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Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.

Hypertension (Dallas, Tex. : 1979)

Wain LV, Vaez A, Jansen R, Joehanes R, van der Most PJ, Erzurumluoglu AM, O'Reilly PF, Cabrera CP, Warren HR, Rose LM, Verwoert GC, Hottenga JJ, Strawbridge RJ, Esko T, Arking DE, Hwang SJ, Guo X, Kutalik Z, Trompet S, Shrine N, Teumer A, Ried JS, Bis JC, Smith AV, Amin N, Nolte IM, Lyytikäinen LP, Mahajan A, Wareham NJ, Hofer E, Joshi PK, Kristiansson K, Traglia M, Havulinna AS, Goel A, Nalls MA, Sõber S, Vuckovic D, Luan J, Del Greco M F, Ayers KL, Marrugat J, Ruggiero D, Lopez LM, Niiranen T, Enroth S, Jackson AU, Nelson CP, Huffman JE, Zhang W, Marten J, Gandin I, Harris SE, Zemunik T, Lu Y, Evangelou E, Shah N, de Borst MH, Mangino M, Prins BP, Campbell A, Li-Gao R, Chauhan G, Oldmeadow C, Abecasis G, Abedi M, Barbieri CM, Barnes MR, Batini C, Beilby J, Blake T, Boehnke M, Bottinger EP, Braund PS, Brown M, Brumat M, Campbell H, Chambers JC, Cocca M, Collins F, Connell J, Cordell HJ, Damman JJ, Davies G, de Geus EJ, de Mutsert R, Deelen J, Demirkale Y, Doney ASF, Dörr M, Farrall M, Ferreira T, Frånberg M, Gao H, Giedraitis V, Gieger C, Giulianini F, Gow AJ, Hamsten A, Harris TB, Hofman A, Holliday EG, Hui J, Jarvelin MR, Johansson Å, Johnson AD, Jousilahti P, Jula A, Kähönen M, Kathiresan S, Khaw KT, Kolcic I, Koskinen S, Langenberg C, Larson M, Launer LJ, Lehne B, Liewald DCM, Lin L, Lind L, Mach F, Mamasoula C, Menni C, Mifsud B, Milaneschi Y, Morgan A, Morris AD, Morrison AC, Munson PJ, Nandakumar P, Nguyen QT, Nutile T, Oldehinkel AJ, Oostra BA, Org E, Padmanabhan S, Palotie A, Paré G, Pattie A, Penninx BWJH, Poulter N, Pramstaller PP, Raitakari OT, Ren M, Rice K, Ridker PM, Riese H, Ripatti S, Robino A, Rotter JI, Rudan I, Saba Y, Saint Pierre A, Sala CF, Sarin AP, Schmidt R, Scott R, Seelen MA, Shields DC, Siscovick D, Sorice R, Stanton A, Stott DJ, Sundström J, Swertz M, Taylor KD, Thom S, Tzoulaki I, Tzourio C, Uitterlinden AG, Völker U, Vollenweider P, Wild S, Willemsen G, Wright AF, Yao J, Thériault S, Conen D, Attia J, Sever P, Debette S, Mook-Kanamori DO, Zeggini E, Spector TD, van der Harst P, Palmer CNA, Vergnaud AC, Loos RJF, Polasek O, Starr JM, Girotto G, Hayward C, Kooner JS, Lindgren CM, Vitart V, Samani NJ, Tuomilehto J, Gyllensten U, Knekt P, Deary IJ, Ciullo M, Elosua R, Keavney BD, Hicks AA, Scott RA, Gasparini P, Laan M, Liu Y, Watkins H, Hartman CA, Salomaa V, Toniolo D, Perola M, Wilson JF, Schmidt H, Zhao JH, Lehtimäki T, van Duijn CM, Gudnason V, Psaty BM, Peters A, Rettig R, James A, Jukema JW, Strachan DP, Palmas W, Metspalu A, Ingelsson E, Boomsma DI, Franco OH, Bochud M, Newton-Cheh C, Munroe PB, Elliott P, Chasman DI, Chakravarti A, Knight J, Morris AP, Levy D, Tobin MD, Snieder H, Caulfield MJ, Ehret GB.
PMID: 28739976
Hypertension. 2017 Jul 24; doi: 10.1161/HYPERTENSIONAHA.117.09438. Epub 2017 Jul 24.

