Journal of circadian rhythms

Kripke DF, Nievergelt CM, Joo E, Shekhtman T, Kelsoe JR.
PMID: 19166596
J Circadian Rhythms. 2009 Jan 23;7:2. doi: 10.1186/1740-3391-7-2.

BACKGROUND: Clinical symptoms of affective disorders, their response to light treatment, and sensitivity to other circadian interventions indicate that the circadian system has a role in mood disorders. Possibly the mechanisms involve circadian seasonal and photoperiodic mechanisms. Since genetic...

BioData mining

Lekman M, Karlsson R, Graae L, Hössjer O, Kockum I.
PMID: 26692414
BioData Min. 2015 Dec 18;8:42. doi: 10.1186/s13040-015-0076-y. eCollection 2015.

BACKGROUND: The genetic background to bipolar disorder (BPD) has been attributed to different genetic and genomic risk factors. In the present study we hypothesized that inherited copy number variations (CNVs) contribute to susceptibility of BPD. We screened 637 BP-pedigrees...

Neuropsychiatric disease and treatment

Acikel C, Aydin Son Y, Celik C, Gul H.
PMID: 27920536
Neuropsychiatr Dis Treat. 2016 Nov 24;12:2997-3004. doi: 10.2147/NDT.S112558. eCollection 2016.

BACKGROUND: Multifactor dimensionality reduction (MDR) is a nonparametric approach that can be used to detect relevant interactions between single-nucleotide polymorphisms (SNPs). The aim of this study was to build the best genomic model based on SNP associations and to...