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Exploratory Genome-Wide Interaction Analysis of Nonsteroidal Anti-inflammatory Drugs and Predicted Gene Expression on Colorectal Cancer Risk.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Wang X, Su YR, Petersen PS, Bien S, Schmit SL, Drew DA, Albanes D, Berndt SI, Brenner H, Campbell PT, Casey G, Chang-Claude J, Gallinger SJ, Gruber SB, Haile RW, Harrison TA, Hoffmeister M, Jacobs EJ, Jenkins MA, Joshi AD, Li L, Lin Y, Lindor NM, Marchand LL, Martin V, Milne R, Maclnnis R, Moreno V, Nan H, Newcomb PA, Potter JD, Rennert G, Rennert H, Slattery ML, Thibodeau SN, Weinstein SJ, Woods MO, Chan AT, White E, Hsu L, Peters U.
PMID: 32651213
Cancer Epidemiol Biomarkers Prev. 2020 Sep;29(9):1800-1808. doi: 10.1158/1055-9965.EPI-19-1018. Epub 2020 Jul 10.

BACKGROUND: Regular use of nonsteroidal anti-inflammatory drugs (NSAID) is associated with lower risk of colorectal cancer. Genome-wide interaction analysis on single variants (G × E) has identified several SNPs that may interact with NSAIDs to confer colorectal cancer risk,...

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Wang X, Su YR, Petersen PS, et al. Exploratory Genome-Wide Interaction Analysis of Nonsteroidal Anti-inflammatory Drugs and Predicted Gene Expression on Colorectal Cancer Risk. Cancer Epidemiol Biomarkers Prev. 2020;29(9):1800-1808doi: 10.1158/1055-9965.EPI-19-1018.
Wang, X., Su, Y. R., Petersen, P. S., Bien, S., Schmit, S. L., Drew, D. A., Albanes, D., Berndt, S. I., Brenner, H., Campbell, P. T., Casey, G., Chang-Claude, J., Gallinger, S. J., Gruber, S. B., Haile, R. W., Harrison, T. A., Hoffmeister, M., Jacobs, E. J., Jenkins, M. A., Joshi, A. D., Li, L., Lin, Y., Lindor, N. M., Marchand, L. L., Martin, V., Milne, R., Maclnnis, R., Moreno, V., Nan, H., Newcomb, P. A., Potter, J. D., Rennert, G., Rennert, H., Slattery, M. L., Thibodeau, S. N., Weinstein, S. J., Woods, M. O., Chan, A. T., White, E., Hsu, L., & Peters, U. (2020). Exploratory Genome-Wide Interaction Analysis of Nonsteroidal Anti-inflammatory Drugs and Predicted Gene Expression on Colorectal Cancer Risk. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 29(9), 1800-1808. https://doi.org/10.1158/1055-9965.EPI-19-1018
Wang, Xiaoliang, et al. "Exploratory Genome-Wide Interaction Analysis of Nonsteroidal Anti-inflammatory Drugs and Predicted Gene Expression on Colorectal Cancer Risk." Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology vol. 29,9 (2020): 1800-1808. doi: https://doi.org/10.1158/1055-9965.EPI-19-1018
Wang X, Su YR, Petersen PS, Bien S, Schmit SL, Drew DA, Albanes D, Berndt SI, Brenner H, Campbell PT, Casey G, Chang-Claude J, Gallinger SJ, Gruber SB, Haile RW, Harrison TA, Hoffmeister M, Jacobs EJ, Jenkins MA, Joshi AD, Li L, Lin Y, Lindor NM, Marchand LL, Martin V, Milne R, Maclnnis R, Moreno V, Nan H, Newcomb PA, Potter JD, Rennert G, Rennert H, Slattery ML, Thibodeau SN, Weinstein SJ, Woods MO, Chan AT, White E, Hsu L, Peters U. Exploratory Genome-Wide Interaction Analysis of Nonsteroidal Anti-inflammatory Drugs and Predicted Gene Expression on Colorectal Cancer Risk. Cancer Epidemiol Biomarkers Prev. 2020 Sep;29(9):1800-1808. doi: 10.1158/1055-9965.EPI-19-1018. Epub 2020 Jul 10. PMID: 32651213; PMCID: PMC7556991.
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Measurement Error in Spatial Exposure Models: Study Design Implications.

