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Showing 1 to 12 of 81 entries
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Association of Transforming Growth Factor Alpha Polymorphisms with Nonsyndromic Cleft Lip and Palate in Iranian Population.

Avicenna journal of medical biotechnology

Ebadifar A, Hamedi R, Khorram Khorshid HR, Saliminejad K, Kamali K, Aghakhani Moghadam F, Esmaeili Anvar N, Ameli N.
PMID: 26605011
Avicenna J Med Biotechnol. 2015 Oct-Dec;7(4):168-72.

BACKGROUND: Cleft lip with or without cleft palate (CL/P) is one of the most common congenital anomalies and the etiology of orofacial clefts is multifactorial. Transforming growth factor alpha (TGFA) is expressed at the medial edge epithelium of fusing...

Parental cigarette smoking, transforming growth factor-alpha gene variant and the risk of orofacial cleft in Iranian infants.

Iranian journal of basic medical sciences

Ebadifar A, Hamedi R, KhorramKhorshid HR, Kamali K, Moghadam FA.
PMID: 27279979
Iran J Basic Med Sci. 2016 Apr;19(4):366-73.

OBJECTIVES: We investigated the influence of genetic variation of the transforming growth-factor alpha (TGFA) locus on the relationship between smoking and oral clefts.MATERIALS AND METHODS: In this study 105 Iranian infants with non-syndromic cleft lip/palate and 218 controls with...

Effect of various growth-promoting factors on preimplantation bovine embryo development in vitro.

Theriogenology

Flood MR, Gage TL, Bunch TD.
PMID: 16727256
Theriogenology. 1993 Apr;39(4):823-33. doi: 10.1016/0093-691x(93)90421-z.

One-cell bovine embryos produced by in vitro oocyte maturation (IVM) and in vitro fertilization (IVF) were cultured in chemically defined medium (CDM) to which the following growth-promoting factors were added separately: transferrin (Tf, 10 ug/ml), epidermal growth factor (EGF),...

Correlation of transforming growth factor-alpha and epidermal growth factor receptor with proliferating cell nuclear antigen in human burn wounds.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society

Wenczak B, Nanney LB.
PMID: 17166098
Wound Repair Regen. 1993 Oct;1(4):219-30. doi: 10.1046/j.1524-475X.1993.10407.x.

The purpose of this study was to localize transforming growth factor-alpha, a mitogenic peptide, and its receptor, epidermal growth factor receptor, to correlate these findings with epithelial cell proliferation in human burn wounds. Proliferating cell nuclear antigen, a marker...

Effects of cytokines in burn blister fluids on fibroblast proliferation and their inhibition with the use of neutralizing antibodies.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society

Inoue M, Zhou LJ, Gunji H, Ono I, Kaneko F.
PMID: 17309693
Wound Repair Regen. 1996 Oct;4(4):426-32. doi: 10.1046/j.1524-475X.1996.40406.x.

Recent studies have shown that tissue exudates, such as burn blister fluid and donor site wound fluid, have promotive effects on wound healing. In the present study, results obtained with enzyme-linked immunosorbent assays showed that at least three cytokines,...

Clinical impact of serum transforming growth factor-alpha mRNA as a predictive biomarker for the prognosis of fulminant hepatitis.

Hepatology international

Miura N, Kabashima H, Shimizu M, Sato R, Tsukamoto T, Harada T, Takahashi S, Endo R, Nakayama N, Takikawa Y, Mochida S, Suzuki K, Hasegawa J, Shiota G.
PMID: 19669307
Hepatol Int. 2008 Jun;2(2):213-21. doi: 10.1007/s12072-008-9053-6. Epub 2008 Apr 09.

PURPOSE: We previously reported that measuring serum telomerase reverse transcriptase (hTERT) mRNA with a quantitative, one-step, real-time RT-PCR was superior to conventional tumor markers for hepatocellular carcinoma and lung cancer. Here, we examined serum regeneration-related mRNA detection as a...

Heparin-binding EGF-like growth factor expression and biological action in human pancreatic cancer cells.