Elevated blood pressure is a major risk factor for cardiovascular disease and has a substantial genetic contribution. Genetic variation influencing blood pressure has the potential to identify new pharmacological targets for the treatment of hypertension. To discover additional novel...

Cite
Wain LV, Vaez A, Jansen R, et al. Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney. Hypertension. 2017;doi: 10.1161/HYPERTENSIONAHA.117.09438.
Wain, L. V., Vaez, A., Jansen, R., Joehanes, R., van der Most, P. J., Erzurumluoglu, A. M., O'Reilly, P. F., Cabrera, C. P., Warren, H. R., Rose, L. M., Verwoert, G. C., Hottenga, J. J., Strawbridge, R. J., Esko, T., Arking, D. E., Hwang, S. J., Guo, X., Kutalik, Z., Trompet, S., Shrine, N., Teumer, A., Ried, J. S., Bis, J. C., Smith, A. V., Amin, N., Nolte, I. M., Lyytikäinen, L. P., Mahajan, A., Wareham, N. J., Hofer, E., Joshi, P. K., Kristiansson, K., Traglia, M., Havulinna, A. S., Goel, A., Nalls, M. A., Sõber, S., Vuckovic, D., Luan, J., Del Greco M, F., Ayers, K. L., Marrugat, J., Ruggiero, D., Lopez, L. M., Niiranen, T., Enroth, S., Jackson, A. U., Nelson, C. P., Huffman, J. E., Zhang, W., Marten, J., Gandin, I., Harris, S. E., Zemunik, T., Lu, Y., Evangelou, E., Shah, N., de Borst, M. H., Mangino, M., Prins, B. P., Campbell, A., Li-Gao, R., Chauhan, G., Oldmeadow, C., Abecasis, G., Abedi, M., Barbieri, C. M., Barnes, M. R., Batini, C., Beilby, J., Blake, T., Boehnke, M., Bottinger, E. P., Braund, P. S., Brown, M., Brumat, M., Campbell, H., Chambers, J. C., Cocca, M., Collins, F., Connell, J., Cordell, H. J., Damman, J. J., Davies, G., de Geus, E. J., de Mutsert, R., Deelen, J., Demirkale, Y., Doney, A. S. F., Dörr, M., Farrall, M., Ferreira, T., Frånberg, M., Gao, H., Giedraitis, V., Gieger, C., Giulianini, F., Gow, A. J., Hamsten, A., Harris, T. B., Hofman, A., Holliday, E. G., Hui, J., Jarvelin, M. R., Johansson, �. �., Johnson, A. D., Jousilahti, P., Jula, A., Kähönen, M., Kathiresan, S., Khaw, K. T., Kolcic, I., Koskinen, S., Langenberg, C., Larson, M., Launer, L. J., Lehne, B., Liewald, D. C. M., Lin, L., Lind, L., Mach, F., Mamasoula, C., Menni, C., Mifsud, B., Milaneschi, Y., Morgan, A., Morris, A. D., Morrison, A. C., Munson, P. J., Nandakumar, P., Nguyen, Q. T., Nutile, T., Oldehinkel, A. J., Oostra, B. A., Org, E., Padmanabhan, S., Palotie, A., Paré, G., Pattie, A., Penninx, B. W. J. H., Poulter, N., Pramstaller, P. P., Raitakari, O. T., Ren, M., Rice, K., Ridker, P. M., Riese, H., Ripatti, S., Robino, A., Rotter, J. I., Rudan, I., Saba, Y., Saint Pierre, A., Sala, C. F., Sarin, A. P., Schmidt, R., Scott, R., Seelen, M. A., Shields, D. C., Siscovick, D., Sorice, R., Stanton, A., Stott, D. J., Sundström, J., Swertz, M., Taylor, K. D., Thom, S., Tzoulaki, I., Tzourio, C., Uitterlinden, A. G., Völker, U., Vollenweider, P., Wild, S., Willemsen, G., Wright, A. F., Yao, J., Thériault, S., Conen, D., Attia, J., Sever, P., Debette, S., Mook-Kanamori, D. O., Zeggini, E., Spector, T. D., van der Harst, P., Palmer, C. N. A., Vergnaud, A. C., Loos, R. J. F., Polasek, O., Starr, J. M., Girotto, G., Hayward, C., Kooner, J. S., Lindgren, C. M., Vitart, V., Samani, N. J., Tuomilehto, J., Gyllensten, U., Knekt, P., Deary, I. J., Ciullo, M., Elosua, R., Keavney, B. D., Hicks, A. A., Scott, R. A., Gasparini, P., Laan, M., Liu, Y., Watkins, H., Hartman, C. A., Salomaa, V., Toniolo, D., Perola, M., Wilson, J. F., Schmidt, H., Zhao, J. H., Lehtimäki, T., van Duijn, C. M., Gudnason, V., Psaty, B. M., Peters, A., Rettig, R., James, A., Jukema, J. W., Strachan, D. P., Palmas, W., Metspalu, A., Ingelsson, E., Boomsma, D. I., Franco, O. H., Bochud, M., Newton-Cheh, C., Munroe, P. B., Elliott, P., Chasman, D. I., Chakravarti, A., Knight, J., Morris, A. P., Levy, D., Tobin, M. D., Snieder, H., Caulfield, M. J., & Ehret, G. B. (2017). Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney. Hypertension (Dallas, Tex. : 1979), . https://doi.org/10.1161/HYPERTENSIONAHA.117.09438