Environmetrics

Thomas DC.
PMID: 24729740
Environmetrics. 2013 Dec 01;24(8):518-520. doi: 10.1002/env.2243.

No abstract available.

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Thomas DC. Measurement Error in Spatial Exposure Models: Study Design Implications. Environmetrics. 2013;24(8):518-520doi: 10.1002/env.2243.
Thomas, D. C. (2013). Measurement Error in Spatial Exposure Models: Study Design Implications. Environmetrics, 24(8), 518-520. https://doi.org/10.1002/env.2243
Thomas, Duncan C. "Measurement Error in Spatial Exposure Models: Study Design Implications." Environmetrics vol. 24,8 (2013): 518-520. doi: https://doi.org/10.1002/env.2243
Thomas DC. Measurement Error in Spatial Exposure Models: Study Design Implications. Environmetrics. 2013 Dec 01;24(8):518-520. doi: 10.1002/env.2243. PMID: 24729740; PMCID: PMC3979582.
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Corrigendum: genome-wide association study of colorectal cancer identifies six new susceptibility loci.

Nature communications

Schumacher FR, Schmit SL, Jiao S, Edlund CK, Wang H, Zhang B, Hsu L, Huang SC, Fischer CP, Harju JF, Idos GE, Lejbkowicz F, Manion FJ, McDonnell K, McNeil CE, Melas M, Rennert HS, Shi W, Thomas DC, Van Den Berg DJ, Hutter CM, Aragaki AK, Butterbach K, Caan BJ, Carlson CS, Chanock SJ, Curtis KR, Fuchs CS, Gala M, Giovannucci EL, Gogarten SM, Hayes RB, Henderson B, Hunter DJ, Jackson RD, Kolonel LN, Kooperberg C, Küry S, LaCroix A, Laurie CC, Laurie CA, Lemire M, Levine D, Ma J, Makar KW, Qu C, Taverna D, Ulrich CM, Wu K, Kono S, West DW, Berndt SI, Bezieau S, Brenner H, Campbell PT, Chan AT, Chang-Claude J, Coetzee GA, Conti DV, Duggan D, Figueiredo JC, Fortini BK, Gallinger SJ, Gauderman WJ, Giles G, Green R, Haile R, Harrison TA, Hoffmeister M, Hopper JL, Hudson TJ, Jacobs E, Iwasaki M, Jee SH, Jenkins M, Jia WH, Joshi A, Li L, Lindor NM, Matsuo K, Moreno V, Mukherjee B, Newcomb PA, Potter JD, Raskin L, Rennert G, Rosse S, Severi G, Schoen RE, Seminara D, Shu XO, Slattery ML, Tsugane S, White E, Xiang YB, Zanke BW, Zheng W, Le Marchand L, Casey G, Gruber SB, Peters U.
PMID: 26498495
Nat Commun. 2015 Oct 26;6:8739. doi: 10.1038/ncomms9739.

No abstract available.

