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Showing 1 to 9 of 9 entries
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The PHACS SMARTT Study: Assessment of the Safety of In Utero Exposure to Antiretroviral Drugs.

Frontiers in immunology

Van Dyke RB, Chadwick EG, Hazra R, Williams PL, Seage GR.
PMID: 27242802
Front Immunol. 2016 May 23;7:199. doi: 10.3389/fimmu.2016.00199. eCollection 2016.

The Surveillance Monitoring for ART Toxicities (SMARTT) cohort of the Pediatric HIV/AIDS Cohort Study includes over 3,500 HIV-exposed but uninfected infants and children at 22 sites in the US, including Puerto Rico. The goal of the study is to...

Upfront dexrazoxane for the reduction of anthracycline-induced cardiotoxicity in adults with preexisting cardiomyopathy and cancer: a consecutive case series.

Cardio-oncology (London, England)

Ganatra S, Nohria A, Shah S, Groarke JD, Sharma A, Venesy D, Patten R, Gunturu K, Zarwan C, Neilan TG, Barac A, Hayek SS, Dani S, Solanki S, Mahmood SS, Lipshultz SE.
PMID: 32154008
Cardiooncology. 2019 Jan 29;5:1. doi: 10.1186/s40959-019-0036-7. eCollection 2019.

BACKGROUND: Cardiotoxicity associated with anthracycline-based chemotherapies has limited their use in patients with preexisting cardiomyopathy or heart failure. Dexrazoxane protects against the cardiotoxic effects of anthracyclines, but in the USA and some European countries, its use had been restricted...

Genomics Links Inflammation With Neurocognitive Impairment in Children Living With Human Immunodeficiency Virus Type-1.

The Journal of infectious diseases

Rawat P, Brummel SS, Singh KK, Kim J, Frazer KA, Nichols S, Seage GR, Williams PL, Van Dyke RB, Harismendy O, Trout RN, Spector SA.
PMID: 33373444
J Infect Dis. 2021 Sep 01;224(5):870-880. doi: 10.1093/infdis/jiaa792.

BACKGROUND: We identified host single-nucleotide variants (SNVs) associated with neurocognitive impairment (NCI) in perinatally HIV-infected (PHIV) children.METHODS: Whole-exome sequencing (WES) was performed on 217 PHIV with cognitive score for age (CSA) 

Genomics Links Inflammation With Neurocognitive Impairment in Children Living With Human Immunodeficiency Virus Type-1.

The Journal of infectious diseases

Rawat P, Brummel SS, Singh KK, Kim J, Frazer KA, Nichols S, Seage GR, Williams PL, Van Dyke RB, Harismendy O, Trout RN, Spector SA.
PMID: 33373444
J Infect Dis. 2021 Sep 01;224(5):870-880. doi: 10.1093/infdis/jiaa792.

BACKGROUND: We identified host single-nucleotide variants (SNVs) associated with neurocognitive impairment (NCI) in perinatally HIV-infected (PHIV) children.METHODS: Whole-exome sequencing (WES) was performed on 217 PHIV with cognitive score for age (CSA) 

When is early septal myectomy in children with hypertrophic cardiomyopathy justified?.

Translational pediatrics

Bansal N, Barach P, Amdani SM, Lipshultz SE.
PMID: 30460188
Transl Pediatr. 2018 Oct;7(4):362-366. doi: 10.21037/tp.2018.09.08.

No abstract available.

Newborn Hearing Screenings in Human Immunodeficiency Virus-Exposed Uninfected Infants.

Journal of AIDS and immune research

Torre P, Zeldow B, Yao TJ, Hoffman HJ, Siberry GK, Purswani MU, Frederick T, Spector SA, Williams PL.
PMID: 28459118
J AIDS Immune Res. 2016;1(1). Epub 2016 Sep 05.

Perinatal HIV infection and congenital cytomegalovirus (CMV) infection may increase the risk for hearing loss. We examined 1,435 infants enrolled in the Surveillance Monitoring of ART Toxicities (SMARTT) study of the Pediatric HIV/AIDS Cohort Study (PHACS) network, a prospective...

Blood lead levels and neurodevelopmental function in perinatally HIV-exposed, uninfected children in a US-based longitudinal cohort study.

AIDS research and human retroviruses

Tassiopoulos K, Huo Y, Braun J, Williams PL, Smith R, Aschengrau A, Nichols S, Hazra R, Meyer WA, Knapp K, Deygoo NS, Seage Iii GR.
PMID: 28322573
AIDS Res Hum Retroviruses. 2017 Sep;33(9):919-928. doi: 10.1089/AID.2016.0265. Epub 2017 Mar 21.

BACKGROUND: While children's exposure to environmental lead in the U.S. has decreased, areas of elevated levels remain. Because lead exposure is a risk factor for developmental delays, it should be considered when studying neurodevelopmental effects of in-utero antiretroviral medication...

Genetically determined ancestry is more informative than self-reported race in HIV-infected and -exposed children.

Medicine

Spector SA, Brummel SS, Nievergelt CM, Maihofer AX, Singh KK, Purswani MU, Williams PL, Hazra R, Van Dyke R, Seage GR.
PMID: 27603370
Medicine (Baltimore). 2016 Sep;95(36):e4733. doi: 10.1097/MD.0000000000004733.

The Pediatric HIV/AIDS Cohort Study (PHACS), the largest ongoing longitudinal study of perinatal HIV-infected (PHIV) and HIV-exposed, uninfected (PHEU) children in the United States, comprises the Surveillance Monitoring of Antiretroviral Therapy [ART] Toxicities (SMARTT) Study in PHEU children and...

Growth patterns of uninfected children born to women living with perinatally- versus non-perinatally-acquired HIV.

AIDS (London, England)

Yu W, Jacobson DL, Williams PL, Patel K, Geffner ME, van Dyke RB, Kacanek D, DiMeglio LA, Jao J.
PMID: 34860195
AIDS. 2021 Dec 06; doi: 10.1097/QAD.0000000000003136. Epub 2021 Dec 06.

OBJECTIVE: To compare long-term growth between HIV-exposed uninfected children (CHEU) born to women with perinatally-acquired HIV (CHEU-PHIV) and CHEU born to women with non-perinatally-acquired HIV (CHEU-NPHIV).DESIGN: Longitudinal analysis of anthropometric measurements from a U.S.-based multisite prospective cohort study enrolling...

Showing 1 to 9 of 9 entries