Wain, Louise V, et al. "Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney." Hypertension (Dallas, Tex. : 1979) vol. (2017). doi: https://doi.org/10.1161/HYPERTENSIONAHA.117.09438
Wain LV, Vaez A, Jansen R, Joehanes R, van der Most PJ, Erzurumluoglu AM, O'Reilly PF, Cabrera CP, Warren HR, Rose LM, Verwoert GC, Hottenga JJ, Strawbridge RJ, Esko T, Arking DE, Hwang SJ, Guo X, Kutalik Z, Trompet S, Shrine N, Teumer A, Ried JS, Bis JC, Smith AV, Amin N, Nolte IM, Lyytikäinen LP, Mahajan A, Wareham NJ, Hofer E, Joshi PK, Kristiansson K, Traglia M, Havulinna AS, Goel A, Nalls MA, Sõber S, Vuckovic D, Luan J, Del Greco M F, Ayers KL, Marrugat J, Ruggiero D, Lopez LM, Niiranen T, Enroth S, Jackson AU, Nelson CP, Huffman JE, Zhang W, Marten J, Gandin I, Harris SE, Zemunik T, Lu Y, Evangelou E, Shah N, de Borst MH, Mangino M, Prins BP, Campbell A, Li-Gao R, Chauhan G, Oldmeadow C, Abecasis G, Abedi M, Barbieri CM, Barnes MR, Batini C, Beilby J, Blake T, Boehnke M, Bottinger EP, Braund PS, Brown M, Brumat M, Campbell H, Chambers JC, Cocca M, Collins F, Connell J, Cordell HJ, Damman JJ, Davies G, de Geus EJ, de Mutsert R, Deelen J, Demirkale Y, Doney ASF, Dörr M, Farrall M, Ferreira T, Frånberg M, Gao H, Giedraitis V, Gieger C, Giulianini F, Gow AJ, Hamsten A, Harris TB, Hofman A, Holliday EG, Hui J, Jarvelin MR, Johansson Å, Johnson AD, Jousilahti P, Jula A, Kähönen M, Kathiresan S, Khaw KT, Kolcic I, Koskinen S, Langenberg C, Larson M, Launer LJ, Lehne B, Liewald DCM, Lin L, Lind L, Mach F, Mamasoula C, Menni C, Mifsud B, Milaneschi Y, Morgan A, Morris AD, Morrison AC, Munson PJ, Nandakumar P, Nguyen QT, Nutile T, Oldehinkel AJ, Oostra BA, Org E, Padmanabhan S, Palotie A, Paré G, Pattie A, Penninx BWJH, Poulter N, Pramstaller PP, Raitakari OT, Ren M, Rice K, Ridker PM, Riese H, Ripatti S, Robino A, Rotter JI, Rudan I, Saba Y, Saint Pierre A, Sala CF, Sarin AP, Schmidt R, Scott R, Seelen MA, Shields DC, Siscovick D, Sorice R, Stanton A, Stott DJ, Sundström J, Swertz M, Taylor KD, Thom S, Tzoulaki I, Tzourio C, Uitterlinden AG, Völker U, Vollenweider P, Wild S, Willemsen G, Wright AF, Yao J, Thériault S, Conen D, Attia J, Sever P, Debette S, Mook-Kanamori DO, Zeggini E, Spector TD, van der Harst P, Palmer CNA, Vergnaud AC, Loos RJF, Polasek O, Starr JM, Girotto G, Hayward C, Kooner JS, Lindgren CM, Vitart V, Samani NJ, Tuomilehto J, Gyllensten U, Knekt P, Deary IJ, Ciullo M, Elosua R, Keavney BD, Hicks AA, Scott RA, Gasparini P, Laan M, Liu Y, Watkins H, Hartman CA, Salomaa V, Toniolo D, Perola M, Wilson JF, Schmidt H, Zhao JH, Lehtimäki T, van Duijn CM, Gudnason V, Psaty BM, Peters A, Rettig R, James A, Jukema JW, Strachan DP, Palmas W, Metspalu A, Ingelsson E, Boomsma DI, Franco OH, Bochud M, Newton-Cheh C, Munroe PB, Elliott P, Chasman DI, Chakravarti A, Knight J, Morris AP, Levy D, Tobin MD, Snieder H, Caulfield MJ, Ehret GB. Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney. Hypertension. 2017 Jul 24; doi: 10.1161/HYPERTENSIONAHA.117.09438. Epub 2017 Jul 24. PMID: 28739976; PMCID: PMC5783787.
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The Italian version of the NEO PI-R: Conceptual and empirical support for the use of targeted rotation.