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Schumacher FR, Schmit SL, Jiao S, et al. Corrigendum: genome-wide association study of colorectal cancer identifies six new susceptibility loci. Nat Commun. 2015;6:8739doi: 10.1038/ncomms9739.
Schumacher, F. R., Schmit, S. L., Jiao, S., Edlund, C. K., Wang, H., Zhang, B., Hsu, L., Huang, S. C., Fischer, C. P., Harju, J. F., Idos, G. E., Lejbkowicz, F., Manion, F. J., McDonnell, K., McNeil, C. E., Melas, M., Rennert, H. S., Shi, W., Thomas, D. C., Van Den Berg, D. J., Hutter, C. M., Aragaki, A. K., Butterbach, K., Caan, B. J., Carlson, C. S., Chanock, S. J., Curtis, K. R., Fuchs, C. S., Gala, M., Giovannucci, E. L., Gogarten, S. M., Hayes, R. B., Henderson, B., Hunter, D. J., Jackson, R. D., Kolonel, L. N., Kooperberg, C., Küry, S., LaCroix, A., Laurie, C. C., Laurie, C. A., Lemire, M., Levine, D., Ma, J., Makar, K. W., Qu, C., Taverna, D., Ulrich, C. M., Wu, K., Kono, S., West, D. W., Berndt, S. I., Bezieau, S., Brenner, H., Campbell, P. T., Chan, A. T., Chang-Claude, J., Coetzee, G. A., Conti, D. V., Duggan, D., Figueiredo, J. C., Fortini, B. K., Gallinger, S. J., Gauderman, W. J., Giles, G., Green, R., Haile, R., Harrison, T. A., Hoffmeister, M., Hopper, J. L., Hudson, T. J., Jacobs, E., Iwasaki, M., Jee, S. H., Jenkins, M., Jia, W. H., Joshi, A., Li, L., Lindor, N. M., Matsuo, K., Moreno, V., Mukherjee, B., Newcomb, P. A., Potter, J. D., Raskin, L., Rennert, G., Rosse, S., Severi, G., Schoen, R. E., Seminara, D., Shu, X. O., Slattery, M. L., Tsugane, S., White, E., Xiang, Y. B., Zanke, B. W., Zheng, W., Le Marchand, L., Casey, G., Gruber, S. B., & Peters, U. (2015). Corrigendum: genome-wide association study of colorectal cancer identifies six new susceptibility loci. Nature communications, 68739. https://doi.org/10.1038/ncomms9739
Schumacher, Fredrick R, et al. "Corrigendum: genome-wide association study of colorectal cancer identifies six new susceptibility loci." Nature communications vol. 6 (2015): 8739. doi: https://doi.org/10.1038/ncomms9739
Schumacher FR, Schmit SL, Jiao S, Edlund CK, Wang H, Zhang B, Hsu L, Huang SC, Fischer CP, Harju JF, Idos GE, Lejbkowicz F, Manion FJ, McDonnell K, McNeil CE, Melas M, Rennert HS, Shi W, Thomas DC, Van Den Berg DJ, Hutter CM, Aragaki AK, Butterbach K, Caan BJ, Carlson CS, Chanock SJ, Curtis KR, Fuchs CS, Gala M, Giovannucci EL, Gogarten SM, Hayes RB, Henderson B, Hunter DJ, Jackson RD, Kolonel LN, Kooperberg C, Küry S, LaCroix A, Laurie CC, Laurie CA, Lemire M, Levine D, Ma J, Makar KW, Qu C, Taverna D, Ulrich CM, Wu K, Kono S, West DW, Berndt SI, Bezieau S, Brenner H, Campbell PT, Chan AT, Chang-Claude J, Coetzee GA, Conti DV, Duggan D, Figueiredo JC, Fortini BK, Gallinger SJ, Gauderman WJ, Giles G, Green R, Haile R, Harrison TA, Hoffmeister M, Hopper JL, Hudson TJ, Jacobs E, Iwasaki M, Jee SH, Jenkins M, Jia WH, Joshi A, Li L, Lindor NM, Matsuo K, Moreno V, Mukherjee B, Newcomb PA, Potter JD, Raskin L, Rennert G, Rosse S, Severi G, Schoen RE, Seminara D, Shu XO, Slattery ML, Tsugane S, White E, Xiang YB, Zanke BW, Zheng W, Le Marchand L, Casey G, Gruber SB, Peters U. Corrigendum: genome-wide association study of colorectal cancer identifies six new susceptibility loci. Nat Commun. 2015 Oct 26;6:8739. doi: 10.1038/ncomms9739. PMID: 26498495.
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Association between ALDH2 and ADH1B Polymorphisms and the Risk for Colorectal Cancer in Koreans.

Cancer research and treatment

Choi CK, Shin MH, Cho SH, Kim HY, Zheng W, Long J, Kweon SS.
PMID: 33421985
Cancer Res Treat. 2021 Jul;53(3):754-762. doi: 10.4143/crt.2020.478. Epub 2020 Dec 24.

PURPOSE: Excessive alcohol consumption has been linked to an increased risk of colorectal cancer (CRC). We evaluated the association between alcohol-related genetic variants and CRC risk.MATERIALS AND METHODS: The study cohort consisted of 5,435 CRC cases and 3,553 population-based...

