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Showing 1 to 12 of 20 entries
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Diazaborines Are a Versatile Platform to Develop ROS-Responsive Antibody Drug Conjugates*.

Angewandte Chemie (International ed. in English)

António JPM, Carvalho JI, André AS, Dias JNR, Aguiar SI, Faustino H, Lopes RMRM, Veiros LF, Bernardes GJL, da Silva FA, Gois PMP.
PMID: 34741376
Angew Chem Int Ed Engl. 2021 Dec 01;60(49):25914-25921. doi: 10.1002/anie.202109835. Epub 2021 Nov 05.

Antibody-drug conjugates (ADCs) are a new class of therapeutics that combine the lethality of potent cytotoxic drugs with the targeting ability of antibodies to selectively deliver drugs to cancer cells. In this study we show for the first time...

Selective Styrene Oxidation to Benzaldehyde over Recently Developed Heterogeneous Catalysts.

Molecules (Basel, Switzerland)

Andrade MA, Martins LMDRS.
PMID: 33802853
Molecules. 2021 Mar 17;26(6). doi: 10.3390/molecules26061680.

The selective oxidation of styrene under heterogeneous catalyzed conditions delivers environmentally friendly paths for the production of benzaldehyde, an important intermediate for the synthesis of several products. The present review explores heterogeneous catalysts for styrene oxidation using a variety...

Catalytic Performance of a Magnetic Core-Shell Iron(II) C-Scorpionate under Unconventional Oxidation Conditions.

Nanomaterials (Basel, Switzerland)

Matias IAS, Ribeiro APC, Ferraria AM, Rego AMBD, Martins LMDRS.
PMID: 33114194
Nanomaterials (Basel). 2020 Oct 23;10(11). doi: 10.3390/nano10112111.

For the first time, herein is reported the use of a magnetic core-shell support for a C-scorpionate metallic complex. The prepared hybrid material, that consists on the C-scorpionate iron(II) complex [FeCl

Resveratrol-Loaded Hydrogel Contact Lenses with Antioxidant and Antibiofilm Performance.

Pharmaceutics

Vivero-Lopez M, Muras A, Silva D, Serro AP, Otero A, Concheiro A, Alvarez-Lorenzo C.
PMID: 33920327
Pharmaceutics. 2021 Apr 11;13(4). doi: 10.3390/pharmaceutics13040532.

Contact lenses (CLs) are prone to biofilm formation, which may cause severe ocular infections. Since the use of antibiotics is associated with resistance concerns, here, two alternative strategies were evaluated to endow CLs with antibiofilm features: copolymerization with the...

Key Parameters on the Antibacterial Activity of Silver Camphor Complexes.

Antibiotics (Basel, Switzerland)

Costa JP, Sousa SA, Galvão AM, Mata JM, Leitão JH, Carvalho MFNN.
PMID: 33573154
Antibiotics (Basel). 2021 Jan 30;10(2). doi: 10.3390/antibiotics10020135.

Nine new complexes with camphor imine or camphor sulfonimine ligands were synthesized and analytically and spectroscopically characterized, aiming to identify the key parameters that drive the antibacterial activity of the complexes with metal cores and imine substituents with distinct...

Uranium Carbide Fibers with Nano-Grains as Starting Materials for ISOL Targets.

Nanomaterials (Basel, Switzerland)

Chowdhury S, Maria L, Cruz A, Manara D, Dieste-Blanco O, Stora T, Gonçalves AP.
PMID: 33316919
Nanomaterials (Basel). 2020 Dec 09;10(12). doi: 10.3390/nano10122458.

This paper presents an experimental study about the preparation, by electrospinning, of uranium carbide fibers with nanometric grain size. Viscous solutions of cellulose acetate and uranyl salts (acetate, acetylacetonate, and formate) on acetic acid and 2,4-pentanedione, adjusted to three...

Bioactive Coatings with Ag-Camphorimine Complexes to Prevent Surface Colonization by the Pathogenic Yeast .

Antibiotics (Basel, Switzerland)

Pinheiro MJF, Costa JP, Marques F, Mira NP, Carvalho MFNN, Alves MM.
PMID: 34073375
Antibiotics (Basel). 2021 May 26;10(6). doi: 10.3390/antibiotics10060638.

Currently there is a gap between the rate of new antifungal development and the emergence of resistance among

Phthalocyanine-Functionalized Magnetic Silica Nanoparticles as Anion Chemosensors.

Sensors (Basel, Switzerland)

Rodrigues JMM, Farinha ASF, Lin Z, Cavaleiro JAS, Tome AC, Tome JPC.
PMID: 33652615
Sensors (Basel). 2021 Feb 26;21(5). doi: 10.3390/s21051632.

Anionic species are one of the most common pollutants in residual and freshwaters. The presence of anthropogenic anions in water drastically increases the toxicity to living beings. Here, we report the preparation of a new optical active material based...

Noncovalent Interactions at Lanthanide Complexes.

Chemistry (Weinheim an der Bergstrasse, Germany)

Mahmudov KT, Huseynov FE, Aliyeva VA, Guedes da Silva MFC, Pombeiro AJL.
PMID: 34363268
Chemistry. 2021 Oct 19;27(58):14370-14389. doi: 10.1002/chem.202102245. Epub 2021 Sep 16.

Lanthanide complexes have attracted a widespread attention due to their structural diversity, as well as multifunctional and tunable properties. The development of lanthanide based functional materials has often relied on the design of the secondary coordination sphere of the...

Atorvastatin-Eluting Contact Lenses: Effects of Molecular Imprinting and Sterilization on Drug Loading and Release.

Pharmaceutics

Pereira-da-Mota AF, Vivero-Lopez M, Topete A, Serro AP, Concheiro A, Alvarez-Lorenzo C.
PMID: 33922123
Pharmaceutics. 2021 Apr 22;13(5). doi: 10.3390/pharmaceutics13050606.

Statins are receiving increasing attention in the ophthalmic field. Their activity as 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inhibitors is clinically used to regulate cholesterol levels and leads to pleiotropic effects, which may help in the management of diabetes-related ocular pathologies. This...

Novel H-Bonded Synthons in Copper Supramolecular Frameworks with Aminoethylpiperazine-Based Ligands. Synthesis, Structure and Catalytic Activity.

Materials (Basel, Switzerland)

Nesterova OV, Pombeiro AJL, Nesterov DS.
PMID: 33260358
Materials (Basel). 2020 Nov 29;13(23). doi: 10.3390/ma13235435.

New Schiff base complexes [Cu

Biobased Ionic Liquids as Multitalented Materials in Lipidic Drug Implants.

Pharmaceutics

Júlio A, Sultane A, Viana AS, Mota JP, Santos de Almeida T.
PMID: 34452124
Pharmaceutics. 2021 Jul 28;13(8). doi: 10.3390/pharmaceutics13081163.

Lipidic implants are valuable controlled delivery systems that present good biocompatibility and are useful for long-lasting therapies. However, these promising systems can present inflexible drug release profiles that limit their performance. Thus, finding new materials to overcome this drawback...

Showing 1 to 12 of 20 entries