Personality and individual differences

Terracciano A.
PMID: 19002272
Pers Individ Dif. 2003;35(8):1859-1872. doi: 10.1016/S0191-8869(03)00035-7.

Earlier cross-cultural research on replicability of the Revised NEO Personality Inventory (NEO-PI-R) suggested that personality trait structure is universal, but a recent study using an Italian translation has challenged this position. The present article reexamines the psychometric properties of...

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Terracciano A. The Italian version of the NEO PI-R: Conceptual and empirical support for the use of targeted rotation. Pers Individ Dif. 2003;35(8):1859-1872doi: 10.1016/S0191-8869(03)00035-7.
Terracciano, A. (2003). The Italian version of the NEO PI-R: Conceptual and empirical support for the use of targeted rotation. Personality and individual differences, 35(8), 1859-1872. https://doi.org/10.1016/S0191-8869(03)00035-7
Terracciano, Antonio. "The Italian version of the NEO PI-R: Conceptual and empirical support for the use of targeted rotation." Personality and individual differences vol. 35,8 (2003): 1859-1872. doi: https://doi.org/10.1016/S0191-8869(03)00035-7
Terracciano A. The Italian version of the NEO PI-R: Conceptual and empirical support for the use of targeted rotation. Pers Individ Dif. 2003;35(8):1859-1872. doi: 10.1016/S0191-8869(03)00035-7. PMID: 19002272; PMCID: PMC2581832.
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A population scale analysis of rare SNCA variation in the UK Biobank.

Neurobiology of disease

Blauwendraat C, Makarious MB, Leonard HL, Bandres-Ciga S, Iwaki H, Nalls MA, Noyce AJ, Singleton AB.
PMID: 33307186
Neurobiol Dis. 2021 Jan;148:105182. doi: 10.1016/j.nbd.2020.105182. Epub 2020 Dec 08.

Parkinson's disease (PD) is a complex neurodegenerative disease with a variety of genetic and environmental factors contributing to disease. The SNCA gene encodes for the alpha-synuclein protein which plays a central role in PD, where aggregates of this protein...

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Blauwendraat C, Makarious MB, Leonard HL, et al. A population scale analysis of rare SNCA variation in the UK Biobank. Neurobiol Dis. 2020;148:105182doi: 10.1016/j.nbd.2020.105182.
Blauwendraat, C., Makarious, M. B., Leonard, H. L., Bandres-Ciga, S., Iwaki, H., Nalls, M. A., Noyce, A. J., & Singleton, A. B. (2021). A population scale analysis of rare SNCA variation in the UK Biobank. Neurobiology of disease, 148105182. https://doi.org/10.1016/j.nbd.2020.105182
Blauwendraat, Cornelis, et al. "A population scale analysis of rare SNCA variation in the UK Biobank." Neurobiology of disease vol. 148 (2021): 105182. doi: https://doi.org/10.1016/j.nbd.2020.105182
Blauwendraat C, Makarious MB, Leonard HL, Bandres-Ciga S, Iwaki H, Nalls MA, Noyce AJ, Singleton AB. A population scale analysis of rare SNCA variation in the UK Biobank. Neurobiol Dis. 2021 Jan;148:105182. doi: 10.1016/j.nbd.2020.105182. Epub 2020 Dec 08. PMID: 33307186; PMCID: PMC7880248.
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Cerebral aggregate g-ratio mapping using magnetic resonance relaxometry and diffusion tensor imaging to investigate sex and age-related differences in white matter microstructure.