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Choi CK, Shin MH, Cho SH, et al. Association between ALDH2 and ADH1B Polymorphisms and the Risk for Colorectal Cancer in Koreans. Cancer Res Treat. 2020;53(3):754-762doi: 10.4143/crt.2020.478.
Choi, C. K., Shin, M. H., Cho, S. H., Kim, H. Y., Zheng, W., Long, J., & Kweon, S. S. (2021). Association between ALDH2 and ADH1B Polymorphisms and the Risk for Colorectal Cancer in Koreans. Cancer research and treatment, 53(3), 754-762. https://doi.org/10.4143/crt.2020.478
Choi, Chang Kyun, et al. "Association between ALDH2 and ADH1B Polymorphisms and the Risk for Colorectal Cancer in Koreans." Cancer research and treatment vol. 53,3 (2021): 754-762. doi: https://doi.org/10.4143/crt.2020.478
Choi CK, Shin MH, Cho SH, Kim HY, Zheng W, Long J, Kweon SS. Association between ALDH2 and ADH1B Polymorphisms and the Risk for Colorectal Cancer in Koreans. Cancer Res Treat. 2021 Jul;53(3):754-762. doi: 10.4143/crt.2020.478. Epub 2020 Dec 24. PMID: 33421985; PMCID: PMC8291179.
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Rare Variants in the DNA Repair Pathway and the Risk of Colorectal Cancer.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Matejcic M, Shaban HA, Quintana MW, Schumacher FR, Edlund CK, Naghi L, Pai RK, Haile RW, Levine AJ, Buchanan DD, Jenkins MA, Figueiredo JC, Rennert G, Gruber SB, Li L, Casey G, Conti DV, Schmit SL.
PMID: 33627384
Cancer Epidemiol Biomarkers Prev. 2021 May;30(5):895-903. doi: 10.1158/1055-9965.EPI-20-1457. Epub 2021 Feb 24.

BACKGROUND: Inherited susceptibility is an important contributor to colorectal cancer risk, and rare variants in key genes or pathways could account in part for the missing proportion of colorectal cancer heritability.METHODS: We conducted an exome-wide association study including 2,327...

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Matejcic M, Shaban HA, Quintana MW, et al. Rare Variants in the DNA Repair Pathway and the Risk of Colorectal Cancer. Cancer Epidemiol Biomarkers Prev. 2021;30(5):895-903doi: 10.1158/1055-9965.EPI-20-1457.
Matejcic, M., Shaban, H. A., Quintana, M. W., Schumacher, F. R., Edlund, C. K., Naghi, L., Pai, R. K., Haile, R. W., Levine, A. J., Buchanan, D. D., Jenkins, M. A., Figueiredo, J. C., Rennert, G., Gruber, S. B., Li, L., Casey, G., Conti, D. V., & Schmit, S. L. (2021). Rare Variants in the DNA Repair Pathway and the Risk of Colorectal Cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 30(5), 895-903. https://doi.org/10.1158/1055-9965.EPI-20-1457
Matejcic, Marco, et al. "Rare Variants in the DNA Repair Pathway and the Risk of Colorectal Cancer." Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology vol. 30,5 (2021): 895-903. doi: https://doi.org/10.1158/1055-9965.EPI-20-1457
Matejcic M, Shaban HA, Quintana MW, Schumacher FR, Edlund CK, Naghi L, Pai RK, Haile RW, Levine AJ, Buchanan DD, Jenkins MA, Figueiredo JC, Rennert G, Gruber SB, Li L, Casey G, Conti DV, Schmit SL. Rare Variants in the DNA Repair Pathway and the Risk of Colorectal Cancer. Cancer Epidemiol Biomarkers Prev. 2021 May;30(5):895-903. doi: 10.1158/1055-9965.EPI-20-1457. Epub 2021 Feb 24. PMID: 33627384; PMCID: PMC8102340.
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Circulating Levels of Testosterone, Sex Hormone Binding Globulin and Colorectal Cancer Risk: Observational and Mendelian Randomization Analyses.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Dimou N, Mori N, Harlid S, Harbs J, Martin RM, Smith-Byrne K, Papadimitriou N, Bishop DT, Casey G, Colorado-Yohar SM, Cotterchio M, Cross AJ, Marchand LL, Lin Y, Offit K, Onland-Moret NC, Peters U, Potter JD, Rohan TE, Weiderpass E, Gunter MJ, Murphy N.
PMID: 33879453
Cancer Epidemiol Biomarkers Prev. 2021 Jul;30(7):1336-1348. doi: 10.1158/1055-9965.EPI-20-1690. Epub 2021 Apr 20.

