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Evolutionary journey of the Gc protein (vitamin D-binding protein) across vertebrates.

Intrinsically disordered proteins

Anwar S, Iqbal MP, Zarina S, Bhutta ZA.
PMID: 28516027
Intrinsically Disord Proteins. 2014 Jan 01;1(1):e27450. doi: 10.4161/idp.27450. eCollection 2013.

With so many diverse functions such as transporter of vitamin D metabolites and fatty acids, actin scavenger and macrophage activating factor, Gc must have been one of the most conserved proteins in animal kingdom. Our objective was to investigate...

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Anwar S, Iqbal MP, Zarina S, et al. Evolutionary journey of the Gc protein (vitamin D-binding protein) across vertebrates. Intrinsically Disord Proteins. 2014;1(1):e27450doi: 10.4161/idp.27450.
Anwar, S., Iqbal, M. P., Zarina, S., & Bhutta, Z. A. (2013). Evolutionary journey of the Gc protein (vitamin D-binding protein) across vertebrates. Intrinsically disordered proteins, 1(1), e27450. https://doi.org/10.4161/idp.27450
Anwar, Shaheena, et al. "Evolutionary journey of the Gc protein (vitamin D-binding protein) across vertebrates." Intrinsically disordered proteins vol. 1,1 (2013): e27450. doi: https://doi.org/10.4161/idp.27450
Anwar S, Iqbal MP, Zarina S, Bhutta ZA. Evolutionary journey of the Gc protein (vitamin D-binding protein) across vertebrates. Intrinsically Disord Proteins. 2014 Jan 01;1(1):e27450. doi: 10.4161/idp.27450. eCollection 2013. PMID: 28516027; PMCID: PMC5424798.
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Investigation of Vitamin D-Binding Protein Polymorphism Impact on Coronary Artery Disease and Relationship with Longevity: Own Data and a Review.

International journal of endocrinology

Stakisaitis D, Lesauskaitė V, Girdauskaitė M, Janulionis E, Ulys A, Benetis R.
PMID: 27143969
Int J Endocrinol. 2016;2016:8347379. doi: 10.1155/2016/8347379. Epub 2016 Apr 06.

The aim of the study was to assess the effect of vitamin D-binding protein (DBP) polymorphism on coronary artery disease (CAD). DBP phenotypes were identified in the groups: control (n = 306), men suffering from CAD (n = 154),...

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Stakisaitis D, Lesauskaitė V, Girdauskaitė M, et al. Investigation of Vitamin D-Binding Protein Polymorphism Impact on Coronary Artery Disease and Relationship with Longevity: Own Data and a Review. Int J Endocrinol. 2016;2016:8347379doi: 10.1155/2016/8347379.
Stakisaitis, D., Lesauskaitė, V., Girdauskaitė, M., Janulionis, E., Ulys, A., & Benetis, R. (2016). Investigation of Vitamin D-Binding Protein Polymorphism Impact on Coronary Artery Disease and Relationship with Longevity: Own Data and a Review. International journal of endocrinology, 20168347379. https://doi.org/10.1155/2016/8347379
Stakisaitis, Donatas, et al. "Investigation of Vitamin D-Binding Protein Polymorphism Impact on Coronary Artery Disease and Relationship with Longevity: Own Data and a Review." International journal of endocrinology vol. 2016 (2016): 8347379. doi: https://doi.org/10.1155/2016/8347379
Stakisaitis D, Lesauskaitė V, Girdauskaitė M, Janulionis E, Ulys A, Benetis R. Investigation of Vitamin D-Binding Protein Polymorphism Impact on Coronary Artery Disease and Relationship with Longevity: Own Data and a Review. Int J Endocrinol. 2016;2016:8347379. doi: 10.1155/2016/8347379. Epub 2016 Apr 06. PMID: 27143969; PMCID: PMC4837253.
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Plasma protein profiling of Mild Cognitive Impairment and Alzheimer's disease using iTRAQ quantitative proteomics.

Proteome science

Song F, Poljak A, Kochan NA, Raftery M, Brodaty H, Smythe GA, Sachdev PS.
PMID: 24433274
Proteome Sci. 2014 Jan 17;12(1):5. doi: 10.1186/1477-5956-12-5.

BACKGROUND: With the promise of disease modifying treatments, there is a need for more specific diagnosis and prognosis of Alzheimer's disease (AD) and mild cognitive impairment (MCI). Plasma biomarkers are likely to be utilised to increase diagnostic accuracy and...

