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White matter changes in psychosis risk relate to development and are not impacted by the transition to psychosis.

Molecular psychiatry

Di Biase MA, Cetin-Karayumak S, Lyall AE, Zalesky A, Cho KIK, Zhang F, Kubicki M, Rathi Y, Lyons MG, Bouix S, Billah T, Anticevic A, Schleifer C, Adkinson BD, Ji JL, Tamayo Z, Addington J, Bearden CE, Cornblatt BA, Keshavan MS, Mathalon DH, McGlashan TH, Perkins DO, Cadenhead KS, Tsuang MT, Woods SW, Stone WS, Shenton ME, Cannon TD, Pasternak O.
PMID: 34024906
Mol Psychiatry. 2021 Nov;26(11):6833-6844. doi: 10.1038/s41380-021-01128-8. Epub 2021 May 24.

Subtle alterations in white matter microstructure are observed in youth at clinical high risk (CHR) for psychosis. However, the timing of these changes and their relationships to the emergence of psychosis remain unclear. Here, we track the evolution of...

White matter changes in psychosis risk relate to development and are not impacted by the transition to psychosis.

Molecular psychiatry

Di Biase MA, Cetin-Karayumak S, Lyall AE, Zalesky A, Cho KIK, Zhang F, Kubicki M, Rathi Y, Lyons MG, Bouix S, Billah T, Anticevic A, Schleifer C, Adkinson BD, Ji JL, Tamayo Z, Addington J, Bearden CE, Cornblatt BA, Keshavan MS, Mathalon DH, McGlashan TH, Perkins DO, Cadenhead KS, Tsuang MT, Woods SW, Stone WS, Shenton ME, Cannon TD, Pasternak O.
PMID: 34024906
Mol Psychiatry. 2021 Nov;26(11):6833-6844. doi: 10.1038/s41380-021-01128-8. Epub 2021 May 24.

Subtle alterations in white matter microstructure are observed in youth at clinical high risk (CHR) for psychosis. However, the timing of these changes and their relationships to the emergence of psychosis remain unclear. Here, we track the evolution of...

North American Prodrome Longitudinal Study (NAPLS 3): Methods and baseline description.

Schizophrenia research

Addington J, Liu L, Brummitt K, Bearden CE, Cadenhead KS, Cornblatt BA, Keshavan M, Mathalon DH, McGlashan TH, Perkins DO, Seidman LJ, Stone W, Tsuang MT, Walker EF, Woods SW, Cannon TD.
PMID: 32317224
Schizophr Res. 2020 Apr 18; doi: 10.1016/j.schres.2020.04.010. Epub 2020 Apr 18.

The North American Prodrome Longitudinal Study (NAPLS) is a consortium of nine programs focusing on youth at clinical high risk (CHR) for psychosis. Funded by the National Institute of Mental Health (NIMH), the sites are located at Emory University,...

Prodromal Symptom Severity Predicts Accelerated Gray Matter Reduction and Third Ventricle Expansion Among Clinically High Risk Youth Developing Psychotic Disorders.

Molecular neuropsychiatry

Chung Y, Jacobson A, He G, van Erp TG, McEwen S, Addington J, Bearden CE, Cadenhead K, Cornblatt B, Mathalon DH, McGlashan T, Perkins D, Seidman LJ, Tsuang M, Walker E, Woods SW, Heinssen R, Cannon TD.
PMID: 26005673
Mol Neuropsychiatry. 2015 May 01;1(1):13-22. doi: 10.1159/000371887.

A recent prospective longitudinal neuroimaging study of 274 prodromal risk syndrome subjects revealed that those who later developed full-blown psychotic symptoms exhibited accelerated gray matter loss and third ventricle expansion around the time of onset of psychosis. Previous studies...

Theory of Mind, Emotion Recognition and Social Perception in Individuals at Clinical High Risk for Psychosis: findings from the NAPLS-2 cohort.

Schizophrenia research. Cognition

Barbato M, Liu L, Cadenhead KS, Cannon TD, Cornblatt BA, McGlashan TH, Perkins DO, Seidman LJ, Tsuang MT, Walker EF, Woods SW, Bearden CE, Mathalon DH, Heinssen R, Addington J.
PMID: 27695675
Schizophr Res Cogn. 2015 Sep;2(3):133-139. doi: 10.1016/j.scog.2015.04.004. Epub 2015 May 16.

Social cognition, the mental operations that underlie social interactions, is a major construct to investigate in schizophrenia. Impairments in social cognition are present before the onset of psychosis, and even in unaffected first-degree relatives, suggesting that social cognition may...

White matter changes in psychosis risk relate to development and are not impacted by the transition to psychosis.