BACKGROUND: Epidemiologic studies evaluating associations between sex steroid hormones and colorectal cancer risk have yielded inconsistent results. To elucidate the role of circulating levels of testosterone, and sex hormone-binding globulin (SHBG) in colorectal cancer risk, we conducted observational and...

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Dimou N, Mori N, Harlid S, et al. Circulating Levels of Testosterone, Sex Hormone Binding Globulin and Colorectal Cancer Risk: Observational and Mendelian Randomization Analyses. Cancer Epidemiol Biomarkers Prev. 2021;30(7):1336-1348doi: 10.1158/1055-9965.EPI-20-1690.
Dimou, N., Mori, N., Harlid, S., Harbs, J., Martin, R. M., Smith-Byrne, K., Papadimitriou, N., Bishop, D. T., Casey, G., Colorado-Yohar, S. M., Cotterchio, M., Cross, A. J., Marchand, L. L., Lin, Y., Offit, K., Onland-Moret, N. C., Peters, U., Potter, J. D., Rohan, T. E., Weiderpass, E., Gunter, M. J., & Murphy, N. (2021). Circulating Levels of Testosterone, Sex Hormone Binding Globulin and Colorectal Cancer Risk: Observational and Mendelian Randomization Analyses. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 30(7), 1336-1348. https://doi.org/10.1158/1055-9965.EPI-20-1690
Dimou, Niki, et al. "Circulating Levels of Testosterone, Sex Hormone Binding Globulin and Colorectal Cancer Risk: Observational and Mendelian Randomization Analyses." Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology vol. 30,7 (2021): 1336-1348. doi: https://doi.org/10.1158/1055-9965.EPI-20-1690
Dimou N, Mori N, Harlid S, Harbs J, Martin RM, Smith-Byrne K, Papadimitriou N, Bishop DT, Casey G, Colorado-Yohar SM, Cotterchio M, Cross AJ, Marchand LL, Lin Y, Offit K, Onland-Moret NC, Peters U, Potter JD, Rohan TE, Weiderpass E, Gunter MJ, Murphy N. Circulating Levels of Testosterone, Sex Hormone Binding Globulin and Colorectal Cancer Risk: Observational and Mendelian Randomization Analyses. Cancer Epidemiol Biomarkers Prev. 2021 Jul;30(7):1336-1348. doi: 10.1158/1055-9965.EPI-20-1690. Epub 2021 Apr 20. PMID: 33879453.
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Two-phase and family-based designs for next-generation sequencing studies.

Frontiers in genetics

Thomas DC, Yang Z, Yang F.
PMID: 24379824
Front Genet. 2013 Dec 13;4:276. doi: 10.3389/fgene.2013.00276.

The cost of next-generation sequencing is now approaching that of early GWAS panels, but is still out of reach for large epidemiologic studies and the millions of rare variants expected poses challenges for distinguishing causal from non-causal variants. We...

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Thomas DC, Yang Z, Yang F. Two-phase and family-based designs for next-generation sequencing studies. Front Genet. 2013;4:276doi: 10.3389/fgene.2013.00276.
Thomas, D. C., Yang, Z., & Yang, F. (2013). Two-phase and family-based designs for next-generation sequencing studies. Frontiers in genetics, 4276. https://doi.org/10.3389/fgene.2013.00276
Thomas, Duncan C, et al. "Two-phase and family-based designs for next-generation sequencing studies." Frontiers in genetics vol. 4 (2013): 276. doi: https://doi.org/10.3389/fgene.2013.00276
Thomas DC, Yang Z, Yang F. Two-phase and family-based designs for next-generation sequencing studies. Front Genet. 2013 Dec 13;4:276. doi: 10.3389/fgene.2013.00276. PMID: 24379824; PMCID: PMC3861783.
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A Combined Proteomics and Mendelian Randomization Approach to Investigate the Effects of Aspirin-Targeted Proteins on Colorectal Cancer.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Nounu A, Greenhough A, Heesom KJ, Richmond RC, Zheng J, Weinstein SJ, Albanes D, Baron JA, Hopper JL, Figueiredo JC, Newcomb PA, Lindor NM, Casey G, Platz EA, Le Marchand L, Ulrich CM, Li CI, van Duijnhoven FJB, Gsur A, Campbell PT, Moreno V, Vodicka P, Vodickova L, Brenner H, Chang-Claude J, Hoffmeister M, Sakoda LC, Slattery ML, Schoen RE, Gunter MJ, Castellví-Bel S, Kim HR, Kweon SS, Chan AT, Li L, Zheng W, Bishop DT, Buchanan DD, Giles GG, Gruber SB, Rennert G, Stadler ZK, Harrison TA, Lin Y, Keku TO, Woods MO, Schafmayer C, Van Guelpen B, Gallinger S, Hampel H, Berndt SI, Pharoah PDP, Lindblom A, Wolk A, Wu AH, White E, Peters U, Drew DA, Scherer D, Bermejo JL, Williams AC, Relton CL.
PMID: 33318029
Cancer Epidemiol Biomarkers Prev. 2021 Mar;30(3):564-575. doi: 10.1158/1055-9965.EPI-20-1176. Epub 2020 Dec 14.

