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Allele-specific variation at APOE increases nonalcoholic fatty liver disease and obesity but decreases risk of Alzheimer's disease and myocardial infarction.

Human molecular genetics

Palmer ND, Kahali B, Kuppa A, Chen Y, Du X, Feitosa MF, Bielak LF, O'Connell JR, Musani SK, Guo X, Smith AV, Ryan KA, Eirksdottir G, Allison MA, Bowden DW, Budoff MJ, Carr JJ, Chen YI, Taylor KD, Correa A, Crudup BF, Halligan B, Yang J, Kardia SLR, Launer LJ, Fu YP, Mosley TH, Norris JM, Terry JG, O'Donnell CJ, Rotter JI, Wagenknecht LE, Gudnason V, Province MA, Peyser PA, Speliotes EK.
PMID: 33856023
Hum Mol Genet. 2021 Jul 09;30(15):1443-1456. doi: 10.1093/hmg/ddab096.

Nonalcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease and is highly correlated with metabolic disease. NAFLD results from environmental exposures acting on a susceptible polygenic background. This study performed the largest multiethnic investigation of...

Cite
Palmer ND, Kahali B, Kuppa A, et al. Allele-specific variation at APOE increases nonalcoholic fatty liver disease and obesity but decreases risk of Alzheimer's disease and myocardial infarction. Hum Mol Genet. 2021;30(15):1443-1456doi: 10.1093/hmg/ddab096.
Palmer, N. D., Kahali, B., Kuppa, A., Chen, Y., Du, X., Feitosa, M. F., Bielak, L. F., O'Connell, J. R., Musani, S. K., Guo, X., Smith, A. V., Ryan, K. A., Eirksdottir, G., Allison, M. A., Bowden, D. W., Budoff, M. J., Carr, J. J., Chen, Y. I., Taylor, K. D., Correa, A., Crudup, B. F., Halligan, B., Yang, J., Kardia, S. L. R., Launer, L. J., Fu, Y. P., Mosley, T. H., Norris, J. M., Terry, J. G., O'Donnell, C. J., Rotter, J. I., Wagenknecht, L. E., Gudnason, V., Province, M. A., Peyser, P. A., & Speliotes, E. K. (2021). Allele-specific variation at APOE increases nonalcoholic fatty liver disease and obesity but decreases risk of Alzheimer's disease and myocardial infarction. Human molecular genetics, 30(15), 1443-1456. https://doi.org/10.1093/hmg/ddab096
Palmer, Nicholette D, et al. "Allele-specific variation at APOE increases nonalcoholic fatty liver disease and obesity but decreases risk of Alzheimer's disease and myocardial infarction." Human molecular genetics vol. 30,15 (2021): 1443-1456. doi: https://doi.org/10.1093/hmg/ddab096
Palmer ND, Kahali B, Kuppa A, Chen Y, Du X, Feitosa MF, Bielak LF, O'Connell JR, Musani SK, Guo X, Smith AV, Ryan KA, Eirksdottir G, Allison MA, Bowden DW, Budoff MJ, Carr JJ, Chen YI, Taylor KD, Correa A, Crudup BF, Halligan B, Yang J, Kardia SLR, Launer LJ, Fu YP, Mosley TH, Norris JM, Terry JG, O'Donnell CJ, Rotter JI, Wagenknecht LE, Gudnason V, Province MA, Peyser PA, Speliotes EK. Allele-specific variation at APOE increases nonalcoholic fatty liver disease and obesity but decreases risk of Alzheimer's disease and myocardial infarction. Hum Mol Genet. 2021 Jul 09;30(15):1443-1456. doi: 10.1093/hmg/ddab096. PMID: 33856023; PMCID: PMC8283205.
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Genetic and functional evidence links a missense variant in .

Science (New York, N.Y.)

Montasser ME, Van Hout CV, Miloscio L, Howard AD, Rosenberg A, Callaway M, Shen B, Li N, Locke AE, Verweij N, De T, Ferreira MA, Lotta LA, Baras A, Daly TJ, Hartford SA, Lin W, Mao Y, Ye B, White D, Gong G, Perry JA, Ryan KA, Fang Q, Tzoneva G, Pefanis E, Hunt C, Tang Y, Lee L, Sztalryd-Woodle C, Mitchell BD, Healy M, Streeten EA, Taylor SI, O'Connell JR, Economides AN, Della Gatta G, Shuldiner AR.
PMID: 34855475
Science. 2021 Dec 03;374(6572):1221-1227. doi: 10.1126/science.abe0348. Epub 2021 Dec 02.

[Figure: see text].

Cite
Montasser ME, Van Hout CV, Miloscio L, et al. Genetic and functional evidence links a missense variant in . Science. 2021;374(6572):1221-1227doi: 10.1126/science.abe0348.
Montasser, M. E., Van Hout, C. V., Miloscio, L., Howard, A. D., Rosenberg, A., Callaway, M., Shen, B., Li, N., Locke, A. E., Verweij, N., De, T., Ferreira, M. A., Lotta, L. A., Baras, A., Daly, T. J., Hartford, S. A., Lin, W., Mao, Y., Ye, B., White, D., Gong, G., Perry, J. A., Ryan, K. A., Fang, Q., Tzoneva, G., Pefanis, E., Hunt, C., Tang, Y., Lee, L., Sztalryd-Woodle, C., Mitchell, B. D., Healy, M., Streeten, E. A., Taylor, S. I., O'Connell, J. R., Economides, A. N., Della Gatta, G., & Shuldiner, A. R. (2021). Genetic and functional evidence links a missense variant in . Science (New York, N.Y.), 374(6572), 1221-1227. https://doi.org/10.1126/science.abe0348
Montasser, May E, et al. "Genetic and functional evidence links a missense variant in ." Science (New York, N.Y.) vol. 374,6572 (2021): 1221-1227. doi: https://doi.org/10.1126/science.abe0348
Montasser ME, Van Hout CV, Miloscio L, Howard AD, Rosenberg A, Callaway M, Shen B, Li N, Locke AE, Verweij N, De T, Ferreira MA, Lotta LA, Baras A, Daly TJ, Hartford SA, Lin W, Mao Y, Ye B, White D, Gong G, Perry JA, Ryan KA, Fang Q, Tzoneva G, Pefanis E, Hunt C, Tang Y, Lee L, Sztalryd-Woodle C, Mitchell BD, Healy M, Streeten EA, Taylor SI, O'Connell JR, Economides AN, Della Gatta G, Shuldiner AR. Genetic and functional evidence links a missense variant in . Science. 2021 Dec 03;374(6572):1221-1227. doi: 10.1126/science.abe0348. Epub 2021 Dec 02. PMID: 34855475.
Copy Download .nbib Format: NLM
Showing 1 to 2 of 2 entries