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Song F, Poljak A, Kochan NA, et al. Plasma protein profiling of Mild Cognitive Impairment and Alzheimer's disease using iTRAQ quantitative proteomics. Proteome Sci. 2014;12(1):5doi: 10.1186/1477-5956-12-5.
Song, F., Poljak, A., Kochan, N. A., Raftery, M., Brodaty, H., Smythe, G. A., & Sachdev, P. S. (2014). Plasma protein profiling of Mild Cognitive Impairment and Alzheimer's disease using iTRAQ quantitative proteomics. Proteome science, 12(1), 5. https://doi.org/10.1186/1477-5956-12-5
Song, Fei, et al. "Plasma protein profiling of Mild Cognitive Impairment and Alzheimer's disease using iTRAQ quantitative proteomics." Proteome science vol. 12,1 (2014): 5. doi: https://doi.org/10.1186/1477-5956-12-5
Song F, Poljak A, Kochan NA, Raftery M, Brodaty H, Smythe GA, Sachdev PS. Plasma protein profiling of Mild Cognitive Impairment and Alzheimer's disease using iTRAQ quantitative proteomics. Proteome Sci. 2014 Jan 17;12(1):5. doi: 10.1186/1477-5956-12-5. PMID: 24433274; PMCID: PMC3898732.
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Vitamin D binding protein gene polymorphisms and chronic obstructive pulmonary disease: a meta-analysis.

Journal of thoracic disease

Chen H, Zhang L, He Z, Zhong X, Zhang J, Li M, Bai J.
PMID: 26380769
J Thorac Dis. 2015 Aug;7(8):1423-40. doi: 10.3978/j.issn.2072-1439.2015.08.16.

BACKGROUND: A number of polymorphisms in vitamin D binding protein (VDBP) (GC) gene have been implicated in risk of chronic obstructive pulmonary disease (COPD), but the results were controversial. GC1F, GC1S, and GC2 are three common variants of the...

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Chen H, Zhang L, He Z, et al. Vitamin D binding protein gene polymorphisms and chronic obstructive pulmonary disease: a meta-analysis. J Thorac Dis. 2015;7(8):1423-40doi: 10.3978/j.issn.2072-1439.2015.08.16.
Chen, H., Zhang, L., He, Z., Zhong, X., Zhang, J., Li, M., & Bai, J. (2015). Vitamin D binding protein gene polymorphisms and chronic obstructive pulmonary disease: a meta-analysis. Journal of thoracic disease, 7(8), 1423-40. https://doi.org/10.3978/j.issn.2072-1439.2015.08.16
Chen, Huan, et al. "Vitamin D binding protein gene polymorphisms and chronic obstructive pulmonary disease: a meta-analysis." Journal of thoracic disease vol. 7,8 (2015): 1423-40. doi: https://doi.org/10.3978/j.issn.2072-1439.2015.08.16
Chen H, Zhang L, He Z, Zhong X, Zhang J, Li M, Bai J. Vitamin D binding protein gene polymorphisms and chronic obstructive pulmonary disease: a meta-analysis. J Thorac Dis. 2015 Aug;7(8):1423-40. doi: 10.3978/j.issn.2072-1439.2015.08.16. PMID: 26380769; PMCID: PMC4561265.
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Urinary Vitamin D-Binding Protein as a Biomarker of Steroid-Resistant Nephrotic Syndrome.

Biomarker insights

Bennett MR, Pordal A, Haffner C, Pleasant L, Ma Q, Devarajan P.
PMID: 26792978
Biomark Insights. 2016 Jan 13;11:1-6. doi: 10.4137/BMI.S31633. eCollection 2016.

BACKGROUND: Idiopathic nephrotic syndrome (NS) is one of the most common glomerular disorders of childhood and is associated with increased urinary vitamin D-binding protein (uVDBP) excretion. We tested the hypothesis that uVDBP represents a biomarker to differentiate steroid-resistant nephrotic...

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Bennett MR, Pordal A, Haffner C, et al. Urinary Vitamin D-Binding Protein as a Biomarker of Steroid-Resistant Nephrotic Syndrome. Biomark Insights. 2016;11:1-6doi: 10.4137/BMI.S31633.
Bennett, M. R., Pordal, A., Haffner, C., Pleasant, L., Ma, Q., & Devarajan, P. (2016). Urinary Vitamin D-Binding Protein as a Biomarker of Steroid-Resistant Nephrotic Syndrome. Biomarker insights, 111-6. https://doi.org/10.4137/BMI.S31633
Bennett, Michael R, et al. "Urinary Vitamin D-Binding Protein as a Biomarker of Steroid-Resistant Nephrotic Syndrome." Biomarker insights vol. 11 (2016): 1-6. doi: https://doi.org/10.4137/BMI.S31633
Bennett MR, Pordal A, Haffner C, Pleasant L, Ma Q, Devarajan P. Urinary Vitamin D-Binding Protein as a Biomarker of Steroid-Resistant Nephrotic Syndrome. Biomark Insights. 2016 Jan 13;11:1-6. doi: 10.4137/BMI.S31633. eCollection 2016. PMID: 26792978; PMCID: PMC4712977.
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Evolutionary conservation of equine gc alleles and of Mammalian gc/albumin linkage.

