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Showing 1 to 12 of 65 entries
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A survey of practices for the use of electronic health records to support research recruitment.

Journal of clinical and translational science

Obeid JS, Beskow LM, Rape M, Gouripeddi R, Black RA, Cimino JJ, Embi PJ, Weng C, Marnocha R, Buse JB.
PMID: 29657859
J Clin Transl Sci. 2017 Aug;1(4):246-252. doi: 10.1017/cts.2017.301.

Electronic health records (EHRs) provide great promise for identifying cohorts and enhancing research recruitment. Such approaches are sorely needed, but there are few descriptions in the literature of prevailing practices to guide their use. A multidisciplinary workgroup was formed...

Ruxolitinib for treatment of refractory hemophagocytic lymphohistiocytosis.

Blood advances

Broglie L, Pommert L, Rao S, Thakar M, Phelan R, Margolis D, Talano J.
PMID: 29296794
Blood Adv. 2017 Aug 17;1(19):1533-1536. doi: 10.1182/bloodadvances.2017007526. eCollection 2017 Aug 22.

Optimal salvage therapy for refractory HLH is unknown.In our patient, ruxolitinib treatment led to clinical remission of refractory HLH.

Differences in fatigability of muscles involved in fecal continence: Potential clinical ramifications.

Physiological reports

Patel K, Mei L, Yu E, Kern M, Lehal N, Edeani F, Sanvanson P, Davidson ERW, Shaker R.
PMID: 34927399
Physiol Rep. 2021 Dec;9(24):e15144. doi: 10.14814/phy2.15144.

INTRODUCTION: Fatigue of the anal sphincter complex has been demonstrated using high-resolution anorectal manometry (HRAM). However, the fatigability of individual muscles such as the external anal sphincter (EAS) and puborectalis muscles (PRM) has not been described. Vaginal manometry has...

An integrative healthcare model with heartfulness meditation and care coordination improves outcomes in cyclic vomiting syndrome.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society

Venkatesan T, Porcelli A, Matapurkar A, Suresh Kumar VC, Szabo A, Yin Z, Wieloch L.
PMID: 33774892
Neurogastroenterol Motil. 2021 Nov;33(11):e14132. doi: 10.1111/nmo.14132. Epub 2021 Mar 28.

BACKGROUND: Cyclic vomiting syndrome (CVS) is associated with psychosocial comorbidity and often triggered by stress. Since the current disease-centered care model does not address psychosocial factors, we hypothesized that holistic, patient-centered care integrating meditation and addressing psychosocial needs through...

Comparing Traumatic Brain Injury Symptoms Reported via Questionnaires Versus a Novel Structured Interview.

Journal of the International Neuropsychological Society : JINS

Emmert NA, Ristow G, McCrea MA, deRoon-Cassini TA, Nelson LD.
PMID: 33752775
J Int Neuropsychol Soc. 2021 Mar 23;1-11. doi: 10.1017/S1355617721000278. Epub 2021 Mar 23.

OBJECTIVE: Mild traumatic brain injury (mTBI) symptoms are typically assessed via questionnaires in research, yet questionnaires may be more prone to biases than direct clinical interviews. We compared mTBI symptoms reported on two widely used self-report inventories and the...

Hypertriglyceridemia during hospitalization independently associates with mortality in patients with COVID-19.

Journal of clinical lipidology

Dai W, Lund H, Chen Y, Zhang J, Osinski K, Jones SZ, Kreuziger LB, López JA, Benjamin IJ, Silverstein RL, Zheng Z.
PMID: 34470719
J Clin Lipidol. 2021 Sep-Oct;15(5):724-731. doi: 10.1016/j.jacl.2021.08.002. Epub 2021 Aug 10.

BACKGROUND: Alteration in blood triglyceride levels have been found in patients with coronavirus disease 2019 (COVID-19). However, the association between hypertriglyceridemia and mortality in COVID-19 patients is unknown.OBJECTIVE: To investigate the association between alteration in triglyceride level and mortality...

