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Showing 1 to 12 of 15 entries
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Autonomic Imbalance and Risk of Dementia and Stroke: The Framingham Study.

Stroke

Weinstein G, Davis-Plourde K, Beiser AS, Seshadri S.
PMID: 33874747
Stroke. 2021 Jun;52(6):2068-2076. doi: 10.1161/STROKEAHA.120.030601. Epub 2021 Apr 20.

BACKGROUND AND PURPOSE: The autonomic nervous system has been implicated in stroke and dementia pathophysiology. High resting heart rate and low heart rate variability indicate the effect of autonomic imbalance on the heart. We examined the associations of resting...

Accelerometer-determined physical activity and cognitive function in middle-aged and older adults from two generations of the Framingham Heart Study.

Alzheimer's & dementia (New York, N. Y.)

Spartano NL, Demissie S, Himali JJ, Dukes KA, Murabito JM, Vasan RS, Beiser AS, Seshadri S.
PMID: 31660424
Alzheimers Dement (N Y). 2019 Oct 15;5:618-626. doi: 10.1016/j.trci.2019.08.007. eCollection 2019.

INTRODUCTION: Physical activity (PA) may play a role in maintenance of cognitive function in both middle and older ages and prevention of outcomes such as dementia and Alzheimer's disease.METHODS: Cross-sectional regression analyses were performed in Framingham Heart Study Third...

Autonomic Imbalance and Risk of Dementia and Stroke: The Framingham Study.

Stroke

Weinstein G, Davis-Plourde K, Beiser AS, Seshadri S.
PMID: 33874747
Stroke. 2021 Jun;52(6):2068-2076. doi: 10.1161/STROKEAHA.120.030601. Epub 2021 Apr 20.

[Figure: see text].

Association of circulating metabolites in plasma or serum and risk of stroke: Meta-analysis from seven prospective cohorts.

Neurology

Vojinovic D, Kalaoja M, Trompet S, Fischer K, Shipley MJ, Li S, Havulinna AS, Perola M, Salomaa V, Yang Q, Sattar N, Jousilahti P, Amin N, Satizabal CL, Taba N, Sabayan B, Vasan RS, Ikram MA, Stott DJ, Ala-Korpela M, Jukema JW, Seshadri S, Kettunen J, Kivimaki M, Esko T, van Duijn CM.
PMID: 33268560
Neurology. 2020 Dec 02; doi: 10.1212/WNL.0000000000011236. Epub 2020 Dec 02.

OBJECTIVE: To conduct a comprehensive analysis of circulating metabolites and incident stroke in large prospective population-based settings.METHODS: We investigated the association of metabolites with risk of stroke in seven prospective cohort studies including 1,791 incident stroke events among 38,797...

Multi-vendor and multisite evaluation of cerebrovascular reactivity mapping using hypercapnia challenge.

NeuroImage

Liu P, Jiang D, Albert M, Bauer CE, Caprihan A, Gold BT, Greenberg SM, Helmer KG, Jann K, Jicha G, Rodriguez P, Satizabal CL, Seshadri S, Singh H, Thompson JF, Wang DJJ, Lu H.
PMID: 34826595
Neuroimage. 2021 Dec 15;245:118754. doi: 10.1016/j.neuroimage.2021.118754. Epub 2021 Nov 23.

Cerebrovascular reactivity (CVR), which measures the ability of cerebral blood vessels to dilate or constrict in response to vasoactive stimuli such as CO2 inhalation, is an important index of the brain's vascular health. Quantification of CVR using BOLD MRI...

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.

Neurology

Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, Mazoyer B, Zhu YC, Kaffashian S, Schilling S, Beecham GW, Montine TJ, Schellenberg GD, Kjartansson O, Guðnason V, Knopman DS, Griswold ME, Windham BG, Gottesman RF, Mosley TH, Schmidt R, Saba Y, Schmidt H, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Rajan KB, Aggarwal NT, De Jager PL, Evans DA, Psaty BM, Rotter JI, Rice K, Lopez OL, Liao J, Chen C, Cheng CY, Wong TY, Ikram MK, van der Lee SJ, Amin N, Chouraki V, DeStefano AL, Aparicio HJ, Romero JR, Maillard P, DeCarli C, Wardlaw JM, Hernández MDCV, Luciano M, Liewald D, Deary IJ, Starr JM, Bastin ME, Muñoz Maniega S, Slagboom PE, Beekman M, Deelen J, Uh HW, Lemmens R, Brodaty H, Wright MJ, Ames D, Boncoraglio GB, Hopewell JC, Beecham AH, Blanton SH, Wright CB, Sacco RL, Wen W, Thalamuthu A, Armstrong NJ, Chong E, Schofield PR, Kwok JB, van der Grond J, Stott DJ, Ford I, Jukema JW, Vernooij MW, Hofman A, Uitterlinden AG, van der Lugt A, Wittfeld K, Grabe HJ, Hosten N, von Sarnowski B, Völker U, Levi C, Jimenez-Conde J, Sharma P, Sudlow CLM, Rosand J, Woo D, Cole JW, Meschia JF, Slowik A, Thijs V, Lindgren A, Melander O, Grewal RP, Rundek T, Rexrode K, Rothwell PM, Arnett DK, Jern C, Johnson JA, Benavente OR, Wasssertheil-Smoller S, Lee JM, Wong Q, Mitchell BD, Rich SS, McArdle PF, Geerlings MI, van der Graaf Y, de Bakker PIW, Asselbergs FW, Srikanth V, Thomson R, McWhirter R, Moran C, Callisaya M, Phan T, Rutten-Jacobs LCA, Bevan S, Tzourio C, Mather KA, Sachdev PS, van Duijn CM, Worrall BB, Dichgans M, Kittner SJ, Markus HS, Ikram MA, Fornage M, Launer LJ, Seshadri S, Longstreth WT, Debette S.
PMID: 30651383
Neurology. 2019 Jan 16; doi: 10.1212/WNL.0000000000006851. Epub 2019 Jan 16.

