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Speech recognition across the lifespan: Longitudinal changes from middle age to older adults.

American journal of audiology

Dubno JR.
PMID: 25767998
Am J Audiol. 2015 Jun;24(2):84-87. doi: 10.1044/2015_AJA-14-0052. Epub 2015 Mar 12.

PURPOSE: To provide an overview of evidence of age-related declines in speech recognition in middle-age to older adults, review contributions of pure-tone thresholds, age, and gender, and report preliminary results from a longitudinal study.METHODS: Pure-tone thresholds and word recognition...

Fibrocytes in the fibrotic lung: altered phenotype detected by flow cytometry.

Frontiers in pharmacology

Reese C, Lee R, Bonner M, Perry B, Heywood J, Silver RM, Tourkina E, Visconti RP, Hoffman S.
PMID: 24999331
Front Pharmacol. 2014 Jun 16;5:141. doi: 10.3389/fphar.2014.00141. eCollection 2014.

Fibrocytes are bone marrow hematopoietic-derived cells that also express a mesenchymal cell marker (commonly collagen I) and participate in fibrotic diseases of multiple organs. Given their origin, they or their precursors must be circulating cells before recruitment into target...

Stress and Depression in Relation to Functional Health Behaviors in African American Patients with Systemic Lupus Erythematosus.

Rheumatology (Sunnyvale, Calif.)

Williams EM, Bruner L, Penfield M, Kamen D, Oates JC.
PMID: 26618072
Rheumatology (Sunnyvale). 2014;2014. doi: 10.4172/2161-1149.S4-005. Epub 2014 Nov 07.

OBJECTIVE: While increased psychological distress in SLE has been clinically and empirically reported, the relationship between emotional distress, treatment adherence, and disease activity are complex and even more unclear in African American lupus patients. In an effort to elucidate...

The Mouse Round-window Approach for Ototoxic Agent Delivery: A Rapid and Reliable Technique for Inducing Cochlear Cell Degeneration.

Journal of visualized experiments : JoVE

Stevens SM, Brown LN, Ezell PC, Lang H.
PMID: 26650771
J Vis Exp. 2015 Nov 26;(105). doi: 10.3791/53131.

Investigators have utilized a wide array of animal models and investigative techniques to study the mammalian auditory system. Much of the basic research involving the cochlea and its associated neural pathways entails exposure of model cochleae to a variety...

Caveolin-1 regulates chemokine receptor 5-mediated contribution of bone marrow-derived cells to dermal fibrosis.

Frontiers in pharmacology

Lee R, Perry B, Heywood J, Reese C, Bonner M, Hatfield CM, Silver RM, Visconti RP, Hoffman S, Tourkina E.
PMID: 24966836
Front Pharmacol. 2014 Jun 11;5:140. doi: 10.3389/fphar.2014.00140. eCollection 2014.

In fibrotic diseases caveolin-1 underexpression in fibroblasts results in collagen overexpression and in monocytes leads to hypermigration. These profibrotic behaviors are blocked by the caveolin-1 scaffolding domain peptide (CSD) which compensates for caveolin-1 deficiency. Monocytes and fibroblasts are related...

Cyclophosphamide Induces an Early Wave of Acrolein-Independent Apoptosis in the Urothelium.

Advances in bioscience and biotechnology (Print)

Hughes FM, Corn AG, Nimmich AR, Pratt-Thomas JD, Purves JT.
PMID: 24353901
Adv Biosci Biotechnol. 2013 Aug;4(88). doi: 10.4236/abb.2013.48A2002.

PURPOSE: Hemorrhagic cystitis (HC or bladder inflammation) affects a significant number of patients undergoing cyclophosphamide (CP) chemotherapy despite treatment with 2-mercaptoMATERIALS AND METHODS: Apoptosis in urothelium (caspase-3/7 activity and Poly (ADP-ribosyl) polymerase (PARP) cleavage) was measured following CP administration...

Pilot Study and Review: Physiological Differences in BDNF, a Potential Biomarker in Males and Females with Autistic Disorder.

International neuropsychiatric disease journal

Spratt EG, Granholm AC, Carpenter LA, Boger HA, Papa CE, Logan S, Chaudhary H, Boatwright SW, Brady KT.
PMID: 26866045
Int Neuropsychiatr Dis J. 2015;3(1):19-26. doi: 10.9734/INDJ/2015/12118. Epub 2014 Sep 24.

AIMS: There is a need for more biologic research in autistic disorder (AD) to determine if biomarkers exist that would be useful for correlating to symptom severity and/or clinical improvement during treatment. Given the fact that AD is 4...

The role of 2,4-dihydroxyquinoline (DHQ) in Pseudomonas aeruginosa pathogenicity.

PeerJ

Gruber JD, Chen W, Parnham S, Beauchesne K, Moeller P, Flume PA, Zhang YM.
PMID: 26788419
PeerJ. 2016 Jan 07;4:e1495. doi: 10.7717/peerj.1495. eCollection 2016.

Bacteria synchronize group behaviors using quorum sensing, which is advantageous during an infection to thwart immune cell attack and resist deleterious changes in the environment. In Pseudomonas aeruginosa, the Pseudomonas quinolone signal (Pqs) quorum-sensing system is an important component...

Evaluation of an mHealth Medication Regimen Self-Management Program for African American and Hispanic Uncontrolled Hypertensives.

Journal of personalized medicine

Davidson TM, McGillicuddy J, Mueller M, Brunner-Jackson B, Favella A, Anderson A, Torres M, Ruggiero KJ, Treiber FA.
PMID: 26593951
J Pers Med. 2015 Nov 17;5(4):389-405. doi: 10.3390/jpm5040389.

African Americans and Hispanics have disproportionate rates of uncontrolled essential hypertension (EH) compared to Non-Hispanic Whites. Medication non-adherence (MNA) is the leading modifiable behavior to improved blood pressure (BP) control. The Smartphone Medication Adherence Stops Hypertension (SMASH) program was...

Genes associated with SLE are targets of recent positive selection.

Autoimmune diseases

Ramos PS, Shaftman SR, Ward RC, Langefeld CD.
PMID: 24587899
Autoimmune Dis. 2014;2014:203435. doi: 10.1155/2014/203435. Epub 2014 Jan 23.

The reasons for the ethnic disparities in the prevalence of systemic lupus erythematosus (SLE) and the relative high frequency of SLE risk alleles in the population are not fully understood. Population genetic factors such as natural selection alter allele...

New insights into the vitamin D requirements during pregnancy.

Bone research

Hollis BW, Wagner CL.
PMID: 28868163
Bone Res. 2017 Aug 29;5:17030. doi: 10.1038/boneres.2017.30. eCollection 2017.

Pregnancy represents a dynamic period with physical and physiological changes in both the mother and her developing fetus. The dramatic 2-3 fold increase in the active hormone 1,25(OH)

Newborn Screening for Sickle Cell Disease in St. Vincent and the Grenadines: Results of a Pilot Newborn Screening Program.

Global pediatric health

Williams SA, Browne-Ferdinand B, Smart Y, Morella K, Reed SG, Kanter J.
PMID: 29147675
Glob Pediatr Health. 2017 Nov 03;4:2333794X17739191. doi: 10.1177/2333794X17739191. eCollection 2017.

No abstract available.

Showing 1 to 12 of 110 entries