Genetics

Weitkamp LR, Allen PZ.
PMID: 17248956
Genetics. 1979 Aug;92(4):1347-54. doi: 10.1093/genetics/92.4.1347.

Ancient origin of the equine vitamin D binding protein (Gc) polymorphism is suggested by the finding of two alleles, Gc(F) and Gc(S), in each of three equine subgenera, Equus, Asinus and Hippotigris. The equine Gc and albumin loci are...

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Weitkamp LR, Allen PZ. Evolutionary conservation of equine gc alleles and of Mammalian gc/albumin linkage. Genetics. 1979;92(4):1347-54doi: 10.1093/genetics/92.4.1347.
Weitkamp, L. R., & Allen, P. Z. (1979). Evolutionary conservation of equine gc alleles and of Mammalian gc/albumin linkage. Genetics, 92(4), 1347-54. https://doi.org/10.1093/genetics/92.4.1347
Weitkamp, L R, and Allen, P Z. "Evolutionary conservation of equine gc alleles and of Mammalian gc/albumin linkage." Genetics vol. 92,4 (1979): 1347-54. doi: https://doi.org/10.1093/genetics/92.4.1347
Weitkamp LR, Allen PZ. Evolutionary conservation of equine gc alleles and of Mammalian gc/albumin linkage. Genetics. 1979 Aug;92(4):1347-54. doi: 10.1093/genetics/92.4.1347. PMID: 17248956; PMCID: PMC1214075.
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Proteomics analysis of plasma for potential biomarkers in the diagnosis of Alzheimer's disease.

Proteomics. Clinical applications

Liao PC, Yu L, Kuo CC, Lin C, Kuo YM.
PMID: 21136702
Proteomics Clin Appl. 2007 May;1(5):506-12. doi: 10.1002/prca.200600684. Epub 2007 Apr 19.

The objective of this study was to search for biological markers associated with Alzheimer's disease (AD). Plasma specimens obtained from ten pathologically diagnosed AD patients and ten non-demented (ND) control subjects were analyzed by a combination of 2-DE and...

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Liao PC, Yu L, Kuo CC, et al. Proteomics analysis of plasma for potential biomarkers in the diagnosis of Alzheimer's disease. Proteomics Clin Appl. 2007;1(5):506-12doi: 10.1002/prca.200600684.
Liao, P. C., Yu, L., Kuo, C. C., Lin, C., & Kuo, Y. M. (2007). Proteomics analysis of plasma for potential biomarkers in the diagnosis of Alzheimer's disease. Proteomics. Clinical applications, 1(5), 506-12. https://doi.org/10.1002/prca.200600684
Liao, Pao-Chi, et al. "Proteomics analysis of plasma for potential biomarkers in the diagnosis of Alzheimer's disease." Proteomics. Clinical applications vol. 1,5 (2007): 506-12. doi: https://doi.org/10.1002/prca.200600684
Liao PC, Yu L, Kuo CC, Lin C, Kuo YM. Proteomics analysis of plasma for potential biomarkers in the diagnosis of Alzheimer's disease. Proteomics Clin Appl. 2007 May;1(5):506-12. doi: 10.1002/prca.200600684. Epub 2007 Apr 19. PMID: 21136702.
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Pharmacokinetic studies of vitamin D analogues: relationship to vitamin D binding protein (DBP).

Endocrine

Kissmeyer A, Mathiasen IS, Latini S, Binderup L.
PMID: 21153172
Endocrine. 1995 Apr;3(4):263-6. doi: 10.1007/BF03021403.

Vitamin D(3), 25-hydroxyvitamin D(3) (25OHD(3)) and 1α,25-dihydroxyvitamin D(3) (1α,25(OH)(2)D(3)) bind to the vitamin D binding protein (DBP) in the serum. During the development of synthetic vitamin D analogues, it has been shown that the majority of analogues bind to...