OBJECTIVE: To explore genetic and lifestyle risk factors of MRI-defined brain infarcts (BI) in large population-based cohorts.METHODS: We performed meta-analyses of genome-wide association studies (GWAS) and examined associations of vascular risk factors and their genetic risk scores (GRS) with...

Accelerometer-determined physical activity and cognitive function in middle-aged and older adults from two generations of the Framingham Heart Study.

Alzheimer's & dementia (New York, N. Y.)

Spartano NL, Demissie S, Himali JJ, Dukes KA, Murabito JM, Vasan RS, Beiser AS, Seshadri S.
PMID: 31660424
Alzheimers Dement (N Y). 2019 Oct 15;5:618-626. doi: 10.1016/j.trci.2019.08.007. eCollection 2019.

INTRODUCTION: Physical activity (PA) may play a role in maintenance of cognitive function in both middle and older ages and prevention of outcomes such as dementia and Alzheimer's disease.METHODS: Cross-sectional regression analyses were performed in Framingham Heart Study Third...

Association of circulating metabolites in plasma or serum and risk of stroke: Meta-analysis from seven prospective cohorts.

Neurology

Vojinovic D, Kalaoja M, Trompet S, Fischer K, Shipley MJ, Li S, Havulinna AS, Perola M, Salomaa V, Yang Q, Sattar N, Jousilahti P, Amin N, Satizabal CL, Taba N, Sabayan B, Vasan RS, Ikram MA, Stott DJ, Ala-Korpela M, Jukema JW, Seshadri S, Kettunen J, Kivimaki M, Esko T, van Duijn CM.
PMID: 33268560
Neurology. 2020 Dec 02; doi: 10.1212/WNL.0000000000011236. Epub 2020 Dec 02.

OBJECTIVE: To conduct a comprehensive analysis of circulating metabolites and incident stroke in large prospective population-based settings.METHODS: We investigated the association of metabolites with risk of stroke in seven prospective cohort studies including 1,791 incident stroke events among 38,797...

Accelerometer-determined physical activity and cognitive function in middle-aged and older adults from two generations of the Framingham Heart Study.

Alzheimer's & dementia (New York, N. Y.)

Spartano NL, Demissie S, Himali JJ, Dukes KA, Murabito JM, Vasan RS, Beiser AS, Seshadri S.
PMID: 31660424
Alzheimers Dement (N Y). 2019 Oct 15;5:618-626. doi: 10.1016/j.trci.2019.08.007. eCollection 2019.

INTRODUCTION: Physical activity (PA) may play a role in maintenance of cognitive function in both middle and older ages and prevention of outcomes such as dementia and Alzheimer's disease.METHODS: Cross-sectional regression analyses were performed in Framingham Heart Study Third...

Autonomic Imbalance and Risk of Dementia and Stroke: The Framingham Study.

Stroke

Weinstein G, Davis-Plourde K, Beiser AS, Seshadri S.
PMID: 33874747
Stroke. 2021 Jun;52(6):2068-2076. doi: 10.1161/STROKEAHA.120.030601. Epub 2021 Apr 20.

BACKGROUND AND PURPOSE: The autonomic nervous system has been implicated in stroke and dementia pathophysiology. High resting heart rate and low heart rate variability indicate the effect of autonomic imbalance on the heart. We examined the associations of resting...

Autonomic Imbalance and Risk of Dementia and Stroke: The Framingham Study.

Stroke

Weinstein G, Davis-Plourde K, Beiser AS, Seshadri S.
PMID: 33874747
Stroke. 2021 Jun;52(6):2068-2076. doi: 10.1161/STROKEAHA.120.030601. Epub 2021 Apr 20.

[Figure: see text].

Autonomic Imbalance and Risk of Dementia and Stroke: The Framingham Study.

Stroke

Weinstein G, Davis-Plourde K, Beiser AS, Seshadri S.
PMID: 33874747
Stroke. 2021 Jun;52(6):2068-2076. doi: 10.1161/STROKEAHA.120.030601. Epub 2021 Apr 20.

BACKGROUND AND PURPOSE: The autonomic nervous system has been implicated in stroke and dementia pathophysiology. High resting heart rate and low heart rate variability indicate the effect of autonomic imbalance on the heart. We examined the associations of resting...

Showing 1 to 12 of 15 entries