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Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study.

Diabetologia

Downie CG, Dimos SF, Bien SA, Hu Y, Darst BF, Polfus LM, Wang Y, Wojcik GL, Tao R, Raffield LM, Armstrong ND, Polikowsky HG, Below JE, Correa A, Irvin MR, Rasmussen-Torvik LJF, Carlson CS, Phillips LS, Liu S, Pankow JS, Rich SS, Rotter JI, Buyske S, Matise TC, North KE, Avery CL, Haiman CA, Loos RJF, Kooperberg C, Graff M, Highland HM.
PMID: 34951656
Diabetologia. 2021 Dec 24; doi: 10.1007/s00125-021-05635-9. Epub 2021 Dec 24.

AIMS/HYPOTHESIS: Type 2 diabetes is a growing global public health challenge. Investigating quantitative traits, including fasting glucose, fasting insulin and HbAMETHODS: We conducted a GWAS of fasting glucose (n = 52,267), fasting insulin (n = 48,395) and HbARESULTS: Four...

Cite
Downie CG, Dimos SF, Bien SA, et al. Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study. Diabetologia. 2021;doi: 10.1007/s00125-021-05635-9.
Downie, C. G., Dimos, S. F., Bien, S. A., Hu, Y., Darst, B. F., Polfus, L. M., Wang, Y., Wojcik, G. L., Tao, R., Raffield, L. M., Armstrong, N. D., Polikowsky, H. G., Below, J. E., Correa, A., Irvin, M. R., Rasmussen-Torvik, L. J. F., Carlson, C. S., Phillips, L. S., Liu, S., Pankow, J. S., Rich, S. S., Rotter, J. I., Buyske, S., Matise, T. C., North, K. E., Avery, C. L., Haiman, C. A., Loos, R. J. F., Kooperberg, C., Graff, M., & Highland, H. M. (2021). Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study. Diabetologia, . https://doi.org/10.1007/s00125-021-05635-9
Downie, Carolina G, et al. "Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study." Diabetologia vol. (2021). doi: https://doi.org/10.1007/s00125-021-05635-9
Downie CG, Dimos SF, Bien SA, Hu Y, Darst BF, Polfus LM, Wang Y, Wojcik GL, Tao R, Raffield LM, Armstrong ND, Polikowsky HG, Below JE, Correa A, Irvin MR, Rasmussen-Torvik LJF, Carlson CS, Phillips LS, Liu S, Pankow JS, Rich SS, Rotter JI, Buyske S, Matise TC, North KE, Avery CL, Haiman CA, Loos RJF, Kooperberg C, Graff M, Highland HM. Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study. Diabetologia. 2021 Dec 24; doi: 10.1007/s00125-021-05635-9. Epub 2021 Dec 24. PMID: 34951656.
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Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study.

Diabetologia

Downie CG, Dimos SF, Bien SA, Hu Y, Darst BF, Polfus LM, Wang Y, Wojcik GL, Tao R, Raffield LM, Armstrong ND, Polikowsky HG, Below JE, Correa A, Irvin MR, Rasmussen-Torvik LJF, Carlson CS, Phillips LS, Liu S, Pankow JS, Rich SS, Rotter JI, Buyske S, Matise TC, North KE, Avery CL, Haiman CA, Loos RJF, Kooperberg C, Graff M, Highland HM.
PMID: 34951656
Diabetologia. 2021 Dec 24; doi: 10.1007/s00125-021-05635-9. Epub 2021 Dec 24.

AIMS/HYPOTHESIS: Type 2 diabetes is a growing global public health challenge. Investigating quantitative traits, including fasting glucose, fasting insulin and HbAMETHODS: We conducted a GWAS of fasting glucose (n = 52,267), fasting insulin (n = 48,395) and HbARESULTS: Four...

