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Showing 1 to 12 of 350 entries
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Germline whole exome sequencing and large-scale replication identifies .

Oncotarget

Dicks E, Song H, Ramus SJ, Oudenhove EV, Tyrer JP, Intermaggio MP, Kar S, Harrington P, Bowtell DD, Group AS, Cicek MS, Cunningham JM, Fridley BL, Alsop J, Jimenez-Linan M, Piskorz A, Goranova T, Kent E, Siddiqui N, Paul J, Crawford R, Poblete S, Lele S, Sucheston-Campbell L, Moysich KB, Sieh W, McGuire V, Lester J, Odunsi K, Whittemore AS, Bogdanova N, Dürst M, Hillemanns P, Karlan BY, Gentry-Maharaj A, Menon U, Tischkowitz M, Levine D, Brenton JD, Dörk T, Goode EL, Gayther SA, Pharoah DPP.
PMID: 28881617
Oncotarget. 2017 Mar 03;8(31):50930-50940. doi: 10.18632/oncotarget.15871. eCollection 2017 Aug 01.

We analyzed whole exome sequencing data in germline DNA from 412 high grade serous ovarian cancer (HGSOC) cases from The Cancer Genome Atlas Project and identified 5,517 genes harboring a predicted deleterious germline coding mutation in at least one...

Gastrointestinal symptoms among ambulatory HIV patients: appropriate symptom management requires improved symptom recognition.

Annals of gastroenterology

Kelesidis T.
PMID: 24714135
Ann Gastroenterol. 2012;25(3):186-187.

No abstract available.

A survey of practices for the use of electronic health records to support research recruitment.

Journal of clinical and translational science

Obeid JS, Beskow LM, Rape M, Gouripeddi R, Black RA, Cimino JJ, Embi PJ, Weng C, Marnocha R, Buse JB.
PMID: 29657859
J Clin Transl Sci. 2017 Aug;1(4):246-252. doi: 10.1017/cts.2017.301.

Electronic health records (EHRs) provide great promise for identifying cohorts and enhancing research recruitment. Such approaches are sorely needed, but there are few descriptions in the literature of prevailing practices to guide their use. A multidisciplinary workgroup was formed...

Variation in Mutant Prevention Concentrations.

Frontiers in microbiology

Gianvecchio C, Lozano NA, Henderson C, Kalhori P, Bullivant A, Valencia A, Su L, Bello G, Wong M, Cook E, Fuller L, Neal JB, Yeh PJ.
PMID: 30766517
Front Microbiol. 2019 Jan 31;10:42. doi: 10.3389/fmicb.2019.00042. eCollection 2019.

No abstract available.

Bivariate Genome-Wide Association Study of Depressive Symptoms With Type 2 Diabetes and Quantitative Glycemic Traits.

Psychosomatic medicine

Haljas K, Amare AT, Alizadeh BZ, Hsu YH, Mosley T, Newman A, Murabito J, Tiemeier H, Tanaka T, van Duijn C, Ding J, Llewellyn DJ, Bennett DA, Terracciano A, Launer L, Ladwig KH, Cornelis MC, Teumer A, Grabe H, Kardia SLR, Ware EB, Smith JA, Snieder H, Eriksson JG, Groop L, Räikkönen K, Lahti J.
PMID: 29280852
Psychosom Med. 2018 Apr;80(3):242-251. doi: 10.1097/PSY.0000000000000555.

OBJECTIVE: Shared genetic background may explain phenotypic associations between depression and Type 2 diabetes (T2D). We aimed to study, on a genome-wide level, if genetic correlation and pleiotropic loci exist between depressive symptoms and T2D or glycemic traits.METHODS: We...

Weight Bearing Over-ground Stepping in an Exoskeleton with Non-invasive Spinal Cord Neuromodulation after Motor Complete Paraplegia.

Frontiers in neuroscience

Gad P, Gerasimenko Y, Zdunowski S, Turner A, Sayenko D, Lu DC, Edgerton VR.
PMID: 28642680
Front Neurosci. 2017 Jun 08;11:333. doi: 10.3389/fnins.2017.00333. eCollection 2017.

We asked whether coordinated voluntary movement of the lower limbs could be regained in an individual having been completely paralyzed (>4 year) and completely absent of vision (>15 year) using two novel strategies-transcutaneous electrical spinal cord stimulation at selected...

