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The analysis of the innate pathways of 5-fluorouracil phosphorylation in human gastrointestinal cancer cell lines in vitro and in vivo.

Oncology reports

Fukushima M, Murakami Y, Suzuki N, Aiba K.
PMID: 21590220
Oncol Rep. 1997 Nov-Dec;4(6):1189-94. doi: 10.3892/or.4.6.1189.

Possible pathways of the phosphorylation of 5-fluorouracil (FUra) were investigated in vitro and in vivo, using certain xenografts, of human gastric and colorectal cancer cell lines. The oxonic acid (Oxo), an inhibitor of orotate phosphoribosyltransferase (OPRTase) that catalyzes the...

Uridine Cytidine Kinase Like-1 Enhances Tumor Cell Proliferation and Mediates Protection from Natural Killer-Mediated Killing.

International journal of immunology and immunotherapy

Gullickson G, Ambrose EC, Hoover RG, Kornbluth J.
PMID: 32083188
Int J Immunol Immunother. 2016;3(1). doi: 10.23937/2378-3672/1410018. Epub 2016 May 24.

Uridine cytidine kinase like-1 (UCKL-1) is a largely uncharacterized protein over-expressed in many tumor cells, especially in highly malignant, aggressive tumors. Sequence analysis indicates that UCKL-1 has homology to uridine kinases, enzymes that play a role in DNA and...

Showing 1 to 2 of 2 entries