Cite
Downie CG, Dimos SF, Bien SA, et al. Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study. Diabetologia. 2021;doi: 10.1007/s00125-021-05635-9.
Downie, C. G., Dimos, S. F., Bien, S. A., Hu, Y., Darst, B. F., Polfus, L. M., Wang, Y., Wojcik, G. L., Tao, R., Raffield, L. M., Armstrong, N. D., Polikowsky, H. G., Below, J. E., Correa, A., Irvin, M. R., Rasmussen-Torvik, L. J. F., Carlson, C. S., Phillips, L. S., Liu, S., Pankow, J. S., Rich, S. S., Rotter, J. I., Buyske, S., Matise, T. C., North, K. E., Avery, C. L., Haiman, C. A., Loos, R. J. F., Kooperberg, C., Graff, M., & Highland, H. M. (2021). Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study. Diabetologia, . https://doi.org/10.1007/s00125-021-05635-9
Downie, Carolina G, et al. "Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study." Diabetologia vol. (2021). doi: https://doi.org/10.1007/s00125-021-05635-9
Downie CG, Dimos SF, Bien SA, Hu Y, Darst BF, Polfus LM, Wang Y, Wojcik GL, Tao R, Raffield LM, Armstrong ND, Polikowsky HG, Below JE, Correa A, Irvin MR, Rasmussen-Torvik LJF, Carlson CS, Phillips LS, Liu S, Pankow JS, Rich SS, Rotter JI, Buyske S, Matise TC, North KE, Avery CL, Haiman CA, Loos RJF, Kooperberg C, Graff M, Highland HM. Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study. Diabetologia. 2021 Dec 24; doi: 10.1007/s00125-021-05635-9. Epub 2021 Dec 24. PMID: 34951656.
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Generalization of adiposity genetic loci to US Hispanic women.

Nutrition & diabetes

Graff M, Fernández-Rhodes L, Liu S, Carlson C, Wassertheil-Smoller S, Neuhouser M, Reiner A, Kooperberg C, Rampersaud E, Manson JE, Kuller LH, Howard BV, Ochs-Balcom HM, Johnson KC, Vitolins MZ, Sucheston L, Monda K, North KE.
PMID: 23978819
Nutr Diabetes. 2013 Aug 26;3:e85. doi: 10.1038/nutd.2013.26.

BACKGROUND: Obesity is a public health concern. Yet the identification of adiposity-related genetic variants among United States (US) Hispanics, which is the largest US minority group, remains largely unknown.OBJECTIVE: To interrogate an a priori list of 47 (32 overall...

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Graff M, Fernández-Rhodes L, Liu S, et al. Generalization of adiposity genetic loci to US Hispanic women. Nutr Diabetes. 2013;3:e85doi: 10.1038/nutd.2013.26.
Graff, M., Fernández-Rhodes, L., Liu, S., Carlson, C., Wassertheil-Smoller, S., Neuhouser, M., Reiner, A., Kooperberg, C., Rampersaud, E., Manson, J. E., Kuller, L. H., Howard, B. V., Ochs-Balcom, H. M., Johnson, K. C., Vitolins, M. Z., Sucheston, L., Monda, K., & North, K. E. (2013). Generalization of adiposity genetic loci to US Hispanic women. Nutrition & diabetes, 3e85. https://doi.org/10.1038/nutd.2013.26
Graff, M, et al. "Generalization of adiposity genetic loci to US Hispanic women." Nutrition & diabetes vol. 3 (2013): e85. doi: https://doi.org/10.1038/nutd.2013.26
Graff M, Fernández-Rhodes L, Liu S, Carlson C, Wassertheil-Smoller S, Neuhouser M, Reiner A, Kooperberg C, Rampersaud E, Manson JE, Kuller LH, Howard BV, Ochs-Balcom HM, Johnson KC, Vitolins MZ, Sucheston L, Monda K, North KE. Generalization of adiposity genetic loci to US Hispanic women. Nutr Diabetes. 2013 Aug 26;3:e85. doi: 10.1038/nutd.2013.26. PMID: 23978819; PMCID: PMC3759132.
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Generalization and fine mapping of red blood cell trait genetic associations to multi-ethnic populations: The PAGE Study.

American journal of hematology

Jo Hodonsky C, Schurmann C, Schick UM, Kocarnik J, Tao R, van Rooij FJ, Wassel C, Buyske S, Fornage M, Hindorff LA, Floyd JS, Ganesh SK, Lin DY, North KE, Reiner AP, Loos RJ, Kooperberg C, Avery CL.
PMID: 29905378
Am J Hematol. 2018 Jun 15; doi: 10.1002/ajh.25161. Epub 2018 Jun 15.