Assessing Retinal Structure in Patients with Parkinson's Disease.

Journal of neurology & neurophysiology

Young JB, Godara P, Williams V, Summerfelt P, Connor TB, Tarima S, Visotcky A, Cooper RF, Blindauer K, Carroll J.
PMID: 31057987
J Neurol Neurophysiol. 2019;10(1). doi: 10.4172/2155-9562.1000485. Epub 2019 Mar 07.

OBJECTIVE: The retina is an extension of the central nervous system (CNS), and ocular symptoms can precede manifestations of CNS disorders. Given that several neurodegenerative conditions that affect the brain exhibit ocular symptoms, the retina may be an accessible...

The effect of number of healthcare visits on study sample selection in electronic health record data.

International journal of population data science

Rasmussen-Torvik LJ, Furmanchuk A, Stoddard AJ, Osinski KI, Meurer JR, Smith N, Chrischilles E, Black BS, Kho A.
PMID: 32864475
Int J Popul Data Sci. 2020;5(1). doi: 10.23889/ijpds.v5i1.1156. Epub 2020 Apr 02.

INTRODUCTION: Few studies have addressed how to select a study sample when using electronic health record (EHR) data.OBJECTIVE: To examine how changing criterion for number of visits in EHR data required for inclusion in a study sample would impact...

Contractility of Induced Pluripotent Stem Cell-Cardiomyocytes With an .

Frontiers in cell and developmental biology

Kim MS, Fleres B, Lovett J, Anfinson M, Samudrala SSK, Kelly LJ, Teigen LE, Cavanaugh M, Marquez M, Geurts AM, Lough JW, Mitchell ME, Fitts RH, Tomita-Mitchell A.
PMID: 32656206
Front Cell Dev Biol. 2020 Jun 23;8:440. doi: 10.3389/fcell.2020.00440. eCollection 2020.

Hypoplastic left heart syndrome (HLHS) is a clinically and anatomically severe form of congenital heart disease; however, its etiology remains largely unknown. We previously demonstrated that genetic variants in the

Science Cafés: Transforming citizens to scientific citizens-What influences participants' perceived change in health and scientific literacy?.

Journal of clinical and translational science

Ahmed SM, DeFino M, Connors E, Visotcky A, Kissack A, Franco Z.
PMID: 28649455
J Clin Transl Sci. 2017 Apr;1(2):129-134. doi: 10.1017/cts.2016.24. Epub 2017 Apr 19.

INTRODUCTION: Science Cafés facilitated by the Clinical and Translational Science Institute of Southeast Wisconsin seek to increase health and scientific literacy through informal conversation between researchers and community members. The goal was to understand what factors have the greatest...

Reduced Prothrombinase Inhibition by Tissue Factor Pathway Inhibitor Contributes to the Factor V Leiden Hypercoagulable State.

Blood advances

Wood JP, Baumann Kreuziger LM, Ellery PER, Maroney SA, Mast AE.
PMID: 28580443
Blood Adv. 2017 Feb 14;1(6):386-395. doi: 10.1182/bloodadvances.2016002295.

Activated factor V (FVa) and factor X (FXa) form prothrombinase, which converts prothrombin to thrombin. The α isoform of tissue factor (TF) pathway inhibitor (TFPI) dampens early procoagulant events, partly by interacting with FV. FV Leiden (FVL) is the...

IPI59: An Actionable Biomarker to Improve Treatment Response in Serous Ovarian Carcinoma Patients.

Statistics in biosciences

Choi J, Ye S, Eng KH, Korthauer K, Bradley WH, Rader JS, Kendziorski C.
PMID: 28966695
Stat Biosci. 2017 Jun;9(1):1-12. doi: 10.1007/s12561-016-9144-1. Epub 2016 Mar 29.

Despite improvements in operative management and therapies, overall survival rates in advanced ovarian cancer have remained largely unchanged over the past three decades. Although it is possible to identify high-risk patients following surgery, the knowledge does not provide information...

Showing 1 to 12 of 65 entries