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Showing 1 to 12 of 47 entries
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Extracting Electronic Health Record Data in a Practice-Based Research Network: Processes to Support Translational Research across Diverse Practice Organizations.

EGEMS (Washington, DC)

Cole AM, Stephens KA, Keppel GA, Estiri H, Baldwin LM.
PMID: 27141519
EGEMS (Wash DC). 2016 Mar 29;4(2):1206. doi: 10.13063/2327-9214.1206. eCollection 2016.

CONTEXT: The widespread adoption of electronic health records (EHRs) offers significant opportunities to conduct research with clinical data from patients outside traditional academic research settings. Because EHRs are designed primarily for clinical care and billing, significant challenges are inherent...

Immune Responses to rAAV6: The Influence of Canine Parvovirus Vaccination and Neonatal Administration of Viral Vector.

Frontiers in microbiology

Arnett AL, Garikipati D, Wang Z, Tapscott S, Chamberlain JS.
PMID: 22065964
Front Microbiol. 2011 Nov 03;2:220. doi: 10.3389/fmicb.2011.00220. eCollection 2011.

Recombinant adeno-associated viral (rAAV) vectors promote long-term gene transfer in many animal species. Significant effort has focused on the evaluation of rAAV delivery and the immune response in both murine and canine models of neuromuscular disease. However, canines provided...

Participant-Centric Initiatives: Tools to Facilitate Engagement In Research.

Applied & translational genomics

Anderson N, Bragg C, Hartzler A, Edwards K.
PMID: 24772384
Appl Transl Genom. 2012 Dec 01;1:25-29. doi: 10.1016/j.atg.2012.07.001.

Clinical genomic research faces increasing challenges in establishing participant privacy and consent processes that facilitate meaningful choice and communication capacity for longitudinal and secondary research uses. There are an evolving range of participant-centric initiatives that combine web-based informatics tools...

Parental Catastrophizing Partially Mediates the Association between Parent-Reported Child Pain Behavior and Parental Protective Responses.

Pain research and treatment

Langer SL, Romano JM, Mancl L, Levy RL.
PMID: 24579047
Pain Res Treat. 2014;2014:751097. doi: 10.1155/2014/751097. Epub 2014 Jan 20.

This study sought to model and test the role of parental catastrophizing in relationship to parent-reported child pain behavior and parental protective (solicitous) responses to child pain in a sample of children with Inflammatory Bowel Disease and their parents...

Program evaluation of Sea Mar's Chronic Care Program for Latino and Caucasian patients with type 2 diabetes: providers and staff perspectives.

Journal of multidisciplinary healthcare

Bond GE, Rechholtz L, Bosa C, Impert C, Barker S.
PMID: 23055743
J Multidiscip Healthc. 2012;5:241-8. doi: 10.2147/JMDH.S35489. Epub 2012 Sep 27.

PROBLEM STATEMENT: Unprecedented consumption of health care resources in the USA coupled with increasing rates of chronic disease has fueled pursuit of improved models of health care delivery. The Chronic Care Model provides an organizational framework for chronic care...

Starting the Conversation - A Childhood Obesity Knowledge Project Using an App.

British journal of medicine and medical research

Appel HB, Huang B, Cole A, James R, Ai AL.
PMID: 24678462
Br J Med Med Res. 2014 Apr 01;4(7):1526-1538. doi: 10.9734/bjmmr/2014/5512.

METHODS: The study was conducted in 2011-2012. The sample, recruited from seven high schools in Snohomish County, Washington, was 65.3% minority participants. Of the 118 participants in the sample (n=118), 79 handwrote their responses (n=78) and 36 responded via...

Personalized medicine: challenges and opportunities for translational bioinformatics.

Personalized medicine

Overby CL, Tarczy-Hornoch P.
PMID: 24039624
Per Med. 2013 Jul 01;10(5):453-462. doi: 10.2217/pme.13.30.

Personalized medicine can be defined broadly as a model of healthcare that is predictive, personalized, preventive and participatory. Two US President's Council of Advisors on Science and Technology reports illustrate challenges in personalized medicine (in a 2008 report) and...

