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Showing 1 to 12 of 43 entries
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Fecal Microbiota Transplant for Refractory .

Open forum infectious diseases

Wang T, Kraft CS, Woodworth MH, Dhere T, Eaton ME.
PMID: 29450212
Open Forum Infect Dis. 2018 Jan 15;5(2):ofy016. doi: 10.1093/ofid/ofy016. eCollection 2018 Feb.

No abstract available.

The Antibacterial Resistance Leadership Group: First Steps.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Murray BE, Jezek A.
PMID: 28350895
Clin Infect Dis. 2017 Mar 15;64:S1-S2. doi: 10.1093/cid/ciw823.

No abstract available.

Group-Sequential Strategies in Clinical Trials with Multiple Co-Primary Outcomes.

Statistics in biopharmaceutical research

Hamasaki T, Asakura K, Evans SR, Sugimoto T, Sozu T.
PMID: 25844122
Stat Biopharm Res. 2015;7(1):36-54. doi: 10.1080/19466315.2014.1003090.

We discuss the decision-making frameworks for clinical trials with multiple co-primary endpoints in a group-sequential setting. The decision-making frameworks can account for flexibilities such as a varying number of analyses, equally or unequally spaced increments of information and fixed...

Polymyxins: To Combine or Not to Combine?.

Antibiotics (Basel, Switzerland)

Perez F, El Chakhtoura NG, Yasmin M, Bonomo RA.
PMID: 30974813
Antibiotics (Basel). 2019 Apr 10;8(2). doi: 10.3390/antibiotics8020038.

Polymyxins have been a mainstay for the treatment of extensively drug resistant (XDR) Gram-negative bacteria for the past two decades. Many questions regarding the clinical use of polymyxins have been answered, but whether the administration of polymyxins in combination...

Emergence of Resistance to Colistin During the Treatment of Bloodstream Infection Caused by .

Open forum infectious diseases

Kanwar A, Marshall SH, Perez F, Tomas M, Jacobs MR, Hujer AM, Domitrovic TN, Rudin SD, Rojas LJ, Kreiswirth BN, Chen L, Quinones-Mateu M, van Duin D, Bonomo RA.
PMID: 30014001
Open Forum Infect Dis. 2018 Apr 23;5(4):ofy054. doi: 10.1093/ofid/ofy054. eCollection 2018 Apr.

We report the emergence of colistin resistance in

Can the Ceftriaxone Breakpoints Be Increased Without Compromising Patient Outcomes?.

Open forum infectious diseases

Tamma PD, Pierce VM, Cosgrove SE, Lautenbach E, Harris A, Rayapati D, Han JH.
PMID: 29992175
Open Forum Infect Dis. 2018 Jun 08;5(6):ofy139. doi: 10.1093/ofid/ofy139. eCollection 2018 Jun.

BACKGROUND: In 2010, the Clinical Laboratory and Standards Institute recommended a 3-fold lowering of ceftriaxone breakpoints to 1 mcg/mL for METHODS: A retrospective cohort study was conducted at 3 large academic medical centers and included patients with RESULTS: Propensity...

On selecting the critical boundary functions in group-sequential trials with two time-to-event outcomes.

Contemporary clinical trials

Hamasaki T, Hung HMJ, Hsiao CF, Evans SR.
PMID: 33309946
Contemp Clin Trials. 2021 Feb;101:106244. doi: 10.1016/j.cct.2020.106244. Epub 2020 Dec 09.

We investigate selection of critical boundary functions for testing the hypotheses of two time-to-event outcomes as both primary endpoints or a primary and a secondary endpoint in group-sequential clinical trials, where (1) the effect sizes of endpoints are unequal,...

Comparative activity of plazomicin against extended-spectrum cephalosporin-resistant Escherichia coli clinical isolates (2012-2017) in relation to phylogenetic background, sequence type 131 subclones, bla.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology

Johnston BD, Thuras P, Porter SB, Clabots C, Johnson JR.
PMID: 33893571
Eur J Clin Microbiol Infect Dis. 2021 Oct;40(10):2069-2075. doi: 10.1007/s10096-021-04256-9. Epub 2021 Apr 23.

Extended-spectrum cephalosporin-resistant Escherichia coli (ESCREC) are a growing threat. Leading ESCREC lineages include sequence type ST131, especially its (bla

Hospital Infection Control: .

Clinics in colon and rectal surgery

Turner NA, Anderson DJ.
PMID: 32104163
Clin Colon Rectal Surg. 2020 Mar;33(2):98-108. doi: 10.1055/s-0040-1701234. Epub 2020 Feb 25.

No abstract available.

Photo Quiz: Bilateral Necrotizing Pneumonia in a 30-Year-Old Woman, a Hairy Situation.

Journal of clinical microbiology

Almulhim AM, Vellozzi-Averhoff CM, Howard-Anderson J, Babiker A, Kraft CS.
PMID: 33087544
J Clin Microbiol. 2020 Oct 21;58(11). doi: 10.1128/JCM.00451-20. Print 2020 Oct 21.

No abstract available.

Rapid, Sample-to-Answer Host Gene Expression Test to Diagnose Viral Infection.

Open forum infectious diseases

Tsalik EL, Khine A, Talebpour A, Samiei A, Parmar V, Burke TW, Mcclain MT, Ginsburg GS, Woods CW, Henao R, Alavie T.
PMID: 34150923
Open Forum Infect Dis. 2019 Oct 30;6(11):ofz466. doi: 10.1093/ofid/ofz466. eCollection 2019 Nov.

OBJECTIVE: Distinguishing bacterial, viral, or other etiologies of acute illness is diagnostically challenging with significant implications for appropriate antimicrobial use. Host gene expression offers a promising approach, although no clinically useful test has been developed yet to accomplish this....

Evaluating Anti-Infective Drugs in the Resistant Pathogen Setting: Can we Use External Controls?.

Statistical communications in infectious diseases

Evans SR, Powers J.
PMID: 28757914
Stat Commun Infect Dis. 2017;9(1). doi: 10.1515/scid-2016-0003. Epub 2017 Mar 14.

Decreased efficacy of antibiotics due to resistant pathogens has created a need for the development of more effective medical interventions. Despite the increasing prevalence of pathogens resistant to one or more drugs, identifying and enrolling participants into clinical trials...

Showing 1 to 12 of 43 entries