BACKGROUND: Evidence for aspirin's chemopreventative properties on colorectal cancer (CRC) is substantial, but its mechanism of action is not well-understood. We combined a proteomic approach with Mendelian randomization (MR) to identify possible new aspirin targets that decrease CRC risk.METHODS:...

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Nounu A, Greenhough A, Heesom KJ, et al. A Combined Proteomics and Mendelian Randomization Approach to Investigate the Effects of Aspirin-Targeted Proteins on Colorectal Cancer. Cancer Epidemiol Biomarkers Prev. 2020;30(3):564-575doi: 10.1158/1055-9965.EPI-20-1176.
Nounu, A., Greenhough, A., Heesom, K. J., Richmond, R. C., Zheng, J., Weinstein, S. J., Albanes, D., Baron, J. A., Hopper, J. L., Figueiredo, J. C., Newcomb, P. A., Lindor, N. M., Casey, G., Platz, E. A., Le Marchand, L., Ulrich, C. M., Li, C. I., van Duijnhoven, F. J. B., Gsur, A., Campbell, P. T., Moreno, V., Vodicka, P., Vodickova, L., Brenner, H., Chang-Claude, J., Hoffmeister, M., Sakoda, L. C., Slattery, M. L., Schoen, R. E., Gunter, M. J., Castellví-Bel, S., Kim, H. R., Kweon, S. S., Chan, A. T., Li, L., Zheng, W., Bishop, D. T., Buchanan, D. D., Giles, G. G., Gruber, S. B., Rennert, G., Stadler, Z. K., Harrison, T. A., Lin, Y., Keku, T. O., Woods, M. O., Schafmayer, C., Van Guelpen, B., Gallinger, S., Hampel, H., Berndt, S. I., Pharoah, P. D. P., Lindblom, A., Wolk, A., Wu, A. H., White, E., Peters, U., Drew, D. A., Scherer, D., Bermejo, J. L., Williams, A. C., & Relton, C. L. (2021). A Combined Proteomics and Mendelian Randomization Approach to Investigate the Effects of Aspirin-Targeted Proteins on Colorectal Cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 30(3), 564-575. https://doi.org/10.1158/1055-9965.EPI-20-1176
Nounu, Aayah, et al. "A Combined Proteomics and Mendelian Randomization Approach to Investigate the Effects of Aspirin-Targeted Proteins on Colorectal Cancer." Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology vol. 30,3 (2021): 564-575. doi: https://doi.org/10.1158/1055-9965.EPI-20-1176
Nounu A, Greenhough A, Heesom KJ, Richmond RC, Zheng J, Weinstein SJ, Albanes D, Baron JA, Hopper JL, Figueiredo JC, Newcomb PA, Lindor NM, Casey G, Platz EA, Le Marchand L, Ulrich CM, Li CI, van Duijnhoven FJB, Gsur A, Campbell PT, Moreno V, Vodicka P, Vodickova L, Brenner H, Chang-Claude J, Hoffmeister M, Sakoda LC, Slattery ML, Schoen RE, Gunter MJ, Castellví-Bel S, Kim HR, Kweon SS, Chan AT, Li L, Zheng W, Bishop DT, Buchanan DD, Giles GG, Gruber SB, Rennert G, Stadler ZK, Harrison TA, Lin Y, Keku TO, Woods MO, Schafmayer C, Van Guelpen B, Gallinger S, Hampel H, Berndt SI, Pharoah PDP, Lindblom A, Wolk A, Wu AH, White E, Peters U, Drew DA, Scherer D, Bermejo JL, Williams AC, Relton CL. A Combined Proteomics and Mendelian Randomization Approach to Investigate the Effects of Aspirin-Targeted Proteins on Colorectal Cancer. Cancer Epidemiol Biomarkers Prev. 2021 Mar;30(3):564-575. doi: 10.1158/1055-9965.EPI-20-1176. Epub 2020 Dec 14. PMID: 33318029; PMCID: PMC8086774.
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Genetically Predicted Circulating C-Reactive Protein Concentration and Colorectal Cancer Survival: A Mendelian Randomization Consortium Study.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Hua X, Dai JY, Lindström S, Harrison TA, Lin Y, Alberts SR, Alwers E, Berndt SI, Brenner H, Buchanan DD, Campbell PT, Casey G, Chang-Claude J, Gallinger S, Giles GG, Goldberg RM, Gunter MJ, Hoffmeister M, Jenkins MA, Joshi AD, Ma W, Milne RL, Murphy N, Pai RK, Sakoda LC, Schoen RE, Shi Q, Slattery ML, Song M, White E, Marchand LL, Chan AT, Peters U, Newcomb PA.
PMID: 33972368
Cancer Epidemiol Biomarkers Prev. 2021 Jul;30(7):1349-1358. doi: 10.1158/1055-9965.EPI-20-1848. Epub 2021 May 10.