Initial development and pilot testing of observer-reported outcomes (ObsROs) for children with cystic fibrosis ages 0-11years.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society

Edwards TC, Emerson J, Genatossio A, McNamara S, Goss C, Patrick DL, Onchiri F, Rosenfeld M.
PMID: 29358075
J Cyst Fibros. 2018 Sep;17(5):680-686. doi: 10.1016/j.jcf.2017.12.008. Epub 2018 Feb 01.

PURPOSE: Patient-reported outcomes are important clinical trial endpoints. Young children may not be able to reliably report on how they feel or function, so observer-reported outcomes (ObsROs) may be more appropriate for them. The purpose of this study was...

Racial and socioeconomic disparities in the efficacy of a family-based treatment programme for paediatric obesity.

Pediatric obesity

Davison GM, Fowler LA, Ramel M, Stein RI, Conlon RPK, Saelens BE, Welch RR, Perri MG, Epstein LH, Wilfley DE.
PMID: 33847074
Pediatr Obes. 2021 Oct;16(10):e12792. doi: 10.1111/ijpo.12792. Epub 2021 Apr 12.

BACKGROUND: Family-based behavioural weight loss treatment (FBT) is an evidence-based intervention for paediatric overweight/obesity (OV/OB), but little research has examined the relative efficacy of FBT across socioeconomic status (SES), and racial groups.METHOD: A total of 172 youth (7-11 years;...

A Phase II Study Evaluating the Safety and Efficacy of Sunitinib Malate in Combination With Weekly Paclitaxel Followed by Doxorubicin and Daily Oral Cyclophosphamide Plus G-CSF as Neoadjuvant Chemotherapy for Locally Advanced or Inflammatory Breast Cancer.

Clinical breast cancer

Symonds L, Jenkins I, Linden HM, Kurland B, Gralow JR, Gadi VVK, Ellis GK, Wu Q, Rodler E, Chalasani P, Chai X, Riedel J, Scca Network Investigators, Stopeck A, Brown-Glaberman U, Specht JM.
PMID: 34158245
Clin Breast Cancer. 2022 Jan;22(1):32-42. doi: 10.1016/j.clbc.2021.05.009. Epub 2021 May 24.

INTRODUCTION: Neoadjuvant chemotherapy is standard treatment for locally advanced breast cancer (LABC) or inflammatory breast cancer (IBC). We hypothesized that adding sunitinib, a tyrosine kinase inhibitor with antitumor and antiangiogenic activity, to an anthracycline and taxane regimen would improve...

Most Early-Treated Children With Perinatally Acquired HIV Have Preserved Lung Function at School Age.

Journal of acquired immune deficiency syndromes (1999)

Attia EF, Moraa H, Maleche-Obimbo E, Wamalwa D, Gómez LA, Rylance S, Vundla R, Ferrand RA, Karr CJ, John-Stewart GC, Benki-Nugent SF.
PMID: 34878436
J Acquir Immune Defic Syndr. 2022 Jan 01;89(1):69-76. doi: 10.1097/QAI.0000000000002823.

BACKGROUND: Impaired lung function is common among older children with perinatally acquired HIV (PHIV) who initiated antiretroviral therapy (ART) late in childhood. We determined the prevalence of abnormal spirometry and cofactors for impaired lung function among school-age children with...

Racial and socioeconomic disparities in the efficacy of a family-based treatment programme for paediatric obesity.

Pediatric obesity

Davison GM, Fowler LA, Ramel M, Stein RI, Conlon RPK, Saelens BE, Welch RR, Perri MG, Epstein LH, Wilfley DE.
PMID: 33847074
Pediatr Obes. 2021 Oct;16(10):e12792. doi: 10.1111/ijpo.12792. Epub 2021 Apr 12.

BACKGROUND: Family-based behavioural weight loss treatment (FBT) is an evidence-based intervention for paediatric overweight/obesity (OV/OB), but little research has examined the relative efficacy of FBT across socioeconomic status (SES), and racial groups.METHOD: A total of 172 youth (7-11 years;...

Showing 1 to 12 of 47 entries