Red blood cell (RBC) traits provide insight into a wide range of physiological states and exhibit moderate to high heritability, making them excellent candidates for genetic studies to inform underlying biologic mechanisms. Previous RBC trait genome-wide association studies were...

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Jo Hodonsky C, Schurmann C, Schick UM, et al. Generalization and fine mapping of red blood cell trait genetic associations to multi-ethnic populations: The PAGE Study. Am J Hematol. 2018;doi: 10.1002/ajh.25161.
Jo Hodonsky, C., Schurmann, C., Schick, U. M., Kocarnik, J., Tao, R., van Rooij, F. J., Wassel, C., Buyske, S., Fornage, M., Hindorff, L. A., Floyd, J. S., Ganesh, S. K., Lin, D. Y., North, K. E., Reiner, A. P., Loos, R. J., Kooperberg, C., & Avery, C. L. (2018). Generalization and fine mapping of red blood cell trait genetic associations to multi-ethnic populations: The PAGE Study. American journal of hematology, . https://doi.org/10.1002/ajh.25161
Jo Hodonsky, Chani, et al. "Generalization and fine mapping of red blood cell trait genetic associations to multi-ethnic populations: The PAGE Study." American journal of hematology vol. (2018). doi: https://doi.org/10.1002/ajh.25161
Jo Hodonsky C, Schurmann C, Schick UM, Kocarnik J, Tao R, van Rooij FJ, Wassel C, Buyske S, Fornage M, Hindorff LA, Floyd JS, Ganesh SK, Lin DY, North KE, Reiner AP, Loos RJ, Kooperberg C, Avery CL. Generalization and fine mapping of red blood cell trait genetic associations to multi-ethnic populations: The PAGE Study. Am J Hematol. 2018 Jun 15; doi: 10.1002/ajh.25161. Epub 2018 Jun 15. PMID: 29905378; PMCID: PMC6300146.
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Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study.

Frontiers in genetics

Lin BM, Nadkarni GN, Tao R, Graff M, Fornage M, Buyske S, Matise TC, Highland HM, Wilkens LR, Carlson CS, Park SL, Setiawan VW, Ambite JL, Heiss G, Boerwinkle E, Lin DY, Morris AP, Loos RJF, Kooperberg C, North KE, Wassel CL, Franceschini N.
PMID: 31178898
Front Genet. 2019 May 24;10:494. doi: 10.3389/fgene.2019.00494. eCollection 2019.

BACKGROUND: Chronic kidney disease (CKD) is common and disproportionally burdens United States ethnic minorities. Its genetic determinants may differ by disease severity and clinical stages. To uncover genetic factors associated CKD severity among high-risk ethnic groups, we performed genome-wide...

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Lin BM, Nadkarni GN, Tao R, et al. Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study. Front Genet. 2019;10:494doi: 10.3389/fgene.2019.00494.
Lin, B. M., Nadkarni, G. N., Tao, R., Graff, M., Fornage, M., Buyske, S., Matise, T. C., Highland, H. M., Wilkens, L. R., Carlson, C. S., Park, S. L., Setiawan, V. W., Ambite, J. L., Heiss, G., Boerwinkle, E., Lin, D. Y., Morris, A. P., Loos, R. J. F., Kooperberg, C., North, K. E., Wassel, C. L., & Franceschini, N. (2019). Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study. Frontiers in genetics, 10494. https://doi.org/10.3389/fgene.2019.00494
Lin, Bridget M, et al. "Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study." Frontiers in genetics vol. 10 (2019): 494. doi: https://doi.org/10.3389/fgene.2019.00494
Lin BM, Nadkarni GN, Tao R, Graff M, Fornage M, Buyske S, Matise TC, Highland HM, Wilkens LR, Carlson CS, Park SL, Setiawan VW, Ambite JL, Heiss G, Boerwinkle E, Lin DY, Morris AP, Loos RJF, Kooperberg C, North KE, Wassel CL, Franceschini N. Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study. Front Genet. 2019 May 24;10:494. doi: 10.3389/fgene.2019.00494. eCollection 2019. PMID: 31178898; PMCID: PMC6544117.
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Showing 1 to 5 of 5 entries