Microgeographic Proteomic Networks of the Human Colonic Mucosa and Their Association With Inflammatory Bowel Disease.

Cellular and molecular gastroenterology and hepatology

Li X, LeBlanc J, Elashoff D, McHardy I, Tong M, Roth B, Ippoliti A, Barron G, McGovern D, McDonald K, Newberry R, Graeber T, Horvath S, Goodglick L, Braun J.
PMID: 28174738
Cell Mol Gastroenterol Hepatol. 2016 May 17;2(5):567-583. doi: 10.1016/j.jcmgh.2016.05.003. eCollection 2016 Sep.

BACKGROUND & AIMS: Interactions between mucosal cell types, environmental stressors, and intestinal microbiota contribute to pathogenesis in inflammatory bowel disease (IBD). Here, we applied metaproteomics of the mucosal-luminal interface to study the disease-related biology of the human colonic mucosa.METHODS:...

Application of Low-Cost, Easy-to-Use, Portable Biosensor Systems for Diagnosing Bladder Dysfunctions.

International neurourology journal

Myung NV, Jung S, Kim J.
PMID: 30943698
Int Neurourol J. 2019 Mar;23(1):86-87. doi: 10.5213/inj.1938020.010. Epub 2019 Mar 31.

No abstract available.

Depression in Nonclassical Hypogonadism in Young Men.

Journal of the Endocrine Society

Korenman SG, Grotts JF, Bell DS, Elashoff DA.
PMID: 30430144
J Endocr Soc. 2018 Sep 21;2(11):1306-1313. doi: 10.1210/js.2018-00137. eCollection 2018 Nov 01.

The specific objective of this study was to test the clinically derived hypothesis associating a high prevalence of depression in young men with nonclassical hypogonadism. We studied the entire population of men aged 18 to 40 years who had...

A Comparison of the Liver Fat Score and CT Liver-to-Spleen Ratio as Predictors of Fatty Liver Disease by HIV Serostatus.

Journal of clinical gastroenterology and hepatology

Mellor-Crummey LE, Lake JE, Wilhalme H, Tseng CH, Grant PM, Erlandson KM, Price JC, Palella FJ, Kingsley LA, Budoff M, Post WS, Brown TT.
PMID: 30511049
J Clin Gastroenterol Hepatol. 2018;2(3). doi: 10.21767/2575-7733.1000045. Epub 2018 Jul 30.

BACKGROUND AND AIM: Non-alcoholic fatty liver disease (NAFLD) is common among HIV-infected (HIV+) adults. The Liver Fat Score (LFS) is a non-invasive, rapid, inexpensive diagnostic tool that uses routine clinical data and is validated against biopsy in HIV-uninfected (HIV-)...

A protocol integrating remote patient monitoring patient reported outcomes and cardiovascular biomarkers.

NPJ digital medicine

Shufelt C, Dzubur E, Joung S, Fuller G, Mouapi KN, Van Den Broek I, Lopez M, Dhawan S, Arnold CW, Speier W, Mastali M, Fu Q, Van Eyk JE, Spiegel B, Merz CNB.
PMID: 31508495
NPJ Digit Med. 2019 Sep 03;2:84. doi: 10.1038/s41746-019-0145-6. eCollection 2019.

We describe the protocol, design, and methodology of the Prediction, Risk, and Evaluation of Major Adverse Cardiac Events (PRE-MACE) study as a multicomponent remote patient monitoring in cardiology. Using biosensor, biomarkers, and patient-reported outcomes in participants with stable ischemic...

Functional Limitations, Volunteering, and Diurnal Cortisol Patterns in Older Adults.

The journals of gerontology. Series B, Psychological sciences and social sciences

Huo M, Han SH, Kim K, Choi J.
PMID: 32692814
J Gerontol B Psychol Sci Soc Sci. 2021 Oct 30;76(9):1893-1903. doi: 10.1093/geronb/gbaa104.

OBJECTIVES: Older adults often experience functional limitations that affect their everyday lives, but many of them continue to make positive contributions to society and benefit from these contributions themselves. We examine (a) whether older adults' functional limitations are associated...

Showing 1 to 12 of 350 entries