Magnetic resonance imaging

Cortina LE, Kim RW, Kiely M, Triebswetter C, Gong Z, Alsameen MH, Bouhrara M.
PMID: 34678436
Magn Reson Imaging. 2022 Jan;85:87-92. doi: 10.1016/j.mri.2021.10.019. Epub 2021 Oct 19.

Axonal demyelination is a cardinal feature of aging and age-related diseases. The g-ratio, mathematically defined as the inner-to-outer diameter of a myelinated axon, is used as a structural index of optimal axonal myelination and has been shown to represent...

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Cortina LE, Kim RW, Kiely M, et al. Cerebral aggregate g-ratio mapping using magnetic resonance relaxometry and diffusion tensor imaging to investigate sex and age-related differences in white matter microstructure. Magn Reson Imaging. 2021;85:87-92doi: 10.1016/j.mri.2021.10.019.
Cortina, L. E., Kim, R. W., Kiely, M., Triebswetter, C., Gong, Z., Alsameen, M. H., & Bouhrara, M. (2022). Cerebral aggregate g-ratio mapping using magnetic resonance relaxometry and diffusion tensor imaging to investigate sex and age-related differences in white matter microstructure. Magnetic resonance imaging, 8587-92. https://doi.org/10.1016/j.mri.2021.10.019
Cortina, Luis E, et al. "Cerebral aggregate g-ratio mapping using magnetic resonance relaxometry and diffusion tensor imaging to investigate sex and age-related differences in white matter microstructure." Magnetic resonance imaging vol. 85 (2022): 87-92. doi: https://doi.org/10.1016/j.mri.2021.10.019
Cortina LE, Kim RW, Kiely M, Triebswetter C, Gong Z, Alsameen MH, Bouhrara M. Cerebral aggregate g-ratio mapping using magnetic resonance relaxometry and diffusion tensor imaging to investigate sex and age-related differences in white matter microstructure. Magn Reson Imaging. 2022 Jan;85:87-92. doi: 10.1016/j.mri.2021.10.019. Epub 2021 Oct 19. PMID: 34678436; PMCID: PMC8629921.
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Vascular risk is not associated with PET measures of Alzheimer's disease neuropathology among cognitively normal older adults.

Neuroimage. Reports

Bilgel M, Bannerjee A, Shafer A, An Y, Resnick SM.
PMID: 34927122
Neuroimage Rep. 2021 Dec;1(4). doi: 10.1016/j.ynirp.2021.100068. Epub 2021 Nov 29.

Cardiovascular disease (CVD) is associated with a higher risk of developing dementia. Studies have found that vascular risk factors are associated with greater amyloid-β (Aβ) and tau burden, which are hallmark neuropathologies of Alzheimer's disease (AD). Evidence for these...

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Bilgel M, Bannerjee A, Shafer A, et al. Vascular risk is not associated with PET measures of Alzheimer's disease neuropathology among cognitively normal older adults. Neuroimage Rep. 2021;1(4)doi: 10.1016/j.ynirp.2021.100068.
Bilgel, M., Bannerjee, A., Shafer, A., An, Y., & Resnick, S. M. (2021). Vascular risk is not associated with PET measures of Alzheimer's disease neuropathology among cognitively normal older adults. Neuroimage. Reports, 1(4), . https://doi.org/10.1016/j.ynirp.2021.100068
Bilgel, Murat, et al. "Vascular risk is not associated with PET measures of Alzheimer's disease neuropathology among cognitively normal older adults." Neuroimage. Reports vol. 1,4 (2021). doi: https://doi.org/10.1016/j.ynirp.2021.100068
Bilgel M, Bannerjee A, Shafer A, An Y, Resnick SM. Vascular risk is not associated with PET measures of Alzheimer's disease neuropathology among cognitively normal older adults. Neuroimage Rep. 2021 Dec;1(4). doi: 10.1016/j.ynirp.2021.100068. Epub 2021 Nov 29. PMID: 34927122; PMCID: PMC8682073.
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Stable analogs of 13‑hydroxy-9,10-trans-epoxy-(11E)-octadecenoate (13,9-HEL), an oxidized derivative of linoleic acid implicated in the epidermal skin barrier.