BACKGROUND: A positive association between circulating C-reactive protein (CRP) and colorectal cancer survival was reported in observational studies, which are susceptible to unmeasured confounding and reverse causality. We used a Mendelian randomization approach to evaluate the association between genetically...

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Hua X, Dai JY, Lindström S, et al. Genetically Predicted Circulating C-Reactive Protein Concentration and Colorectal Cancer Survival: A Mendelian Randomization Consortium Study. Cancer Epidemiol Biomarkers Prev. 2021;30(7):1349-1358doi: 10.1158/1055-9965.EPI-20-1848.
Hua, X., Dai, J. Y., Lindström, S., Harrison, T. A., Lin, Y., Alberts, S. R., Alwers, E., Berndt, S. I., Brenner, H., Buchanan, D. D., Campbell, P. T., Casey, G., Chang-Claude, J., Gallinger, S., Giles, G. G., Goldberg, R. M., Gunter, M. J., Hoffmeister, M., Jenkins, M. A., Joshi, A. D., Ma, W., Milne, R. L., Murphy, N., Pai, R. K., Sakoda, L. C., Schoen, R. E., Shi, Q., Slattery, M. L., Song, M., White, E., Marchand, L. L., Chan, A. T., Peters, U., & Newcomb, P. A. (2021). Genetically Predicted Circulating C-Reactive Protein Concentration and Colorectal Cancer Survival: A Mendelian Randomization Consortium Study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 30(7), 1349-1358. https://doi.org/10.1158/1055-9965.EPI-20-1848
Hua, Xinwei, et al. "Genetically Predicted Circulating C-Reactive Protein Concentration and Colorectal Cancer Survival: A Mendelian Randomization Consortium Study." Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology vol. 30,7 (2021): 1349-1358. doi: https://doi.org/10.1158/1055-9965.EPI-20-1848
Hua X, Dai JY, Lindström S, Harrison TA, Lin Y, Alberts SR, Alwers E, Berndt SI, Brenner H, Buchanan DD, Campbell PT, Casey G, Chang-Claude J, Gallinger S, Giles GG, Goldberg RM, Gunter MJ, Hoffmeister M, Jenkins MA, Joshi AD, Ma W, Milne RL, Murphy N, Pai RK, Sakoda LC, Schoen RE, Shi Q, Slattery ML, Song M, White E, Marchand LL, Chan AT, Peters U, Newcomb PA. Genetically Predicted Circulating C-Reactive Protein Concentration and Colorectal Cancer Survival: A Mendelian Randomization Consortium Study. Cancer Epidemiol Biomarkers Prev. 2021 Jul;30(7):1349-1358. doi: 10.1158/1055-9965.EPI-20-1848. Epub 2021 May 10. PMID: 33972368; PMCID: PMC8254760.
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Tests for Gene-Environment Interactions and Joint Effects With Exposure Misclassification.