Molecular psychiatry

Di Biase MA, Cetin-Karayumak S, Lyall AE, Zalesky A, Cho KIK, Zhang F, Kubicki M, Rathi Y, Lyons MG, Bouix S, Billah T, Anticevic A, Schleifer C, Adkinson BD, Ji JL, Tamayo Z, Addington J, Bearden CE, Cornblatt BA, Keshavan MS, Mathalon DH, McGlashan TH, Perkins DO, Cadenhead KS, Tsuang MT, Woods SW, Stone WS, Shenton ME, Cannon TD, Pasternak O.
PMID: 34024906
Mol Psychiatry. 2021 Nov;26(11):6833-6844. doi: 10.1038/s41380-021-01128-8. Epub 2021 May 24.

Subtle alterations in white matter microstructure are observed in youth at clinical high risk (CHR) for psychosis. However, the timing of these changes and their relationships to the emergence of psychosis remain unclear. Here, we track the evolution of...

Life Event Stress and Reduced Cortical Thickness in Youth at Clinical High Risk for Psychosis and Healthy Control Subjects.

Biological psychiatry. Cognitive neuroscience and neuroimaging

Aberizk K, Collins MA, Addington J, Bearden CE, Cadenhead KS, Cornblatt BA, Mathalon DH, McGlashan TH, Perkins DO, Tsuang MT, Woods SW, Cannon TD, Walker EF.
PMID: 33930604
Biol Psychiatry Cogn Neurosci Neuroimaging. 2021 Apr 28; doi: 10.1016/j.bpsc.2021.04.011. Epub 2021 Apr 28.

BACKGROUND: A decline in cortical thickness during early life appears to be a normal neuromaturational process. Accelerated cortical thinning has been linked with conversion to psychosis among individuals at clinical high risk for psychosis (CHR-P). Previous research indicates that...

White matter changes in psychosis risk relate to development and are not impacted by the transition to psychosis.

Molecular psychiatry

Di Biase MA, Cetin-Karayumak S, Lyall AE, Zalesky A, Cho KIK, Zhang F, Kubicki M, Rathi Y, Lyons MG, Bouix S, Billah T, Anticevic A, Schleifer C, Adkinson BD, Ji JL, Tamayo Z, Addington J, Bearden CE, Cornblatt BA, Keshavan MS, Mathalon DH, McGlashan TH, Perkins DO, Cadenhead KS, Tsuang MT, Woods SW, Stone WS, Shenton ME, Cannon TD, Pasternak O.
PMID: 34024906
Mol Psychiatry. 2021 Nov;26(11):6833-6844. doi: 10.1038/s41380-021-01128-8. Epub 2021 May 24.

Subtle alterations in white matter microstructure are observed in youth at clinical high risk (CHR) for psychosis. However, the timing of these changes and their relationships to the emergence of psychosis remain unclear. Here, we track the evolution of...

Childhood trauma and cognitive functioning in individuals at clinical high risk (CHR) for psychosis.

Development and psychopathology

Velikonja T, Velthorst E, Zinberg J, Cannon TD, Cornblatt BA, Perkins DO, Cadenhead KS, Tsuang MT, Addington J, Woods SW, McGlashan T, Mathalon DH, Stone W, Keshavan M, Seidman L, Bearden CE.
PMID: 31959269
Dev Psychopathol. 2021 Feb;33(1):53-64. doi: 10.1017/S095457941900155X.

Evidence suggests that early trauma may have a negative effect on cognitive functioning in individuals with psychosis, yet the relationship between childhood trauma and cognition among those at clinical high risk (CHR) for psychosis remains unexplored. Our sample consisted...

White matter changes in psychosis risk relate to development and are not impacted by the transition to psychosis.

Molecular psychiatry

Di Biase MA, Cetin-Karayumak S, Lyall AE, Zalesky A, Cho KIK, Zhang F, Kubicki M, Rathi Y, Lyons MG, Bouix S, Billah T, Anticevic A, Schleifer C, Adkinson BD, Ji JL, Tamayo Z, Addington J, Bearden CE, Cornblatt BA, Keshavan MS, Mathalon DH, McGlashan TH, Perkins DO, Cadenhead KS, Tsuang MT, Woods SW, Stone WS, Shenton ME, Cannon TD, Pasternak O.
PMID: 34024906
Mol Psychiatry. 2021 May 24; doi: 10.1038/s41380-021-01128-8. Epub 2021 May 24.

Subtle alterations in white matter microstructure are observed in youth at clinical high risk (CHR) for psychosis. However, the timing of these changes and their relationships to the emergence of psychosis remain unclear. Here, we track the evolution of...

Showing 1 to 10 of 10 entries