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Kissmeyer A, Mathiasen IS, Latini S, et al. Pharmacokinetic studies of vitamin D analogues: relationship to vitamin D binding protein (DBP). Endocrine. 1995;3(4):263-6doi: 10.1007/BF03021403.
Kissmeyer, A., Mathiasen, I. S., Latini, S., & Binderup, L. (1995). Pharmacokinetic studies of vitamin D analogues: relationship to vitamin D binding protein (DBP). Endocrine, 3(4), 263-6. https://doi.org/10.1007/BF03021403
Kissmeyer, A, et al. "Pharmacokinetic studies of vitamin D analogues: relationship to vitamin D binding protein (DBP)." Endocrine vol. 3,4 (1995): 263-6. doi: https://doi.org/10.1007/BF03021403
Kissmeyer A, Mathiasen IS, Latini S, Binderup L. Pharmacokinetic studies of vitamin D analogues: relationship to vitamin D binding protein (DBP). Endocrine. 1995 Apr;3(4):263-6. doi: 10.1007/BF03021403. PMID: 21153172.
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Discrimination of grade 2 and 3 cervical intraepithelial neoplasia by means of analysis of water soluble proteins recovered from cervical biopsies.

Proteome science

Uleberg KE, Munk AC, Brede C, Gudlaugsson E, van Diermen B, Skaland I, Malpica A, Janssen EA, Hjelle A, Baak JP.
PMID: 21711556
Proteome Sci. 2011 Jun 28;9:36. doi: 10.1186/1477-5956-9-36.

BACKGROUND: Cervical intraepithelial neoplasia (CIN) grades 2 and 3 are usually grouped and treated in the same way as "high grade", in spite of their different risk to cancer progression and spontaneous regression rates. CIN2-3 is usually diagnosed in...

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Uleberg KE, Munk AC, Brede C, et al. Discrimination of grade 2 and 3 cervical intraepithelial neoplasia by means of analysis of water soluble proteins recovered from cervical biopsies. Proteome Sci. 2011;9:36doi: 10.1186/1477-5956-9-36.
Uleberg, K. E., Munk, A. C., Brede, C., Gudlaugsson, E., van Diermen, B., Skaland, I., Malpica, A., Janssen, E. A., Hjelle, A., & Baak, J. P. (2011). Discrimination of grade 2 and 3 cervical intraepithelial neoplasia by means of analysis of water soluble proteins recovered from cervical biopsies. Proteome science, 936. https://doi.org/10.1186/1477-5956-9-36
Uleberg, Kai-Erik, et al. "Discrimination of grade 2 and 3 cervical intraepithelial neoplasia by means of analysis of water soluble proteins recovered from cervical biopsies." Proteome science vol. 9 (2011): 36. doi: https://doi.org/10.1186/1477-5956-9-36
Uleberg KE, Munk AC, Brede C, Gudlaugsson E, van Diermen B, Skaland I, Malpica A, Janssen EA, Hjelle A, Baak JP. Discrimination of grade 2 and 3 cervical intraepithelial neoplasia by means of analysis of water soluble proteins recovered from cervical biopsies. Proteome Sci. 2011 Jun 28;9:36. doi: 10.1186/1477-5956-9-36. PMID: 21711556; PMCID: PMC3142202.
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Elevated urinary level of vitamin D-binding protein as a novel biomarker for diabetic nephropathy.

Experimental and therapeutic medicine

Tian XQ, Zhao LM, Ge JP, Zhang Y, Xu YC.
PMID: 24396416
Exp Ther Med. 2014 Feb;7(2):411-416. doi: 10.3892/etm.2013.1426. Epub 2013 Nov 26.

Improving the early prediction and detection of diabetic nephropathy (DN) remains a great challenge in disease management. The aim of this study was to evaluate the early detection power of urinary vitamin D-binding protein (VDBP) for the diagnosis of...

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Tian XQ, Zhao LM, Ge JP, et al. Elevated urinary level of vitamin D-binding protein as a novel biomarker for diabetic nephropathy. Exp Ther Med. 2013;7(2):411-416doi: 10.3892/etm.2013.1426.
Tian, X. Q., Zhao, L. M., Ge, J. P., Zhang, Y., & Xu, Y. C. (2014). Elevated urinary level of vitamin D-binding protein as a novel biomarker for diabetic nephropathy. Experimental and therapeutic medicine, 7(2), 411-416. https://doi.org/10.3892/etm.2013.1426
Tian, Xiao-Qin, et al. "Elevated urinary level of vitamin D-binding protein as a novel biomarker for diabetic nephropathy." Experimental and therapeutic medicine vol. 7,2 (2014): 411-416. doi: https://doi.org/10.3892/etm.2013.1426
Tian XQ, Zhao LM, Ge JP, Zhang Y, Xu YC. Elevated urinary level of vitamin D-binding protein as a novel biomarker for diabetic nephropathy. Exp Ther Med. 2014 Feb;7(2):411-416. doi: 10.3892/etm.2013.1426. Epub 2013 Nov 26. PMID: 24396416; PMCID: PMC3881051.
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Plasma Antimicrobial Peptide LL-37 Level Is Inversely Associated with HDL Cholesterol Level in Patients with Type 2 Diabetes Mellitus.