Prostaglandins, leukotrienes, and essential fatty acids

Keyes GS, Maiden K, Ramsden CE.
PMID: 34749189
Prostaglandins Leukot Essent Fatty Acids. 2021 Nov;174:102357. doi: 10.1016/j.plefa.2021.102357. Epub 2021 Oct 24.

Hydroxy-epoxy- and trihydroxy derivatives of linoleic acid are proposed to play an essential function in formation of the mammalian skin permeability barrier, which could account for the essential nature of its precursor, linoleic acid. Recent literature suggests that a...

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Keyes GS, Maiden K, Ramsden CE. Stable analogs of 13‑hydroxy-9,10-trans-epoxy-(11E)-octadecenoate (13,9-HEL), an oxidized derivative of linoleic acid implicated in the epidermal skin barrier. Prostaglandins Leukot Essent Fatty Acids. 2021;174:102357doi: 10.1016/j.plefa.2021.102357.
Keyes, G. S., Maiden, K., & Ramsden, C. E. (2021). Stable analogs of 13‑hydroxy-9,10-trans-epoxy-(11E)-octadecenoate (13,9-HEL), an oxidized derivative of linoleic acid implicated in the epidermal skin barrier. Prostaglandins, leukotrienes, and essential fatty acids, 174102357. https://doi.org/10.1016/j.plefa.2021.102357
Keyes, Gregory S, et al. "Stable analogs of 13‑hydroxy-9,10-trans-epoxy-(11E)-octadecenoate (13,9-HEL), an oxidized derivative of linoleic acid implicated in the epidermal skin barrier." Prostaglandins, leukotrienes, and essential fatty acids vol. 174 (2021): 102357. doi: https://doi.org/10.1016/j.plefa.2021.102357
Keyes GS, Maiden K, Ramsden CE. Stable analogs of 13‑hydroxy-9,10-trans-epoxy-(11E)-octadecenoate (13,9-HEL), an oxidized derivative of linoleic acid implicated in the epidermal skin barrier. Prostaglandins Leukot Essent Fatty Acids. 2021 Nov;174:102357. doi: 10.1016/j.plefa.2021.102357. Epub 2021 Oct 24. PMID: 34749189; PMCID: PMC8595794.
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Red cell distribution width, anemia and their associations with white matter integrity among middle-aged urban adults.

Neurobiology of aging

Beydoun MA, Shaked D, Hossain S, Weiss J, Beydoun HA, Maldonado AI, Katzel LI, Davatzikos C, Gullapalli RP, Seliger SL, Erus G, Evans MK, Zonderman AB, Waldstein SR.
PMID: 34120091
Neurobiol Aging. 2021 Sep;105:229-240. doi: 10.1016/j.neurobiolaging.2021.05.004. Epub 2021 May 21.

Anemia (blood hemoglobin [Hb]

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Beydoun MA, Shaked D, Hossain S, et al. Red cell distribution width, anemia and their associations with white matter integrity among middle-aged urban adults. Neurobiol Aging. 2021;105:229-240doi: 10.1016/j.neurobiolaging.2021.05.004.
Beydoun, M. A., Shaked, D., Hossain, S., Weiss, J., Beydoun, H. A., Maldonado, A. I., Katzel, L. I., Davatzikos, C., Gullapalli, R. P., Seliger, S. L., Erus, G., Evans, M. K., Zonderman, A. B., & Waldstein, S. R. (2021). Red cell distribution width, anemia and their associations with white matter integrity among middle-aged urban adults. Neurobiology of aging, 105229-240. https://doi.org/10.1016/j.neurobiolaging.2021.05.004
Beydoun, May A, et al. "Red cell distribution width, anemia and their associations with white matter integrity among middle-aged urban adults." Neurobiology of aging vol. 105 (2021): 229-240. doi: https://doi.org/10.1016/j.neurobiolaging.2021.05.004
Beydoun MA, Shaked D, Hossain S, Weiss J, Beydoun HA, Maldonado AI, Katzel LI, Davatzikos C, Gullapalli RP, Seliger SL, Erus G, Evans MK, Zonderman AB, Waldstein SR. Red cell distribution width, anemia and their associations with white matter integrity among middle-aged urban adults. Neurobiol Aging. 2021 Sep;105:229-240. doi: 10.1016/j.neurobiolaging.2021.05.004. Epub 2021 May 21. PMID: 34120091; PMCID: PMC8338752.
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LRRK2 recruitment, activity, and function in organelles.