International journal of oncology

Yokoyama M, Funatomi H, Hope C, Damm D, Friess H, Buchler M, Abraham J, Korc M.
PMID: 21544358
Int J Oncol. 1996 Feb;8(2):289-95. doi: 10.3892/ijo.8.2.289.

The epidermal growth factor (EGF) receptor is activated by EGF and other EGF-like growth factors, including heparin-binding epidermal growth factor-like growth factor (HB-EGF). We characterized the biological actions of HB-EGF in PANC-1 and COLO-357 human pancreatic cancer cell lines,...

Comparative study of TGF-alpha and P53 markers' expression in odontogenic keratocyst and orthokeratinaized odontogenic cyst.

Dental research journal

Deyhimi P, Hashemzade Z.
PMID: 23814560
Dent Res J (Isfahan). 2012 Dec;9:S39-44.

BACKGROUND: Odontogenic keratocyst (OKC) is an aggressive cyst and its recurrence is higher than other odontogenic cysts, orthokeratinized odontogenic cyst (OOC) is a cyst with moderate biological behavior in comparison with OKC, but with the probability of carcinomatous changes....

Immunohistochemical detection of cripto-1, amphiregulin and transforming growth-factor-alpha in human gastric carcinomas and intestinal metaplasias.

International journal of oncology

Saeki T, Salomon D, Normanno N, Johnson G, Gullick W, Mandai K, Moriwaki S, Takashima S, Kuniyasu M, Tahara E, Kawami H, Nishiyama M, Toge T.
PMID: 21559578
Int J Oncol. 1994 Aug;5(2):215-23. doi: 10.3892/ijo.5.2.215.

The expression and localization of cripto-1 (CR-1), amphiregulin (AR) and transforming growth factor alpha (TGFalpha) were assessed by immunocytochemistry in 37 primary human gastric tumors, 30 noninvolved gastric mucosa samples that were adjacent to carcinoma but exhibited intestinal metaplasia...

Asian sand dust enhances allergen-induced th2 allergic inflammatory changes and mucin production in BALB/c mouse lungs.

Allergy, asthma & immunology research

Kang IG, Jung JH, Kim ST.
PMID: 22754714
Allergy Asthma Immunol Res. 2012 Jul;4(4):206-13. doi: 10.4168/aair.2012.4.4.206. Epub 2012 Mar 09.

PURPOSE: Recent studies have reported that Asian sand dust (ASD) has a potential risk of aggravating airway inflammation. The purpose of this study was to investigate the effect of ASD on inflammation and mucin production in the airways of...

Autocrine transforming growth factor-alpha is associated with modulation of a 130 kD RB protein species and 116/110 Rb as revealed by an antisense TGF alpha expression vector.

International journal of oncology

Dobre C, Ziober B, Humphrey L, Brattain M.
PMID: 21544460
Int J Oncol. 1996 Jun;8(6):1025-33. doi: 10.3892/ijo.8.6.1025.

Specific RE protein species modulated by autocrine TGF alpha are unknown. HCT116 cells transfected with TGF alpha antisense expression vector were compared with control HCT116 NEO for mitogenesis and modulation of high MW (130, 120 kD) and low MW...

Organotypic and epidermal-dermal co-cultures of normal human keratinocytes and dermal cells: Regulation of transforming growth factor alpha, beta1 and beta2 mRNA levels.

Toxicology in vitro : an international journal published in association with BIBRA

Smola H, Thiekötter G, Baur M, Stark HJ, Breitkreutz D, Fusenig NE.
PMID: 20692978
Toxicol In Vitro. 1994 Aug;8(4):641-50. doi: 10.1016/0887-2333(94)90034-5.

Epidermal-dermal cell-cell interactions are recognized to influence keratinocyte proliferation in vivo as well as in vitro. To study the underlying molecular mechanisms of epithelial-mesenchymal interactions epidermal-dermal cell co-cultures and organotypic cultures were used. Steady-state mRNA levels are described for...

Showing 1 to 12 of 81 entries