International journal of endocrinology

Meguro S, Tomita M, Katsuki T, Kato K, Oh H, Ainai A, Ito R, Kawai T, Itoh H, Hasegawa H.
PMID: 24790601
Int J Endocrinol. 2014;2014:703696. doi: 10.1155/2014/703696. Epub 2014 Mar 26.

Introduction. Relation between atherosclerosis and innate immunity has attracted attention. As the antimicrobial peptide, LL-37, could have an important role in atherosclerosis, we supposed that there could be a meaningful association of plasma LL-37 level with risk factors for...

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Meguro S, Tomita M, Katsuki T, et al. Plasma Antimicrobial Peptide LL-37 Level Is Inversely Associated with HDL Cholesterol Level in Patients with Type 2 Diabetes Mellitus. Int J Endocrinol. 2014;2014:703696doi: 10.1155/2014/703696.
Meguro, S., Tomita, M., Katsuki, T., Kato, K., Oh, H., Ainai, A., Ito, R., Kawai, T., Itoh, H., & Hasegawa, H. (2014). Plasma Antimicrobial Peptide LL-37 Level Is Inversely Associated with HDL Cholesterol Level in Patients with Type 2 Diabetes Mellitus. International journal of endocrinology, 2014703696. https://doi.org/10.1155/2014/703696
Meguro, Shu, et al. "Plasma Antimicrobial Peptide LL-37 Level Is Inversely Associated with HDL Cholesterol Level in Patients with Type 2 Diabetes Mellitus." International journal of endocrinology vol. 2014 (2014): 703696. doi: https://doi.org/10.1155/2014/703696
Meguro S, Tomita M, Katsuki T, Kato K, Oh H, Ainai A, Ito R, Kawai T, Itoh H, Hasegawa H. Plasma Antimicrobial Peptide LL-37 Level Is Inversely Associated with HDL Cholesterol Level in Patients with Type 2 Diabetes Mellitus. Int J Endocrinol. 2014;2014:703696. doi: 10.1155/2014/703696. Epub 2014 Mar 26. PMID: 24790601; PMCID: PMC3984791.
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Association of vitamin D deficiency and VDBP gene polymorphism with the risk of AMI in a Pakistani population.

Pakistan journal of medical sciences

Mubashir M, Anwar S, Tareen AK, Mehboobali N, Iqbal K, Iqbal MP.
PMID: 29492057
Pak J Med Sci. 2017 Nov-Dec;33(6):1349-1354. doi: 10.12669/pjms.336.13379.

OBJECTIVE: To investigate the relationship of vitamin D deficiency and risk of AMI in a Pakistani population, and to find out any association between vitamin D binding protein (VDBP) genotypes and risk of AMI in this population.METHODS: In a...

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Mubashir M, Anwar S, Tareen AK, et al. Association of vitamin D deficiency and VDBP gene polymorphism with the risk of AMI in a Pakistani population. Pak J Med Sci. 2017;33(6):1349-1354doi: 10.12669/pjms.336.13379.
Mubashir, M., Anwar, S., Tareen, A. K., Mehboobali, N., Iqbal, K., & Iqbal, M. P. (2017). Association of vitamin D deficiency and VDBP gene polymorphism with the risk of AMI in a Pakistani population. Pakistan journal of medical sciences, 33(6), 1349-1354. https://doi.org/10.12669/pjms.336.13379
Mubashir, Mujtaba, et al. "Association of vitamin D deficiency and VDBP gene polymorphism with the risk of AMI in a Pakistani population." Pakistan journal of medical sciences vol. 33,6 (2017): 1349-1354. doi: https://doi.org/10.12669/pjms.336.13379
Mubashir M, Anwar S, Tareen AK, Mehboobali N, Iqbal K, Iqbal MP. Association of vitamin D deficiency and VDBP gene polymorphism with the risk of AMI in a Pakistani population. Pak J Med Sci. 2017 Nov-Dec;33(6):1349-1354. doi: 10.12669/pjms.336.13379. PMID: 29492057; PMCID: PMC5768823.
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Showing 1 to 12 of 151 entries