The FEBS journal

Bonet-Ponce L, Cookson MR.
PMID: 34196120
FEBS J. 2021 Jul 01; doi: 10.1111/febs.16099. Epub 2021 Jul 01.

Protein coding mutations in leucine-rich repeat kinase 2 (LRRK2) cause familial Parkinson's disease (PD), and noncoding variations around the gene increase the risk of developing sporadic PD. It is generally accepted that pathogenic LRRK2 mutations increase LRRK2 kinase activity,...

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Bonet-Ponce L, Cookson MR. LRRK2 recruitment, activity, and function in organelles. FEBS J. 2021;doi: 10.1111/febs.16099.
Bonet-Ponce, L., & Cookson, M. R. (2021). LRRK2 recruitment, activity, and function in organelles. The FEBS journal, . https://doi.org/10.1111/febs.16099
Bonet-Ponce, Luis, and Cookson, Mark R. "LRRK2 recruitment, activity, and function in organelles." The FEBS journal vol. (2021). doi: https://doi.org/10.1111/febs.16099
Bonet-Ponce L, Cookson MR. LRRK2 recruitment, activity, and function in organelles. FEBS J. 2021 Jul 01; doi: 10.1111/febs.16099. Epub 2021 Jul 01. PMID: 34196120; PMCID: PMC8744135.
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Molecular Pathways Linking Oxylipins to Nociception in Rats.

The journal of pain

Domenichiello AF, Sapio MR, Loydpierson AJ, Maric D, Goto T, Horowitz MS, Keyes GS, Yuan ZX, Majchrzak-Hong SF, Mannes AJ, Iadarola MJ, Ramsden CE.
PMID: 33031942
J Pain. 2021 Mar;22(3):275-299. doi: 10.1016/j.jpain.2020.09.001. Epub 2020 Oct 06.

Oxylipins are lipid peroxidation products that participate in nociceptive, inflammatory, and vascular responses to injury. Effects of oxylipins depend on tissue-specific differences in accumulation of precursor polyunsaturated fatty acids and the expression of specific enzymes to transform the precursors....

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Domenichiello AF, Sapio MR, Loydpierson AJ, et al. Molecular Pathways Linking Oxylipins to Nociception in Rats. J Pain. 2020;22(3):275-299doi: 10.1016/j.jpain.2020.09.001.
Domenichiello, A. F., Sapio, M. R., Loydpierson, A. J., Maric, D., Goto, T., Horowitz, M. S., Keyes, G. S., Yuan, Z. X., Majchrzak-Hong, S. F., Mannes, A. J., Iadarola, M. J., & Ramsden, C. E. (2021). Molecular Pathways Linking Oxylipins to Nociception in Rats. The journal of pain, 22(3), 275-299. https://doi.org/10.1016/j.jpain.2020.09.001
Domenichiello, Anthony F, et al. "Molecular Pathways Linking Oxylipins to Nociception in Rats." The journal of pain vol. 22,3 (2021): 275-299. doi: https://doi.org/10.1016/j.jpain.2020.09.001
Domenichiello AF, Sapio MR, Loydpierson AJ, Maric D, Goto T, Horowitz MS, Keyes GS, Yuan ZX, Majchrzak-Hong SF, Mannes AJ, Iadarola MJ, Ramsden CE. Molecular Pathways Linking Oxylipins to Nociception in Rats. J Pain. 2021 Mar;22(3):275-299. doi: 10.1016/j.jpain.2020.09.001. Epub 2020 Oct 06. PMID: 33031942; PMCID: PMC7954900.
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Intra-individual Change in Personality Stability and Age.

Journal of research in personality

Terracciano A, McCrae RR, Costa PT.
PMID: 20305728
J Res Pers. 2010 Feb 01;44(1):31-37. doi: 10.1016/j.jrp.2009.09.006.

