Emerson B, Le Bihan T, Brice M, Su H, Denham SG, Homer NZM, Mc Fadden C, Tailleux A, Faresse N, Sulpice T, Briand F, Gillingwater T, Ahn KH, Singha S, McMaster C, Hartley RC, Staels B, Gray GA, Finch AJ, Selman C, Banerjee R, Morton NM.
PMID: 34758301
Cell Rep. 2021 Nov 09;37(6):109958. doi: 10.1016/j.celrep.2021.109958.

Impaired hepatic glucose and lipid metabolism are hallmarks of type 2 diabetes. Increased sulfide production or sulfide donor compounds may beneficially regulate hepatic metabolism. Disposal of sulfide through the sulfide oxidation pathway (SOP) is critical for maintaining sulfide within...

Protective effect of Phellinus linteus polysaccharide extracts against thioacetamide-induced liver fibrosis in rats: a proteomics analysis.

Chinese medicine

Wang H, Wu G, Park HJ, Jiang PP, Sit WH, van Griensven LJ, Wan JM.
PMID: 23075396
Chin Med. 2012 Oct 18;7(1):23. doi: 10.1186/1749-8546-7-23.

BACKGROUND: The hepatoprotective potential of Phellinus linteus polysaccharide (PLP) extracts has been described. However, the molecular mechanism of PLP for the inhibition of liver fibrosis is unclear. This study aims to investigate the molecular protein signatures involved in the...

Corrigendum: Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness.

Nature medicine

Morton NM, Beltram J, Carter RN, Michailidou Z, Gorjanc G, McFadden C, Barrios-Llerena ME, Rodriguez-Cuenca S, Gibbins MTG, Aird RE, Moreno-Navarrete JM, Munger SC, Svenson KL, Gastaldello A, Ramage L, Naredo G, Zeyda M, Wang ZV, Howie AF, Saari A, Sipilä P, Stulnig TM, Gudnason V, Kenyon CJ, Seckl JR, Walker BR, Webster SP, Dunbar DR, Churchill GA, Vidal-Puig A, Fernandez-Real JM, Emilsson V, Horvat S.
PMID: 29634685
Nat Med. 2018 Apr 10;24(4):525. doi: 10.1038/nm0418-525e.

This corrects the article DOI: 10.1038/nm.4115.

Novel Characterization of Antioxidant Enzyme, 3-Mercaptopyruvate Sulfurtransferase-Knockout Mice: Overexpression of the Evolutionarily-Related Enzyme Rhodanese.

Antioxidants (Basel, Switzerland)

Nagahara N, Tanaka M, Tanaka Y, Ito T.
PMID: 31052467
Antioxidants (Basel). 2019 May 01;8(5). doi: 10.3390/antiox8050116.

The antioxidant enzyme, 3-mercaptopyruvate sulfurtransferase (MST, EC 2.8.1.2) is localized in the cytosol and mitochondria, while the evolutionarily-related enzyme, rhodanese (thiosulfate sulfurtransferase, TST, EC 2.8.1.1) is localized in the mitochondria. Recently, both enzymes have been shown to produce hydrogen...

Studies of functionally important structural flexibility of thiosulfate sulfurtransferase.

Biophysical journal

Horowitz P.
PMID: 19431407
Biophys J. 1980 Oct;32(1):641-3. doi: 10.1016/S0006-3495(80)85005-3.

No abstract available.

Showing 1 to 6 of 6 entries