American journal of epidemiology

Boonstra PS, Mukherjee B, Gruber SB, Ahn J, Schmit SL, Chatterjee N.
PMID: 26755675
Am J Epidemiol. 2016 Feb 01;183(3):237-47. doi: 10.1093/aje/kwv198. Epub 2016 Jan 10.

The number of methods for genome-wide testing of gene-environment (G-E) interactions continues to increase, with the aim of discovering new genetic risk factors and obtaining insight into the disease-gene-environment relationship. The relative performance of these methods, assessed on the...

Cite
Boonstra PS, Mukherjee B, Gruber SB, et al. Tests for Gene-Environment Interactions and Joint Effects With Exposure Misclassification. Am J Epidemiol. 2016;183(3):237-47doi: 10.1093/aje/kwv198.
Boonstra, P. S., Mukherjee, B., Gruber, S. B., Ahn, J., Schmit, S. L., & Chatterjee, N. (2016). Tests for Gene-Environment Interactions and Joint Effects With Exposure Misclassification. American journal of epidemiology, 183(3), 237-47. https://doi.org/10.1093/aje/kwv198
Boonstra, Philip S, et al. "Tests for Gene-Environment Interactions and Joint Effects With Exposure Misclassification." American journal of epidemiology vol. 183,3 (2016): 237-47. doi: https://doi.org/10.1093/aje/kwv198
Boonstra PS, Mukherjee B, Gruber SB, Ahn J, Schmit SL, Chatterjee N. Tests for Gene-Environment Interactions and Joint Effects With Exposure Misclassification. Am J Epidemiol. 2016 Feb 01;183(3):237-47. doi: 10.1093/aje/kwv198. Epub 2016 Jan 10. PMID: 26755675; PMCID: PMC4724093.
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Some surprising twists on the road to discovering the contribution of rare variants to complex diseases.

Human heredity

Thomas DC.
PMID: 23594489
Hum Hered. 2012;74(3):113-7. doi: 10.1159/000347020. Epub 2013 Apr 11.

No abstract available.

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Thomas DC. Some surprising twists on the road to discovering the contribution of rare variants to complex diseases. Hum Hered. 2013;74(3):113-7doi: 10.1159/000347020.
Thomas, D. C. (2012). Some surprising twists on the road to discovering the contribution of rare variants to complex diseases. Human heredity, 74(3), 113-7. https://doi.org/10.1159/000347020
Thomas, Duncan C. "Some surprising twists on the road to discovering the contribution of rare variants to complex diseases." Human heredity vol. 74,3 (2012): 113-7. doi: https://doi.org/10.1159/000347020
Thomas DC. Some surprising twists on the road to discovering the contribution of rare variants to complex diseases. Hum Hered. 2012;74(3):113-7. doi: 10.1159/000347020. Epub 2013 Apr 11. PMID: 23594489; PMCID: PMC3704173.
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Functional annotation of putative regulatory elements at cancer susceptibility Loci.

Cancer informatics

Rosse SA, Auer PL, Carlson CS.
PMID: 25288875
Cancer Inform. 2014 Sep 21;13:5-17. doi: 10.4137/CIN.S13789. eCollection 2014.

Most cancer-associated genetic variants identified from genome-wide association studies (GWAS) do not obviously change protein structure, leading to the hypothesis that the associations are attributable to regulatory polymorphisms. Translating genetic associations into mechanistic insights can be facilitated by knowledge...

Cite
Rosse SA, Auer PL, Carlson CS. Functional annotation of putative regulatory elements at cancer susceptibility Loci. Cancer Inform. 2014;13:5-17doi: 10.4137/CIN.S13789.
Rosse, S. A., Auer, P. L., & Carlson, C. S. (2014). Functional annotation of putative regulatory elements at cancer susceptibility Loci. Cancer informatics, 135-17. https://doi.org/10.4137/CIN.S13789
Rosse, Stephanie A, et al. "Functional annotation of putative regulatory elements at cancer susceptibility Loci." Cancer informatics vol. 13 (2014): 5-17. doi: https://doi.org/10.4137/CIN.S13789
Rosse SA, Auer PL, Carlson CS. Functional annotation of putative regulatory elements at cancer susceptibility Loci. Cancer Inform. 2014 Sep 21;13:5-17. doi: 10.4137/CIN.S13789. eCollection 2014. PMID: 25288875; PMCID: PMC4179605.
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