The stability of individual differences in personality traits is typically examined at the group level with test-retest correlations across two assessments. For 684 subjects (age range 17-76) we computed individual coefficients from three sequential assessments to evaluate intra-individual (i.e.,...

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Terracciano A, McCrae RR, Costa PT. Intra-individual Change in Personality Stability and Age. J Res Pers. 2010;44(1):31-37doi: 10.1016/j.jrp.2009.09.006.
Terracciano, A., McCrae, R. R., & Costa, P. T. (2010). Intra-individual Change in Personality Stability and Age. Journal of research in personality, 44(1), 31-37. https://doi.org/10.1016/j.jrp.2009.09.006
Terracciano, Antonio, et al. "Intra-individual Change in Personality Stability and Age." Journal of research in personality vol. 44,1 (2010): 31-37. doi: https://doi.org/10.1016/j.jrp.2009.09.006
Terracciano A, McCrae RR, Costa PT. Intra-individual Change in Personality Stability and Age. J Res Pers. 2010 Feb 01;44(1):31-37. doi: 10.1016/j.jrp.2009.09.006. PMID: 20305728; PMCID: PMC2839250.
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Perceptions of Americans and the Iraq Invasion: Implications for Understanding National Character Stereotypes.

Journal of cross-cultural psychology

Terracciano A, McCrae RR.
PMID: 18618011
J Cross Cult Psychol. 2007;38(6):695-710. doi: 10.1177/0022022107308586.

This study examines perceptions of the "typical American" from 49 cultures around the world. Contrary to the ethnocentric bias hypothesis, we found strong agreement between in-group and out-group ratings on the American profile (assertive, open-minded, but antagonistic); Americans in...

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Terracciano A, McCrae RR. Perceptions of Americans and the Iraq Invasion: Implications for Understanding National Character Stereotypes. J Cross Cult Psychol. 2007;38(6):695-710doi: 10.1177/0022022107308586.
Terracciano, A., & McCrae, R. R. (2007). Perceptions of Americans and the Iraq Invasion: Implications for Understanding National Character Stereotypes. Journal of cross-cultural psychology, 38(6), 695-710. https://doi.org/10.1177/0022022107308586
Terracciano, Antonio, and McCrae, Robert R. "Perceptions of Americans and the Iraq Invasion: Implications for Understanding National Character Stereotypes." Journal of cross-cultural psychology vol. 38,6 (2007): 695-710. doi: https://doi.org/10.1177/0022022107308586
Terracciano A, McCrae RR. Perceptions of Americans and the Iraq Invasion: Implications for Understanding National Character Stereotypes. J Cross Cult Psychol. 2007;38(6):695-710. doi: 10.1177/0022022107308586. PMID: 18618011; PMCID: PMC2447921.
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Autobiographical Memory Phenomenology and Content Mediate Attachment Style and Psychological Distress.

Journal of counseling psychology

Sutin AR, Gillath O.
PMID: 20706555
J Couns Psychol. 2009 Jul 01;56(3):351-364. doi: 10.1037/a0014917.

In two studies, the present research tested the phenomenology and content of autobiographical memory as distinct mediators between attachment avoidance and anxiety and depressive symptoms. In Study 1, participants (N = 454) completed measures of attachment and depressive symptoms...

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Sutin AR, Gillath O. Autobiographical Memory Phenomenology and Content Mediate Attachment Style and Psychological Distress. J Couns Psychol. 2009;56(3):351-364doi: 10.1037/a0014917.
Sutin, A. R., & Gillath, O. (2009). Autobiographical Memory Phenomenology and Content Mediate Attachment Style and Psychological Distress. Journal of counseling psychology, 56(3), 351-364. https://doi.org/10.1037/a0014917
Sutin, Angelina R, and Gillath, Omri. "Autobiographical Memory Phenomenology and Content Mediate Attachment Style and Psychological Distress." Journal of counseling psychology vol. 56,3 (2009): 351-364. doi: https://doi.org/10.1037/a0014917
Sutin AR, Gillath O. Autobiographical Memory Phenomenology and Content Mediate Attachment Style and Psychological Distress. J Couns Psychol. 2009 Jul 01;56(3):351-364. doi: 10.1037/a0014917. PMID: 20706555; PMCID: PMC2919846.
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